A subject this map covers
Neuroprotection
What belongs here
Attempts to stop the second, delayed wave of damage in the first hours and days.
What does not belong here, however close it looks
Restoring function lost months earlier is repair, not neuroprotection.
What has been looked at
Counted from what the sources catalogue, not from reading the work. It says how much exists and over what span of years — never what any of it found.
- Registered or indexed as work in people: 1169 records · 1978–2027
- Indexed as work in animals: 1885 records · 1977–2026
- Indexed as laboratory work: 80 records · 1996–2026
- The source has not said who or what was studied: 572 records · 1991–2026
- No matching published catalogue records are linked above. Human-review status must be checked on the evidence itself.
Published in this map
Catalogue records matching this subject. Publication here does not establish human review, measured results or effectiveness. Open a record to inspect its sources and evidence.
No published catalogue records match this subject yet.
This is a result within this map, not a claim that no research exists. The source records below can help you continue searching.
Found in the scientific sources, not yet checked
Titles and identifiers as the sources publish them. Nobody here has read these papers, and nothing on this shelf is a result, a recommendation or evidence that anything works. Each line opens the original.
3706 records
This grouping is the source's own cataloguing, not a reading of the paper. It says where a record was filed, not what it found.
Registered or indexed as work in people
- Thoracic ossification of the posterior longitudinal ligament, ossification of the yellow ligament from T9-T12 with superimposed acute T10/T11 disc herniation: controversies in surgical management. — PubMed · 1996 · Case Reports
- Initial stabilization and medical management of acute spinal cord injury. — PubMed · 1996 · Journal Article
- Injury zone denervation in traumatic quadriplegia in humans. — PubMed · 1996 · Journal Article
- New pharmacologic approaches to acute spinal cord injury. — PubMed · 1996 · Journal Article
- Neurotoxic versus neuroprotective actions of endogenous opioid peptides: implications for treatment of CNS injury. — PubMed · 1996 · Journal Article
- [The physiopathology of acute spinal cord injury and a hope for a successful treatment]. — PubMed · 1996 · English Abstract
- Transient traumatic quadriplegia in a 29-year-old man without predisposing anatomic lesion. — PubMed · 1995 · Case Reports
- Update on the pathophysiology and pathology of acute spinal cord injury. — PubMed · 1995 · Journal Article
- Clinical potential for the use of neuroprotective agents. A brief overview. — PubMed · 1995 · Journal Article
- Glucocorticoid therapy of spinal cord injury. — PubMed · 1994 · Journal Article
- Surveillance of spinal cord motor and sensory function. — PubMed · 1993 · Journal Article
- Neuroprotective actions of glucocorticoid and nonglucocorticoid steroids in acute neuronal injury. — PubMed · 1993 · Journal Article
- Lipid antioxidants in acute central nervous system injury. — PubMed · 1993 · Journal Article
- Pathophysiology of spinal cord trauma. — PubMed · 1993 · Journal Article
- Methylprednisolone after spinal cord injury. — PubMed · 1993 · Journal Article
- Experimental neurobiology of central nervous system trauma. — PubMed · 1993 · Journal Article
- Secondary injury mechanisms in acute spinal cord injury. — PubMed · 1993 · Clinical Trial
- The role of oxygen radicals in traumatic injury: clinical implications. — PubMed · 1993 · Journal Article
- Biochemistry and pharmacology of lipid antioxidants in acute brain and spinal cord injury. — PubMed · 1992 · Journal Article
- Monosialogangliosides, neuroprotection, and neuronal repair processes. — PubMed · 1992 · Journal Article
- Demyelination in spinal cord injury and multiple sclerosis: what can we do to enhance functional recovery? — PubMed · 1992 · Journal Article
- Spinal cord injury: preventing secondary injury. — PubMed · 1992 · Journal Article
- [Anesthesia of patients with injury to the cervical spine]. — PubMed · 1992 · English Abstract
- Pharmacological strategies in CNS trauma. — PubMed · 1992 · Journal Article
- Review of the secondary injury theory of acute spinal cord trauma with emphasis on vascular mechanisms. — PubMed · 1991 · Journal Article
- Review of experimental spinal cord injury with emphasis on the local and systemic circulatory effects. — PubMed · 1991 · Journal Article
- The spinal cord injury problem--a review. — PubMed · 1986 · Journal Article
- Neuropeptides and central nervous system injury. Clinical implications. — PubMed · 1986 · Journal Article
- Multiple level spinal injuries: importance of early recognition. — PubMed · 1978 · Journal Article
Indexed as work in animals
- Hypertonic saline protects the axo-myelinic interface acutely after contusive SCI and improves postural stability and balance as revealed by motion sequencing (MoSeq). — PubMed · 2026 · Journal Article
- Machine learning-assisted prediction of PANoptosis-related molecular targets and precise screening of neuroprotective drugs for spinal cord injury. — PubMed · 2026 · Journal Article
- Tanshinone IIA promotes mitophagy by inhibiting the MARCHF5-mediated ubiquitination and degradation of FUNDC1 to alleviate spinal cord injury. — PubMed · 2026 · Journal Article
- Targeting sphingosine-1-phosphate receptor-2 attenuates spinal cord injury by preventing neuronal ferroptosis. — PubMed · 2026 · Journal Article
- Thiorphan improves motor function after spinal cord injury by inhibiting neuronal ferroptosis in female mice. — PubMed · 2026 · Journal Article
- Ultrasound Shear-wave Elastography Reveals Biomechanical Heterogeneity Following Acute Spinal Cord Injury. — PubMed · 2026 · Journal Article
- Tamoxifen Modulates Spinal Cord Injury Repair Via CCL2/CCR2 Axis and its Mechanisms. — PubMed · 2026 · Journal Article
- A multi-omics atlas reveals spatially resolved sphingolipid metabolic reprogramming after spinal cord injury. — PubMed · 2026 · Journal Article
- Andrographolide attenuates neuroinflammation and apoptosis after spinal cord injury via PI3K-Akt pathway activation. — PubMed · 2026 · Journal Article
- Astragaloside IV enhances autophagy to suppress endoplasmic reticulum stress and pyroptosis after spinal cord injury. — PubMed · 2026 · Journal Article
- Edaravone attenuates ACSL4-dependent ferroptosis in spinal motor neurons following cardiac arrest in rats. — PubMed · 2026 · Journal Article
- Inadvertent p75NTR signaling might cause inconsistencies in the neuroprotection offered by mesenchymal stem cells. — PubMed · 2026 · Journal Article
- Photobiomodulation therapy and polyethylene glycol as monotherapy versus combination treatment in male and female rats following spinal cord injury. — PubMed · 2026 · Journal Article
- Targeting the PARP1-p53 Axis Could Mitigate Necrotic-Apoptotic Signaling and Secondary Neurodegeneration After Spinal Cord Injury. — PubMed · 2026 · Journal Article
- Every-Other-Day Fasting Prehabilitation Attenuates Secondary Injury Following Spinal Cord Injury and Is Associated with Stage-Dependent SREBP1-Related Metabolic-Immune Remodeling. — PubMed · 2026 · Journal Article
- Nanoformulated fingolimod attenuates NLRP3 inflammasome activation and promotes functional recovery in a rat model of spinal cord injury. — PubMed · 2026 · Journal Article
- Skeletal muscle lysate derived macroporous hydrogel repairs spinal cord injury via immunoregulation and axon regeneration. — PubMed · 2026 · Journal Article
- Gomisin A exerts neuroprotective effects on spinal cord injury through the EGFR/JAK2/STAT3 signaling pathway to inhibit ferroptosis. — PubMed · 2026 · Journal Article
- Nanoparticle Modulation of Immune and Vascular Microenvironment Dynamics Following Spinal Cord Injury. — PubMed · 2026 · Journal Article
- Nuclear heme oxygenase-1 enhances blood-spinal cord barrier repair via corticotropin-releasing hormone-mediated tight junction phosphorylation. — PubMed · 2026 · Journal Article
- K777 promotes functional recovery after spinal cord injury via the PI3K/AKT signaling pathway. — PubMed · 2026 · Journal Article
- Dynamic ROS-responsive injectable hydrogel incorporating nanozymes for spinal cord repair by alleviating oxidative stress and neuronal ferroptosis. — PubMed · 2026 · Journal Article
- Elamipretide (SS-31) promotes recovery by preserving mitochondrial bioenergetics and neural remodeling after spinal cord injury. — PubMed · 2026 · Journal Article
- Novel Neurotrophin-3 peptidomimetic synthetic neurotrophin promotes neurological recovery after spinal cord injury. — PubMed · 2026 · Journal Article
- Rhynchophylline inhibits cluster of differentiation 36 (CD36) on endothelial cells to reduce fibrotic scar formation and enhance functional recovery after spinal cord injury. — PubMed · 2026 · Journal Article
- Tetramethylpyrazine promotes spinal cord injury repair by modulating macrophage M1/M2 polarization via inhibition of the IL-6/JAK2/STAT3 pathway. — PubMed · 2026 · Journal Article
- A zinc-coordinated cascade-responsive therapeutic nanoassembly for remodeling the pathological microenvironment and restoring mitochondrial homeostasis in spinal cord injury. — PubMed · 2026 · Journal Article
- Engineered CCR2 positive macrophages coordinate immunoregulation with neural regeneration and matrix remodeling after spinal cord injury. — PubMed · 2026 · Journal Article
- PLD3-mediated Mitophagy Attenuates Neuronal Ferroptosis and Promotes Functional Recovery after Spinal Cord Injury. — PubMed · 2026 · Journal Article
- Herkinorin Exerted Neuroprotective Effects After Spinal Cord Injury by Suppression of NF-κB Pathway Activation. — PubMed · 2026 · Journal Article
- Liproxstatin-1 improves functional recovery after acute spinal cord injury by inhibiting ferroptosis-induced inflammation. — PubMed · 2026 · Journal Article
Where this was looked for, and when
The latest collection walk and the accumulated shelf have different scopes. A zero applies only to that source query and its date window; older records may remain on the shelf. It does not mean no research exists.
| ClinicalTrials.gov | latest collection walk returned no records | asked on 2026-10-05 Collection window: 2026-09-16 – 2026-10-05 | matched in this collection walk 0 · accumulated records across collection walks 6 · still to fetch in this walk 0 | aim: every record matching this question |
|---|---|---|---|---|
| Crossref | asked, and it answered | asked on 2026-09-16 Collection window: all dates before the end date – 2026-09-16 | matched in this collection walk 1230843 · accumulated records across collection walks 50 | aim: a sample of the most relevant records. This source ranks a bag of words, so its own total is the size of the corpus that shares some of them, never a set still owed. |
| PubMed | asked, and it answered | asked on 2026-09-17 Collection window: all dates before the end date – 2026-09-17 | matched in this collection walk 3744 · accumulated records across collection walks 3744 · still to fetch in this walk 0 | aim: every record matching this question |
The question asked
- ClinicalTrials.gov
("neuroprotection" OR "secondary injury") - Crossref
spinal cord injury neuroprotection secondary injury - PubMed
("Spinal Cord Injuries"[MeSH Terms] OR "spinal cord injury"[Title/Abstract] OR "spinal cord injuries"[Title/Abstract] OR "spinal cord trauma"[Title/Abstract]) AND ("Neuroprotection"[MeSH Terms] OR "Neuroprotective Agents"[MeSH Terms] OR "neuroprotection"[Title/Abstract] OR "secondary injury"[Title/Abstract])