A subject this map covers
Neuroprotection
What belongs here
Attempts to stop the second, delayed wave of damage in the first hours and days.
What does not belong here, however close it looks
Restoring function lost months earlier is repair, not neuroprotection.
What has been looked at
Counted from what the sources catalogue, not from reading the work. It says how much exists and over what span of years — never what any of it found.
- Registered or indexed as work in people: 1169 records · 1978–2027
- Indexed as work in animals: 1885 records · 1977–2026
- Indexed as laboratory work: 80 records · 1996–2026
- The source has not said who or what was studied: 572 records · 1991–2026
- No matching published catalogue records are linked above. Human-review status must be checked on the evidence itself.
Published in this map
Catalogue records matching this subject. Publication here does not establish human review, measured results or effectiveness. Open a record to inspect its sources and evidence.
No published catalogue records match this subject yet.
This is a result within this map, not a claim that no research exists. The source records below can help you continue searching.
Found in the scientific sources, not yet checked
Titles and identifiers as the sources publish them. Nobody here has read these papers, and nothing on this shelf is a result, a recommendation or evidence that anything works. Each line opens the original.
3706 records
This grouping is the source's own cataloguing, not a reading of the paper. It says where a record was filed, not what it found.
Indexed as work in animals
- TRIM32 Alleviates the Inflammation in Spinal Cord Injury Progression Through Inducing the Ubiquitination Degradation of TLR4. — PubMed · 2026 · Journal Article
- USP5-C-MAF Axis Regulates Autophagy-Dependent Neuronal Ferroptosis in Spinal Cord Injury Therapeutics. — PubMed · 2026 · Journal Article
- Mitochondrial-Inflammatory Axis Dysregulation Triggers Disulfidptosis and the Multifaceted Protective Mechanism of Bisphenol A Following Spinal Cord Injury. — PubMed · 2026 · Journal Article
- Multifunctional Nanozyme Hydrogel for Oxidative Stress Scavenging and Mitophagy Activation in Spinal Cord Injury Repair. — PubMed · 2026 · Journal Article
- Nanozyme-Switched Efferocytosis Initiation Platform Orchestrates Pathological Network Reprogramming to Promote Functional Recovery after Spinal Cord Injury. — PubMed · 2026 · Journal Article
- Nyap1 Redirects JNK Signaling to Couple Neuroprotection with Circuit Regeneration After Spinal Cord Injury. — PubMed · 2026 · Journal Article
- Protective effect and possible mechanisms of resveratrol in animal models of spinal cord injury: a preclinical systematic review and meta-analysis. — PubMed · 2026 · Journal Article
- Dose and parameter specific effects of curcumin on neuropathic pain, cavity formation, and non-coding RNA expression in a spinal cord injury model. — PubMed · 2026 · Journal Article
- Sodium Alginate Hydrogel with Zinc Ion Nanoparticles for Synergistic Neuroprotection and Functional Recovery in Spinal Cord Injury. — PubMed · 2026 · Journal Article
- Identification of a mitochondrial biomarker signature linking neuroinflammation to neuronal dysfunction in spinal cord injury. — PubMed · 2026 · Journal Article
- SGK1 inhibition supports neuroprotection in spinal cord injury by suppressing oxidative stress and AIM2 activation via FoxO1 mediated mitophagy. — PubMed · 2026 · Journal Article
- Acute Administration of Ampakine CX1739 after Cervical Spinal Cord Injury. — PubMed · 2026 · Journal Article
- Agarotetrol attenuates spinal cord injury by targeting PPARγ to modulate microglial activation. — PubMed · 2026 · Journal Article
- Amiodarone Improves Locomotor Function in Experimental Spinal Cord Injury by Reducing Secondary Axonal Degeneration and White Matter Atrophy. — PubMed · 2026 · Journal Article
- Deferoxamine mitigates neuronal loss following spinal cord injury via ferroptosis inhibition and Nrf2/HO‑1 pathway activation. — PubMed · 2026 · Journal Article
- DLK inhibition has sex-specific effects on neuroprotection and locomotor recovery after spinal cord injury. — PubMed · 2026 · Journal Article
- Hyaluronic Acid Hydrogel-Mediated Delivery of MSC-Derived Exo-FGF21 Promotes Spinal Cord Injury Repair via STAT3/SOCS3 Signaling. — PubMed · 2026 · Journal Article
- Netrin-1 Therapy Restores Partial Hindlimb Movement in a Rat Model of High-Severity Chronic Spinal Cord Injury. — PubMed · 2026 · Journal Article
- Spatiotemporal PET imaging of P2X7R-driven neuroinflammation using [(18)F]GSK1482160 after experimental acute spinal cord injury in mice. — PubMed · 2026 · Journal Article
- An Iron-Scavenging and Hydrogen-Releasing Microneedle Patch Suppresses Ferroptosis and Promotes Spinal Cord Repair. — PubMed · 2026 · Journal Article
- Repurposing Dexmedetomidine: Early Pharmacological Hypothermia Enhances Neuroprotection and Improves Locomotor and Bladder Functional Recovery after Spinal Cord Injury. — PubMed · 2026 · Journal Article
- Dual-targeting nanoparticles enhance microglial P2Y12R expression to promote neuronal mitophagy for repairing spinal cord injury. — PubMed · 2026 · Journal Article
- Electroacupuncture alleviates depression-like behavior after spinal cord injury via SIRT1/HMGB1 signaling axis mediated ferroptosis. — PubMed · 2026 · Journal Article
- Acute cardio-centric haemodynamic management preserves chronic cardiovascular function in pigs with high-thoracic spinal cord injury. — PubMed · 2026 · Journal Article
- Hybrid Cryomicroneedles Enhance DC Vaccine Efficacy and Function as Non-Typical Artificial Tertiary Lymphoid Structures to Provide Neuroprotective Immunity in Spinal Cord Injury. — PubMed · 2026 · Journal Article
- Low-Intensity Pulsed Ultrasound Promotes Spinal Cord Injury Recovery by Regulating Microglia-Mediated Neuroinflammation. — PubMed · 2026 · Journal Article
- SYK-dependent lipid handling in monocyte-derived macrophages governs functional recovery after spinal cord injury. — PubMed · 2026 · Journal Article
- Targeting Glutamate Excitotoxicity With Memantine Modulates Glial Response and Protects Motoneurons After Spinal Root Lesion. — PubMed · 2026 · Journal Article
- Targeting miR-499-5p for neuroprotection in spinal cord injury: Implications for inflammation and ROS-induced neuronal damage. — PubMed · 2026 · Journal Article
- Zinc protects against neuroinflammation after spinal cord injury by regulating mitophagy-dependent mtDNA-cGAS-STING signaling. — PubMed · 2026 · Journal Article
- Neural Stem Cell-Derived Exosomes-Transmitted miR-31-5p Promote Functional Recovery of Spinal Cord Injury by Shifting Astrocytes A1/A2 Polarization. — PubMed · 2026 · Journal Article
- Propentofylline and Interleukin-4 Modulate Lesion-Associated Myeloid Responses and Improve Functional Recovery After Spinal Cord Injury. — PubMed · 2026 · Journal Article
- Protocol to develop a preclinical severe contusive-compressive SCI mouse model for translational research. — PubMed · 2026 · Journal Article
- Anti-inflammatory treatment confirms rsfMRI and TSPO PET as biomarkers of functional connectivity and neuroinflammation in rat contusion spinal cord injuries. — PubMed · 2026 · Journal Article
- Obacunone Promotes Functional Recovery After Spinal Cord Injury by Attenuating Neuroinflammation by Targeting the TLR4/MyD88/p38 MAPK Pathway. — PubMed · 2026 · Journal Article
- A novel schisantherin B-loaded Prussian blue nanozyme for treating spinal cord injury. — PubMed · 2026 · Journal Article
- Time-dependent adaptations of damaged neurons and their microenvironment in the regenerating adult zebrafish spinal cord. — PubMed · 2026 · Journal Article
- Focal Estrogen Therapy in Male Rats Promotes Neuronal Survival and Reduces Denervation Atrophy After Spinal Cord Injury via Modulation of β-Catenin and NF-κB. — PubMed · 2026 · Journal Article
- Cerebrolysin-loaded platelet-rich plasma exosomes: Restoring immune homeostasis via TNF-α/IL-10 modulation and apoptosis targeting for spinal cord injury repair. — PubMed · 2026 · Journal Article
- Effects of Acetyl-l-Carnitine on the Mitophagy in the Spinal Cord Injury Progression Through PINK/Parkin Pathway. — PubMed · 2026 · Journal Article
- Green Synthesis, Chemical Characterization, and Assessment of the Neuroprotective Properties of Zinc Nanoparticles on the Spinal Cord Injury Contusive Model in Rats. — PubMed · 2026 · Journal Article
- Midkine Overexpression Promotes Functional Recovery After Spinal Cord Injury by Enhancing Microglial Efferocytosis Via LRP-1. — PubMed · 2026 · Journal Article
- Postinjury Carnosine Treatment Prevents Neurotrophic Factor Decline in Denervated Muscle and Spinal Cord After Traumatic Injury. — PubMed · 2026 · Journal Article
- Sequential dual-drug delivery biomimetic hydrogel for temporal orchestration of acute neuroprotection and chronic regeneration in spinal cord injury. — PubMed · 2026 · Journal Article
- Therapeutic Potential of Photobiomodulation in Early Recovery After Experimental Spinal Cord Injury in Rats: Histological and Biomechanical Analysis. — PubMed · 2026 · Journal Article
- Sirtuin1 modulates P53/Nrf2 pathway to promote spinal cord injury repair. — PubMed · 2026 · Journal Article
- Nanoparticle-Assembled Multifaceted Hydrogel Therapy Promotes Functional Recovery After Spinal Cord Injury. — PubMed · 2026 · Journal Article
- Glaucocalyxin A Promotes Spinal Cord Repair By Nrf2/HO-1 Pathway Activation to Suppress AIM2 Inflammasome Formation. — PubMed · 2026 · Journal Article
- TMEM106A deficiency in microglia attenuates functional recovery after spinal cord injury by exacerbating neuroinflammation. — PubMed · 2026 · Journal Article
- A dual-action nanoparticle approach for spinal cord injury treatment: ferroptosis inhibition, inflammation control, and Myelin preservation. — PubMed · 2026 · Journal Article
- Opuntia ficus-indica (L.) Mill. Extract: From Chemical Characterization to Inflammatory Profiling and Its Potential Effects in a Zebrafish Model of Spinal Cord Injury-A Morphological and Molecular Study. — PubMed · 2026 · Journal Article
- CREB5 Inhibits Neuronal Ferroptosis via Transactivating ApoL6 to Regulate Lipid Droplet Metabolism After Spinal Cord Injury. — PubMed · 2026 · Journal Article
- Immuno-Neuroprotectants Facilitate Neurological Recovery via Sequestration of Neutrophil Extracellular Traps (NETs) and Promotion of Neuroregeneration. — PubMed · 2026 · Journal Article
- Local release of fibroblast growth factor 21 and cannabidiol promoting spinal cord nerve injury repair through activation of cannabinoid receptor 2. — PubMed · 2026 · Journal Article
- Morusin Alleviates Spinal Cord Injury in Rats by Regulating Macrophage Reprogramming Through Targeting RELA and NRF2. — PubMed · 2026 · Journal Article
- Naringenin alleviates spinal cord injury by ameliorating macrophage/microglia autophagy via progranulin stabilisation. — PubMed · 2026 · Journal Article
- Neuroprotective effects of dexmedetomidine in spinal cord injury via modulating PERK/ATF4 pathway. — PubMed · 2026 · Journal Article
- Phillyrin Ameliorates Traumatic Spinal Cord Injury by Inhibiting Inflammation, Oxidative Stress, and Pyroptosis Through Modulation of the Nrf2/HO-1 Signaling Pathway. — PubMed · 2026 · Journal Article
- The role of the iron-chelating agent deferoxamine in spinal cord injury: a systematic review and meta-analysis of preclinical studies. — PubMed · 2026 · Journal Article
- TREM2 Facilitates Myelin Debris Clearance but Exacerbates Chronic Inflammation and Fibrosis After Spinal Cord Injury. — PubMed · 2026 · Journal Article
Where this was looked for, and when
The latest collection walk and the accumulated shelf have different scopes. A zero applies only to that source query and its date window; older records may remain on the shelf. It does not mean no research exists.
| ClinicalTrials.gov | latest collection walk returned no records | asked on 2026-10-05 Collection window: 2026-09-16 – 2026-10-05 | matched in this collection walk 0 · accumulated records across collection walks 6 · still to fetch in this walk 0 | aim: every record matching this question |
|---|---|---|---|---|
| Crossref | asked, and it answered | asked on 2026-09-16 Collection window: all dates before the end date – 2026-09-16 | matched in this collection walk 1230843 · accumulated records across collection walks 50 | aim: a sample of the most relevant records. This source ranks a bag of words, so its own total is the size of the corpus that shares some of them, never a set still owed. |
| PubMed | asked, and it answered | asked on 2026-09-17 Collection window: all dates before the end date – 2026-09-17 | matched in this collection walk 3744 · accumulated records across collection walks 3744 · still to fetch in this walk 0 | aim: every record matching this question |
The question asked
- ClinicalTrials.gov
("neuroprotection" OR "secondary injury") - Crossref
spinal cord injury neuroprotection secondary injury - PubMed
("Spinal Cord Injuries"[MeSH Terms] OR "spinal cord injury"[Title/Abstract] OR "spinal cord injuries"[Title/Abstract] OR "spinal cord trauma"[Title/Abstract]) AND ("Neuroprotection"[MeSH Terms] OR "Neuroprotective Agents"[MeSH Terms] OR "neuroprotection"[Title/Abstract] OR "secondary injury"[Title/Abstract])