A subject this map covers
Neuroprotection
What belongs here
Attempts to stop the second, delayed wave of damage in the first hours and days.
What does not belong here, however close it looks
Restoring function lost months earlier is repair, not neuroprotection.
What has been looked at
Counted from what the sources catalogue, not from reading the work. It says how much exists and over what span of years — never what any of it found.
- Registered or indexed as work in people: 1169 records · 1978–2027
- Indexed as work in animals: 1885 records · 1977–2026
- Indexed as laboratory work: 80 records · 1996–2026
- The source has not said who or what was studied: 572 records · 1991–2026
- No matching published catalogue records are linked above. Human-review status must be checked on the evidence itself.
Published in this map
Catalogue records matching this subject. Publication here does not establish human review, measured results or effectiveness. Open a record to inspect its sources and evidence.
No published catalogue records match this subject yet.
This is a result within this map, not a claim that no research exists. The source records below can help you continue searching.
Found in the scientific sources, not yet checked
Titles and identifiers as the sources publish them. Nobody here has read these papers, and nothing on this shelf is a result, a recommendation or evidence that anything works. Each line opens the original.
3706 records
This grouping is the source's own cataloguing, not a reading of the paper. It says where a record was filed, not what it found.
Indexed as work in animals
- Evaluation of Polyphenol-Rich Lemon Peel Extract Use in a Zebrafish Model of Spinal Cord Injury: Morphology, Repair-Associated Markers, and Inflammatory Profile. — PubMed · 2026 · Journal Article
- Clusterin Inhibits Neuronal Ferroptosis via the PI3K-AKT-mTOR-SREBP1 Axis to Promote Functional Recovery after Spinal Cord Injury. — PubMed · 2026 · Journal Article
- Multimodal electroconductive PLGA-based scaffold orchestrates neuroprotection and regeneration following severe spinal cord injury. — PubMed · 2026 · Journal Article
- A translational preclinical strategy for chronic spinal cord injury: neuroprotective and regenerative potential of botulinum neurotoxin type A combined with muscle atrophy prevention via electrostimulation. — PubMed · 2026 · Journal Article
- Autophagy activation by the Becn1(F121A) mutation reprograms neuroinflammation and promotes neurological recovery after spinal cord injury. — PubMed · 2026 · Journal Article
- Buyang Huanwu decoction facilitates the repair of red nucleus neurons subsequent to spinal cord injury in rats via autophagy. — PubMed · 2026 · Journal Article
- Cinnamaldehyde mitigates spinal cord injury in rats through anti-inflammatory and anti-apoptotic pathways. — PubMed · 2026 · Journal Article
- Clinical features, diagnostic imaging findings, treatment, and outcome of a cat with C4 vertebral fracture and concomitant tracheal rupture. — PubMed · 2026 · Case Reports
- Effects of AC-SDKP administration on the NLRP3 inflammasome complex and blood-spinal cord barrier in experimental spinal cord injury. — PubMed · 2026 · Journal Article
- Limited effects of the REV-ERB agonist SR9009 after mouse spinal cord contusion: Reduced acute pathology with unaffected functional recovery and chronic white matter loss. — PubMed · 2026 · Journal Article
- Lysine-polydopamine nanoparticles for ameliorating acidic microenvironment and neuroprotection in spinal cord injury repair. — PubMed · 2026 · Journal Article
- MK-2206 dihydrochloride ameliorates the neuronal function in spinal cord injured rats by reducing oxidative stress and modulating the PI3K/Akt pathway. — PubMed · 2026 · Journal Article
- N-acetylcysteine loaded electrospun core/shell nanofibers: a promising system for ferroptosis in spinal cord injury. — PubMed · 2026 · Journal Article
- Nanogel Integrated Zwitterionic Injectable Hydrogel with Sequential Drug-Releasing Capability for the Programmable Repair of Spinal Cord Injury. — PubMed · 2026 · Journal Article
- Neuroprotection and Axonal Regeneration via ECM-Mimetic Nanofibers Incorporating Metal-Phenolic Network Nanoparticles Toward Spinal Cord Injury Repair. — PubMed · 2026 · Journal Article
- Neuroprotective effects of pregabalin in experimental spinal cord injury: An investigation of oxidative stress and antioxidant enzymes in blood and neural tissue. — PubMed · 2026 · Journal Article
- Olfactory ensheathing cell transplantation targets macrophage extracellular traps and NKCC1 to alleviate pain after spinal cord injury. — PubMed · 2026 · Journal Article
- Paeoniflorin Ameliorates Spinal Cord Injury by Controlling Apoptosis and Ferroptosis in H(2)O(2)-Damaged PC12 Cells. — PubMed · 2026 · Journal Article
- Pharmacological Inhibition of EZH2 by GSK-343 Attenuates Neuroinflammation in a Mouse Model of Spinal Cord Injury. — PubMed · 2026 · Journal Article
- Schisantherin B exerts therapeutic effects on spinal cord injury via the PI3K/AKT signaling pathway. — PubMed · 2026 · Journal Article
- Silencing miR-134-5p promotes functional recovery after spinal cord injury by activating brain-derived neurotrophic factor (BDNF). — PubMed · 2026 · Journal Article
- Targeting the Spinal Cord-Brain Axis: Electroacupuncture Mitigates Remote Frontal Cortex Neuroinflammation via HMGB1/TLR4 to Aid Functional Recovery After Spinal Cord Injury. — PubMed · 2026 · Journal Article
- Uric Acid Released from Poly (Lactic-co-Glycolic Acid) Nanoparticles Mitigates Glutamate-Induced Excitotoxicity of Spinal Cord Neurons. — PubMed · 2026 · Journal Article
- circ-Ttc3 alleviates LPS-induced neuronal injury via stabilizing RBFOX1 to inhibit inflammation and oxidative stress. — PubMed · 2025 · Journal Article
- AAD-2004 through clearing H(2)O(2) reduces astrocyte proliferation and promotes neural regeneration after spinal cord injury. — PubMed · 2025 · Journal Article
- Removal or inhibition of transglutaminase 2 decreases cellular stress, supporting tissue preservation, and recovery after SCI. — PubMed · 2025 · Journal Article
- Sappanone A Promotes Motor Function Recovery in Spinal Cord Injury Mice by Inhibiting Microglial M1 Polarization via Activation of the Keap1/Nrf2 Pathway. — PubMed · 2025 · Journal Article
- Engineered lesion-homing liposomes encapsulating Rosuvastatin enhance spinal cord injury repair by preventing the formation of foamy macrophages. — PubMed · 2025 · Journal Article
- Ubiquitin-specific protease 14 inhibition promotes mitophagy and attenuates neural apoptosis after spinal cord injury. — PubMed · 2025 · Journal Article
- Cabazitaxel Sustained-Release Nanoparticles Treat Spinal Cord Injury through Inhibiting Fibrin Deposition and Improving the Microenvironment. — PubMed · 2025 · Journal Article
- SIK2 mediated mitochondrial homeostasis in spinal cord injury: modulating oxidative stress and the AIM2 inflammasome via CRTC1/CREB signaling. — PubMed · 2025 · Journal Article
- The protective role of nuclear Heme oxygenase-1 in blood-spinal cord barrier after hypoxia in vitro. — PubMed · 2025 · Journal Article
- Acute administration of tibolone reduces oxidative stress and inflammation in a rat model of traumatic spinal cord injury. — PubMed · 2025 · Journal Article
- Farrerol confers neuroprotection in spinal cord injury by regulating macrophages/microglia polarization through the JAK2/STAT3 pathway. — PubMed · 2025 · Journal Article
- Galanin-Mediated Inflammatory Responses in Zebrafish Spinal Cord Regeneration. — PubMed · 2025 · Journal Article
- Melatonin Attenuates Spinal Cord Injury by Regulating Ferroptosis Through the Nrf2/HO-1/GPX4 Pathway. — PubMed · 2025 · Journal Article
- Pain after traumatic brain injury (TBI) fosters hemorrhage at the site of injury. — PubMed · 2025 · Journal Article
- Relieving intraspinal pressure acutely after cervical spinal cord injury improves functional outcomes. — PubMed · 2025 · Journal Article
- SCO-Spondin-Derived Peptide NX210 Promotes Functional Recovery after Spinal Cord Injury in Mice. — PubMed · 2025 · Journal Article
- Synthesis of novel pyrazole derivatives and neuroprotective effect investigation. — PubMed · 2025 · Journal Article
- Juglone promotes spinal cord injury recovery by suppressing pyroptosis and necroptosis through FOS/USP53/ubiquitination. — PubMed · 2025 · Journal Article
- Spinal cord injury alters the therapeutic potential of olfactory ensheathing cells harvested in an autologous transplantation model. — PubMed · 2025 · Journal Article
- Tetramethylpyrazine Promotes Functional Recovery after Spinal Cord Injury by Regulating 5-Methylcytosine RNA Modification via the NSUN2-XBP1 Axis. — PubMed · 2025 · Journal Article
- Dihydroquercetin ameliorates spinal cord injury in rats by modulating the AKT/Nrf2/GPX4 signaling pathway-mediated ferroptosis. — PubMed · 2025 · Journal Article
- Function of orthologous fibroblast growth factor 11 protein in angiogenesis and immunomodulatory after spinal cord injury. — PubMed · 2025 · Journal Article
- Hyperoside alleviates macrophages and microglia-mediated neuroinflammation and oxidative stress through activating PI3K/AKT and Nrf2/HO-1 signaling pathway post spinal cord injury. — PubMed · 2025 · Journal Article
- Rolipram-Loaded PgP Nanotherapeutics via Intrathecal Administration Reduces Secondary Injury in a Rat Acute Moderate Contusion SCI Model. — PubMed · 2025 · Journal Article
- Salvigenin mitigates neuronal ferroptosis by binding to PI3K and enhancing the interaction between VCP and PI3K in the repair of spinal cord injury. — PubMed · 2025 · Journal Article
- Semax peptide targets the μ opioid receptor gene Oprm1 to promote deubiquitination and functional recovery after spinal cord injury in female mice. — PubMed · 2025 · Journal Article
- The neuroprotective effect of Salvia przewalskii extract of total phenolic acids for the treatment of acute spinal cord injury in rats. — PubMed · 2025 · Journal Article
- 1,8-Cineole alleviates spinal cord injury by inhibiting microglial pyroptosis via the P38 MAPK and PI3K/AKT/NLRP3 signaling pathways to protects neurons. — PubMed · 2025 · Journal Article
- MYCN-mediated pyroptosis and inflammation in the molecular mechanism of MicroRNA-202-3P promote functional recovery in spinal cord injury. — PubMed · 2025 · Journal Article
- Abscisic Acid Regulates Immune-inflammatory Responses to Induce Neuroprotection in Spinal Cord Injury: Insights from Gene Expression and Network Analysis. — PubMed · 2025 · Journal Article
- Poliumoside Alleviates Neuroinflammation and Oxidative Stress After Spinal Cord Injury by Activating the PI3K/AKT/mTOR Signaling Pathway. — PubMed · 2025 · Journal Article
- POU6F1 promote lumbar motor circuit reorganization following spinal cord injury. — PubMed · 2025 · Journal Article
- GDF11 alleviates spinal cord injury in rats by modulating microglia polarization through Smad2/3 and MAPK/NFκB signaling pathways. — PubMed · 2025 · Journal Article
- Activation of SIRT3 / PRDX5 signaling inhibits apoptosis after acute spinal cord injury in mice. — PubMed · 2025 · Journal Article
- Evaluation of Neuroprotective and Neuroregenerative Potential of NeuroAiD™ II(MLC901) in a Rat Model of Kainic Acid-Induced Spinal Cord Injury. — PubMed · 2025 · Journal Article
- Investigating the Effects of Epac2 Activation in an In Vitro Cortical Mechanical Injury Model for Central Nervous System Repair. — PubMed · 2025 · Journal Article
- Long-term dynamics of the spinal cord injury neuroinflammatory response and sensory dysfunction in female mice. — PubMed · 2025 · Journal Article
Where this was looked for, and when
The latest collection walk and the accumulated shelf have different scopes. A zero applies only to that source query and its date window; older records may remain on the shelf. It does not mean no research exists.
| ClinicalTrials.gov | latest collection walk returned no records | asked on 2026-10-05 Collection window: 2026-09-16 – 2026-10-05 | matched in this collection walk 0 · accumulated records across collection walks 6 · still to fetch in this walk 0 | aim: every record matching this question |
|---|---|---|---|---|
| Crossref | asked, and it answered | asked on 2026-09-16 Collection window: all dates before the end date – 2026-09-16 | matched in this collection walk 1230843 · accumulated records across collection walks 50 | aim: a sample of the most relevant records. This source ranks a bag of words, so its own total is the size of the corpus that shares some of them, never a set still owed. |
| PubMed | asked, and it answered | asked on 2026-09-17 Collection window: all dates before the end date – 2026-09-17 | matched in this collection walk 3744 · accumulated records across collection walks 3744 · still to fetch in this walk 0 | aim: every record matching this question |
The question asked
- ClinicalTrials.gov
("neuroprotection" OR "secondary injury") - Crossref
spinal cord injury neuroprotection secondary injury - PubMed
("Spinal Cord Injuries"[MeSH Terms] OR "spinal cord injury"[Title/Abstract] OR "spinal cord injuries"[Title/Abstract] OR "spinal cord trauma"[Title/Abstract]) AND ("Neuroprotection"[MeSH Terms] OR "Neuroprotective Agents"[MeSH Terms] OR "neuroprotection"[Title/Abstract] OR "secondary injury"[Title/Abstract])