A subject this map covers
Neuroprotection
What belongs here
Attempts to stop the second, delayed wave of damage in the first hours and days.
What does not belong here, however close it looks
Restoring function lost months earlier is repair, not neuroprotection.
What has been looked at
Counted from what the sources catalogue, not from reading the work. It says how much exists and over what span of years — never what any of it found.
- Registered or indexed as work in people: 1169 records · 1978–2027
- Indexed as work in animals: 1885 records · 1977–2026
- Indexed as laboratory work: 80 records · 1996–2026
- The source has not said who or what was studied: 572 records · 1991–2026
- No matching published catalogue records are linked above. Human-review status must be checked on the evidence itself.
Published in this map
Catalogue records matching this subject. Publication here does not establish human review, measured results or effectiveness. Open a record to inspect its sources and evidence.
No published catalogue records match this subject yet.
This is a result within this map, not a claim that no research exists. The source records below can help you continue searching.
Found in the scientific sources, not yet checked
Titles and identifiers as the sources publish them. Nobody here has read these papers, and nothing on this shelf is a result, a recommendation or evidence that anything works. Each line opens the original.
3706 records
This grouping is the source's own cataloguing, not a reading of the paper. It says where a record was filed, not what it found.
Indexed as work in animals
- Single-Cell Sequencing Reveals the Optimal Time Window for Anti-Inflammatory Treatment in Spinal Cord Injury. — PubMed · 2023 · Journal Article
- [Neuroprotective effect and mechanism of cPLA2 inhibitor increases autophagic flux on spinal cord injury]. — PubMed · 2023 · English Abstract
- Pramipexole has a neuroprotective effect in spinal cord injury and upregulates D2 receptor expression in the injured spinal cord tissue in rats. — PubMed · 2023 · Journal Article
- Tofacitinib Promotes Functional Recovery after Spinal Cord Injury by Regulating Microglial Polarization via JAK/STAT Signaling Pathway. — PubMed · 2023 · Journal Article
- Rolipram-loaded PgP nanoparticle reduces secondary injury and enhances motor function recovery in a rat moderate contusion SCI model. — PubMed · 2023 · Journal Article
- Inhibition of Connexin43 Improves the Recovery of Spinal Cord Injury Against Ferroptosis via the SLC7A11/GPX4 Pathway. — PubMed · 2023 · Journal Article
- Neuroprotective Effects of Oxymatrine via Triggering Autophagy and Inhibiting Apoptosis Following Spinal Cord Injury in Rats. — PubMed · 2023 · Journal Article
- Carrier-Free Nanodrug Based on Co-Assembly of Methylprednisolone Dimer and Rutin for Combined Treatment of Spinal Cord Injury. — PubMed · 2023 · Journal Article
- Neuroprotective effects of quercetin on the cerebellum of zinc oxide nanoparticles (ZnoNps)-exposed rats. — PubMed · 2023 · Journal Article
- [Neuroprotective effect of tetramethylpyrazine on mice after spinal cord injury]. — PubMed · 2023 · English Abstract
- The neuro-protective role of telomerase via TERT/TERF-2 in the acute phase of spinal cord injury. — PubMed · 2023 · Journal Article
- Co-Administration of Resolvin D1 and Peripheral Nerve-Derived Stem Cell Spheroids as a Therapeutic Strategy in a Rat Model of Spinal Cord Injury. — PubMed · 2023 · Journal Article
- External magnetic field non-invasively stimulates spinal cord regeneration in rat via a magnetic-responsive aligned fibrin hydrogel. — PubMed · 2023 · Journal Article
- Sodium houttuyfonate exerts its neuroprotection effect by inhibiting the M1 microglia polarization in a TLR4/NF-κB signal pathway. — PubMed · 2023 · Journal Article
- Mesoporous polydopamine delivering 8-gingerol for the target and synergistic treatment to the spinal cord injury. — PubMed · 2023 · Journal Article
- The therapeutic mechanism of transcranial iTBS on nerve regeneration and functional recovery in rats with complete spinal cord transection. — PubMed · 2023 · Journal Article
- Acupuncture combined with moxibustion mitigates spinal cord injury-induced motor dysfunction in mice by NLRP3-IL-18 signaling pathway inhibition. — PubMed · 2023 · Journal Article
- Adipose-Derived Mesenchymal Stromal Cell Transplantation for Severe Spinal Cord Injury: Functional Improvement Supported by Angiogenesis and Neuroprotection. — PubMed · 2023 · Journal Article
- Hesperetin ameliorates spinal cord injury by inhibiting NLRP3 inflammasome activation and pyroptosis through enhancing Nrf2 signaling. — PubMed · 2023 · Journal Article
- Trace element, antioxidant and oxidant levels in spinal cord injury: different perspective on the effects of valproic acid. — PubMed · 2023 · Journal Article
- Short-chain fatty acids ameliorate spinal cord injury recovery by regulating the balance of regulatory T cells and effector IL-17(+) γδ T cells. — PubMed · 2023 · Journal Article
- An In Situ Assembled Trapping Gel Repairs Spinal Cord Injury by Capturing Glutamate and Free Calcium Ions. — PubMed · 2023 · Journal Article
- Inhibition of Neural Stem Cell Necroptosis Mediated by RIPK1/MLKL Promotes Functional Recovery After SCI. — PubMed · 2023 · Journal Article
- Morphofunctional Changes in the Spinal Cord of Rats after Contusion Injury with Local Delivery of Methylprednisolone in Combination with a Copolymer. — PubMed · 2023 · Journal Article
- PU.1 interaction with p50 promotes microglial-mediated inflammation in secondary spinal cord injury in SCI rats. — PubMed · 2023 · Journal Article
- The potential effects of polyunsaturated ω-3 fatty acids on spinal cord injury: A systematic review & meta-analysis of preclinical evidence. — PubMed · 2023 · Meta-Analysis
- The Limited Effects of Estradiol Administration Immediately after Spinal Cord Injury. — PubMed · 2023 · Multicenter Study
- Acute baclofen administration promotes functional recovery after spinal cord injury. — PubMed · 2023 · Journal Article
- HSPA1A ameliorated spinal cord injury in rats by inhibiting apoptosis to exert neuroprotective effects. — PubMed · 2023 · Journal Article
- Canine bone marrow peri-adipocyte cells could therapeutically benefit acute spinal cord injury through migration and secretion of hepatocyte growth factor to inflammatory milieu. — PubMed · 2023 · Journal Article
- Ca(2+) Regulates Autophagy Through CaMKKβ/AMPK/mTOR Signaling Pathway in Mechanical Spinal cord Injury: An in vitro Study. — PubMed · 2023 · Journal Article
- Delayed viral vector mediated delivery of neurotrophin-3 improves skilled hindlimb function and stability after thoracic contusion. — PubMed · 2023 · Journal Article
- Extracellular traps formation following cervical spinal cord injury. — PubMed · 2023 · Journal Article
- Neuroprotective Effects of Milrinone on Acute Traumatic Brain Injury. — PubMed · 2023 · Journal Article
- Perlecan Improves Blood Spinal Cord Barrier Repair Through the Integrin β1/ROCK/MLC Pathway After Spinal Cord Injury. — PubMed · 2023 · Journal Article
- Sitagliptin attenuates neuronal apoptosis via inhibiting the endoplasmic reticulum stress after acute spinal cord injury. — PubMed · 2023 · Journal Article
- TiO(2)-Nanowired Delivery of Chinese Extract of Ginkgo biloba EGb-761 and Bilobalide BN-52021 Enhanced Neuroprotective Effects of Cerebrolysin Following Spinal Cord Injury at Cold Environment. — PubMed · 2023 · Review
- Multifaceted Benefits of GDF11 Treatment in Spinal Cord Injury: In Vitro and In Vivo Studies. — PubMed · 2022 · Journal Article
- Restoring mitochondrial cardiolipin homeostasis reduces cell death and promotes recovery after spinal cord injury. — PubMed · 2022 · Journal Article
- Aberrant perineuronal nets alter spinal circuits, impair motor function, and increase plasticity. — PubMed · 2022 · Journal Article
- Chitosan-modified hollow manganese dioxide nanoparticles loaded with resveratrol for the treatment of spinal cord injury. — PubMed · 2022 · Journal Article
- Inflammatory Microenvironment-Responsive Nanomaterials Promote Spinal Cord Injury Repair by Targeting IRF5. — PubMed · 2022 · Journal Article
- Protective effects of hydrogen gas against spinal cord ischemia-reperfusion injury. — PubMed · 2022 · Journal Article
- Codelivery of minocycline hydrochloride and dextran sulfate via bionic liposomes for the treatment of spinal cord injury. — PubMed · 2022 · Journal Article
- LC-MS/MS-based arachidonic acid metabolomics in acute spinal cord injury reveals the upregulation of 5-LOX and COX-2 products. — PubMed · 2022 · Journal Article
- A decrease in the neuroprotective effects of acute spinal cord decompression according to injury severity: introducing the concept of a ceiling effect. — PubMed · 2022 · Journal Article
- Metformin Attenuates Ferroptosis and Promotes Functional Recovery of Spinal Cord Injury. — PubMed · 2022 · Journal Article
- Neuroprotective effects of lovastatin against traumatic spinal cord injury in rats. — PubMed · 2022 · Journal Article
- Omega-3 fatty acids in the treatment of spinal cord injury: untapped potential for therapeutic intervention? — PubMed · 2022 · Journal Article
- Proteomic characterization of spontaneously regrowing spinal cord following injury in the teleost fish Apteronotus leptorhynchus, a regeneration-competent vertebrate. — PubMed · 2022 · Journal Article
- The protective effects of nesfatin-1 in neurological dysfunction after spinal cord injury by inhibiting neuroinflammation. — PubMed · 2022 · Journal Article
- Aucubin promoted neuron functional recovery by suppressing inflammation and neuronal apoptosis in a spinal cord injury model. — PubMed · 2022 · Journal Article
- Traumatic brain injury alters dendritic cell differentiation and distribution in lymphoid and non-lymphoid organs. — PubMed · 2022 · Journal Article
- Ubiquitin ligase Triad1 promotes neurite outgrowth by inhibiting MDM2-mediated ubiquitination of the neuroprotective factor pleiotrophin. — PubMed · 2022 · Journal Article
- Melatonin Attenuates Spinal Cord Injury in Mice by Activating the Nrf2/ARE Signaling Pathway to Inhibit the NLRP3 Inflammasome. — PubMed · 2022 · Journal Article
- Amlodipine Improves Spinal Cord Injury Repair by Inhibiting Motoneuronal Apoptosis Through Autophagy Upregulation. — PubMed · 2022 · Journal Article
- Neuroprotective effect of the Nrf2/ARE/miRNA145-5p signaling pathway in the early phase of spinal cord injury. — PubMed · 2022 · Journal Article
- Neuroinduction and neuroprotection co-enhanced spinal cord injury repair based on IL-4@ZIF-8-loaded hyaluronan-collagen hydrogels with nano-aligned and viscoelastic cues. — PubMed · 2022 · Journal Article
- Grape Seed Proanthocyanidins Exert a Neuroprotective Effect by Regulating Microglial M1/M2 Polarisation in Rats with Spinal Cord Injury. — PubMed · 2022 · Journal Article
- Macrophages Treated with VEGF and PDGF Exert Paracrine Effects on Olfactory Ensheathing Cell Function. — PubMed · 2022 · Journal Article
Where this was looked for, and when
The latest collection walk and the accumulated shelf have different scopes. A zero applies only to that source query and its date window; older records may remain on the shelf. It does not mean no research exists.
| ClinicalTrials.gov | latest collection walk returned no records | asked on 2026-10-05 Collection window: 2026-09-16 – 2026-10-05 | matched in this collection walk 0 · accumulated records across collection walks 6 · still to fetch in this walk 0 | aim: every record matching this question |
|---|---|---|---|---|
| Crossref | asked, and it answered | asked on 2026-09-16 Collection window: all dates before the end date – 2026-09-16 | matched in this collection walk 1230843 · accumulated records across collection walks 50 | aim: a sample of the most relevant records. This source ranks a bag of words, so its own total is the size of the corpus that shares some of them, never a set still owed. |
| PubMed | asked, and it answered | asked on 2026-09-17 Collection window: all dates before the end date – 2026-09-17 | matched in this collection walk 3744 · accumulated records across collection walks 3744 · still to fetch in this walk 0 | aim: every record matching this question |
The question asked
- ClinicalTrials.gov
("neuroprotection" OR "secondary injury") - Crossref
spinal cord injury neuroprotection secondary injury - PubMed
("Spinal Cord Injuries"[MeSH Terms] OR "spinal cord injury"[Title/Abstract] OR "spinal cord injuries"[Title/Abstract] OR "spinal cord trauma"[Title/Abstract]) AND ("Neuroprotection"[MeSH Terms] OR "Neuroprotective Agents"[MeSH Terms] OR "neuroprotection"[Title/Abstract] OR "secondary injury"[Title/Abstract])