A subject this map covers
Neuroprotection
What belongs here
Attempts to stop the second, delayed wave of damage in the first hours and days.
What does not belong here, however close it looks
Restoring function lost months earlier is repair, not neuroprotection.
What has been looked at
Counted from what the sources catalogue, not from reading the work. It says how much exists and over what span of years — never what any of it found.
- Registered or indexed as work in people: 1169 records · 1978–2027
- Indexed as work in animals: 1885 records · 1977–2026
- Indexed as laboratory work: 80 records · 1996–2026
- The source has not said who or what was studied: 572 records · 1991–2026
- No matching published catalogue records are linked above. Human-review status must be checked on the evidence itself.
Published in this map
Catalogue records matching this subject. Publication here does not establish human review, measured results or effectiveness. Open a record to inspect its sources and evidence.
No published catalogue records match this subject yet.
This is a result within this map, not a claim that no research exists. The source records below can help you continue searching.
Found in the scientific sources, not yet checked
Titles and identifiers as the sources publish them. Nobody here has read these papers, and nothing on this shelf is a result, a recommendation or evidence that anything works. Each line opens the original.
3706 records
This grouping is the source's own cataloguing, not a reading of the paper. It says where a record was filed, not what it found.
Indexed as work in animals
- Advanced Age and Neurotrauma Diminish Glutathione and Impair Antioxidant Defense after Spinal Cord Injury. — PubMed · 2022 · Journal Article
- Immunoglobulin G Is Increased in the Injured Spinal Cord in a Sex- and Age-Dependent Manner. — PubMed · 2022 · Journal Article
- Magnesium Oxide/Poly(l-lactide-co-ε-caprolactone) Scaffolds Loaded with Neural Morphogens Promote Spinal Cord Repair through Targeting the Calcium Influx and Neuronal Differentiation of Neural Stem Cells. — PubMed · 2022 · Journal Article
- Traumatic Nervous System Injury. — PubMed · 2022 · Journal Article
- Meta-Analysis on the Effects of Electric Acupuncture on Neural Functional Recovery and Related Pathways of Rats after Spinal Cord Injury. — PubMed · 2022 · Journal Article The source marks this record as retracted.
- NPC transplantation rescues sci-driven cAMP/EPAC2 alterations, leading to neuroprotection and microglial modulation. — PubMed · 2022 · Journal Article
- WKYMVm/FPR2 Alleviates Spinal Cord Injury by Attenuating the Inflammatory Response of Microglia. — PubMed · 2022 · Journal Article
- Impairment of autophagy after spinal cord injury potentiates neuroinflammation and motor function deficit in mice. — PubMed · 2022 · Journal Article
- N-Acetylcysteine alleviates spinal cord injury in rats after early decompression surgery by regulating inflammation and apoptosis. — PubMed · 2022 · Journal Article
- Role of circadian rhythms in pathogenesis of acute CNS injuries: Insights from experimental studies. — PubMed · 2022 · Journal Article
- Fecal Microbiota Transplantation Exerts Neuroprotective Effects in a Mouse Spinal Cord Injury Model by Modulating the Microenvironment at the Lesion Site. — PubMed · 2022 · Journal Article
- BET protein inhibition promotes non-myeloid cell mediated neuroprotection after rodent spinal cord contusion. — PubMed · 2022 · Journal Article
- Dorsal horn neuronal sparing predicts the development of at-level mechanical allodynia following cervical spinal cord injury in mice. — PubMed · 2022 · Journal Article
- Wogonin inhibits inflammation and apoptosis through STAT3 signal pathway to promote the recovery of spinal cord injury. — PubMed · 2022 · Journal Article
- Peptide OM-LV20 promotes structural and functional recovery of spinal cord injury in rats. — PubMed · 2022 · Journal Article
- A Single Administration of Riluzole Applied Acutely After Spinal Cord Injury Attenuates Pro-inflammatory Activity and Improves Long-Term Functional Recovery in Rats. — PubMed · 2022 · Journal Article
- Heat-Shock Proteins Can Potentiate the Therapeutic Ability of Cryopreserved Mesenchymal Stem Cells for the Treatment of Acute Spinal Cord Injury in Dogs. — PubMed · 2022 · Journal Article
- Ischemic postconditioning reduces spinal cord ischemia-reperfusion injury through ATP-sensitive potassium channel. — PubMed · 2022 · Journal Article
- The Effects of the Combination of Mesenchymal Stromal Cells and Nanofiber-Hydrogel Composite on Repair of the Contused Spinal Cord. — PubMed · 2022 · Journal Article
- Metformin Protects against Spinal Cord Injury and Cell Pyroptosis via AMPK/NLRP3 Inflammasome Pathway. — PubMed · 2022 · Journal Article
- Ultrasound stimulation improves inflammatory resolution, neuroprotection, and functional recovery after spinal cord injury. — PubMed · 2022 · Journal Article
- Dexmedetomidine alleviates traumatic spinal cord injury in rats via inhibiting apoptosis induced by endoplasmic reticulum stress. — PubMed · 2022 · Journal Article
- E3 ubiquitin ligase Triad1 promotes neuronal apoptosis by regulating the p53-caspase3 pathway after spinal cord injury. — PubMed · 2022 · Journal Article
- Neuroprotective effect of aldose reductase knockout in a mouse model of spinal cord injury involves NF-κB pathway. — PubMed · 2022 · Journal Article
- Postcooling But Not Precooling Benefits Motor Recovery by Suppressing Cell Death After Surgical Spinal Cord Injury in Rats. — PubMed · 2022 · Journal Article
- [Experimental study of electric field stimulation combined with polyethylene glycol in the treatment of spinal cord injury in rats]. — PubMed · 2022 · Journal Article
- Premarin Reduces Neurodegeneration and Promotes Improvement of Function in an Animal Model of Spinal Cord Injury. — PubMed · 2022 · Journal Article
- Immune-responsive gene 1/itaconate activates nuclear factor erythroid 2-related factor 2 in microglia to protect against spinal cord injury in mice. — PubMed · 2022 · Journal Article
- Clemastine Enhances Myelination, Delays Axonal Loss and Promotes Functional Recovery in Spinal Cord Injury. — PubMed · 2022 · Journal Article
- Activation of glucagon-like peptide-1 receptor in microglia attenuates neuroinflammation-induced glial scarring via rescuing Arf and Rho GAP adapter protein 3 expressions after nerve injury. — PubMed · 2022 · Journal Article
- In vitro modulation of Schwann cell behavior by VEGF and PDGF in an inflammatory environment. — PubMed · 2022 · Journal Article
- Minocycline-Loaded Poly(α-Lipoic Acid)-Methylprednisolone Prodrug Nanoparticles for the Combined Anti-Inflammatory Treatment of Spinal Cord Injury. — PubMed · 2022 · Journal Article
- Can chlorogenic acid reduce oxidative stress and in an experimental spinal cord injury? — PubMed · 2022 · Journal Article
- Extracellular Vesicles in the Pathogenesis, Treatment, and Diagnosis of Spinal Cord Injury: A Mini-Review. — PubMed · 2022 · Journal Article
- Inhibition of CDK1 attenuates neuronal apoptosis and autophagy and confers neuroprotection after chronic spinal cord injury in vivo. — PubMed · 2022 · Journal Article
- Overview of the Neuroprotective Effects of the MAO-Inhibiting Antidepressant Phenelzine. — PubMed · 2022 · Journal Article
- Supplementation With Vitamin E, Zinc, Selenium, and Copper Re-Establishes T-Cell Function and Improves Motor Recovery in a Rat Model of Spinal Cord Injury. — PubMed · 2022 · Journal Article
- Inhibition of Bruton Tyrosine Kinase Reduces Neuroimmune Cascade and Promotes Recovery after Spinal Cord Injury. — PubMed · 2021 · Journal Article
- Inflammation after spinal cord injury: a review of the critical timeline of signaling cues and cellular infiltration. — PubMed · 2021 · Journal Article
- Long-Term Effects of Neural Precursor Cell Transplantation on Secondary Injury Processes and Functional Recovery after Severe Cervical Contusion-Compression Spinal Cord Injury. — PubMed · 2021 · Journal Article
- Anti-inflammatory and antioxidant effects of astaxanthin following spinal cord injury in a rat animal model. — PubMed · 2021 · Journal Article
- Novel optimized drug delivery systems for enhancing spinal cord injury repair in rats. — PubMed · 2021 · Journal Article
- Synergistic neuroprotective effects of hyperbaric oxygen and N-acetylcysteine against traumatic spinal cord injury in rat. — PubMed · 2021 · Journal Article
- Engineered extracellular vesicles derived from primary M2 macrophages with anti-inflammatory and neuroprotective properties for the treatment of spinal cord injury. — PubMed · 2021 · Journal Article
- Availability of neuregulin-1beta1 protects neurons in spinal cord injury and against glutamate toxicity through caspase dependent and independent mechanisms. — PubMed · 2021 · Journal Article
- Blocking the EGFR/p38/NF-κB signaling pathway alleviates disruption of BSCB and subsequent inflammation after spinal cord injury. — PubMed · 2021 · Journal Article
- Geniposide exerts protective effects on spinal cord injury in rats by inhibiting the IKKs/NF-κB signaling pathway. — PubMed · 2021 · Journal Article
- Astragalin Protects against Spinal Cord Ischemia Reperfusion Injury through Attenuating Oxidative Stress-Induced Necroptosis. — PubMed · 2021 · Journal Article The source marks this record as retracted.
- MCC950 Reduces Neuronal Apoptosis in Spinal Cord Injury in Mice. — PubMed · 2021 · Journal Article
- Resveratrol promotes axonal regeneration after spinal cord injury through activating Wnt/β-catenin signaling pathway. — PubMed · 2021 · Journal Article
- MicroRNA-7 promotes motor function recovery following spinal cord injury in mice. — PubMed · 2021 · Journal Article
- Efficacy of dental pulp-derived stem cells conditioned medium loaded in collagen hydrogel in spinal cord injury in rats: Stereological evidence. — PubMed · 2021 · Journal Article
- Resveratrol inhibits inflammation after spinal cord injury via SIRT-1/NF-κB signaling pathway. — PubMed · 2021 · Journal Article
- Tauroursodeoxycholic acid alleviates secondary injury in spinal cord injury mice by reducing oxidative stress, apoptosis, and inflammatory response. — PubMed · 2021 · Journal Article
- Nicotine Neurotoxicity Involves Low Wnt1 Signaling in Spinal Locomotor Networks of the Postnatal Rodent Spinal Cord. — PubMed · 2021 · Journal Article
- A rationally designed self-immolative linker enhances the synergism between a polymer-rock inhibitor conjugate and neural progenitor cells in the treatment of spinal cord injury. — PubMed · 2021 · Journal Article
- Assessment of the neuroprotective effects of (-)-epigallocatechin-3-gallate on spinal cord ischemia-reperfusion injury in rats. — PubMed · 2021 · Journal Article
- Dl-3-n-butylphthalide Attenuates Spinal Cord Injury via Regulation of MMPs and Junction Proteins in Mice. — PubMed · 2021 · Journal Article
- Effects of Gynostemma pentaphyllum on spinal cord motor neurons and microglial cells in vitro. — PubMed · 2021 · Journal Article
- MicroRNA-182 improves spinal cord injury in mice by modulating apoptosis and the inflammatory response via IKKβ/NF-κB. — PubMed · 2021 · Journal Article
Where this was looked for, and when
The latest collection walk and the accumulated shelf have different scopes. A zero applies only to that source query and its date window; older records may remain on the shelf. It does not mean no research exists.
| ClinicalTrials.gov | latest collection walk returned no records | asked on 2026-10-05 Collection window: 2026-09-16 – 2026-10-05 | matched in this collection walk 0 · accumulated records across collection walks 6 · still to fetch in this walk 0 | aim: every record matching this question |
|---|---|---|---|---|
| Crossref | asked, and it answered | asked on 2026-09-16 Collection window: all dates before the end date – 2026-09-16 | matched in this collection walk 1230843 · accumulated records across collection walks 50 | aim: a sample of the most relevant records. This source ranks a bag of words, so its own total is the size of the corpus that shares some of them, never a set still owed. |
| PubMed | asked, and it answered | asked on 2026-09-17 Collection window: all dates before the end date – 2026-09-17 | matched in this collection walk 3744 · accumulated records across collection walks 3744 · still to fetch in this walk 0 | aim: every record matching this question |
The question asked
- ClinicalTrials.gov
("neuroprotection" OR "secondary injury") - Crossref
spinal cord injury neuroprotection secondary injury - PubMed
("Spinal Cord Injuries"[MeSH Terms] OR "spinal cord injury"[Title/Abstract] OR "spinal cord injuries"[Title/Abstract] OR "spinal cord trauma"[Title/Abstract]) AND ("Neuroprotection"[MeSH Terms] OR "Neuroprotective Agents"[MeSH Terms] OR "neuroprotection"[Title/Abstract] OR "secondary injury"[Title/Abstract])