A subject this map covers
Neuroprotection
What belongs here
Attempts to stop the second, delayed wave of damage in the first hours and days.
What does not belong here, however close it looks
Restoring function lost months earlier is repair, not neuroprotection.
What has been looked at
Counted from what the sources catalogue, not from reading the work. It says how much exists and over what span of years — never what any of it found.
- Registered or indexed as work in people: 1169 records · 1978–2027
- Indexed as work in animals: 1885 records · 1977–2026
- Indexed as laboratory work: 80 records · 1996–2026
- The source has not said who or what was studied: 572 records · 1991–2026
- Nobody has yet checked any of this against its original for this map, so none of it is on the checked shelf.
Checked
Records a person has read against the original and published into this map. These carry measurements, evidence states and a place on the ladder.
Nobody has checked a record on this subject yet.
Checking is done by a person, one record at a time, and this subject has not reached the queue yet. The shelf below is what the sources hold in the meantime; it has not been read by anybody.
Found in the scientific sources, not yet checked
Titles and identifiers as the sources publish them. Nobody here has read these papers, and nothing on this shelf is a result, a recommendation or evidence that anything works. Each line opens the original.
3706 records
This grouping is the source's own cataloguing, not a reading of the paper. It says where a record was filed, not what it found.
Registered or indexed as work in people
- Pharmacological management of secondary spinal cord injury. — PubMed · 2021 · Journal Article
- Spinal cord regeneration: A brief overview of the present scenario and a sneak peek into the future. — PubMed · 2021 · Journal Article
- [Advances in olfactory ensheathing cells for the treatment of spinal cord injury]. — PubMed · 2021 · Journal Article
- GABAergic Mechanisms Can Redress the Tilted Balance between Excitation and Inhibition in Damaged Spinal Networks. — PubMed · 2021 · Journal Article
- Ketogenic regimens for acute neurotraumatic events. — PubMed · 2021 · Journal Article
- Elezanumab, a human anti-RGMa monoclonal antibody, promotes neuroprotection, neuroplasticity, and neurorecovery following a thoracic hemicompression spinal cord injury in non-human primates. — PubMed · 2021 · Journal Article
- Hypothermia for Acute Spinal Cord Injury. — PubMed · 2021 · Journal Article
- Neuroimmunological therapies for treating spinal cord injury: Evidence and future perspectives. — PubMed · 2021 · Journal Article
- Pathophysiology of Spinal Cord Injury. — PubMed · 2021 · Journal Article
- Prelude to the special issue on novel neurocircuit, cellular and molecular targets for developing functional rehabilitation therapies of neurotrauma. — PubMed · 2021 · Editorial
- Rationally Designed, Self-Assembling, Multifunctional Hydrogel Depot Repairs Severe Spinal Cord Injury. — PubMed · 2021 · Journal Article
- Systematic Review - Neuroprotection of ketosis in acute injury of the mammalian central nervous system: A meta-analysis. — PubMed · 2021 · Journal Article
- Sirtuins: Potential Therapeutic Targets for Defense against Oxidative Stress in Spinal Cord Injury. — PubMed · 2021 · Journal Article
- Acute spinal cord injury: Pathophysiology and pharmacological intervention (Review). — PubMed · 2021 · Journal Article
- Macrophage migration inhibitory factor as a therapeutic target after traumatic spinal cord injury: a systematic review. — PubMed · 2021 · Journal Article
- Updated Review: The Steroid Controversy for Management of Spinal Cord Injury. — PubMed · 2021 · Journal Article
- Human-Induced Neural and Mesenchymal Stem Cell Therapy Combined with a Curcumin Nanoconjugate as a Spinal Cord Injury Treatment. — PubMed · 2021 · Journal Article
- Blood-Spinal Cord Barrier in Spinal Cord Injury: A Review. — PubMed · 2021 · Journal Article
- Non-invasive approaches to functional recovery after spinal cord injury: Therapeutic targets and multimodal device interventions. — PubMed · 2021 · Journal Article
- Randomized trial of granulocyte colony-stimulating factor for spinal cord injury. — PubMed · 2021 · Clinical Trial, Phase Iii
- Antibiotics with therapeutic effects on spinal cord injury: a review. — PubMed · 2021 · Journal Article
- Comparison of Early Surgical Treatment With Conservative Treatment of Incomplete Cervical Spinal Cord Injury Without Major Fracture or Dislocation in Patients With Pre-existing Cervical Spinal Stenosis. — PubMed · 2021 · Journal Article
- MicroRNA-24-3p Inhibits Microglia Inflammation by Regulating MK2 Following Spinal Cord Injury. — PubMed · 2021 · Journal Article
- Systematic Review of Erythropoietin (EPO) for Neuroprotection in Human Studies. — PubMed · 2021 · Journal Article
- Exosomes derived from human placental mesenchymal stem cells enhanced the recovery of spinal cord injury by activating endogenous neurogenesis. — PubMed · 2021 · Journal Article
- Inhibition of astrocyte hemichannel improves recovery from spinal cord injury. — PubMed · 2021 · Journal Article
- Optimal Preclinical Conditions for Using Adult Human Multipotent Neural Cells in the Treatment of Spinal Cord Injury. — PubMed · 2021 · Journal Article
- Biomaterials and strategies for repairing spinal cord lesions. — PubMed · 2021 · Journal Article
- Progress in progestin-based therapies for neurological disorders. — PubMed · 2021 · Journal Article
- Amantadine: reappraisal of the timeless diamond-target updates and novel therapeutic potentials. — PubMed · 2021 · Journal Article
- Regulation of inflammatory cytokines for spinal cord injury recovery. — PubMed · 2021 · Journal Article
- Safety and efficacy of riluzole in patients undergoing decompressive surgery for degenerative cervical myelopathy (CSM-Protect): a multicentre, double-blind, placebo-controlled, randomised, phase 3 trial. — PubMed · 2021 · Clinical Trial, Phase Iii
- Targeting axon guidance cues for neural circuit repair after spinal cord injury. — PubMed · 2021 · Journal Article
- Traumatic Injuries to the Spinal Cord and Peripheral Nervous System. — PubMed · 2021 · Journal Article
- [Treatment of locked lower cervical fracture and dislocation with anterior cervical fusion and internal fixation combined with the release of interlocking facet through the Luschka joint and anterior lamina space]. — PubMed · 2021 · Journal Article
- Acute IL-1RA treatment suppresses the peripheral and central inflammatory response to spinal cord injury. — PubMed · 2021 · Journal Article
- Dental Pulp from Human Exfoliated Deciduous Teeth-derived Stromal Cells Demonstrated Neuronal Potential: In Vivo and In Vitro Studies. — PubMed · 2021 · Journal Article
- Neuromodulation as a basic platform for neuroprotection and repair after spinal cord injury. — PubMed · 2021 · Journal Article
- Role of astroglial toll-like receptors (TLRs) in central nervous system infections, injury and neurodegenerative diseases. — PubMed · 2021 · Journal Article
- The Pathogenesis of Neurotrauma Indicates Targets for Neuroprotective Therapies. — PubMed · 2021 · Journal Article
- Topical application of CNTF, GDNF and BDNF in combination attenuates blood-spinal cord barrier permeability, edema formation, hemeoxygenase-2 upregulation, and cord pathology. — PubMed · 2021 · Journal Article
- Feruloylated Oligosaccharides Alleviate Central Nervous Inflammation in Mice Following Spinal Cord Contusion. — PubMed · 2020 · Journal Article
- A New Therapeutic Strategy Targeting Protein Deacetylation for Spinal Cord Injury. — PubMed · 2020 · Journal Article
- The leading edge: Emerging neuroprotective and neuroregenerative cell-based therapies for spinal cord injury. — PubMed · 2020 · Journal Article
- Lycopene - A pleiotropic neuroprotective nutraceutical: Deciphering its therapeutic potentials in broad spectrum neurological disorders. — PubMed · 2020 · Journal Article
- Neurogenic Heterotopic Ossifications Develop Independently of Granulocyte Colony-Stimulating Factor and Neutrophils. — PubMed · 2020 · Journal Article
- Neuroprotective effects of Riluzole and Curcumin in human astrocytes and spinal cord white matter hypoxia. — PubMed · 2020 · Journal Article
- Treatment with 5-methoxytryptophan attenuates microglia-induced neuroinflammation in spinal cord trauma. — PubMed · 2020 · Journal Article
- Spinal Cord Injury: Pathophysiology, Multimolecular Interactions, and Underlying Recovery Mechanisms. — PubMed · 2020 · Journal Article
- Effects of rosmarinic acid on nervous system disorders: an updated review. — PubMed · 2020 · Journal Article
- Novel inhibitors of Rho-kinase mediated neuroinflammatory pathways and their potential application in recovery of injured spinal cord. — PubMed · 2020 · Journal Article
- Regenerative medicine for spinal cord injury: focus on stem cells and biomaterials. — PubMed · 2020 · Journal Article
- Human dental stem cells of the apical papilla associated to BDNF-loaded pharmacologically active microcarriers (PAMs) enhance locomotor function after spinal cord injury. — PubMed · 2020 · Journal Article
- Inhibition of phosphodiesterase IV enzyme improves locomotor and sensory complications of spinal cord injury via altering microglial activity: Introduction of Roflumilast as an alternative therapy. — PubMed · 2020 · Journal Article
- Reactive Astrogliosis: Implications in Spinal Cord Injury Progression and Therapy. — PubMed · 2020 · Journal Article
- Journal Club: High-dose methylprednisolone for acute traumatic spinal cord injury: A meta-analysis. — PubMed · 2020 · Journal Article
- Shock waves promote spinal cord repair via TLR3. — PubMed · 2020 · Journal Article
- Beneficial "Pharmaceutical Pleiotropy" of Gabapentinoids in Spinal Cord Injury: A Case for Refining Standard-of-Care. — PubMed · 2020 · Journal Article
- Emerging Therapeutic Strategies for Traumatic Spinal Cord Injury. — PubMed · 2020 · Journal Article
- Learning to promote recovery after spinal cord injury. — PubMed · 2020 · Journal Article
Where this was looked for, and when
The exact question each source was asked, the day it was asked, and what came back. A zero on this page is only honest if these are on it.
| ClinicalTrials.gov | asked, and it has nothing | asked on 2026-10-05 | the source found 0 · this programme has 6 · still to fetch 0 | aim: every record matching this question |
|---|---|---|---|---|
| Crossref | asked, and it answered | asked on 2026-09-16 | the source found 1230843 · this programme has 50 | aim: a sample of the most relevant records. This source ranks a bag of words, so its own total is the size of the corpus that shares some of them, never a set still owed. |
| PubMed | asked, and it answered | asked on 2026-09-17 | the source found 3744 · this programme has 3744 · still to fetch 0 | aim: every record matching this question |
The question asked
- ClinicalTrials.gov
("neuroprotection" OR "secondary injury") - Crossref
spinal cord injury neuroprotection secondary injury - PubMed
("Spinal Cord Injuries"[MeSH Terms] OR "spinal cord injury"[Title/Abstract] OR "spinal cord injuries"[Title/Abstract] OR "spinal cord trauma"[Title/Abstract]) AND ("Neuroprotection"[MeSH Terms] OR "Neuroprotective Agents"[MeSH Terms] OR "neuroprotection"[Title/Abstract] OR "secondary injury"[Title/Abstract])