A subject this map covers
Neuroprotection
What belongs here
Attempts to stop the second, delayed wave of damage in the first hours and days.
What does not belong here, however close it looks
Restoring function lost months earlier is repair, not neuroprotection.
What has been looked at
Counted from what the sources catalogue, not from reading the work. It says how much exists and over what span of years — never what any of it found.
- Registered or indexed as work in people: 1169 records · 1978–2027
- Indexed as work in animals: 1885 records · 1977–2026
- Indexed as laboratory work: 80 records · 1996–2026
- The source has not said who or what was studied: 572 records · 1991–2026
- Nobody has yet checked any of this against its original for this map, so none of it is on the checked shelf.
Checked
Records a person has read against the original and published into this map. These carry measurements, evidence states and a place on the ladder.
Nobody has checked a record on this subject yet.
Checking is done by a person, one record at a time, and this subject has not reached the queue yet. The shelf below is what the sources hold in the meantime; it has not been read by anybody.
Found in the scientific sources, not yet checked
Titles and identifiers as the sources publish them. Nobody here has read these papers, and nothing on this shelf is a result, a recommendation or evidence that anything works. Each line opens the original.
3706 records
This grouping is the source's own cataloguing, not a reading of the paper. It says where a record was filed, not what it found.
Registered or indexed as work in people
- Charcot Arthropathy of the Spine. — PubMed · 2022 · Journal Article
- Neuroprotective effect of geraniol on neurological disorders: a review article. — PubMed · 2022 · Journal Article
- Experimental Treatments for Spinal Cord Injury: A Systematic Review and Meta-Analysis. — PubMed · 2022 · Meta-Analysis
- The Proteostasis Network: A Global Therapeutic Target for Neuroprotection after Spinal Cord Injury. — PubMed · 2022 · Journal Article
- Biological and neurological activities of astaxanthin (Review). — PubMed · 2022 · Journal Article
- Delayed administration of elezanumab, a human anti-RGMa neutralizing monoclonal antibody, promotes recovery following cervical spinal cord injury. — PubMed · 2022 · Journal Article
- High-Throughput Screening Assay Identifies Berberine and Mubritinib as Neuroprotection Drugs for Spinal Cord Injury via Blood-Spinal Cord Barrier Protection. — PubMed · 2022 · Journal Article
- The Winnipeg Intraspinal Pressure Monitoring Study (WISP): A protocol for validation of fiberoptic pressure monitoring for acute traumatic spinal cord injury. — PubMed · 2022 · Journal Article
- Transplantation of Human Induced Pluripotent Stem Cell-Derived Neural Progenitor Cells Promotes Forelimb Functional Recovery after Cervical Spinal Cord Injury. — PubMed · 2022 · Journal Article
- The PI3K/AKT signalling pathway in inflammation, cell death and glial scar formation after traumatic spinal cord injury: Mechanisms and therapeutic opportunities. — PubMed · 2022 · Journal Article
- Spinal Stroke: Outcome Attenuation by Erythropoietin and Carbamylated Erythropoietin and Its Prediction by Sphingosine-1-Phosphate Serum Levels in Mice. — PubMed · 2022 · Journal Article
- Three-Dimensional-Cultured MSC-Derived Exosome-Hydrogel Hybrid Microneedle Array Patch for Spinal Cord Repair. — PubMed · 2022 · Journal Article
- A Bibliometric Analysis of Publications on Spinal Cord Injury Treatment With Glucocorticoids Using VOSviewer. — PubMed · 2022 · Journal Article
- Notoginsenoside R1 alleviates spinal cord injury by inhibiting oxidative stress, neuronal apoptosis, and inflammation via activating the nuclear factor erythroid 2 related factor 2/heme oxygenase-1 signaling pathway. — PubMed · 2022 · Journal Article
- Partial restoration of spinal cord neural continuity via vascular pedicle hemisected spinal cord transplantation using spinal cord fusion technique. — PubMed · 2022 · Journal Article
- Voluntary exercise ameliorates neuropathic pain by suppressing calcitonin gene-related peptide and ionized calcium-binding adapter molecule 1 overexpression in the lumbar dorsal horns in response to injury to the cervical spinal cord. — PubMed · 2022 · Journal Article
- Spinal Cord Injury Neuroprotection With Glyburide — ClinicalTrials.gov · 2022 · Interventional · Recruiting
- Dietary Restriction May Attenuate the Expression of Cell Death-Related Proteins in Rats with Acute Spinal Cord Injury. — PubMed · 2022 · Journal Article
- Functional hydrogels as therapeutic tools for spinal cord injury: New perspectives on immunopharmacological interventions. — PubMed · 2022 · Journal Article
- The Immunological Roles of Olfactory Ensheathing Cells in the Treatment of Spinal Cord Injury. — PubMed · 2022 · Journal Article
- The Role of miRNAs in Dexmedetomidine's Neuroprotective Effects against Brain Disorders. — PubMed · 2022 · Journal Article
- D-4F, an apolipoprotein A-I mimetic, promotes the clearance of myelin debris and the reduction of foamy macrophages after spinal cord injury. — PubMed · 2022 · Journal Article
- Hyperbaric Oxygen Therapy after Mid-Cervical Spinal Contusion Injury. — PubMed · 2022 · Journal Article
- Targeted delivery of acrolein scavenger hydralazine in spinal cord injury using folate-linker-drug conjugation. — PubMed · 2022 · Journal Article
- Tracking Antioxidant Status in Spinal Cord Injured Rodents: A Voltammetric Method Suited for Clinical Translation. — PubMed · 2022 · Journal Article
- Macrophage-based delivery of interleukin-13 improves functional and histopathological outcomes following spinal cord injury. — PubMed · 2022 · Journal Article
- Significant Therapeutic Effects of Adult Human Neural Stem Cells for Spinal Cord Injury Are Mediated by Monocyte Chemoattractant Protein-1 (MCP-1). — PubMed · 2022 · Journal Article
- 3D-Printed Polypyrrole Microneedle Arrays for Electronically Controlled Transdural Drug Release. — PubMed · 2022 · Journal Article
- Nutritional interventions for spinal cord injury: preclinical efficacy and molecular mechanisms. — PubMed · 2022 · Journal Article
- Neurotrophin-3 and neurotrophin-4: The unsung heroes that lies behind the meninges. — PubMed · 2022 · Journal Article
- Optimizing Nicorandil for Spinal Cord Protection in a Murine Model of Complex Aortic Intervention. — PubMed · 2022 · Journal Article
- The effect of extracorporeal shock wave therapy in acute traumatic spinal cord injury on motor and sensory function within 6 months post-injury: a study protocol for a two-arm three-stage adaptive, prospective, multi-center, randomized, blinded, placebo-controlled clinical trial. — PubMed · 2022 · Clinical Trial Protocol
- Reconnoitering the transformative journey of minocycline from an antibiotic to an antiepileptic drug. — PubMed · 2022 · Journal Article
- Cell transplantation and secretome based approaches in spinal cord injury regenerative medicine. — PubMed · 2022 · Journal Article
- Efficacy of Annona muricata (graviola) in experimental spinal cord injury: biochemical and histopathological analysis. — PubMed · 2022 · Journal Article
- Neuroinflammation after SCI: Current Insights and Therapeutic Potential of Intravenous Immunoglobulin. — PubMed · 2022 · Journal Article
- Role of Baclofen in Modulating Spasticity and Neuroprotection in Spinal Cord Injury. — PubMed · 2022 · Journal Article
- Spinal cord injury target-immunotherapy with TNF-α autoregulated and feedback-controlled human umbilical cord mesenchymal stem cell derived exosomes remodelled by CRISPR/Cas9 plasmid. — PubMed · 2022 · Journal Article
- Effects of Polyphenols on Oxidative Stress, Inflammation, and Interconnected Pathways during Spinal Cord Injury. — PubMed · 2022 · Journal Article
- Pott's disease (tuberculous spondylitis). — PubMed · 2022 · Case Reports
- Pros and Cons of Early and Very Early Surgery for Traumatic Central Cord Syndrome with Spinal Stenosis: Literature Review and Case Report. — PubMed · 2022 · Case Reports
- Regenerative Potential of Stem Cell-derived Extracellular Vesicles in Spinal Cord Injury (SCI). — PubMed · 2022 · Journal Article
- Therapeutic Efficacy of Human Mesenchymal Stem Cells With Different Delivery Route and Dosages in Rat Models of Spinal Cord Injury. — PubMed · 2022 · Journal Article
- Detection and Analysis of Perfusion Pressure through Measuring Oxygen Saturation and Requirement of Dural Incision Decompression after Laminectomy. — PubMed · 2021 · Journal Article The source marks this record as retracted.
- Facile fabrication of an erythropoietin-alginate/chitosan hydrogel and evaluation of its local therapeutic effects on spinal cord injury in rats. — PubMed · 2021 · Journal Article
- Protective Effects of Zinc on Spinal Cord Injury. — PubMed · 2021 · Journal Article
- 3D spheroids of human placenta-derived mesenchymal stem cells attenuate spinal cord injury in mice. — PubMed · 2021 · Journal Article
- Stem Cell Secretome for Spinal Cord Repair: Is It More than Just a Random Baseline Set of Factors? — PubMed · 2021 · Journal Article
- Sulfonylurea Receptor 1 in Central Nervous System Injury: An Updated Review. — PubMed · 2021 · Journal Article
- Antioxidant, anti-inflammatory and neuroprotective actions of resveratrol after experimental nervous system insults. Special focus on the molecular mechanisms involved. — PubMed · 2021 · Journal Article
- Corticospinal Motor Circuit Plasticity After Spinal Cord Injury: Harnessing Neuroplasticity to Improve Functional Outcomes. — PubMed · 2021 · Journal Article
- Inflammatory Response to Spinal Cord Injury and Its Treatment. — PubMed · 2021 · Journal Article
- Protective Effects of Estrogen via Nanoparticle Delivery to Attenuate Myelin Loss and Neuronal Death after Spinal Cord Injury. — PubMed · 2021 · Journal Article
- The combination of nanoscaffolds and stem cell transplantation: Paving a promising road for spinal cord injury regeneration. — PubMed · 2021 · Journal Article
- Bazedoxifene, a Selective Estrogen Receptor Modulator, Promotes Functional Recovery in a Spinal Cord Injury Rat Model. — PubMed · 2021 · Journal Article
- The Neuroprotective Role of Polydatin: Neuropharmacological Mechanisms, Molecular Targets, Therapeutic Potentials, and Clinical Perspective. — PubMed · 2021 · Journal Article
- A review of emerging neuroprotective and neuroregenerative therapies in traumatic spinal cord injury. — PubMed · 2021 · Journal Article
- Immunomodulation induced by central nervous system-related peptides as a therapeutic strategy for neurodegenerative disorders. — PubMed · 2021 · Journal Article
- Therapy of spinal cord injury by zinc modified gold nanoclusters via immune-suppressing strategies. — PubMed · 2021 · Journal Article
- Longitudinal Impact of Acute Spinal Cord Injury on Clinical Pharmacokinetics of Riluzole, a Potential Neuroprotective Agent. — PubMed · 2021 · Clinical Trial, Phase II
Where this was looked for, and when
The exact question each source was asked, the day it was asked, and what came back. A zero on this page is only honest if these are on it.
| ClinicalTrials.gov | asked, and it has nothing | asked on 2026-10-05 | the source found 0 · this programme has 6 · still to fetch 0 | aim: every record matching this question |
|---|---|---|---|---|
| Crossref | asked, and it answered | asked on 2026-09-16 | the source found 1230843 · this programme has 50 | aim: a sample of the most relevant records. This source ranks a bag of words, so its own total is the size of the corpus that shares some of them, never a set still owed. |
| PubMed | asked, and it answered | asked on 2026-09-17 | the source found 3744 · this programme has 3744 · still to fetch 0 | aim: every record matching this question |
The question asked
- ClinicalTrials.gov
("neuroprotection" OR "secondary injury") - Crossref
spinal cord injury neuroprotection secondary injury - PubMed
("Spinal Cord Injuries"[MeSH Terms] OR "spinal cord injury"[Title/Abstract] OR "spinal cord injuries"[Title/Abstract] OR "spinal cord trauma"[Title/Abstract]) AND ("Neuroprotection"[MeSH Terms] OR "Neuroprotective Agents"[MeSH Terms] OR "neuroprotection"[Title/Abstract] OR "secondary injury"[Title/Abstract])