A subject this map covers
Scar proteoglycan modulation
Part of: Glial scar and its remodelling
What belongs here
Acting on the scar’s inhibitory molecules or their receptors without enzymatic digestion.
What does not belong here, however close it looks
Enzymatic digestion is chondroitinase, a separate concept.
What has been looked at
Counted from what the sources catalogue, not from reading the work. It says how much exists and over what span of years — never what any of it found.
- Registered or indexed as work in people: 84 records · 2000–2025
- Indexed as work in animals: 244 records · 1997–2026
- Indexed as laboratory work: 23 records · 2004–2021
- The source has not said who or what was studied: 68 records · 1977–2026
- No clinical trial on this subject is registered for spinal cord injury.
- Nobody has yet checked any of this against its original for this map, so none of it is on the checked shelf.
Checked
Records a person has read against the original and published into this map. These carry measurements, evidence states and a place on the ladder.
Nobody has checked a record on this subject yet.
Checking is done by a person, one record at a time, and this subject has not reached the queue yet. The shelf below is what the sources hold in the meantime; it has not been read by anybody.
Found in the scientific sources, not yet checked
Titles and identifiers as the sources publish them. Nobody here has read these papers, and nothing on this shelf is a result, a recommendation or evidence that anything works. Each line opens the original.
419 records
This grouping is the source's own cataloguing, not a reading of the paper. It says where a record was filed, not what it found.
Indexed as work in animals
- Chondroitin 6-sulfate-binding peptides improve recovery in spinal cord-injured mice. — PubMed · 2021 · Journal Article
- Thermosensitive collagen/fibrinogen gels loaded with decorin suppress lesion site cavitation and promote functional recovery after spinal cord injury. — PubMed · 2021 · Journal Article
- Increasing toll-like receptor 2 on astrocytes induced by Schwann cell-derived exosomes promotes recovery by inhibiting CSPGs deposition after spinal cord injury. — PubMed · 2021 · Journal Article
- The Function of NG2/CSPG4-expressing Cells in the Rat Spinal Cord Injury: An Immunoelectron Microscopy Study. — PubMed · 2021 · Journal Article
- L-leucine promotes axonal outgrowth and regeneration via mTOR activation. — PubMed · 2021 · Journal Article
- Combined treatment with enteric neural stem cells and chondroitinase ABC reduces spinal cord lesion pathology. — PubMed · 2021 · Journal Article
- Optogenetic Modulation of Neural Progenitor Cells Improves Neuroregenerative Potential. — PubMed · 2020 · Journal Article
- [Effect and mechanism of glycyrrhizin on glial scar formation after spinal cord injury in rats]. — PubMed · 2020 · Journal Article
- Wnt-3a improves functional recovery through autophagy activation via inhibiting the mTOR signaling pathway after spinal cord injury. — PubMed · 2020 · Journal Article
- Enolase inhibition alters metabolic hormones and inflammatory factors to promote neuroprotection in spinal cord injury. — PubMed · 2020 · Journal Article
- Novel C1q receptor-mediated signaling controls neural stem cell behavior and neurorepair. — PubMed · 2020 · Journal Article
- Secretion of a mammalian chondroitinase ABC aids glial integration at PNS/CNS boundaries. — PubMed · 2020 · Journal Article
- L1 Cell Adhesion Molecule Overexpression Down Regulates Phosphacan and Up Regulates Structural Plasticity-Related Genes Rostral and Caudal to the Complete Spinal Cord Transection. — PubMed · 2020 · Journal Article
- Magnetic Field Promotes Migration of Schwann Cells with Chondroitinase ABC (ChABC)-Loaded Superparamagnetic Nanoparticles Across Astrocyte Boundary in vitro. — PubMed · 2020 · Journal Article
- Photobiomodulation Therapy Inhibit the Activation and Secretory of Astrocytes by Altering Macrophage Polarization. — PubMed · 2020 · Journal Article
- Spatiotemporal distribution of chondroitin sulfate proteoglycans after optic nerve injury in rodents. — PubMed · 2020 · Journal Article
- Epac2 Elevation Reverses Inhibition by Chondroitin Sulfate Proteoglycans In Vitro and Transforms Postlesion Inhibitory Environment to Promote Axonal Outgrowth in an Ex Vivo Model of Spinal Cord Injury. — PubMed · 2019 · Journal Article
- Upregulation of proteoglycans in the perilesion perimeter in ventral horns after spinal cord injury. — PubMed · 2019 · Journal Article
- Quantitative changes in perineuronal nets in development and posttraumatic condition. — PubMed · 2019 · Journal Article
- Regulation of Myelination by Exosome Associated Retinoic Acid Release from NG2-Positive Cells. — PubMed · 2019 · Journal Article
- Knockdown of Fidgetin Improves Regeneration of Injured Axons by a Microtubule-Based Mechanism. — PubMed · 2019 · Journal Article
- Local delivery of stabilized chondroitinase ABC degrades chondroitin sulfate proteoglycans in stroke-injured rat brains. — PubMed · 2019 · Journal Article
- Mouse mast cell protease 4 suppresses scar formation after traumatic spinal cord injury. — PubMed · 2019 · Journal Article
- Study on the pathological and biomedical characteristics of spinal cord injury by confocal Raman microspectral imaging. — PubMed · 2019 · Journal Article
- Analysis of reactive astrocytes and NG2 proteoglycan in ex vivo rat models of spinal cord injury. — PubMed · 2019 · Journal Article
- [Development of New Therapies for Neurodegenerative Diseases via Axonal Growth]. — PubMed · 2019 · Journal Article
- LAR and PTPσ receptors are negative regulators of oligodendrogenesis and oligodendrocyte integrity in spinal cord injury. — PubMed · 2019 · Journal Article
- Injury type-dependent differentiation of NG2 glia into heterogeneous astrocytes. — PubMed · 2018 · Journal Article
- Modulation of Receptor Protein Tyrosine Phosphatase Sigma Increases Chondroitin Sulfate Proteoglycan Degradation through Cathepsin B Secretion to Enhance Axon Outgrowth. — PubMed · 2018 · Journal Article
- Sox9 knockout mice have improved recovery following stroke. — PubMed · 2018 · Journal Article
- Perineuronal Nets in Spinal Motoneurones: Chondroitin Sulphate Proteoglycan around Alpha Motoneurones. — PubMed · 2018 · Journal Article
- Therapeutic time window for the effects of erythropoietin on astrogliosis and neurite outgrowth in an in vitro model of spinal cord injury. — PubMed · 2018 · Journal Article
- Proliferating NG2-Cell-Dependent Angiogenesis and Scar Formation Alter Axon Growth and Functional Recovery After Spinal Cord Injury in Mice. — PubMed · 2018 · Journal Article
- Label-Free Spectral Imaging Unveils Biochemical Mechanisms of Low-Level Laser Therapy on Spinal Cord Injury. — PubMed · 2018 · Journal Article
- Transplantation of canine olfactory ensheathing cells producing chondroitinase ABC promotes chondroitin sulphate proteoglycan digestion and axonal sprouting following spinal cord injury. — PubMed · 2017 · Journal Article
- Crocetin Potentiates Neurite Growth in Hippocampal Neurons and Facilitates Functional Recovery in Rats with Spinal Cord Injury. — PubMed · 2017 · Journal Article
- Intravenous immune-modifying nanoparticles as a therapy for spinal cord injury in mice. — PubMed · 2017 · Journal Article
- Local delivery of chondroitinase ABC with or without stromal cell-derived factor 1α promotes functional repair in the injured rat spinal cord. — PubMed · 2017 · Journal Article
- Combined treatment with chondroitinase ABC and treadmill rehabilitation for chronic severe spinal cord injury in adult rats. — PubMed · 2016 · Journal Article
- New Xymedon Analogues for Stimulation of Posttraumatic Regeneration of the Spinal Cord in Rats. — PubMed · 2016 · Journal Article
- Self-assembling peptides optimize the post-traumatic milieu and synergistically enhance the effects of neural stem cell therapy after cervical spinal cord injury. — PubMed · 2016 · Journal Article
- Delayed Exercise Is Ineffective at Reversing Aberrant Nociceptive Afferent Plasticity or Neuropathic Pain After Spinal Cord Injury in Rats. — PubMed · 2016 · Journal Article
- Expression of an Activated Integrin Promotes Long-Distance Sensory Axon Regeneration in the Spinal Cord. — PubMed · 2016 · Journal Article
- Absence of gliosis in a teleost model of spinal cord regeneration. — PubMed · 2016 · Journal Article
- Astrocyte scar formation aids central nervous system axon regeneration. — PubMed · 2016 · Journal Article
- Intrathecal decompression versus epidural decompression in the treatment of severe spinal cord injury in rat model: a randomized, controlled preclinical research. — PubMed · 2016 · Comparative Study
- Guiding migration of transplanted glial progenitor cells in the injured spinal cord. — PubMed · 2016 · Journal Article
- Inhibition of CRMP2 phosphorylation repairs CNS by regulating neurotrophic and inhibitory responses. — PubMed · 2016 · Journal Article
- Beneficial effects of local profound hypothermia and the possible mechanism after experimental spinal cord injury in rats. — PubMed · 2016 · Journal Article
- Protein phosphatase 2A (PP2A) activation promotes axonal growth and recovery in the CNS. — PubMed · 2015 · Journal Article
- Combination therapy of stem cell derived neural progenitors and drug delivery of anti-inhibitory molecules for spinal cord injury. — PubMed · 2015 · Journal Article
- Delivery of Alginate Scaffold Releasing Two Trophic Factors for Spinal Cord Injury Repair. — PubMed · 2015 · Journal Article
- Neuroprotective Effects of Direct Intrathecal Administration of Granulocyte Colony-Stimulating Factor in Rats with Spinal Cord Injury. — PubMed · 2015 · Journal Article
- Chondroitin Sulfate Proteoglycans Negatively Modulate Spinal Cord Neural Precursor Cells by Signaling Through LAR and RPTPσ and Modulation of the Rho/ROCK Pathway. — PubMed · 2015 · Journal Article
- Histone acetylation inhibitors promote axon growth in adult dorsal root ganglia neurons. — PubMed · 2015 · Journal Article
- Characterization and therapeutic evaluation of a Nestin⁺ CNP⁺ NG2⁺ cell population on mouse spinal cord injury. — PubMed · 2015 · Journal Article
- Increased migration of olfactory ensheathing cells secreting the Nogo receptor ectodomain over inhibitory substrates and lesioned spinal cord. — PubMed · 2015 · Journal Article
- Positively Charged Oligo[Poly(Ethylene Glycol) Fumarate] Scaffold Implantation Results in a Permissive Lesion Environment after Spinal Cord Injury in Rat. — PubMed · 2015 · Journal Article
- The effect of spinal cord injury on the neurochemical properties of vagal sensory neurons. — PubMed · 2015 · Journal Article
- Spinal Glia Division Contributes to Conditioning Lesion-Induced Axon Regeneration Into the Injured Spinal Cord: Potential Role of Cyclic AMP-Induced Tissue Inhibitor of Metalloproteinase-1. — PubMed · 2015 · Journal Article
Where this was looked for, and when
The exact question each source was asked, the day it was asked, and what came back. A zero on this page is only honest if these are on it.
| ClinicalTrials.gov | asked, and it has nothing | asked on 2026-10-05 | the source found 0 · this programme has 0 · still to fetch 0 | aim: every record matching this question |
|---|---|---|---|---|
| Crossref | asked, and it answered | asked on 2026-09-16 | the source found 1527414 · this programme has 50 | aim: a sample of the most relevant records. This source ranks a bag of words, so its own total is the size of the corpus that shares some of them, never a set still owed. |
| PubMed | asked, and it answered | asked on 2026-09-17 | the source found 404 · this programme has 404 · still to fetch 0 | aim: every record matching this question |
The question asked
- ClinicalTrials.gov
("chondroitin sulfate proteoglycan" OR "CSPG receptor" OR "PTPsigma peptide") - Crossref
spinal cord injury chondroitin sulfate proteoglycan CSPG receptor - PubMed
("Spinal Cord Injuries"[MeSH Terms] OR "spinal cord injury"[Title/Abstract] OR "spinal cord injuries"[Title/Abstract] OR "spinal cord trauma"[Title/Abstract]) AND ("Chondroitin Sulfate Proteoglycans"[MeSH Terms] OR "chondroitin sulfate proteoglycan"[Title/Abstract] OR "CSPG receptor"[Title/Abstract] OR "PTPsigma peptide"[Title/Abstract])