A subject this map covers
Viral vector delivery
Part of: Gene therapy
What belongs here
Gene delivery by viral vector to the cord or to the neurons that reach it.
What does not belong here, however close it looks
Non-viral delivery — nanoparticles, electroporation — has its own concepts.
What has been looked at
Counted from what the sources catalogue, not from reading the work. It says how much exists and over what span of years — never what any of it found.
- Registered or indexed as work in people: 92 records · 1995–2026
- Indexed as work in animals: 246 records · 1998–2026
- Indexed as laboratory work: 13 records · 1997–2021
- The source has not said who or what was studied: 68 records · 1996–2026
- No clinical trial on this subject is registered for spinal cord injury.
- Nobody has yet checked any of this against its original for this map, so none of it is on the checked shelf.
Checked
Records a person has read against the original and published into this map. These carry measurements, evidence states and a place on the ladder.
Nobody has checked a record on this subject yet.
Checking is done by a person, one record at a time, and this subject has not reached the queue yet. The shelf below is what the sources hold in the meantime; it has not been read by anybody.
Found in the scientific sources, not yet checked
Titles and identifiers as the sources publish them. Nobody here has read these papers, and nothing on this shelf is a result, a recommendation or evidence that anything works. Each line opens the original.
419 records
This grouping is the source's own cataloguing, not a reading of the paper. It says where a record was filed, not what it found.
Indexed as work in animals
- AAV Vector Mediated Delivery of NG2 Function Neutralizing Antibody and Neurotrophin NT-3 Improves Synaptic Transmission, Locomotion, and Urinary Tract Function after Spinal Cord Contusion Injury in Adult Rats. — PubMed · 2023 · Journal Article
- USP1/UAF1-Stabilized METTL3 Promotes Reactive Astrogliosis and Improves Functional Recovery after Spinal Cord Injury through m(6)A Modification of YAP1 mRNA. — PubMed · 2023 · Journal Article
- The LncRNA AK018453 regulates TRAP1/Smad signaling in IL-17-activated astrocytes: A potential role in EAE pathogenesis. — PubMed · 2022 · Journal Article
- Development and Assessment of Herpes Simplex Virus Type 1 (HSV-1) Amplicon Vectors with Sensory Neuron-Selective Promoters. — PubMed · 2022 · Journal Article
- Brain-wide analysis of the supraspinal connectome reveals anatomical correlates to functional recovery after spinal injury. — PubMed · 2022 · Journal Article
- Sustained developmental endothelial locus-1 overexpression promotes spinal cord injury recovery in mice through the SIRT1/SERCA2 signaling pathway. — PubMed · 2022 · Journal Article
- hUC-MSC-mediated recovery of subacute spinal cord injury through enhancing the pivotal subunits β3 and γ2 of the GABA(A) receptor. — PubMed · 2022 · Journal Article
- Electroacupuncture Inhibits NLRP3 Activation by Regulating CMPK2 After Spinal Cord Injury. — PubMed · 2022 · Journal Article
- Cotransplantation with RADA16-PRG-Self-Assembled Nanopeptide Scaffolds, Bone Mesenchymal Stem Cells and Brain-Derived Neurotrophic Factor-Adeno-Associated Virus Promote Functional Repair After Acute Spinal Cord Injury in Rats. — PubMed · 2022 · Journal Article
- Microglial deactivation by adeno-associated virus expressing small-hairpin GCH1 has protective effects against neuropathic pain development in a spinothalamic tract-lesion model. — PubMed · 2022 · Journal Article
- MicroRNA-7 promotes motor function recovery following spinal cord injury in mice. — PubMed · 2021 · Journal Article
- Overexpression of bone morphogenetic protein 7 reduces oligodendrocytes loss and promotes functional recovery after spinal cord injury. — PubMed · 2021 · Journal Article
- Lentiviral Vectors Delivered with Biomaterials as Therapeutics for Spinal Cord Injury. — PubMed · 2021 · Journal Article
- Gsx1 promotes locomotor functional recovery after spinal cord injury. — PubMed · 2021 · Journal Article
- Deubiquitinase USP18 regulates reactive astrogliosis by stabilizing SOX9. — PubMed · 2021 · Journal Article
- Effects of Wnt5a overexpression in spinal cord injury. — PubMed · 2021 · Journal Article
- Conditional RAC1 knockout in motor neurons restores H-reflex rate-dependent depression after spinal cord injury. — PubMed · 2021 · Journal Article
- Engineering polysialic acid on Schwann cells using polysialyltransferase gene transfer or purified enzyme exposure for spinal cord injury transplantation. — PubMed · 2021 · Journal Article
- AAV2-mediated and hypoxia response element-directed expression of bFGF in neural stem cells showed therapeutic effects on spinal cord injury in rats. — PubMed · 2021 · Journal Article
- AAV-mediated inhibition of ULK1 promotes axonal regeneration in the central nervous system in vitro and in vivo. — PubMed · 2021 · Journal Article
- Improving hindlimb locomotor function by Non-invasive AAV-mediated manipulations of propriospinal neurons in mice with complete spinal cord injury. — PubMed · 2021 · Journal Article
- Optimization of adeno-associated viral vector-mediated transduction of the corticospinal tract: comparison of four promoters. — PubMed · 2021 · Journal Article
- A micro-LED implant and technique for optogenetic stimulation of the rat spinal cord. — PubMed · 2021 · Journal Article
- Intravenous transplantation of olfactory ensheathing cells reduces neuroinflammation after spinal cord injury via interleukin-1 receptor antagonist. — PubMed · 2021 · Journal Article
- Astrocytic reprogramming combined with rehabilitation strategy improves recovery from spinal cord injury. — PubMed · 2020 · Journal Article
- The Gigantocellular Reticular Nucleus Plays a Significant Role in Locomotor Recovery after Incomplete Spinal Cord Injury. — PubMed · 2020 · Journal Article
- Upregulating Lin28a Promotes Axon Regeneration in Adult Mice with Optic Nerve and Spinal Cord Injury. — PubMed · 2020 · Journal Article
- Nuclear Heme Oxidase-1 Inhibits Endoplasmic Reticulum Stress-Mediated Apoptosis after Spinal Cord Injury. — PubMed · 2020 · Journal Article
- Astrocyte-selective AAV-ADAMTS4 gene therapy combined with hindlimb rehabilitation promotes functional recovery after spinal cord injury. — PubMed · 2020 · Journal Article
- Repairing and Analgesic Effects of Umbilical Cord Mesenchymal Stem Cell Transplantation in Mice with Spinal Cord Injury. — PubMed · 2020 · Journal Article
- Profilin 1 delivery tunes cytoskeletal dynamics toward CNS axon regeneration. — PubMed · 2020 · Journal Article
- Protein Tyrosine Phosphatase σ Inhibitory Peptide Promotes Recovery of Diaphragm Function and Sprouting of Bulbospinal Respiratory Axons after Cervical Spinal Cord Injury. — PubMed · 2020 · Journal Article
- The protective effort of GPCR kinase 2-interacting protein-1 in neurons via promoting Beclin1-Parkin induced mitophagy at the early stage of spinal cord ischemia-reperfusion injury. — PubMed · 2020 · Journal Article
- Adeno-associated virus packaged TRPC5 gene therapy alleviated spinal cord ischemic reperfusion injury in rats. — PubMed · 2020 · Journal Article
- Transplantation of sh-miR-199a-5p-Modified Olfactory Ensheathing Cells Promotes the Functional Recovery in Rats with Contusive Spinal Cord Injury. — PubMed · 2020 · Journal Article
- Lentivirus-mediated downregulation of α-synuclein reduces neuroinflammation and promotes functional recovery in rats with spinal cord injury. — PubMed · 2019 · Journal Article
- AAV2-BDNF promotes respiratory axon plasticity and recovery of diaphragm function following spinal cord injury. — PubMed · 2019 · Journal Article
- Transcriptomic analysis of α-synuclein knockdown after T3 spinal cord injury in rats. — PubMed · 2019 · Journal Article
- Adenovirus vector‑mediated in vivo gene transfer of nuclear factor erythroid‑2p45‑related factor 2 promotes functional recovery following spinal cord contusion. — PubMed · 2019 · Journal Article
- BMP4/Smad1 Signalling Promotes Spinal Dorsal Column Axon Regeneration and Functional Recovery After Injury. — PubMed · 2019 · Journal Article
- Regulatory effect of neuroglobin in the recovery of spinal cord injury. — PubMed · 2019 · Journal Article
- APC-Cdh1 Inhibits the Proliferation and Activation of Oligodendrocyte Precursor Cells after Mechanical Stretch Injury. — PubMed · 2019 · Journal Article
- Expression of miR-210 mediated by adeno-associated virus performed neuroprotective effects on a rat model of acute spinal cord injury. — PubMed · 2019 · Journal Article
- Intramuscular Injection of Adenoassociated Virus Encoding Human Neurotrophic Factor 3 and Exercise Intervention Contribute to Reduce Spasms after Spinal Cord Injury. — PubMed · 2019 · Journal Article
- Promoting Axon Regeneration in Adult CNS by Targeting Liver Kinase B1. — PubMed · 2019 · Journal Article
- Combinatorial lentiviral gene delivery of pro-oligodendrogenic factors for improving myelination of regenerating axons after spinal cord injury. — PubMed · 2019 · Journal Article
- Upregulation of UBAP2L in Bone Marrow Mesenchymal Stem Cells Promotes Functional Recovery in Rats with Spinal Cord Injury. — PubMed · 2018 · Journal Article
- Reducing inflammation through delivery of lentivirus encoding for anti-inflammatory cytokines attenuates neuropathic pain after spinal cord injury. — PubMed · 2018 · Journal Article
- Lentivirus-Mediated Overexpression of miR-29a Promotes Axonal Regeneration and Functional Recovery in Experimental Spinal Cord Injury via PI3K/Akt/mTOR Pathway. — PubMed · 2018 · Journal Article
- LncRNA ZNF667-AS1 inhibits inflammatory response and promotes recovery of spinal cord injury via suppressing JAK-STAT pathway. — PubMed · 2018 · Journal Article
- Silencing of PHLPP1 promotes neuronal apoptosis and inhibits functional recovery after spinal cord injury in mice. — PubMed · 2018 · Journal Article
- Remodeling of lumbar motor circuitry remote to a thoracic spinal cord injury promotes locomotor recovery. — PubMed · 2018 · Journal Article
- Cortical AAV-CNTF Gene Therapy Combined with Intraspinal Mesenchymal Precursor Cell Transplantation Promotes Functional and Morphological Outcomes after Spinal Cord Injury in Adult Rats. — PubMed · 2018 · Journal Article
- Optogenetic surface stimulation of the rat cervical spinal cord. — PubMed · 2018 · Journal Article
- MST1 Suppression Reduces Early Brain Injury by Inhibiting the NF-κB/MMP-9 Pathway after Subarachnoid Hemorrhage in Mice. — PubMed · 2018 · Journal Article
- Cell-type specific expression of constitutively-active Rheb promotes regeneration of bulbospinal respiratory axons following cervical SCI. — PubMed · 2018 · Journal Article
- FGF1 improves functional recovery through inducing PRDX1 to regulate autophagy and anti-ROS after spinal cord injury. — PubMed · 2018 · Journal Article
- Lentiviral vector delivery of short hairpin RNA to NgR1 promotes nerve regeneration and locomotor recovery in injured rat spinal cord. — PubMed · 2018 · Journal Article
- Adenovirus-delivered GFP-HO-1C[INCREMENT]23 attenuates blood-spinal cord barrier permeability after rat spinal cord contusion. — PubMed · 2018 · Journal Article
- Lentivirus Mediating FGF13 Enhances Axon Regeneration after Spinal Cord Injury by Stabilizing Microtubule and Improving Mitochondrial Function. — PubMed · 2018 · Journal Article
Where this was looked for, and when
The exact question each source was asked, the day it was asked, and what came back. A zero on this page is only honest if these are on it.
| ClinicalTrials.gov | asked, and it has nothing | asked on 2026-10-05 | the source found 0 · this programme has 0 · still to fetch 0 | aim: every record matching this question |
|---|---|---|---|---|
| Crossref | asked, and it answered | asked on 2026-09-17 | the source found 2898038 · this programme has 50 | aim: a sample of the most relevant records. This source ranks a bag of words, so its own total is the size of the corpus that shares some of them, never a set still owed. |
| PubMed | asked, and it answered | asked on 2026-09-17 | the source found 393 · this programme has 393 · still to fetch 0 | aim: every record matching this question |
The question asked
- ClinicalTrials.gov
("adeno-associated virus" OR "AAV vector" OR "lentiviral vector") - Crossref
spinal cord injury adeno-associated virus AAV vector - PubMed
("Spinal Cord Injuries"[MeSH Terms] OR "spinal cord injury"[Title/Abstract] OR "spinal cord injuries"[Title/Abstract] OR "spinal cord trauma"[Title/Abstract]) AND ("Dependovirus"[MeSH Terms] OR "Genetic Vectors"[MeSH Terms] OR "adeno-associated virus"[Title/Abstract] OR "AAV vector"[Title/Abstract] OR "lentiviral vector"[Title/Abstract])