A subject this map covers
Viral vector delivery
Part of: Gene therapy
What belongs here
Gene delivery by viral vector to the cord or to the neurons that reach it.
What does not belong here, however close it looks
Non-viral delivery — nanoparticles, electroporation — has its own concepts.
What has been looked at
Counted from what the sources catalogue, not from reading the work. It says how much exists and over what span of years — never what any of it found.
- Registered or indexed as work in people: 92 records · 1995–2026
- Indexed as work in animals: 246 records · 1998–2026
- Indexed as laboratory work: 13 records · 1997–2021
- The source has not said who or what was studied: 68 records · 1996–2026
- No clinical trial on this subject is registered for spinal cord injury.
- Nobody has yet checked any of this against its original for this map, so none of it is on the checked shelf.
Checked
Records a person has read against the original and published into this map. These carry measurements, evidence states and a place on the ladder.
Nobody has checked a record on this subject yet.
Checking is done by a person, one record at a time, and this subject has not reached the queue yet. The shelf below is what the sources hold in the meantime; it has not been read by anybody.
Found in the scientific sources, not yet checked
Titles and identifiers as the sources publish them. Nobody here has read these papers, and nothing on this shelf is a result, a recommendation or evidence that anything works. Each line opens the original.
419 records
This grouping is the source's own cataloguing, not a reading of the paper. It says where a record was filed, not what it found.
Indexed as work in animals
- miR-136-5p Regulates the Inflammatory Response by Targeting the IKKβ/NF-κB/A20 Pathway After Spinal Cord Injury. — PubMed · 2018 · Journal Article
- Combining Constitutively Active Rheb Expression and Chondroitinase Promotes Functional Axonal Regeneration after Cervical Spinal Cord Injury. — PubMed · 2017 · Journal Article
- Morphological changes in different populations of bladder afferent neurons detected by herpes simplex virus (HSV) vectors with cell-type-specific promoters in mice with spinal cord injury. — PubMed · 2017 · Journal Article
- Regulated viral BDNF delivery in combination with Schwann cells promotes axonal regeneration through capillary alginate hydrogels after spinal cord injury. — PubMed · 2017 · Journal Article
- Lentivirus-mediated inhibition of AQP4 accelerates motor function recovery associated with NGF in spinal cord contusion rats. — PubMed · 2017 · Journal Article
- Subpial Adeno-associated Virus 9 (AAV9) Vector Delivery in Adult Mice. — PubMed · 2017 · Journal Article
- A fusion of minicircle DNA and nanoparticle delivery technologies facilitates therapeutic genetic engineering of autologous canine olfactory mucosal cells. — PubMed · 2017 · Journal Article
- Effect of urethral wall injection of replication-defective herpes simplex virus-mediated gene transfer of kynurenine aminotransferase on urethral pressure in spinal cord-injured rats. — PubMed · 2017 · Evaluation Study
- Heme Oxygenase-1 Inhibits Neuronal Apoptosis in Spinal Cord Injury through Down-Regulation of Cdc42-MLK3-MKK7-JNK3 Axis. — PubMed · 2017 · Journal Article
- Contribution of propriospinal neurons to recovery of hand dexterity after corticospinal tract lesions in monkeys. — PubMed · 2017 · Journal Article
- Molecular Mechanism of MiR-136-5p Targeting NF-κB/A20 in the IL-17-Mediated Inflammatory Response after Spinal Cord Injury. — PubMed · 2017 · Journal Article
- Lentiviral Vector-Mediated p27(kip1) Expression Facilitates Recovery After Spinal Cord Injury. — PubMed · 2016 · Journal Article
- Combination of grafted Schwann cells and lentiviral-mediated prevention of glial scar formation improve recovery of spinal cord injured rats. — PubMed · 2016 · Journal Article
- Lipopolysaccharide-induced preconditioning protects against traumatic spinal cord injury by upregulating Nrf2 expression in rats. — PubMed · 2016 · Journal Article
- Axonal Localization of Integrins in the CNS Is Neuronal Type and Age Dependent. — PubMed · 2016 · Journal Article
- Lentivirus-mediated PGC-1α overexpression protects against traumatic spinal cord injury in rats. — PubMed · 2016 · Journal Article
- Expression of an Activated Integrin Promotes Long-Distance Sensory Axon Regeneration in the Spinal Cord. — PubMed · 2016 · Journal Article
- Migration of Adipose-derived Mesenchymal Stem Cells Stably Expressing Chondroitinase ABC In vitro. — PubMed · 2016 · Journal Article
- Exogenous Neuritin Promotes Nerve Regeneration After Acute Spinal Cord Injury in Rats. — PubMed · 2016 · Journal Article
- Myelin Basic Protein Cleaves Cell Adhesion Molecule L1 and Improves Regeneration After Injury. — PubMed · 2016 · Journal Article
- Optogenetic Interrogation of Functional Synapse Formation by Corticospinal Tract Axons in the Injured Spinal Cord. — PubMed · 2016 · Journal Article
- Adeno associated viral-mediated intraosseous labeling of bone marrow derived cells for CNS tracking. — PubMed · 2016 · Journal Article
- Re-Establishment of Cortical Motor Output Maps and Spontaneous Functional Recovery via Spared Dorsolaterally Projecting Corticospinal Neurons after Dorsal Column Spinal Cord Injury in Adult Mice. — PubMed · 2016 · Journal Article
- GLT1 overexpression reverses established neuropathic pain-related behavior and attenuates chronic dorsal horn neuron activation following cervical spinal cord injury. — PubMed · 2016 · Journal Article
- Targeted Inhibition of Leucine-Rich Repeat and Immunoglobulin Domain-Containing Protein 1 in Transplanted Neural Stem Cells Promotes Neuronal Differentiation and Functional Recovery in Rats Subjected to Spinal Cord Injury. — PubMed · 2016 · Journal Article
- Heme oxygenase-1 promotes neuron survival through down-regulation of neuronal NLRP1 expression after spinal cord injury. — PubMed · 2016 · Journal Article
- TrkB gene therapy by adeno-associated virus enhances recovery after cervical spinal cord injury. — PubMed · 2016 · Journal Article
- Spinal electro-magnetic stimulation combined with transgene delivery of neurotrophin NT-3 and exercise: novel combination therapy for spinal contusion injury. — PubMed · 2015 · Journal Article
- ICAM1 depletion reduces spinal metastasis formation in vivo and improves neurological outcome. — PubMed · 2015 · Journal Article
- Local Injection of Lenti-BDNF at the Lesion Site Promotes M2 Macrophage Polarization and Inhibits Inflammatory Response After Spinal Cord Injury in Mice. — PubMed · 2015 · Journal Article
- Development of a novel imaging system for cell therapy in the brain. — PubMed · 2015 · Journal Article
- AAV-mediated expression of BAG1 and ROCK2-shRNA promote neuronal survival and axonal sprouting in a rat model of rubrospinal tract injury. — PubMed · 2015 · Journal Article
- Gene delivery to the spinal cord using MRI-guided focused ultrasound. — PubMed · 2015 · Journal Article
- MASH1/Ascl1a leads to GAP43 expression and axon regeneration in the adult CNS. — PubMed · 2015 · Journal Article
- Transplantation of glial progenitors that overexpress glutamate transporter GLT1 preserves diaphragm function following cervical SCI. — PubMed · 2015 · Journal Article
- Lentivirus-mediated inhibition of tumour necrosis factor-α improves motor function associated with PRDX6 in spinal cord contusion rats. — PubMed · 2015 · Journal Article
- Prohibitin 1 gene delivery promotes functional recovery in rats with spinal cord injury. — PubMed · 2015 · Journal Article
- Lentiviral-mediated silencing of glial fibrillary acidic protein and vimentin promotes anatomical plasticity and functional recovery after spinal cord injury. — PubMed · 2015 · Journal Article
- Stable transfection into rat bone marrow mesenchymal stem cells by lentivirus-mediated NT-3. — PubMed · 2015 · Journal Article
- Detection of optogenetic stimulation in somatosensory cortex by non-human primates--towards artificial tactile sensation. — PubMed · 2014 · Journal Article
- Transduction efficiency of neurons and glial cells by AAV-1, -5, -9, -rh10 and -hu11 serotypes in rat spinal cord following contusion injury. — PubMed · 2014 · Journal Article
- Agrin requires specific proteins to selectively activate γ-aminobutyric acid neurons for pain suppression. — PubMed · 2014 · Journal Article
- AAVshRNA-mediated suppression of PTEN in adult rats in combination with salmon fibrin administration enables regenerative growth of corticospinal axons and enhances recovery of voluntary motor function after cervical spinal cord injury. — PubMed · 2014 · Journal Article
- Overexpression of the astrocyte glutamate transporter GLT1 exacerbates phrenic motor neuron degeneration, diaphragm compromise, and forelimb motor dysfunction following cervical contusion spinal cord injury. — PubMed · 2014 · Journal Article
- Overexpressing neuroglobin improves functional recovery by inhibiting neuronal apoptosis after spinal cord injury. — PubMed · 2014 · Journal Article
- Herpes simplex virus vector-mediated gene transfer of kynurenine aminotransferase improves detrusor overactivity in spinal cord-injured rats. — PubMed · 2014 · Journal Article
- Sox11 promotes endogenous neurogenesis and locomotor recovery in mice spinal cord injury. — PubMed · 2014 · Journal Article
- Large-scale chondroitin sulfate proteoglycan digestion with chondroitinase gene therapy leads to reduced pathology and modulates macrophage phenotype following spinal cord contusion injury. — PubMed · 2014 · Journal Article
- Gene therapy for neuropathic pain by silencing of TNF-α expression with lentiviral vectors targeting the dorsal root ganglion in mice. — PubMed · 2014 · Journal Article
- Does Nrf2 gene transfer facilitate recovery after contusion spinal cord injury? — PubMed · 2014 · Journal Article
- Effect of lentivirus-mediated RNA interference of APC-Cdh1 expression on spinal cord injury in rats. — PubMed · 2014 · Journal Article
- Overexpression of BDNF increases excitability of the lumbar spinal network and leads to robust early locomotor recovery in completely spinalized rats. — PubMed · 2014 · Journal Article
- Improved axonal regeneration of transected spinal cord mediated by multichannel collagen conduits functionalized with neurotrophin-3 gene. — PubMed · 2013 · Journal Article
- Transgenic overexpression of the cell adhesion molecule L1 in neurons facilitates recovery after mouse spinal cord injury. — PubMed · 2013 · Journal Article
- [Influence of Nogo extracellular peptide residues 1-40 gene modification on survival and differentiation of neural stem cells after transplantation]. — PubMed · 2013 · English Abstract
- Influences of HIF-lα on Bax/Bcl-2 and VEGF expressions in rats with spinal cord injury. — PubMed · 2013 · Journal Article
- Combination of chondroitinase ABC and AAV-NT3 promotes neural plasticity at descending spinal pathways after thoracic contusion in rats. — PubMed · 2013 · Journal Article
- Lentiviral mediated expression of a NGF-soluble Nogo receptor 1 fusion protein promotes axonal regeneration. — PubMed · 2013 · Journal Article
- Local injection of lentivirus encoding LINGO-1-shRNA promotes functional recovery in rats with complete spinal cord transection. — PubMed · 2013 · Journal Article
- Effect of neuroglobin genetically modified bone marrow mesenchymal stem cells transplantation on spinal cord injury in rabbits. — PubMed · 2013 · Journal Article
Where this was looked for, and when
The exact question each source was asked, the day it was asked, and what came back. A zero on this page is only honest if these are on it.
| ClinicalTrials.gov | asked, and it has nothing | asked on 2026-10-05 | the source found 0 · this programme has 0 · still to fetch 0 | aim: every record matching this question |
|---|---|---|---|---|
| Crossref | asked, and it answered | asked on 2026-09-17 | the source found 2898038 · this programme has 50 | aim: a sample of the most relevant records. This source ranks a bag of words, so its own total is the size of the corpus that shares some of them, never a set still owed. |
| PubMed | asked, and it answered | asked on 2026-09-17 | the source found 393 · this programme has 393 · still to fetch 0 | aim: every record matching this question |
The question asked
- ClinicalTrials.gov
("adeno-associated virus" OR "AAV vector" OR "lentiviral vector") - Crossref
spinal cord injury adeno-associated virus AAV vector - PubMed
("Spinal Cord Injuries"[MeSH Terms] OR "spinal cord injury"[Title/Abstract] OR "spinal cord injuries"[Title/Abstract] OR "spinal cord trauma"[Title/Abstract]) AND ("Dependovirus"[MeSH Terms] OR "Genetic Vectors"[MeSH Terms] OR "adeno-associated virus"[Title/Abstract] OR "AAV vector"[Title/Abstract] OR "lentiviral vector"[Title/Abstract])