A subject this map covers
Gene therapy
What belongs here
Introducing, silencing or editing a gene in nervous-system cells after injury.
What does not belong here, however close it looks
Cells engineered in a dish and then transplanted also belong to cell therapy.
What has been looked at
Counted from what the sources catalogue, not from reading the work. It says how much exists and over what span of years — never what any of it found.
- Registered or indexed as work in people: 185 records · 1992–2026
- Indexed as work in animals: 221 records · 1994–2026
- Indexed as laboratory work: 18 records · 1997–2021
- The source has not said who or what was studied: 99 records · 1997–2026
- Nobody has yet checked any of this against its original for this map, so none of it is on the checked shelf.
Checked
Records a person has read against the original and published into this map. These carry measurements, evidence states and a place on the ladder.
Nobody has checked a record on this subject yet.
Checking is done by a person, one record at a time, and this subject has not reached the queue yet. The shelf below is what the sources hold in the meantime; it has not been read by anybody.
Found in the scientific sources, not yet checked
Titles and identifiers as the sources publish them. Nobody here has read these papers, and nothing on this shelf is a result, a recommendation or evidence that anything works. Each line opens the original.
523 records
This grouping is the source's own cataloguing, not a reading of the paper. It says where a record was filed, not what it found.
Indexed as laboratory work
- NT-3 expression from engineered olfactory ensheathing glia promotes spinal sparing and regeneration. — PubMed · 2005 · Journal Article
- Olfactory ensheathing cells genetically modified to secrete GDNF to promote spinal cord repair. — PubMed · 2004 · Journal Article
- From bench to bedside: advances in stem cell biology and gene therapy. — PubMed · 2000 · Editorial
- Potential use of herpes simplex virus (HSV) vectors for gene therapy of neurological disorders. — PubMed · 1997 · Journal Article
The source has not said who or what was studied
- Stem Cell-Derived Exosomes Therapy for Spinal Cord Injury: Mechanisms and Prospects. — PubMed · 2026 · Journal Article
- Subpial Gene Delivery in the Mouse Spinal Cord to Evaluate Gene Expression — Crossref · 2026 · journal-article
- Subpial Gene Delivery in the Mouse Spinal Cord to Evaluate Gene Expression — Crossref · 2026 · journal-article
- Titer- and Intervention Timing-Dependent Functional Effects of AAV9-NeuroD1 Gene Therapy on Spinal Cord Injury. — PubMed · 2026 · Journal Article
- Examining Mgat5 upregulation's protective effects and underlying mechanisms in spinal cord injury. — PubMed · 2026 · Journal Article
- PBAE nanoparticle-mediated delivery of ASCL1 and NGN2 genes for astroglia-to-neuron reprogramming to remodel glial scar for spinal cord injury repair. — PubMed · 2026 · Journal Article
- AAV-mediated Gsx1 gene therapy demonstrates preclinical safety and efficacy in a mouse model of contusion spinal cord injury — Crossref · 2026 · journal-article
- The role of gene therapy in neural injury repair. — PubMed · 2026 · Journal Article
- Spinal cord injury and inflammatory mediators: Role in "fire barrier" formation and potential for neural regeneration. — PubMed · 2026 · Journal Article
- Axonal Regeneration, Growth Cone, and the FIGN Gene Family: A Comprehensive Review. — PubMed · 2025 · Journal Article
- Serum Nogo - A as a predictor of neurological recovery in spinal cord injury. — PubMed · 2025 · Journal Article
- AAV2retro Enters Axons of Passage and Extensively Transduces Corticospinal Neurons After Injection into Spinal White Matter. — PubMed · 2025 · Journal Article
- What Is New in Spinal Cord Injury Management: A Narrative Review on the Emerging Role of Nanotechnology. — PubMed · 2025 · Journal Article
- The Role of the Wnt/β-Catenin Signaling Pathway in the Pathogenesis and Treatment of Spinal Cord Injury: A Review of the Latest Experimental Data. — PubMed · 2025 · Journal Article
- Controlled release of MIF siRNA and GDNF protein from a photocurable scaffold efficiently repairs spinal cord injury. — PubMed · 2025 · Journal Article
- MicroRNA-219 in the central nervous system: a potential theranostic approach. — PubMed · 2024 · Journal Article
- Axonal Regeneration after Spinal Cord Injury: Molecular Mechanisms, Regulatory Pathways, and Novel Strategies. — PubMed · 2024 · Journal Article
- Reverse engineering spinal-cord injury. — PubMed · 2024 · News
- Virus-mediated neuron-specific retrograde gene delivery in spinal cord injury — Crossref · 2024 · journal-article
- Genetically engineered electrospinning contributes to spinal cord injury repair by regulating the immune microenvironment. — PubMed · 2024 · Journal Article
- Non-resolving neuroinflammation regulates axon regeneration in chronic spinal cord injury. — PubMed · 2024 · Preprint
- Phosphorylated S6K1 and 4E-BP1 play different roles in constitutively active Rheb-mediated retinal ganglion cell survival and axon regeneration after optic nerve injury. — PubMed · 2023 · Journal Article
- Molecular and cellular changes in the post-traumatic spinal cord remodeling after autoinfusion of a genetically-enriched leucoconcentrate in a mini-pig model. — PubMed · 2023 · Journal Article
- Gene Therapy Using Efficient Direct Lineage Reprogramming Technology for Neurological Diseases. — PubMed · 2023 · Journal Article
- Neuronal regeneration after injury: a new perspective on gene therapy. — PubMed · 2023 · Journal Article
- Brain and spinal cord trauma: what we know about the therapeutic potential of insulin growth factor 1 gene therapy. — PubMed · 2023 · Journal Article
- The potential of gene therapies for spinal cord injury repair: a systematic review and meta-analysis of pre-clinical studies. — PubMed · 2023 · Journal Article
- Prospects for the use of olfactory mucosa cells in bioprinting for the treatment of spinal cord injuries. — PubMed · 2023 · Journal Article
- Recent advances in nanomaterials for the treatment of spinal cord injury. — PubMed · 2022 · Journal Article
- Porcine Model of Spinal Cord Injury: A Systematic Review. — PubMed · 2022 · Journal Article
- Immunomodulatory Strategies for Spinal Cord Injury. — PubMed · 2022 · Journal Article
- The Translational Benefits of Sheep as Large Animal Models of Human Neurological Disorders. — PubMed · 2022 · Journal Article
- Recombinant Adenoviruses for Delivery of Therapeutics Following Spinal Cord Injury. — PubMed · 2022 · Journal Article
- Gene expression and bone loss following spinal cord injury — Crossref · 2022 · book-chapter
- Gene therapy of neuropathic pain after spinal cord injury — Crossref · 2022 · book-chapter
- Viral vector gene therapy approaches for regeneration and repair in spinal cord injury — Crossref · 2022 · book-chapter
- Planet of the AAVs: The Spinal Cord Injury Episode. — PubMed · 2021 · Journal Article
- Delivery of pOXR1 through an injectable liposomal nanoparticle enhances spinal cord injury regeneration by alleviating oxidative stress. — PubMed · 2021 · Journal Article
- Combination of epidural electrical stimulation with ex vivo triple gene therapy for spinal cord injury: a proof of principle study. — PubMed · 2021 · Journal Article
- Inhibition of lncRNA H19/miR-370-3p pathway mitigates neuronal apoptosis in an in vitro model of spinal cord injury (SCI). — PubMed · 2021 · Journal Article
- Gene-modified leucoconcentrate for personalized ex vivo gene therapy in a mini pig model of moderate spinal cord injury. — PubMed · 2021 · Journal Article
- Regeneration of Functional Neurons After Spinal Cord Injury via in situ NeuroD1-Mediated Astrocyte-to-Neuron Conversion. — PubMed · 2020 · Journal Article
- Graphene nanoribbons: A promising nanomaterial for biomedical applications. — PubMed · 2020 · Journal Article
- The combination of forskolin and VPA increases gene expression efficiency to the hypoxia/neuron-specific system. — PubMed · 2020 · Journal Article
- Ex Vivo Rat Transected Spinal Cord Slices as a Model to Assess Lentiviral Vector Delivery of Neurotrophin-3 and Short Hairpin RNA against NG2. — PubMed · 2020 · Journal Article
- Gene expression changes in the spinal cord segments following contusion spinal cord injury and its implications in gene therapy — Crossref · 2019 · journal-article
- Viral-Mediated Optogenetic Stimulation of Peripheral Motor Nerves in Non-human Primates. — PubMed · 2019 · Journal Article
- Astrocyte-selective AAV gene therapy through the endogenous GFAP promoter results in robust transduction in the rat spinal cord following injury — Crossref · 2019 · journal-article
- Faculty Opinions recommendation of Immune-evasive gene switch enables regulated delivery of chondroitinase after spinal cord injury. — Crossref · 2019 · dataset
- Faculty Opinions recommendation of Immune-evasive gene switch enables regulated delivery of chondroitinase after spinal cord injury. — Crossref · 2018 · dataset
- Author Correction: Three-dimensional aligned nanofibers-hydrogel scaffold for controlled non-viral drug/gene delivery to direct axon regeneration in spinal cord injury treatment. — PubMed · 2018 · Published Erratum
- At the Bench-Spinal Cord Injury — Crossref · 2018 · journal-article
- Faculty Opinions recommendation of Immune-evasive gene switch enables regulated delivery of chondroitinase after spinal cord injury. — Crossref · 2018 · dataset
- Triple-Gene Therapy for Stroke: A Proof-of-Concept in Vivo Study in Rats. — PubMed · 2018 · Journal Article
- Adeno-Associated Virus Vector Mediated Gene Delivery to Neurons and Glial Cells in Damaged Spinal Cord — Crossref · 2018 · book-chapter
- Experimental Gene Therapy with Serine-Histogranin and Endomorphin 1 for the Treatment of Chronic Neuropathic Pain. — PubMed · 2017 · Journal Article
Where this was looked for, and when
The exact question each source was asked, the day it was asked, and what came back. A zero on this page is only honest if these are on it.
| ClinicalTrials.gov | asked, and it has nothing | asked on 2026-09-29 | the source found 0 · this programme has 2 · still to fetch 0 | aim: every record matching this question |
|---|---|---|---|---|
| Crossref | asked, and it answered | asked on 2026-09-16 | the source found 3660371 · this programme has 50 | aim: a sample of the most relevant records. This source ranks a bag of words, so its own total is the size of the corpus that shares some of them, never a set still owed. |
| PubMed | asked, and it answered | asked on 2026-10-12 | the source found 1 · this programme has 495 · still to fetch 0 | aim: every record matching this question |
The question asked
- ClinicalTrials.gov
("gene therapy" OR "gene delivery") - Crossref
spinal cord injury gene therapy gene delivery - PubMed
("Spinal Cord Injuries"[MeSH Terms] OR "spinal cord injury"[Title/Abstract] OR "spinal cord injuries"[Title/Abstract] OR "spinal cord trauma"[Title/Abstract]) AND ("Genetic Therapy"[MeSH Terms] OR "gene therapy"[Title/Abstract] OR "gene delivery"[Title/Abstract])