A subject this map covers
Inflammation and immune response
What belongs here
What immune cells do after injury — both as damage and as a necessary part of healing.
What does not belong here, however close it looks
Infection and sepsis are clinical management, a separate subject.
What has been looked at
Counted from what the sources catalogue, not from reading the work. It says how much exists and over what span of years — never what any of it found.
- Registered or indexed as work in people: 769 records · 1981–2027
- Indexed as work in animals: 1704 records · 1975–2027
- Indexed as laboratory work: 73 records · 2001–2026
- The source has not said who or what was studied: 639 records · 1998–2026
- No matching published catalogue records are linked above. Human-review status must be checked on the evidence itself.
Published in this map
Catalogue records matching this subject. Publication here does not establish human review, measured results or effectiveness. Open a record to inspect its sources and evidence.
No published catalogue records match this subject yet.
This is a result within this map, not a claim that no research exists. The source records below can help you continue searching.
Found in the scientific sources, not yet checked
Titles and identifiers as the sources publish them. Nobody here has read these papers, and nothing on this shelf is a result, a recommendation or evidence that anything works. Each line opens the original.
3185 records
This grouping is the source's own cataloguing, not a reading of the paper. It says where a record was filed, not what it found.
Indexed as work in animals
- circ-Ncam2 (mmu_circ_0006413) Participates in LPS-Induced Microglia Activation and Neuronal Apoptosis via the TLR4/NF-κB Pathway. — PubMed · 2022 · Journal Article
- Exosome-Shuttled miR-672-5p from Anti-Inflammatory Microglia Repair Traumatic Spinal Cord Injury by Inhibiting AIM2/ASC/Caspase-1 Signaling Pathway Mediated Neuronal Pyroptosis. — PubMed · 2022 · Journal Article
- Fatty Acid-Binding Protein 4 Inhibition Promotes Locomotor and Autonomic Recovery in Rats following Spinal Cord Injury. — PubMed · 2022 · Journal Article
- Graphene-collagen cryogel controls neuroinflammation and fosters accelerated axonal regeneration in spinal cord injury. — PubMed · 2022 · Journal Article
- Granulin as an important immune molecule involved in lamprey tissue repair and regeneration by promoting cell proliferation and migration. — PubMed · 2022 · Letter
- NPC transplantation rescues sci-driven cAMP/EPAC2 alterations, leading to neuroprotection and microglial modulation. — PubMed · 2022 · Journal Article
- WKYMVm/FPR2 Alleviates Spinal Cord Injury by Attenuating the Inflammatory Response of Microglia. — PubMed · 2022 · Journal Article
- The Time Sequence of Gene Expression Changes after Spinal Cord Injury. — PubMed · 2022 · Journal Article
- Delayed administration of nafamostat mesylate inhibits thrombin-mediated blood-spinal cord barrier breakdown during acute spinal cord injury in rats. — PubMed · 2022 · Journal Article
- Microglia coordinate cellular interactions during spinal cord repair in mice. — PubMed · 2022 · Journal Article
- Impairment of autophagy after spinal cord injury potentiates neuroinflammation and motor function deficit in mice. — PubMed · 2022 · Journal Article
- Atractylenolide III ameliorates spinal cord injury in rats by modulating microglial/macrophage polarization. — PubMed · 2022 · Journal Article
- Effects of astrocytes and microglia on neuroinflammation after spinal cord injury and related immunomodulatory strategies. — PubMed · 2022 · Journal Article
- Insulin-Like Growth Factor-1 Enhances Motoneuron Survival and Inhibits Neuroinflammation After Spinal Cord Transection in Zebrafish. — PubMed · 2022 · Journal Article
- Mitochondrial-targeting antioxidant MitoQ modulates angiogenesis and promotes functional recovery after spinal cord injury. — PubMed · 2022 · Journal Article
- Neuroinflammation and apoptosis after surgery for a rat model of double-level cervical cord compression. — PubMed · 2022 · Journal Article
- Progranulin Promotes Functional Recovery in Rats with Acute Spinal Cord Injury via Autophagy-Induced Anti-inflammatory Microglial Polarization. — PubMed · 2022 · Journal Article
- Role of circadian rhythms in pathogenesis of acute CNS injuries: Insights from experimental studies. — PubMed · 2022 · Journal Article
- Sertoli cell transplantation attenuates microglial activation and inhibits TRPC6 expression in neuropathic pain induced by spinal cord injury. — PubMed · 2022 · Journal Article
- Single-cell sequencing reveals microglia induced angiogenesis by specific subsets of endothelial cells following spinal cord injury. — PubMed · 2022 · Journal Article
- Systematic analysis of critical genes and pathways identified a signature of neuropathic pain after spinal cord injury. — PubMed · 2022 · Journal Article
- Fecal Microbiota Transplantation Exerts Neuroprotective Effects in a Mouse Spinal Cord Injury Model by Modulating the Microenvironment at the Lesion Site. — PubMed · 2022 · Journal Article
- Apelin alleviated neuroinflammation and promoted endogenous neural stem cell proliferation and differentiation after spinal cord injury in rats. — PubMed · 2022 · Journal Article
- [Effect of M2-like macrophage/microglia-derived mitochondria transplantation in treatment of mouse spinal cord injury]. — PubMed · 2022 · Journal Article
- LncRNA KCNQ1OT1 promotes the apoptosis and inflammatory response of microglia by regulating the miR-589-5p/NPTN axis after spinal cord injury. — PubMed · 2022 · Journal Article
- Astrocytic Nrf2 expression protects spinal cord from oxidative stress following spinal cord injury in a male mouse model. — PubMed · 2022 · Journal Article
- Distinct Glycosylation Responses to Spinal Cord Injury in Regenerative and Nonregenerative Models. — PubMed · 2022 · Journal Article
- Cell type specific isolation of primary astrocytes and microglia from adult mouse spinal cord. — PubMed · 2022 · Journal Article
- Metformin promotes microglial cells to facilitate myelin debris clearance and accelerate nerve repairment after spinal cord injury. — PubMed · 2022 · Journal Article
- PBMSCs transplantation facilitates functional recovery after spinal cord injury by regulating microglia/macrophages plasticity. — PubMed · 2022 · Journal Article
- TLR4 aggravates microglial pyroptosis by promoting DDX3X-mediated NLRP3 inflammasome activation via JAK2/STAT1 pathway after spinal cord injury. — PubMed · 2022 · Journal Article
- Topoisomerase 1 inhibition modulates pyroptosis to improve recovery after spinal cord injury. — PubMed · 2022 · Journal Article
- Single-cell transcriptome analysis reveals the immune heterogeneity and the repopulation of microglia by Hif1α in mice after spinal cord injury. — PubMed · 2022 · Journal Article
- Exosomes-Loaded Electroconductive Hydrogel Synergistically Promotes Tissue Repair after Spinal Cord Injury via Immunoregulation and Enhancement of Myelinated Axon Growth. — PubMed · 2022 · Journal Article
- Immunomodulatory and regenerative effects of the full and fractioned adipose tissue derived stem cells secretome in spinal cord injury. — PubMed · 2022 · Journal Article
- Protective Effect of Mild Hypothermia on Spinal Cord Ischemia-Induced Delayed Paralysis and Spinal Cord Injury. — PubMed · 2022 · Journal Article
- SU16f inhibits fibrotic scar formation and facilitates axon regeneration and locomotor function recovery after spinal cord injury by blocking the PDGFRβ pathway. — PubMed · 2022 · Journal Article
- Long-term in vivo imaging of mouse spinal cord through an optically cleared intervertebral window. — PubMed · 2022 · Journal Article
- Trehalose inhibits ferroptosis via NRF2/HO-1 pathway and promotes functional recovery in mice with spinal cord injury. — PubMed · 2022 · Journal Article
- Ac-SDKP peptide improves functional recovery following spinal cord injury in a preclinical model. — PubMed · 2022 · Journal Article
- A Single Administration of Riluzole Applied Acutely After Spinal Cord Injury Attenuates Pro-inflammatory Activity and Improves Long-Term Functional Recovery in Rats. — PubMed · 2022 · Journal Article
- Ischemic postconditioning reduces spinal cord ischemia-reperfusion injury through ATP-sensitive potassium channel. — PubMed · 2022 · Journal Article
- Therapeutic induction of energy metabolism reduces neural tissue damage and increases microglia activation in severe spinal cord injury. — PubMed · 2022 · Journal Article
- Upregulation of G-protein Coupled Receptor 120 in Rats Following Spinal Cord Injury. — PubMed · 2022 · Journal Article
- Water Treadmill Training Ameliorates Neurite Outgrowth Inhibition Associated with NGR/RhoA/ROCK by Inhibiting Astrocyte Activation following Spinal Cord Injury. — PubMed · 2022 · Journal Article
- Interleukin-10 genetically modified clinical-grade mesenchymal stromal cells markedly reinforced functional recovery after spinal cord injury via directing alternative activation of macrophages. — PubMed · 2022 · Journal Article
- Pharmacologic Recruitment of Endogenous Neural Stem/Progenitor Cells for the Treatment of Spinal Cord Injury. — PubMed · 2022 · Journal Article
- Preliminary application of native Nephila edulis spider silk and fibrin implant causes granulomatous foreign body reaction in vivo in rat's spinal cord. — PubMed · 2022 · Journal Article
- Ultrasound stimulation improves inflammatory resolution, neuroprotection, and functional recovery after spinal cord injury. — PubMed · 2022 · Journal Article
- Temporal and spatial cellular and molecular pathological alterations with single-cell resolution in the adult spinal cord after injury. — PubMed · 2022 · Journal Article
- Neuroprotective effect of aldose reductase knockout in a mouse model of spinal cord injury involves NF-κB pathway. — PubMed · 2022 · Journal Article
- Melatonin ameliorates bupivacaine-induced spinal neurotoxicity in rats by suppressing neuronal NLRP3 inflammasome activation. — PubMed · 2022 · Journal Article
- Immune-responsive gene 1/itaconate activates nuclear factor erythroid 2-related factor 2 in microglia to protect against spinal cord injury in mice. — PubMed · 2022 · Journal Article
- Glycyrrhizic Acid Attenuates the Inflammatory Response After Spinal Cord Injury by Inhibiting High Mobility Group Box-1 Protein Through the p38/Jun N-Terminal Kinase Signaling Pathway. — PubMed · 2022 · Journal Article
- Zinc Promotes Microglial Autophagy Through NLRP3 Inflammasome Inactivation via XIST/miR-374a-5p Axis in Spinal Cord Injury. — PubMed · 2022 · Journal Article
- Activation of glucagon-like peptide-1 receptor in microglia attenuates neuroinflammation-induced glial scarring via rescuing Arf and Rho GAP adapter protein 3 expressions after nerve injury. — PubMed · 2022 · Journal Article
- A DAMP-scavenging, IL-10-releasing hydrogel promotes neural regeneration and motor function recovery after spinal cord injury. — PubMed · 2022 · Journal Article
- Daily acute intermittent hypoxia enhances serotonergic innervation of hypoglossal motor nuclei in rats with and without cervical spinal injury. — PubMed · 2022 · Comparative Study
- Ferrostatin-1 Alleviates White Matter Injury Via Decreasing Ferroptosis Following Spinal Cord Injury. — PubMed · 2022 · Journal Article
- Inhibition of CDK1 attenuates neuronal apoptosis and autophagy and confers neuroprotection after chronic spinal cord injury in vivo. — PubMed · 2022 · Journal Article
Where this was looked for, and when
The latest collection walk and the accumulated shelf have different scopes. A zero applies only to that source query and its date window; older records may remain on the shelf. It does not mean no research exists.
| ClinicalTrials.gov | latest collection walk returned no records | asked on 2026-10-05 Collection window: 2026-09-16 – 2026-10-05 | matched in this collection walk 0 · accumulated records across collection walks 3 · still to fetch in this walk 0 | aim: every record matching this question |
|---|---|---|---|---|
| Crossref | asked, and it answered | asked on 2026-09-16 Collection window: all dates before the end date – 2026-09-16 | matched in this collection walk 851312 · accumulated records across collection walks 48 | aim: a sample of the most relevant records. This source ranks a bag of words, so its own total is the size of the corpus that shares some of them, never a set still owed. |
| PubMed | asked, and it answered | asked on 2026-10-12 Collection window: 2026-09-17 – 2026-10-12 | matched in this collection walk 29 · accumulated records across collection walks 3219 · still to fetch in this walk 0 | aim: every record matching this question |
The question asked
- ClinicalTrials.gov
("neuroinflammation" OR "microglia" OR "immune response") - Crossref
spinal cord injury neuroinflammation microglia - PubMed
("Spinal Cord Injuries"[MeSH Terms] OR "spinal cord injury"[Title/Abstract] OR "spinal cord injuries"[Title/Abstract] OR "spinal cord trauma"[Title/Abstract]) AND ("Neurogenic Inflammation"[MeSH Terms] OR "Microglia"[MeSH Terms] OR "Neuroimmunomodulation"[MeSH Terms] OR "neuroinflammation"[Title/Abstract] OR "microglia"[Title/Abstract] OR "immune response"[Title/Abstract])