A subject this map covers
Inflammation and immune response
What belongs here
What immune cells do after injury — both as damage and as a necessary part of healing.
What does not belong here, however close it looks
Infection and sepsis are clinical management, a separate subject.
What has been looked at
Counted from what the sources catalogue, not from reading the work. It says how much exists and over what span of years — never what any of it found.
- Registered or indexed as work in people: 769 records · 1981–2027
- Indexed as work in animals: 1704 records · 1975–2027
- Indexed as laboratory work: 73 records · 2001–2026
- The source has not said who or what was studied: 639 records · 1998–2026
- No matching published catalogue records are linked above. Human-review status must be checked on the evidence itself.
Published in this map
Catalogue records matching this subject. Publication here does not establish human review, measured results or effectiveness. Open a record to inspect its sources and evidence.
No published catalogue records match this subject yet.
This is a result within this map, not a claim that no research exists. The source records below can help you continue searching.
Found in the scientific sources, not yet checked
Titles and identifiers as the sources publish them. Nobody here has read these papers, and nothing on this shelf is a result, a recommendation or evidence that anything works. Each line opens the original.
3185 records
This grouping is the source's own cataloguing, not a reading of the paper. It says where a record was filed, not what it found.
Indexed as work in animals
- Inhibition of NOX2 signaling limits pain-related behavior and improves motor function in male mice after spinal cord injury: Participation of IL-10/miR-155 pathways. — PubMed · 2019 · Journal Article
- Sexual Dimorphism of Pain Control: Analgesic Effects of Pioglitazone and Azithromycin in Chronic Spinal Cord Injury. — PubMed · 2019 · Journal Article
- Tranexamic acid reduces heme cytotoxicity via the TLR4/TNF axis and ameliorates functional recovery after spinal cord injury. — PubMed · 2019 · Journal Article
- Docosahexaenoic acid reduces microglia phagocytic activity via miR-124 and induces neuroprotection in rodent models of spinal cord contusion injury. — PubMed · 2019 · Journal Article
- Melatonin improves functional recovery in female rats after acute spinal cord injury by modulating polarization of spinal microglial/macrophages. — PubMed · 2019 · Journal Article
- Morphine increases macrophages at the lesion site following spinal cord injury: Protective effects of minocycline. — PubMed · 2019 · Journal Article
- Intraspinal administration of interleukin-7 promotes neuronal apoptosis and limits functional recovery through JAK/STAT5 pathway following spinal cord injury. — PubMed · 2019 · Journal Article
- FBXW5 reduction alleviates spinal cord injury (SCI) by blocking microglia activity: A mechanism involving p38 and JNK. — PubMed · 2019 · Journal Article
- Triptolide Suppressed the Microglia Activation to Improve Spinal Cord Injury Through miR-96/IKKβ/NF-κB Pathway. — PubMed · 2019 · Journal Article
- BET protein inhibition regulates cytokine production and promotes neuroprotection after spinal cord injury. — PubMed · 2019 · Journal Article
- A Causal Relationship in Spinal Cord Injury Rat Model Between Microglia Activation and EGFR/MAPK Detected by Overexpression of MicroRNA-325-3p. — PubMed · 2019 · Journal Article
- Aquaporin-4 expression dynamically varies after acute spinal cord injury-induced disruption of blood spinal cord barrier in rats. — PubMed · 2019 · Journal Article
- Histoarchitecture restoration of cerebellar sub-layers as a response to estradiol treatment following Kainic acid-induced spinal cord injury. — PubMed · 2019 · Journal Article
- Sodium Butyrate Exerts Neuroprotective Effects in Spinal Cord Injury. — PubMed · 2019 · Journal Article
- Characterizing the Neuroprotective Effects of S/B Remedy (Scutellaria baicalensis Georgi and Bupleurum scorzonerifolfium Willd) in Spinal Cord Injury. — PubMed · 2019 · Journal Article
- Macrophage centripetal migration drives spontaneous healing process after spinal cord injury. — PubMed · 2019 · Journal Article
- Macrolide derivatives reduce proinflammatory macrophage activation and macrophage-mediated neurotoxicity. — PubMed · 2019 · Journal Article
- Sustained interleukin-10 delivery reduces inflammation and improves motor function after spinal cord injury. — PubMed · 2019 · Journal Article
- Neural stem cell-derived small extracellular vesicles attenuate apoptosis and neuroinflammation after traumatic spinal cord injury by activating autophagy. — PubMed · 2019 · Journal Article
- Following spinal cord injury, PDE4B drives an acute, local inflammatory response and a chronic, systemic response exacerbated by gut dysbiosis and endotoxemia. — PubMed · 2019 · Journal Article
- Progesterone effects on oligodendrocyte differentiation in injured spinal cord. — PubMed · 2019 · Journal Article
- Activating Adiponectin Signaling with Exogenous AdipoRon Reduces Myelin Lipid Accumulation and Suppresses Macrophage Recruitment after Spinal Cord Injury. — PubMed · 2019 · Journal Article
- Bone Marrow-Derived Monocytes Drive the Inflammatory Microenvironment in Local and Remote Regions after Thoracic Spinal Cord Injury. — PubMed · 2019 · Journal Article
- Syngeneic, in contrast to allogeneic, mesenchymal stem cells have superior therapeutic potential following spinal cord injury. — PubMed · 2019 · Journal Article
- Devising micro/nano-architectures in multi-channel nerve conduits towards a pro-regenerative matrix for the repair of spinal cord injury. — PubMed · 2019 · Journal Article
- Inhibition of miR-214-5p attenuates inflammatory chemotaxis and nerve regeneration obstruction after spinal cord injury in rats. — PubMed · 2019 · Journal Article
- P2Y12 regulates microglia activation and excitatory synaptic transmission in spinal lamina II neurons during neuropathic pain in rodents. — PubMed · 2019 · Journal Article
- Microglia Promote Increased Pain Behavior through Enhanced Inflammation in the Spinal Cord during Repeated Social Defeat Stress. — PubMed · 2019 · Journal Article
- Exosomes Derived from Bone Mesenchymal Stem Cells Repair Traumatic Spinal Cord Injury by Suppressing the Activation of A1 Neurotoxic Reactive Astrocytes. — PubMed · 2019 · Journal Article
- Lysophosphatidic acid receptor type 2 activation contributes to secondary damage after spinal cord injury in mice. — PubMed · 2019 · Journal Article
- Reactivity of microglia and astrocytes after an excitotoxic injury induced by kainic acid in the rat spinal cord. — PubMed · 2019 · Journal Article
- Reducing age-dependent monocyte-derived macrophage activation contributes to the therapeutic efficacy of NADPH oxidase inhibition in spinal cord injury. — PubMed · 2019 · Journal Article
- Microglia are an essential component of the neuroprotective scar that forms after spinal cord injury. — PubMed · 2019 · Journal Article
- Polydatin attenuates spinal cord injury in rats by inhibiting oxidative stress and microglia apoptosis via Nrf2/HO-1 pathway. — PubMed · 2019 · Journal Article
- Activation of Melanocortin-4 Receptor by a Synthetic Agonist Inhibits Ethanolinduced Neuroinflammation in Rats. — PubMed · 2019 · Journal Article
- [Development of New Therapies for Neurodegenerative Diseases via Axonal Growth]. — PubMed · 2019 · Journal Article
- MiR-21 inhibitor improves locomotor function recovery by inhibiting IL-6R/JAK-STAT pathway-mediated inflammation after spinal cord injury in model of rat. — PubMed · 2019 · Journal Article
- Myxoma virus derived immune modulating proteins, M-T7 and Serp-1, reduce early inflammation after spinal cord injury in the rat model. — PubMed · 2019 · Journal Article
- Spinal Cord Injury in Rats Disrupts the Circadian System. — PubMed · 2018 · Journal Article
- Longitudinal Magnetic Resonance Imaging Analysis and Histological Characterization after Spinal Cord Injury in Two Mouse Strains with Different Functional Recovery: Gliosis as a Key Factor. — PubMed · 2018 · Journal Article
- Neuroprotection by Paeoniflorin against Nuclear Factor Kappa B-Induced Neuroinflammation on Spinal Cord Injury. — PubMed · 2018 · Journal Article
- LncRNA SNHG5 enhances astrocytes and microglia viability via upregulating KLF4 in spinal cord injury. — PubMed · 2018 · Journal Article
- Dynamic control of proinflammatory cytokines Il-1β and Tnf-α by macrophages in zebrafish spinal cord regeneration. — PubMed · 2018 · Journal Article
- Anti-inflammatory effects of Metformin improve the neuropathic pain and locomotor activity in spinal cord injured rats: introduction of an alternative therapy. — PubMed · 2018 · Journal Article
- Blood Glutamate Scavenger as a Novel Neuroprotective Treatment in Spinal Cord Injury. — PubMed · 2018 · Journal Article
- Bromodomain and extraterminal domain-containing protein inhibition attenuates acute inflammation after spinal cord injury. — PubMed · 2018 · Journal Article
- Dexmedetomidine Mitigates Microglia-Mediated Neuroinflammation through Upregulation of Programmed Cell Death Protein 1 in a Rat Spinal Cord Injury Model. — PubMed · 2018 · Journal Article
- Involvement of lysophosphatidic acid-induced astrocyte activation underlying the maintenance of partial sciatic nerve injury-induced neuropathic pain. — PubMed · 2018 · Journal Article
- 3D MALDI mass spectrometry imaging reveals specific localization of long-chain acylcarnitines within a 10-day time window of spinal cord injury. — PubMed · 2018 · Journal Article
- Astaxanthin attenuates neuroinflammation contributed to the neuropathic pain and motor dysfunction following compression spinal cord injury. — PubMed · 2018 · Journal Article
- CD200 modulates spinal cord injury neuroinflammation and outcome through CD200R1. — PubMed · 2018 · Journal Article
- Differential Response in Novel Stem Cell Niches of the Brain after Cervical Spinal Cord Injury and Traumatic Brain Injury. — PubMed · 2018 · Journal Article
- Overexpression of TUSC7 inhibits the inflammation caused by microglia activation via regulating miR-449a/PPAR-γ. — PubMed · 2018 · Journal Article
- The Chinese Medicine Wu-Tou Decoction Relieves Neuropathic Pain by Inhibiting Hippocampal Microglia Activation. — PubMed · 2018 · Journal Article
- Neuroprotection and immunomodulation following intraspinal axotomy of motoneurons by treatment with adult mesenchymal stem cells. — PubMed · 2018 · Journal Article
- Methylprednisolone treatment enhances early recovery following surgical decompression for degenerative cervical myelopathy without compromise to the systemic immune system. — PubMed · 2018 · Journal Article
- AKR1B1 Upregulation Contributes to Neuroinflammation and Astrocytes Proliferation by Regulating the Energy Metabolism in Rat Spinal Cord Injury. — PubMed · 2018 · Journal Article
- Combined effects of rat Schwann cells and 17β-estradiol in a spinal cord injury model. — PubMed · 2018 · Journal Article
- High mobility group box-1 (HMGB1) is increased in injured mouse spinal cord and can elicit neurotoxic inflammation. — PubMed · 2018 · Journal Article
- Immune-evasive gene switch enables regulated delivery of chondroitinase after spinal cord injury. — PubMed · 2018 · Journal Article
Where this was looked for, and when
The latest collection walk and the accumulated shelf have different scopes. A zero applies only to that source query and its date window; older records may remain on the shelf. It does not mean no research exists.
| ClinicalTrials.gov | latest collection walk returned no records | asked on 2026-10-05 Collection window: 2026-09-16 – 2026-10-05 | matched in this collection walk 0 · accumulated records across collection walks 3 · still to fetch in this walk 0 | aim: every record matching this question |
|---|---|---|---|---|
| Crossref | asked, and it answered | asked on 2026-09-16 Collection window: all dates before the end date – 2026-09-16 | matched in this collection walk 851312 · accumulated records across collection walks 48 | aim: a sample of the most relevant records. This source ranks a bag of words, so its own total is the size of the corpus that shares some of them, never a set still owed. |
| PubMed | asked, and it answered | asked on 2026-10-12 Collection window: 2026-09-17 – 2026-10-12 | matched in this collection walk 29 · accumulated records across collection walks 3219 · still to fetch in this walk 0 | aim: every record matching this question |
The question asked
- ClinicalTrials.gov
("neuroinflammation" OR "microglia" OR "immune response") - Crossref
spinal cord injury neuroinflammation microglia - PubMed
("Spinal Cord Injuries"[MeSH Terms] OR "spinal cord injury"[Title/Abstract] OR "spinal cord injuries"[Title/Abstract] OR "spinal cord trauma"[Title/Abstract]) AND ("Neurogenic Inflammation"[MeSH Terms] OR "Microglia"[MeSH Terms] OR "Neuroimmunomodulation"[MeSH Terms] OR "neuroinflammation"[Title/Abstract] OR "microglia"[Title/Abstract] OR "immune response"[Title/Abstract])