A subject this map covers
Inflammation and immune response
What belongs here
What immune cells do after injury — both as damage and as a necessary part of healing.
What does not belong here, however close it looks
Infection and sepsis are clinical management, a separate subject.
What has been looked at
Counted from what the sources catalogue, not from reading the work. It says how much exists and over what span of years — never what any of it found.
- Registered or indexed as work in people: 769 records · 1981–2027
- Indexed as work in animals: 1704 records · 1975–2027
- Indexed as laboratory work: 73 records · 2001–2026
- The source has not said who or what was studied: 639 records · 1998–2026
- No matching published catalogue records are linked above. Human-review status must be checked on the evidence itself.
Published in this map
Catalogue records matching this subject. Publication here does not establish human review, measured results or effectiveness. Open a record to inspect its sources and evidence.
No published catalogue records match this subject yet.
This is a result within this map, not a claim that no research exists. The source records below can help you continue searching.
Found in the scientific sources, not yet checked
Titles and identifiers as the sources publish them. Nobody here has read these papers, and nothing on this shelf is a result, a recommendation or evidence that anything works. Each line opens the original.
3185 records
This grouping is the source's own cataloguing, not a reading of the paper. It says where a record was filed, not what it found.
Indexed as work in animals
- ROCK inhibition with fasudil promotes early functional recovery of spinal cord injury in rats by enhancing microglia phagocytosis. — PubMed · 2016 · Journal Article
- Germline ablation of dermatan-4O-sulfotransferase1 reduces regeneration after mouse spinal cord injury. — PubMed · 2016 · Journal Article
- Cyclic AMP is a key regulator of M1 to M2a phenotypic conversion of microglia in the presence of Th2 cytokines. — PubMed · 2016 · Journal Article
- Aldose Reductase Regulates Microglia/Macrophages Polarization Through the cAMP Response Element-Binding Protein After Spinal Cord Injury in Mice. — PubMed · 2016 · Journal Article
- Early modulation of pro-inflammatory microglia by minocycline loaded nanoparticles confers long lasting protection after spinal cord injury. — PubMed · 2016 · Journal Article
- Genetic Ablation of Soluble TNF Does Not Affect Lesion Size and Functional Recovery after Moderate Spinal Cord Injury in Mice. — PubMed · 2016 · Journal Article
- MP Resulting in Autophagic Cell Death of Microglia through Zinc Changes against Spinal Cord Injury. — PubMed · 2016 · Journal Article
- Transplantation of Cerebral Dopamine Neurotrophic Factor Transducted BMSCs in Contusion Spinal Cord Injury of Rats: Promotion of Nerve Regeneration by Alleviating Neuroinflammation. — PubMed · 2016 · Journal Article
- An Up-regulation of IRF-1 After a Spinal Cord Injury: Implications for Neuronal Apoptosis. — PubMed · 2015 · Journal Article
- CISD2 serves a novel role as a suppressor of nitric oxide signalling and curcumin increases CISD2 expression in spinal cord injuries. — PubMed · 2015 · Journal Article
- Azithromycin drives alternative macrophage activation and improves recovery and tissue sparing in contusion spinal cord injury. — PubMed · 2015 · Journal Article
- T cell deficiency in spinal cord injury: altered locomotor recovery and whole-genome transcriptional analysis. — PubMed · 2015 · Journal Article
- A functional progesterone receptor is required for immunomodulation, reduction of reactive gliosis and survival of oligodendrocyte precursors in the injured spinal cord. — PubMed · 2015 · Journal Article
- Age decreases macrophage IL-10 expression: Implications for functional recovery and tissue repair in spinal cord injury. — PubMed · 2015 · Journal Article
- Expression of Peroxiredoxin 1 After Traumatic Spinal Cord Injury in Rats. — PubMed · 2015 · Journal Article
- Temporospatial expression of fibulin-1 after acute spinal cord injury in rats. — PubMed · 2015 · Journal Article
- MMP-3 secreted from endothelial cells of blood vessels after spinal cord injury activates microglia, leading to oligodendrocyte cell death. — PubMed · 2015 · Journal Article
- Stress exacerbates neuron loss and microglia proliferation in a rat model of excitotoxic lower motor neuron injury. — PubMed · 2015 · Journal Article
- Inhibition of NOX2 reduces locomotor impairment, inflammation, and oxidative stress after spinal cord injury. — PubMed · 2015 · Journal Article
- Cdk5 contributes to inflammation-induced thermal hyperalgesia mediated by the p38 MAPK pathway in microglia. — PubMed · 2015 · Journal Article
- Lack of galectin-3 improves the functional outcome and tissue sparing by modulating inflammatory response after a compressive spinal cord injury. — PubMed · 2015 · Journal Article
- Neuroprotective Effects of Direct Intrathecal Administration of Granulocyte Colony-Stimulating Factor in Rats with Spinal Cord Injury. — PubMed · 2015 · Journal Article
- Role of Toll like receptor 4 signaling pathway in the secondary damage induced by experimental spinal cord injury. — PubMed · 2015 · Journal Article
- Whole-body Vibration at Thoracic Resonance Induces Sustained Pain and Widespread Cervical Neuroinflammation in the Rat. — PubMed · 2015 · Journal Article
- Granulocyte colony-stimulating factor attenuates spinal cord injury-induced mechanical allodynia in adult rats. — PubMed · 2015 · Journal Article
- Remote-controlled eradication of astrogliosis in spinal cord injury via electromagnetically-induced dexamethasone release from "smart" nanowires. — PubMed · 2015 · Journal Article
- Effect of carnosine, methylprednisolone and their combined application on irisin levels in the plasma and brain of rats with acute spinal cord injury. — PubMed · 2015 · Journal Article
- Fibronectin Matrix Assembly after Spinal Cord Injury. — PubMed · 2015 · Journal Article
- Local Injection of Lenti-BDNF at the Lesion Site Promotes M2 Macrophage Polarization and Inhibits Inflammatory Response After Spinal Cord Injury in Mice. — PubMed · 2015 · Journal Article
- Neuroprotective effects of nitidine against traumatic CNS injury via inhibiting microglia activation. — PubMed · 2015 · Journal Article
- Decrease of mRNA Editing after Spinal Cord Injury is Caused by Down-regulation of ADAR2 that is Triggered by Inflammatory Response. — PubMed · 2015 · Journal Article
- Activation of Lysophosphatidic Acid Receptor Type 1 Contributes to Pathophysiology of Spinal Cord Injury. — PubMed · 2015 · Journal Article
- Toll-Like Receptors and Dectin-1, a C-Type Lectin Receptor, Trigger Divergent Functions in CNS Macrophages. — PubMed · 2015 · Journal Article
- Monitoring of Short-Term Erythropoietin Therapy in Rats with Acute Spinal Cord Injury Using Manganese-Enhanced Magnetic Resonance Imaging. — PubMed · 2015 · Journal Article
- Positively Charged Oligo[Poly(Ethylene Glycol) Fumarate] Scaffold Implantation Results in a Permissive Lesion Environment after Spinal Cord Injury in Rat. — PubMed · 2015 · Journal Article
- Early transplantation of mesenchymal stem cells after spinal cord injury relieves pain hypersensitivity through suppression of pain-related signaling cascades and reduced inflammatory cell recruitment. — PubMed · 2015 · Journal Article
- Spinal Glia Division Contributes to Conditioning Lesion-Induced Axon Regeneration Into the Injured Spinal Cord: Potential Role of Cyclic AMP-Induced Tissue Inhibitor of Metalloproteinase-1. — PubMed · 2015 · Journal Article
- Crosstalk between macrophages and astrocytes affects proliferation, reactive phenotype and inflammatory response, suggesting a role during reactive gliosis following spinal cord injury. — PubMed · 2015 · Journal Article
- In vivo two-photon imaging of axonal dieback, blood flow, and calcium influx with methylprednisolone therapy after spinal cord injury. — PubMed · 2015 · Journal Article
- Fluoxetine prevents oligodendrocyte cell death by inhibiting microglia activation after spinal cord injury. — PubMed · 2015 · Journal Article
- High-frequency transcutaneous electrical nerve stimulation alleviates spasticity after spinal contusion by inhibiting activated microglia in rats. — PubMed · 2015 · Journal Article
- Role of adaptor protein MyD88 in TLR-mediated preconditioning and neuroprotection after acute excitotoxicity. — PubMed · 2015 · Journal Article
- Macrophages in spinal cord injury: phenotypic and functional change from exposure to myelin debris. — PubMed · 2015 · Journal Article
- Adoptive transfer of M2 macrophages promotes locomotor recovery in adult rats after spinal cord injury. — PubMed · 2015 · Journal Article
- Down-sizing of neuronal network activity and density of presynaptic terminals by pathological acidosis are efficiently prevented by Diminazene Aceturate. — PubMed · 2015 · Journal Article
- Nanocarrier-mediated inhibition of macrophage migration inhibitory factor attenuates secondary injury after spinal cord injury. — PubMed · 2015 · Journal Article
- Hematogenous macrophage depletion reduces the fibrotic scar and increases axonal growth after spinal cord injury. — PubMed · 2015 · Journal Article
- Interleukin-33 treatment reduces secondary injury and improves functional recovery after contusion spinal cord injury. — PubMed · 2015 · Journal Article
- RhoA/ROCK pathway mediates p38 MAPK activation and morphological changes downstream of P2Y12/13 receptors in spinal microglia in neuropathic pain. — PubMed · 2015 · Journal Article
- Spinal cord injury induces a long-lasting upregulation of interleukin-1β in astrocytes around the central canal. — PubMed · 2015 · Journal Article
- Disrupted autophagy after spinal cord injury is associated with ER stress and neuronal cell death. — PubMed · 2015 · Journal Article
- Ablation of the transcription factors E2F1-2 limits neuroinflammation and associated neurological deficits after contusive spinal cord injury. — PubMed · 2015 · Journal Article
- Endogenous Two-Photon Excited Fluorescence Provides Label-Free Visualization of the Inflammatory Response in the Rodent Spinal Cord. — PubMed · 2015 · Journal Article
- Galectin-1 in injured rat spinal cord: implications for macrophage phagocytosis and neural repair. — PubMed · 2015 · Journal Article
- Inhibition of glial proliferation, promotion of axonal growth and myelin production by synthetic glycolipid: A new approach for spinal cord injury treatment. — PubMed · 2015 · Journal Article
- Rapamycin plays a neuroprotective effect after spinal cord injury via anti-inflammatory effects. — PubMed · 2015 · Journal Article
- Rosuvastatin attenuated the existing morphine tolerance in rats with L5 spinal nerve transection through inhibiting activation of astrocytes and phosphorylation of ERK42/44. — PubMed · 2015 · Journal Article
- Therapeutic Efficacy of E-64-d, a Selective Calpain Inhibitor, in Experimental Acute Spinal Cord Injury. — PubMed · 2015 · Journal Article
- Two-photon microscopy as a tool to investigate the therapeutic time window of methylprednisolone in a mouse spinal cord injury model. — PubMed · 2015 · Journal Article
- Chronic exposure to TGFβ1 regulates myeloid cell inflammatory response in an IRF7-dependent manner. — PubMed · 2014 · Journal Article
Where this was looked for, and when
The latest collection walk and the accumulated shelf have different scopes. A zero applies only to that source query and its date window; older records may remain on the shelf. It does not mean no research exists.
| ClinicalTrials.gov | latest collection walk returned no records | asked on 2026-10-05 Collection window: 2026-09-16 – 2026-10-05 | matched in this collection walk 0 · accumulated records across collection walks 3 · still to fetch in this walk 0 | aim: every record matching this question |
|---|---|---|---|---|
| Crossref | asked, and it answered | asked on 2026-09-16 Collection window: all dates before the end date – 2026-09-16 | matched in this collection walk 851312 · accumulated records across collection walks 48 | aim: a sample of the most relevant records. This source ranks a bag of words, so its own total is the size of the corpus that shares some of them, never a set still owed. |
| PubMed | asked, and it answered | asked on 2026-10-12 Collection window: 2026-09-17 – 2026-10-12 | matched in this collection walk 29 · accumulated records across collection walks 3219 · still to fetch in this walk 0 | aim: every record matching this question |
The question asked
- ClinicalTrials.gov
("neuroinflammation" OR "microglia" OR "immune response") - Crossref
spinal cord injury neuroinflammation microglia - PubMed
("Spinal Cord Injuries"[MeSH Terms] OR "spinal cord injury"[Title/Abstract] OR "spinal cord injuries"[Title/Abstract] OR "spinal cord trauma"[Title/Abstract]) AND ("Neurogenic Inflammation"[MeSH Terms] OR "Microglia"[MeSH Terms] OR "Neuroimmunomodulation"[MeSH Terms] OR "neuroinflammation"[Title/Abstract] OR "microglia"[Title/Abstract] OR "immune response"[Title/Abstract])