A subject this map covers
Inflammation and immune response
What belongs here
What immune cells do after injury — both as damage and as a necessary part of healing.
What does not belong here, however close it looks
Infection and sepsis are clinical management, a separate subject.
What has been looked at
Counted from what the sources catalogue, not from reading the work. It says how much exists and over what span of years — never what any of it found.
- Registered or indexed as work in people: 769 records · 1981–2027
- Indexed as work in animals: 1704 records · 1975–2027
- Indexed as laboratory work: 73 records · 2001–2026
- The source has not said who or what was studied: 639 records · 1998–2026
- No matching published catalogue records are linked above. Human-review status must be checked on the evidence itself.
Published in this map
Catalogue records matching this subject. Publication here does not establish human review, measured results or effectiveness. Open a record to inspect its sources and evidence.
No published catalogue records match this subject yet.
This is a result within this map, not a claim that no research exists. The source records below can help you continue searching.
Found in the scientific sources, not yet checked
Titles and identifiers as the sources publish them. Nobody here has read these papers, and nothing on this shelf is a result, a recommendation or evidence that anything works. Each line opens the original.
3185 records
This grouping is the source's own cataloguing, not a reading of the paper. It says where a record was filed, not what it found.
Indexed as work in animals
- High-dose corticosteroids after spinal cord injury reduce neural progenitor cell proliferation. — PubMed · 2009 · Journal Article
- Remote astrocytic and microglial activation modulates neuronal hyperexcitability and below-level neuropathic pain after spinal injury in rat. — PubMed · 2009 · Journal Article
- Activation of metabotropic glutamate receptor 5 improves recovery after spinal cord injury in rodents. — PubMed · 2009 · Journal Article
- Infiltrating blood-derived macrophages are vital cells playing an anti-inflammatory role in recovery from spinal cord injury in mice. — PubMed · 2009 · Journal Article
- Expression of the repulsive guidance molecule RGM and its receptor neogenin after spinal cord injury in sea lamprey. — PubMed · 2009 · Journal Article
- Glial and axonal responses in areas of Wallerian degeneration of the corticospinal and dorsal ascending tracts after spinal cord dorsal funiculotomy. — PubMed · 2009 · Journal Article
- Activation of dendritic-like cells and neural stem/progenitor cells in injured spinal cord by GM-CSF. — PubMed · 2009 · Journal Article
- Nicotine attenuates iNOS expression and contributes to neuroprotection in a compressive model of spinal cord injury. — PubMed · 2009 · Journal Article
- GM-CSF inhibits glial scar formation and shows long-term protective effect after spinal cord injury. — PubMed · 2009 · Journal Article
- Upregulation in rat spinal cord microglia of the nonintegrin laminin receptor 37 kDa-LRP following activation by a traumatic lesion or peripheral injury. — PubMed · 2009 · Journal Article
- Idazoxan attenuates spinal cord injury by enhanced astrocytic activation and reduced microglial activation in rat experimental autoimmune encephalomyelitis. — PubMed · 2009 · Journal Article
- Depletion of Ly6G/Gr-1 leukocytes after spinal cord injury in mice alters wound healing and worsens neurological outcome. — PubMed · 2009 · Journal Article
- Early microglial inhibition preemptively mitigates chronic pain development after experimental spinal cord injury. — PubMed · 2009 · Journal Article
- Multipotent mesenchymal stromal cells attenuate chronic inflammation and injury-induced sensitivity to mechanical stimuli in experimental spinal cord injury. — PubMed · 2009 · Journal Article
- Neuropathic pain behaviours in a chronic-relapsing model of experimental autoimmune encephalomyelitis (EAE). — PubMed · 2009 · Journal Article
- Deficiency in complement C1q improves histological and functional locomotor outcome after spinal cord injury. — PubMed · 2008 · Journal Article
- PPARgamma agonist rosiglitazone is neuroprotective after traumatic brain injury via anti-inflammatory and anti-oxidative mechanisms. — PubMed · 2008 · Journal Article
- Antagonism of sphingosine 1-phosphate receptor-2 enhances migration of neural progenitor cells toward an area of brain. — PubMed · 2008 · Journal Article
- Modulation of the secondary injury process after spinal cord injury in Bach1-deficient mice by heme oxygenase-1. — PubMed · 2008 · Journal Article
- Gliopathy ensures persistent inflammation and chronic pain after spinal cord injury. — PubMed · 2008 · Comment
- Activation of p38 MAP kinase is involved in central neuropathic pain following spinal cord injury. — PubMed · 2008 · Comparative Study
- Blocking connexin43 expression reduces inflammation and improves functional recovery after spinal cord injury. — PubMed · 2008 · Journal Article
- Neuroprotective effects of caspase-3 inhibition on functional recovery and tissue sparing after acute spinal cord injury. — PubMed · 2008 · Comparative Study
- Another barrier to regeneration in the CNS: activated macrophages induce extensive retraction of dystrophic axons through direct physical interactions. — PubMed · 2008 · Journal Article
- Immunohistochemical study of cathepsin D in the spinal cords of rats with clip compression injury. — PubMed · 2008 · Comparative Study
- Neuroprotective effect of moderate epidural hypothermia after spinal cord injury in rats. — PubMed · 2008 · Journal Article
- Propentofylline attenuates allodynia, glial activation and modulates GABAergic tone after spinal cord injury in the rat. — PubMed · 2008 · Comparative Study
- Remote activation of microglia and pro-inflammatory cytokines predict the onset and severity of below-level neuropathic pain after spinal cord injury in rats. — PubMed · 2008 · Journal Article
- SB203580, a p38 mitogen-activated protein kinase inhibitor, fails to improve functional outcome following a moderate spinal cord injury in rat. — PubMed · 2008 · Journal Article
- Dynamics of the inflammatory response after murine spinal cord injury revealed by flow cytometry. — PubMed · 2008 · Journal Article
- Functional recovery after spinal cord injury in mice through activation of microglia and dendritic cells after IL-12 administration. — PubMed · 2008 · Journal Article
- Rolipram attenuates acute oligodendrocyte death in the adult rat ventrolateral funiculus following contusive cervical spinal cord injury. — PubMed · 2008 · Journal Article
- Pregabalin as a neuroprotector after spinal cord injury in rats. — PubMed · 2008 · Journal Article
- Contralateral neuropathic pain and neuropathology in dorsal root ganglion and spinal cord following hemilateral nerve injury in rats. — PubMed · 2008 · Journal Article
- Altered beta-1,4-galactosyltransferase I expression during early inflammation after spinal cord contusion injury. — PubMed · 2008 · Journal Article
- Temporal-spatial expressions of p27kip1 and its phosphorylation on Serine-10 after acute spinal cord injury in adult rat: Implications for post-traumatic glial proliferation. — PubMed · 2008 · Journal Article
- Transforming growth factor-activated kinase 1 induced in spinal astrocytes contributes to mechanical hypersensitivity after nerve injury. — PubMed · 2008 · Journal Article
- Contuse lesion of the rat spinal cord of moderate intensity leads to a higher time-dependent secondary neurodegeneration than severe one. An open-window for experimental neuroprotective interventions. — PubMed · 2008 · Journal Article
- Detrimental effects of antiapoptotic treatments in spinal cord injury. — PubMed · 2008 · Journal Article
- Spatial distribution and acute anti-inflammatory effects of Methylprednisolone after sustained local delivery to the contused spinal cord. — PubMed · 2008 · Journal Article
- Stable in vivo imaging of densely populated glia, axons and blood vessels in the mouse spinal cord using two-photon microscopy. — PubMed · 2008 · Journal Article
- A molecular platform in neurons regulates inflammation after spinal cord injury. — PubMed · 2008 · Journal Article
- The protective effects of 15-deoxy-delta-(12,14)-prostaglandin J2 in spinal cord injury. — PubMed · 2008 · Journal Article
- Immune activation is required for NT-3-induced axonal plasticity in chronic spinal cord injury. — PubMed · 2008 · Journal Article
- Delayed accumulation of activated macrophages and inhibition of remyelination after spinal cord injury in an adult rodent model. — PubMed · 2008 · Journal Article
- Immunomodulatory effect of the purine nucleoside inosine following spinal cord contusion injury in rat. — PubMed · 2008 · Journal Article
- Selenium attenuates ROS-mediated apoptotic cell death of injured spinal cord through prevention of mitochondria dysfunction; in vitro and in vivo study. — PubMed · 2008 · Journal Article
- Increased phosphorylation of caveolin-1 in the spinal cord of irradiated rats. — PubMed · 2007 · Journal Article
- Modulation of thalamic nociceptive processing after spinal cord injury through remote activation of thalamic microglia by cysteine cysteine chemokine ligand 21. — PubMed · 2007 · Journal Article
- Real-time direct measurement of spinal cord blood flow at the site of compression: relationship between blood flow recovery and motor deficiency in spinal cord injury. — PubMed · 2007 · Comparative Study
- Distinct types of microglial activation in white and grey matter of rat lumbosacral cord after mid-thoracic spinal transection. — PubMed · 2007 · Journal Article
- Lithium enhances proliferation and neuronal differentiation of neural progenitor cells in vitro and after transplantation into the adult rat spinal cord. — PubMed · 2007 · Journal Article
- Spinal cord injury-induced expression of the antiangiogenic endostatin/collagen XVIII in areas of vascular remodelling. — PubMed · 2007 · Journal Article
- Upregulation of vascular endothelial growth factor receptors Flt-1 and Flk-1 following acute spinal cord contusion in rats. — PubMed · 2007 · Journal Article
- Minocycline alleviates death of oligodendrocytes by inhibiting pro-nerve growth factor production in microglia after spinal cord injury. — PubMed · 2007 · Journal Article
- Cytoplasmic extracts from adipose tissue stromal cells alleviates secondary damage by modulating apoptosis and promotes functional recovery following spinal cord injury. — PubMed · 2007 · Journal Article
- Phosphorylation of Bcl-xL after spinal cord injury. — PubMed · 2007 · Journal Article
- Vaccination with a neural-derived peptide plus administration of glutathione improves the performance of paraplegic rats. — PubMed · 2007 · Journal Article
- Attenuation of astrogliosis by suppressing of microglial proliferation with the cell cycle inhibitor olomoucine in rat spinal cord injury model. — PubMed · 2007 · Journal Article
- Impairment of the mitochondrial respiratory enzyme activity triggers sequential activation of apoptosis-inducing factor-dependent and caspase-dependent signaling pathways to induce apoptosis after spinal cord injury. — PubMed · 2007 · Journal Article
Where this was looked for, and when
The latest collection walk and the accumulated shelf have different scopes. A zero applies only to that source query and its date window; older records may remain on the shelf. It does not mean no research exists.
| ClinicalTrials.gov | latest collection walk returned no records | asked on 2026-10-05 Collection window: 2026-09-16 – 2026-10-05 | matched in this collection walk 0 · accumulated records across collection walks 3 · still to fetch in this walk 0 | aim: every record matching this question |
|---|---|---|---|---|
| Crossref | asked, and it answered | asked on 2026-09-16 Collection window: all dates before the end date – 2026-09-16 | matched in this collection walk 851312 · accumulated records across collection walks 48 | aim: a sample of the most relevant records. This source ranks a bag of words, so its own total is the size of the corpus that shares some of them, never a set still owed. |
| PubMed | asked, and it answered | asked on 2026-10-12 Collection window: 2026-09-17 – 2026-10-12 | matched in this collection walk 29 · accumulated records across collection walks 3219 · still to fetch in this walk 0 | aim: every record matching this question |
The question asked
- ClinicalTrials.gov
("neuroinflammation" OR "microglia" OR "immune response") - Crossref
spinal cord injury neuroinflammation microglia - PubMed
("Spinal Cord Injuries"[MeSH Terms] OR "spinal cord injury"[Title/Abstract] OR "spinal cord injuries"[Title/Abstract] OR "spinal cord trauma"[Title/Abstract]) AND ("Neurogenic Inflammation"[MeSH Terms] OR "Microglia"[MeSH Terms] OR "Neuroimmunomodulation"[MeSH Terms] OR "neuroinflammation"[Title/Abstract] OR "microglia"[Title/Abstract] OR "immune response"[Title/Abstract])