A subject this map covers
Inflammation and immune response
What belongs here
What immune cells do after injury — both as damage and as a necessary part of healing.
What does not belong here, however close it looks
Infection and sepsis are clinical management, a separate subject.
What has been looked at
Counted from what the sources catalogue, not from reading the work. It says how much exists and over what span of years — never what any of it found.
- Registered or indexed as work in people: 769 records · 1981–2027
- Indexed as work in animals: 1704 records · 1975–2027
- Indexed as laboratory work: 73 records · 2001–2026
- The source has not said who or what was studied: 639 records · 1998–2026
- No matching published catalogue records are linked above. Human-review status must be checked on the evidence itself.
Published in this map
Catalogue records matching this subject. Publication here does not establish human review, measured results or effectiveness. Open a record to inspect its sources and evidence.
No published catalogue records match this subject yet.
This is a result within this map, not a claim that no research exists. The source records below can help you continue searching.
Found in the scientific sources, not yet checked
Titles and identifiers as the sources publish them. Nobody here has read these papers, and nothing on this shelf is a result, a recommendation or evidence that anything works. Each line opens the original.
3185 records
This grouping is the source's own cataloguing, not a reading of the paper. It says where a record was filed, not what it found.
Indexed as work in animals
- Structural changes of anterior horn neurons and their synaptic input caudal to a low thoracic spinal cord hemisection in the adult rat: a light and electron microscopic study. — PubMed · 1995 · Journal Article
- Secondary cell death and the inflammatory reaction after dorsal hemisection of the rat spinal cord. — PubMed · 1994 · Journal Article
- Elevation of the neurotoxin quinolinic acid occurs following spinal cord trauma. — PubMed · 1994 · Journal Article
- Differential expression of carbonic anhydrase isozymes in microglial cell types. — PubMed · 1993 · Comparative Study
- Differential expression of MHC class II antigen in the contused rat spinal cord. — PubMed · 1993 · Journal Article
- Ultrastructural study on avulsion effects of the cat cervical moto-axonal pathways in the spinal cord. — PubMed · 1993 · Journal Article
- Morphological responses to local CNS trauma: sprouting and synaptogenesis within membranes implanted into mature cerebral cortex of the rat. — PubMed · 1987 · Journal Article
- Immunocomplexes in rat and rabbit spinal cord after injury. — PubMed · 1987 · Journal Article
- Monocytes become macrophages; they do not become microglia: a light and electron microscopic autoradiographic study using 125-iododeoxyuridine. — PubMed · 1986 · Journal Article
- Non-specific esterase activity in reactive cells in injured nervous tissue labeled with 3H-thymidine or 125iododeoxyuridine injected before injury. — PubMed · 1980 · Journal Article
- Fine structure of reactive cells in injured nervous tissue labeled with 3H-thymidine injected before injury. — PubMed · 1978 · Journal Article
- Recovery in rats after spinal cord injury. — PubMed · 1976 · Journal Article
- The relationship between microglia and brain macrophages. Experimental investigations. — PubMed · 1975 · Journal Article
Indexed as laboratory work
- A Polydopamine-coated Engineered Type II Collagen Scaffold for Motor Neuron Organization and Spinal Cord Injury Regeneration. — PubMed · 2026 · Journal Article
- Thiolutin attenuates neuroinflammation and neuronal apoptosis by suppressing microglial pyroptosis through NLRP3 inflammasome inhibition after spinal cord injury. — PubMed · 2026 · Journal Article
- Rethinking Neuroregenerative Microenvironments: Synergy Between Bioengineering and Organoids. — PubMed · 2026 · Journal Article
- The Dual Role of Gastrodin in Spinal Cord Injury: Microglial Phenotype Switching and Neuronal Survival via PI3K/AKT Activation. — PubMed · 2026 · Journal Article
- Engineering integrin αvβ8-targeted extracellular vesicles to deliver BDNF mRNA for motor recovery in spinal cord injury. — PubMed · 2026 · Journal Article
- Dental pulp stem cell-derived exosomes promote axonal repair in spinal cord injury by suppressing neuroinflammation and apoptosis. — PubMed · 2026 · Journal Article
- Human spinal cord microglia/macrophages culture: Accutase digestion and non-enzymatic purification. — PubMed · 2025 · Journal Article
- Conductive Nanocomposite Hydrogels for Neural Tissue Engineering: A Systematic Scoping Review of Recent Trends. — PubMed · 2025 · Journal Article
- Advancements in Spinal Cord Injury Treatment: Integrating Drug Delivery, Biophysical Stimulation, Cell-Based Therapies, and Tissue Engineering Approaches. — PubMed · 2025 · Journal Article
- Peripheral Blood-Derived Mesenchymal Stem Cells Promote A2 Phenotype Polarization in Astrocytes via TGF-β-Mediated PI3K/Akt Pathway Activation. — PubMed · 2025 · Journal Article
- Assessing Microglial Phagocytosis of Myelin Debris in vitro Under Repeated Magnetic Stimulation. — PubMed · 2025 · Journal Article
- Bone Tissue Engineering: From Biomaterials to Clinical Trials. — PubMed · 2025 · Journal Article
- Axonal Growth and Fasciculation of Spinal Neurons Promoted by Aldynoglia in Alkaline Fibrin Hydrogel: Influence of Tol-51 Sulfoglycolipid. — PubMed · 2024 · Journal Article
- A 3D-Printed Dual Driving Forces Scaffold with Self-Promoted Cell Absorption for Spinal Cord Injury Repair. — PubMed · 2023 · Journal Article
- Construction and optimization of a coculture system of mouse brain microvascular endothelial cells and myelin debris. — PubMed · 2023 · Journal Article
- In vivo neural tissue engineering using adipose-derived mesenchymal stem cells and fibrin matrix. — PubMed · 2023 · Journal Article
- A new method for primary culture of microglia in rats with spinal cord injury. — PubMed · 2022 · Journal Article
- Bile acids attenuate PKM2 pathway activation in proinflammatory microglia. — PubMed · 2022 · Journal Article
- Neuroinflammation in Primary Cultures of the Rat Spinal Dorsal Horn Is Attenuated in the Presence of Adipose Tissue-Derived Medicinal Signalling Cells (AdMSCs) in a Co-cultivation Model. — PubMed · 2022 · Journal Article
- In Vitro Study of Human Immune Responses to Hyaluronic Acid Hydrogels, Recombinant Spidroins and Human Neural Progenitor Cells of Relevance to Spinal Cord Injury Repair. — PubMed · 2021 · Journal Article
- D-dopachrome tautomerase activates COX2/PGE(2) pathway of astrocytes to mediate inflammation following spinal cord injury. — PubMed · 2021 · Journal Article
- MicroRNA-223 targets NLRP3 to relieve inflammation and alleviate spinal cord injury. — PubMed · 2020 · Journal Article
- A Strategy Toward Bridging a Complete Spinal Cord Lesion Using Stretch-Grown Axons. — PubMed · 2020 · Journal Article
- IL-13 Ameliorates Neuroinflammation and Promotes Functional Recovery after Traumatic Brain Injury. — PubMed · 2020 · Journal Article
- Knockdown of long noncoding RNA XIST mitigates the apoptosis and inflammatory injury of microglia cells after spinal cord injury through miR-27a/Smurf1 axis. — PubMed · 2020 · Journal Article
- The superiority of conditioned medium derived from rapidly expanded mesenchymal stem cells for neural repair. — PubMed · 2019 · Journal Article
- Effect of Differently Polarized Macrophages on Proliferation and Differentiation of Ependymal Cells from Adult Spinal Cord. — PubMed · 2019 · Journal Article
- MiR-137-5p alleviates inflammation by upregulating IL-10R1 expression in rats with spinal cord injury. — PubMed · 2019 · Journal Article
- MiR-92b-5p inhibitor suppresses IL-18 mediated inflammatory amplification after spinal cord injury via IL-18BP up-regulation. — PubMed · 2019 · Journal Article
- Pifithrin-μ modulates microglial activation and promotes histological recovery following spinal cord injury. — PubMed · 2019 · Journal Article
- Establishing an Organotypic System for Investigating Multimodal Neural Repair Effects of Human Mesenchymal Stromal Stem Cells. — PubMed · 2018 · Journal Article
- Polycaprolactone/polysialic acid hybrid, multifunctional nanofiber scaffolds for treatment of spinal cord injury. — PubMed · 2018 · Journal Article
- Effect of hyaluronic acid hydrogels containing astrocyte-derived extracellular matrix and/or V2a interneurons on histologic outcomes following spinal cord injury. — PubMed · 2018 · Journal Article
- Dl-3-n-butylphthalide attenuates acute inflammatory activation in rats with spinal cord injury by inhibiting microglial TLR4/NF-κB signalling. — PubMed · 2017 · Journal Article
- Abnormalities in A-to-I RNA editing patterns in CNS injuries correlate with dynamic changes in cell type composition. — PubMed · 2017 · Journal Article
- Axonal outgrowth stimulation after alginate/mesenchymal stem cell therapy in injured rat spinal cord. — PubMed · 2017 · Journal Article
- Galectin-1 circumvents lysolecithin-induced demyelination through the modulation of microglial polarization/phagocytosis and oligodendroglial differentiation. — PubMed · 2016 · Journal Article
- Tissue Engineering Approaches to Modulate the Inflammatory Milieu following Spinal Cord Injury. — PubMed · 2016 · Journal Article
- Axonally derived matrilin-2 induces proinflammatory responses that exacerbate autoimmune neuroinflammation. — PubMed · 2014 · Journal Article
- Interleukin-1 receptor antagonist promotes survival of ventral horn neurons and suppresses microglial activation in mouse spinal cord slice cultures. — PubMed · 2014 · Journal Article
- Effects of cerebrolysin on motor-neuron-like NSC-34 cells. — PubMed · 2014 · Journal Article
- Abrogation of β-catenin signaling in oligodendrocyte precursor cells reduces glial scarring and promotes axon regeneration after CNS injury. — PubMed · 2014 · Journal Article
- Programmed death 1 deficiency induces the polarization of macrophages/microglia to the M1 phenotype after spinal cord injury in mice. — PubMed · 2014 · Journal Article
- Neural progenitor cell apoptosis and differentiation were affected by activated microglia in spinal cord slice culture. — PubMed · 2014 · Journal Article
- Selective nanovector mediated treatment of activated proinflammatory microglia/macrophages in spinal cord injury. — PubMed · 2013 · Journal Article
- Gene expression changes in the injured spinal cord following transplantation of mesenchymal stem cells or olfactory ensheathing cells. — PubMed · 2013 · Journal Article
- Culturing microglia from the neonatal and adult central nervous system. — PubMed · 2013 · Journal Article
Where this was looked for, and when
The latest collection walk and the accumulated shelf have different scopes. A zero applies only to that source query and its date window; older records may remain on the shelf. It does not mean no research exists.
| ClinicalTrials.gov | latest collection walk returned no records | asked on 2026-10-05 Collection window: 2026-09-16 – 2026-10-05 | matched in this collection walk 0 · accumulated records across collection walks 3 · still to fetch in this walk 0 | aim: every record matching this question |
|---|---|---|---|---|
| Crossref | asked, and it answered | asked on 2026-09-16 Collection window: all dates before the end date – 2026-09-16 | matched in this collection walk 851312 · accumulated records across collection walks 48 | aim: a sample of the most relevant records. This source ranks a bag of words, so its own total is the size of the corpus that shares some of them, never a set still owed. |
| PubMed | asked, and it answered | asked on 2026-10-12 Collection window: 2026-09-17 – 2026-10-12 | matched in this collection walk 29 · accumulated records across collection walks 3219 · still to fetch in this walk 0 | aim: every record matching this question |
The question asked
- ClinicalTrials.gov
("neuroinflammation" OR "microglia" OR "immune response") - Crossref
spinal cord injury neuroinflammation microglia - PubMed
("Spinal Cord Injuries"[MeSH Terms] OR "spinal cord injury"[Title/Abstract] OR "spinal cord injuries"[Title/Abstract] OR "spinal cord trauma"[Title/Abstract]) AND ("Neurogenic Inflammation"[MeSH Terms] OR "Microglia"[MeSH Terms] OR "Neuroimmunomodulation"[MeSH Terms] OR "neuroinflammation"[Title/Abstract] OR "microglia"[Title/Abstract] OR "immune response"[Title/Abstract])