A subject this map covers
Neuroprotection
What belongs here
Attempts to stop the second, delayed wave of damage in the first hours and days.
What does not belong here, however close it looks
Restoring function lost months earlier is repair, not neuroprotection.
What has been looked at
Counted from what the sources catalogue, not from reading the work. It says how much exists and over what span of years — never what any of it found.
- Registered or indexed as work in people: 1169 records · 1978–2027
- Indexed as work in animals: 1885 records · 1977–2026
- Indexed as laboratory work: 80 records · 1996–2026
- The source has not said who or what was studied: 572 records · 1991–2026
- No matching published catalogue records are linked above. Human-review status must be checked on the evidence itself.
Published in this map
Catalogue records matching this subject. Publication here does not establish human review, measured results or effectiveness. Open a record to inspect its sources and evidence.
No published catalogue records match this subject yet.
This is a result within this map, not a claim that no research exists. The source records below can help you continue searching.
Found in the scientific sources, not yet checked
Titles and identifiers as the sources publish them. Nobody here has read these papers, and nothing on this shelf is a result, a recommendation or evidence that anything works. Each line opens the original.
3706 records
This grouping is the source's own cataloguing, not a reading of the paper. It says where a record was filed, not what it found.
Indexed as work in animals
- Resolvin D3 Promotes Inflammatory Resolution, Neuroprotection, and Functional Recovery After Spinal Cord Injury. — PubMed · 2021 · Journal Article
- The voltage-gated proton channel Hv1 plays a detrimental role in contusion spinal cord injury via extracellular acidosis-mediated neuroinflammation. — PubMed · 2021 · Journal Article
- Uric acid released from poly(ε-caprolactone) fibers as a treatment platform for spinal cord injury. — PubMed · 2021 · Journal Article
- Selenium-Doped Carbon Quantum Dots Efficiently Ameliorate Secondary Spinal Cord Injury via Scavenging Reactive Oxygen Species. — PubMed · 2020 · Journal Article
- Asiaticoside Inhibits Neuronal Apoptosis and Promotes Functional Recovery After Spinal Cord Injury in Rats. — PubMed · 2020 · Journal Article
- Inflammatory response and oxidative stress attenuated by sulfiredoxin‑1 in neuron‑like cells depends on nuclear factor erythroid‑2‑related factor 2. — PubMed · 2020 · Journal Article
- IP(3)R-mediated intra-axonal Ca(2+) release contributes to secondary axonal degeneration following contusive spinal cord injury. — PubMed · 2020 · Journal Article
- MiR-124 improves spinal cord injury in rats by activating the Wnt/β-catenin signaling pathway. — PubMed · 2020 · Letter
- Transplantation of neural stem cells preconditioned with high‑mobility group box 1 facilitates functional recovery after spinal cord injury in rats. — PubMed · 2020 · Journal Article
- CCL3 contributes to secondary damage after spinal cord injury. — PubMed · 2020 · Journal Article
- Therapeutic effect of metformin on inflammation and apoptosis after spinal cord injury in rats through the Wnt/β-catenin signaling pathway. — PubMed · 2020 · Journal Article
- Serial Systemic Injections of Endotoxin (LPS) Elicit Neuroprotective Spinal Cord Microglia through IL-1-Dependent Cross Talk with Endothelial Cells. — PubMed · 2020 · Journal Article
- Intravenous delivery of mesenchymal stem cells protects both white and gray matter in spinal cord ischemia. — PubMed · 2020 · Journal Article
- Complement C6 deficiency exacerbates pathophysiology after spinal cord injury. — PubMed · 2020 · Journal Article
- Conditional Ablation of Myeloid TNF Improves Functional Outcome and Decreases Lesion Size after Spinal Cord Injury in Mice. — PubMed · 2020 · Journal Article
- FTY720 in CNS injuries: Molecular mechanisms and therapeutic potential. — PubMed · 2020 · Journal Article
- Gallic acid attenuates blood-spinal cord barrier disruption by inhibiting Jmjd3 expression and activation after spinal cord injury. — PubMed · 2020 · Journal Article
- Intrathecal Delivery of BDNF Into the Lumbar Cistern Re-Engages Locomotor Stepping After Spinal Cord Injury. — PubMed · 2020 · Journal Article
- miR-27a promotion resulting from silencing of HDAC3 facilitates the recovery of spinal cord injury by inhibiting PAK6 expression in rats. — PubMed · 2020 · Journal Article
- Role of ABT888, a Novel Poly(ADP-Ribose) Polymerase (PARP) Inhibitor in Countering Autophagy and Apoptotic Processes Associated to Spinal Cord Injury. — PubMed · 2020 · Journal Article
- Sex-Related Differences in Anxiety and Functional Recovery after Spinal Cord Injury in Mice. — PubMed · 2020 · Journal Article
- Two episodes of remote ischemia preconditioning improve motor and sensory function of hind limbs after spinal cord ischemic injury. — PubMed · 2020 · Journal Article
- Wnt-3a improves functional recovery through autophagy activation via inhibiting the mTOR signaling pathway after spinal cord injury. — PubMed · 2020 · Journal Article
- Inhibiting HMGB1-RAGE axis prevents pro-inflammatory macrophages/microglia polarization and affords neuroprotection after spinal cord injury. — PubMed · 2020 · Journal Article
- Enolase inhibition alters metabolic hormones and inflammatory factors to promote neuroprotection in spinal cord injury. — PubMed · 2020 · Journal Article
- Erythropoietin-Induced Autophagy Protects Against Spinal Cord Injury and Improves Neurological Function via the Extracellular-Regulated Protein Kinase Signaling Pathway. — PubMed · 2020 · Journal Article
- Neuroprotection of melatonin on spinal cord injury by activating autophagy and inhibiting apoptosis via SIRT1/AMPK signaling pathway. — PubMed · 2020 · Journal Article
- Novel Role of HAX-1 in Neurons Protection After Spinal Cord Injury Involvement of IRE-1. — PubMed · 2020 · Journal Article
- Near-infrared light-triggered NO release for spinal cord injury repair. — PubMed · 2020 · Journal Article
- Bilateral cervical contusion spinal cord injury: A mouse model to evaluate sensorimotor function. — PubMed · 2020 · Journal Article
- l-Theanine improves functional recovery after traumatic spinal cord injury in rats. — PubMed · 2020 · Journal Article
- Proanthocyanidin promotes functional recovery of spinal cord injury via inhibiting ferroptosis. — PubMed · 2020 · Journal Article
- CRID3, a blocker of apoptosis associated speck like protein containing a card, ameliorates murine spinal cord injury by improving local immune microenvironment. — PubMed · 2020 · Journal Article
- Neuroprotective effect of gastrodin in methamphetamine-induced apoptosis through regulating cAMP/PKA/CREB pathway in cortical neuron. — PubMed · 2020 · Journal Article
- Sitagliptin improves functional recovery via GLP-1R-induced anti-apoptosis and facilitation of axonal regeneration after spinal cord injury. — PubMed · 2020 · Journal Article
- Revealing the Therapeutic Potential of Botulinum Neurotoxin Type A in Counteracting Paralysis and Neuropathic Pain in Spinally Injured Mice. — PubMed · 2020 · Journal Article
- A Western diet impairs CNS energy homeostasis and recovery after spinal cord injury: Link to astrocyte metabolism. — PubMed · 2020 · Journal Article
- Pycnogenol achieves neuroprotective effects in rats with spinal cord injury by stabilizing the mitochondrial membrane potential. — PubMed · 2020 · Journal Article
- Thermosensitive heparin-poloxamer hydrogel encapsulated bFGF and NGF to treat spinal cord injury. — PubMed · 2020 · Journal Article
- Anti-IL-20 antibody improved motor function and reduced glial scar formation after traumatic spinal cord injury in rats. — PubMed · 2020 · Journal Article
- Neuroprotection of netrin-1 on neurological recovery via Wnt/β-catenin signaling pathway after spinal cord injury. — PubMed · 2020 · Journal Article
- Effects of combined treatment of minocycline and methylprednisolone on the expression of tumor necrosis factor alpha and interleukine-6 in experimental spinal cord injury: a light and electron microscopic study. — PubMed · 2020 · Journal Article
- Bioenergetic restoration and neuroprotection after therapeutic targeting of mitoNEET: New mechanism of pioglitazone following traumatic brain injury. — PubMed · 2020 · Journal Article
- Oral treatment with glycyrrhizin inhibits NLRP3 inflammasome activation and promotes microglial M2 polarization after traumatic spinal cord injury. — PubMed · 2020 · Journal Article
- LncGBP9/miR-34a axis drives macrophages toward a phenotype conducive for spinal cord injury repair via STAT1/STAT6 and SOCS3. — PubMed · 2020 · Journal Article
- Designer, injectable gels to prevent transplanted Schwann cell loss during spinal cord injury therapy. — PubMed · 2020 · Journal Article
- Riluzole improves functional recovery after acute spinal cord injury in rats and may be associated with changes in spinal microglia/macrophages polarization. — PubMed · 2020 · Journal Article
- MicroRNA-129-5p alleviates spinal cord injury in mice via suppressing the apoptosis and inflammatory response through HMGB1/TLR4/NF-κB pathway. — PubMed · 2020 · Journal Article
- Zinc promotes functional recovery after spinal cord injury by activating Nrf2/HO-1 defense pathway and inhibiting inflammation of NLRP3 in nerve cells. — PubMed · 2020 · Journal Article
- Acute upregulation of bone morphogenetic protein-4 regulates endogenous cell response and promotes cell death in spinal cord injury. — PubMed · 2020 · Journal Article
- EDNRB Reverses Methylprednisolone-Mediated Decrease in Neural Progenitor Cell Viability via Regulating PI3K/Akt Pathway and lncRNA Expression. — PubMed · 2020 · Journal Article
- Protective effect of D-pinitol on the experimental spinal cord injury in rats. — PubMed · 2020 · Journal Article
- Research on the Effects of Levetiracetam in Spinal Cord Injury Model in Rats: An Experimental Study. — PubMed · 2020 · Journal Article
- Triptolide improves spinal cord injury by promoting autophagy and inhibiting apoptosis. — PubMed · 2020 · Journal Article
- Tubular scaffold with microchannels and an H-shaped lumen loaded with bone marrow stromal cells promotes neuroregeneration and inhibits apoptosis after spinal cord injury. — PubMed · 2020 · Journal Article
- Macrophage MSR1 promotes the formation of foamy macrophage and neuronal apoptosis after spinal cord injury. — PubMed · 2020 · Journal Article
- Liraglutide provides neuroprotection by regulating autophagy through the AMPK-FOXO3 signaling pathway in a spinal contusion injury rat model. — PubMed · 2020 · Journal Article
- L1 Cell Adhesion Molecule Overexpression Down Regulates Phosphacan and Up Regulates Structural Plasticity-Related Genes Rostral and Caudal to the Complete Spinal Cord Transection. — PubMed · 2020 · Journal Article
- Melatonin exerts neuroprotective effects by attenuating astro- and microgliosis and suppressing inflammatory response following spinal cord injury. — PubMed · 2020 · Journal Article
- Scar Tissue-Targeting Polymer Micelle for Spinal Cord Injury Treatment. — PubMed · 2020 · Journal Article
Where this was looked for, and when
The latest collection walk and the accumulated shelf have different scopes. A zero applies only to that source query and its date window; older records may remain on the shelf. It does not mean no research exists.
| ClinicalTrials.gov | latest collection walk returned no records | asked on 2026-10-05 Collection window: 2026-09-16 – 2026-10-05 | matched in this collection walk 0 · accumulated records across collection walks 6 · still to fetch in this walk 0 | aim: every record matching this question |
|---|---|---|---|---|
| Crossref | asked, and it answered | asked on 2026-09-16 Collection window: all dates before the end date – 2026-09-16 | matched in this collection walk 1230843 · accumulated records across collection walks 50 | aim: a sample of the most relevant records. This source ranks a bag of words, so its own total is the size of the corpus that shares some of them, never a set still owed. |
| PubMed | asked, and it answered | asked on 2026-09-17 Collection window: all dates before the end date – 2026-09-17 | matched in this collection walk 3744 · accumulated records across collection walks 3744 · still to fetch in this walk 0 | aim: every record matching this question |
The question asked
- ClinicalTrials.gov
("neuroprotection" OR "secondary injury") - Crossref
spinal cord injury neuroprotection secondary injury - PubMed
("Spinal Cord Injuries"[MeSH Terms] OR "spinal cord injury"[Title/Abstract] OR "spinal cord injuries"[Title/Abstract] OR "spinal cord trauma"[Title/Abstract]) AND ("Neuroprotection"[MeSH Terms] OR "Neuroprotective Agents"[MeSH Terms] OR "neuroprotection"[Title/Abstract] OR "secondary injury"[Title/Abstract])