A subject this map covers
Neuroprotection
What belongs here
Attempts to stop the second, delayed wave of damage in the first hours and days.
What does not belong here, however close it looks
Restoring function lost months earlier is repair, not neuroprotection.
What has been looked at
Counted from what the sources catalogue, not from reading the work. It says how much exists and over what span of years — never what any of it found.
- Registered or indexed as work in people: 1169 records · 1978–2027
- Indexed as work in animals: 1885 records · 1977–2026
- Indexed as laboratory work: 80 records · 1996–2026
- The source has not said who or what was studied: 572 records · 1991–2026
- Nobody has yet checked any of this against its original for this map, so none of it is on the checked shelf.
Checked
Records a person has read against the original and published into this map. These carry measurements, evidence states and a place on the ladder.
Nobody has checked a record on this subject yet.
Checking is done by a person, one record at a time, and this subject has not reached the queue yet. The shelf below is what the sources hold in the meantime; it has not been read by anybody.
Found in the scientific sources, not yet checked
Titles and identifiers as the sources publish them. Nobody here has read these papers, and nothing on this shelf is a result, a recommendation or evidence that anything works. Each line opens the original.
3706 records
This grouping is the source's own cataloguing, not a reading of the paper. It says where a record was filed, not what it found.
Registered or indexed as work in people
- The Utility of Metabolomics in Spinal Cord Injury: Opportunities for Biomarker Discovery and Neuroprotection. — PubMed · 2025 · Journal Article
- Effect of blood pressure threshold on adverse outcomes in patients with acute spinal cord injury: a systematic review and meta-analysis. — PubMed · 2025 · Journal Article
- Effect of Low-dose Methylprednisolone in Promoting Neurological Function Recovery After Spinal Cord Injury: Clinical and Animal Studies. — PubMed · 2025 · Journal Article
- Design and protocol for the decompression-plus trial: a phase 1 clinical study of dorsal myelotomy and expansive duroplasty with or without autologous nerve grafting in acute traumatic spinal cord injury. — PubMed · 2025 · Clinical Trial Protocol
- The neuroprotective role of riluzole in spinal cord injury: a systematic review and meta-analysis. — PubMed · 2025 · Journal Article
- Spinal Cord Injury and Ageing: The Role of Chronic Neuroinflammation. — PubMed · 2025 · Journal Article
- Therapeutic potential of flavonoids in neuroprotection: brain and spinal cord injury focus. — PubMed · 2025 · Journal Article
- Chrysin's anti-inflammatory action in the central nervous system: A scoping review and an evidence-gap mapping of its mechanisms. — PubMed · 2025 · Journal Article
- Advanced Therapeutic Approaches Based on Small Extracellular Vehicles (sEVs) For the Regeneration of Spinal Cord Injuries. — PubMed · 2025 · Journal Article
- Exosomes: a promising microenvironment modulator for spinal cord injury treatment. — PubMed · 2025 · Journal Article
- Neuroprotective Riluzole-Releasing Electrospun Implants for Spinal Cord Injury. — PubMed · 2025 · Journal Article
- Navigating the complexities of spinal cord injury: an overview of pathology, treatment strategies and clinical trials. — PubMed · 2025 · Journal Article
- Unlocking the neuroprotective potential of peptide nucleic acids 5 (PNA5) in neurological diseases: molecular mechanisms to therapeutic approaches. — PubMed · 2025 · Journal Article
- Rewiring the Spine-Cutting-Edge Stem Cell Therapies for Spinal Cord Repair. — PubMed · 2025 · Journal Article
- Antioxidant nanozymes: current status and future perspectives in spinal cord injury treatments. — PubMed · 2025 · Journal Article
- Understanding recurrent pressure injuries: A scoping review of current research and risk factors. — PubMed · 2025 · Journal Article
- Advances in the Treatment of Spinal Cord Injury with Nanozymes. — PubMed · 2025 · Journal Article
- Pre-treated mesenchymal stem cell-derived exosomes: A new perspective for accelerating spinal cord injury repair. — PubMed · 2025 · Journal Article
- Modeling Spinal Cord Injury in a Dish with Hyperosmotic Stress: Population-Specific Effects and the Modulatory Role of Mesenchymal Stromal Cell Secretome. — PubMed · 2025 · Journal Article
- A review study on the effect of zinc on oxidative stress-related neurological disorders. — PubMed · 2025 · Journal Article
- Human Amniotic Epithelial Stem Cells Promote Functional Recovery After Spinal Cord Injury In Rats By Regulating The Polarization Of Macrophages. — PubMed · 2025 · Journal Article
- Therapeutic strategies that modulate the acute phase of secondary spinal cord injury scarring and inflammation and improve injury outcomes. — PubMed · 2025 · Journal Article
- Neurological Emergency Treatment Strategy: A Neuron-Targeted Regulation System for Reactive Oxygen Species Metabolism through Ferroptosis Modulation. — PubMed · 2025 · Journal Article
- 50 years of methylprednisolone application in spinal cord injury: a bibliometric analysis. — PubMed · 2025 · Journal Article
- Multi-omics uncovers immune-modulatory molecules in plasma contributing to resistance exercise-ameliorated locomotor disability after incomplete spinal cord injury. — PubMed · 2025 · Journal Article
- Mechanism of effect and therapeutic potential of NLRP3 inflammasome in spinal cord injury. — PubMed · 2025 · Journal Article
- Nrf2 Signaling Pathway: Focus on Oxidative Stress in Spinal Cord Injury. — PubMed · 2025 · Journal Article
- Sirtuin1 in Spinal Cord Injury: Regulatory Mechanisms, Microenvironment Remodeling and Therapeutic Potential. — PubMed · 2025 · Journal Article
- Total and Free Zinc Dynamics as Biomarkers for Neurological Impairment in Traumatic Spinal Cord Injury. — PubMed · 2025 · Journal Article
- Exploring Ubiquitination in Spinal Cord Injury Therapy: Multifaceted Targets and Promising Strategies. — PubMed · 2025 · Journal Article
- Stem Cell-Derived Extracellular Vesicle-Mediated Therapeutic Signaling in Spinal Cord Injury. — PubMed · 2025 · Journal Article
- Exploring the Effectiveness and Potential Pharmacological Mechanism of Minocycline for Spinal Cord Injury through Meta-Analysis and Network Pharmacology. — PubMed · 2025 · Journal Article
- MAPK signaling pathway in spinal cord injury: Mechanisms and therapeutic potential. — PubMed · 2025 · Journal Article
- Unraveling the complexity of microglial responses in traumatic brain and spinal cord injury. — PubMed · 2025 · Journal Article
- [Progress of researches on acupuncture treatment of spinal cord injury by regulating programmed cell death]. — PubMed · 2024 · Journal Article
- TET3-facilitated differentiation of human umbilical cord mesenchymal stem cells into oligodendrocyte precursor cells for spinal cord injury recovery. — PubMed · 2024 · Journal Article
- Nanoparticle Strategies for Treating CNS Disorders: A Comprehensive Review of Drug Delivery and Theranostic Applications. — PubMed · 2024 · Journal Article
- Advance in hyperbaric oxygen therapy in spinal cord injury. — PubMed · 2024 · Journal Article
- Conductive, injectable hydrogel equipped with tetramethylpyrazine regulates ferritinophagy and promotes spinal cord injury repair. — PubMed · 2024 · Journal Article
- FGF20 promotes spinal cord injury repair by inhibiting the formation of necrotic corpuscle P-MLKL/P-RIP1/P-RIP3 in neurons. — PubMed · 2024 · Journal Article
- Saffron and its major constituents against neurodegenerative diseases: A mechanistic review. — PubMed · 2024 · Journal Article
- Spinal cord neural stem cells derived from human embryonic stem cells promote synapse regeneration and remyelination in spinal cord injury model rats. — PubMed · 2024 · Journal Article
- The macrophage migration inhibitory factor/CD74 axis in traumatic spinal cord injury: lessons learned from animal and human studies. — PubMed · 2024 · Journal Article
- Identification of a New Role of miR-199a-5p as Factor Implied in Neuronal Damage: Decreasing the Expression of Its Target X-Linked Anti-Apoptotic Protein (XIAP) After SCI. — PubMed · 2024 · Journal Article
- The Yin and Yang of Microglia-Derived Extracellular Vesicles in CNS Injury and Diseases. — PubMed · 2024 · Journal Article
- Beneficial Effects of Human Schwann Cell-Derived Exosomes in Mitigating Secondary Damage After Penetrating Ballistic-Like Brain Injury. — PubMed · 2024 · Journal Article
- Cerebrospinal fluid drain placement and comprehensive strategies for spinal cord protection in open thoracoabdominal aortic aneurysm repair. — PubMed · 2024 · Journal Article
- Ferroptosis in the neurovascular unit after spinal cord injury. — PubMed · 2024 · Journal Article
- Interleukin-6 in Spinal Cord Injury: Could Immunomodulation Replace Immunosuppression in the Management of Acute Traumatic Spinal Cord Injuries? — PubMed · 2024 · Journal Article
- Neuroprotection and mechanisms of ginsenosides in nervous system diseases: Progress and perspectives. — PubMed · 2024 · Journal Article
- Operative Timing in Cervical Spine Trauma. — PubMed · 2024 · Journal Article
- Pharmacologic Therapy for Spinal Cord Injury. — PubMed · 2024 · Journal Article
- The Two Faces of HDAC3: Neuroinflammation in Disease and Neuroprotection in Recovery. — PubMed · 2024 · Journal Article
- An Update on Spinal Cord Injury and Current Management. — PubMed · 2024 · Journal Article
- Advances in Novel Biomaterial-Based Strategies for Spinal Cord Injury Treatment. — PubMed · 2024 · Journal Article
- AMPA receptors play an important role in the biological consequences of spinal cord injury: Implications for AMPA receptor modulators for therapeutic benefit. — PubMed · 2024 · Journal Article
- Epigenetic modifications of inflammation in spinal cord injury. — PubMed · 2024 · Journal Article
- Research Progress on the Effects of Different Exercise Modes on the Secretion of Exerkines After Spinal Cord Injury. — PubMed · 2024 · Journal Article
- Exosomes as promising bioactive materials in the treatment of spinal cord injury. — PubMed · 2024 · Journal Article
- The Neutrophil-to-Lymphocyte Ratio in Patients with Spinal Cord Injury: A Narrative Review Study. — PubMed · 2024 · Journal Article
Where this was looked for, and when
The exact question each source was asked, the day it was asked, and what came back. A zero on this page is only honest if these are on it.
| ClinicalTrials.gov | asked, and it has nothing | asked on 2026-10-05 | the source found 0 · this programme has 6 · still to fetch 0 | aim: every record matching this question |
|---|---|---|---|---|
| Crossref | asked, and it answered | asked on 2026-09-16 | the source found 1230843 · this programme has 50 | aim: a sample of the most relevant records. This source ranks a bag of words, so its own total is the size of the corpus that shares some of them, never a set still owed. |
| PubMed | asked, and it answered | asked on 2026-09-17 | the source found 3744 · this programme has 3744 · still to fetch 0 | aim: every record matching this question |
The question asked
- ClinicalTrials.gov
("neuroprotection" OR "secondary injury") - Crossref
spinal cord injury neuroprotection secondary injury - PubMed
("Spinal Cord Injuries"[MeSH Terms] OR "spinal cord injury"[Title/Abstract] OR "spinal cord injuries"[Title/Abstract] OR "spinal cord trauma"[Title/Abstract]) AND ("Neuroprotection"[MeSH Terms] OR "Neuroprotective Agents"[MeSH Terms] OR "neuroprotection"[Title/Abstract] OR "secondary injury"[Title/Abstract])