A subject this map covers
Neuroprotection
What belongs here
Attempts to stop the second, delayed wave of damage in the first hours and days.
What does not belong here, however close it looks
Restoring function lost months earlier is repair, not neuroprotection.
What has been looked at
Counted from what the sources catalogue, not from reading the work. It says how much exists and over what span of years — never what any of it found.
- Registered or indexed as work in people: 1169 records · 1978–2027
- Indexed as work in animals: 1885 records · 1977–2026
- Indexed as laboratory work: 80 records · 1996–2026
- The source has not said who or what was studied: 572 records · 1991–2026
- Nobody has yet checked any of this against its original for this map, so none of it is on the checked shelf.
Checked
Records a person has read against the original and published into this map. These carry measurements, evidence states and a place on the ladder.
Nobody has checked a record on this subject yet.
Checking is done by a person, one record at a time, and this subject has not reached the queue yet. The shelf below is what the sources hold in the meantime; it has not been read by anybody.
Found in the scientific sources, not yet checked
Titles and identifiers as the sources publish them. Nobody here has read these papers, and nothing on this shelf is a result, a recommendation or evidence that anything works. Each line opens the original.
3706 records
This grouping is the source's own cataloguing, not a reading of the paper. It says where a record was filed, not what it found.
Registered or indexed as work in people
- Critical Care of Spinal Cord Injury. — PubMed · 2024 · Journal Article
- Mesenchymal Stem Cell-Induced Neuroprotection in Pediatric Neurological Diseases: Recent Update of Underlying Mechanisms and Clinical Utility. — PubMed · 2024 · Journal Article
- The role of nitric oxide and hydrogen sulfide in spinal cord injury: an updated review. — PubMed · 2024 · Journal Article
- Spatial multi-omics analysis of the microenvironment in traumatic spinal cord injury: a narrative review. — PubMed · 2024 · Journal Article
- Safety and potential effects of intrathecal injection of allogeneic human umbilical cord mesenchymal stem cell-derived exosomes in complete subacute spinal cord injury: a first-in-human, single-arm, open-label, phase I clinical trial. — PubMed · 2024 · Journal Article
- Letter to the editor: Systematic review on neuroprotective agents in spinal cord injury. — PubMed · 2024 · Letter
- Targeting NMDA receptors with an antagonist is a promising therapeutic strategy for treating neurological disorders. — PubMed · 2024 · Journal Article
- Self-Assembled Fibroblast Growth Factor Nanoparticles as a Therapeutic for Oxidant-Induced Neuronal and Skin Cell Injury. — PubMed · 2024 · Journal Article
- A marine-derived antioxidant astaxanthin as a potential neuroprotective and neurotherapeutic agent: A review of its efficacy on neurodegenerative conditions. — PubMed · 2024 · Journal Article
- Fisetin Promotes Functional Recovery after Spinal Cord Injury by Inhibiting Microglia/Macrophage M1 Polarization and JAK2/STAT3 Signaling Pathway. — PubMed · 2024 · Journal Article
- Neutralizing RGMa with Elezanumab Promotes Cerebroprotection and Recovery in Rabbit Middle Cerebral Artery Occlusion. — PubMed · 2024 · Journal Article
- S100A9 Induces Macrophage M2 Polarization and Immunomodulatory Role in the Lesion Site After Spinal Cord Injury in Rats. — PubMed · 2024 · Journal Article
- Mapping the landscape: A bibliometric perspective on autophagy in spinal cord injury. — PubMed · 2024 · Journal Article
- Ginsenoside-Rh2 Promotes Functional Recovery after Spinal Cord Injury by Enhancing TFEB-Mediated Autophagy. — PubMed · 2024 · Journal Article
- Clinical application and potential pluripotent effects of hepatocyte growth factor in spinal cord injury regeneration. — PubMed · 2024 · Journal Article
- Plant-derived bioactive compounds and their novel role in central nervous system disorder treatment via ATF4 targeting: A systematic literature review. — PubMed · 2024 · Journal Article
- Targeted Therapy of Spinal Cord Injury: Inhibition of Apoptosis Is a Promising Therapeutic Strategy. — PubMed · 2024 · Journal Article
- Therapeutic effects of exendin-4 on spinal cord injury via restoring autophagy function and decreasing necroptosis in neuron. — PubMed · 2024 · Journal Article
- Hydrogen Sulfide can Scavenge Free Radicals to Improve Spinal Cord Injury by Inhibiting the p38MAPK/mTOR/NF-κB Signaling Pathway. — PubMed · 2024 · Journal Article
- Recombinant fibroblast growth factor 4 ameliorates axonal regeneration and functional recovery in acute spinal cord injury through altering microglia/macrophage phenotype. — PubMed · 2024 · Journal Article
- Inflammatory response in traumatic brain and spinal cord injury: The role of XCL1-XCR1 axis and T cells. — PubMed · 2024 · Journal Article
- [Specialized Concepts for the Management of Severe Neurotrauma]. — PubMed · 2024 · Journal Article
- Traumatic Brain Injury and Traumatic Spinal Cord Injury. — PubMed · 2024 · Journal Article
- Unraveling the controversy: high-dose steroids in spinal cord injury. Forty years of inquiry. — PubMed · 2024 · Journal Article
- Recent advances in the application of gasotransmitters in spinal cord injury. — PubMed · 2024 · Journal Article
- Immunotherapy of M2 macrophage derived from exosome-based nanoparticles for spinal cord injury. — PubMed · 2024 · Journal Article
- Molars to Medicine: A Focused Review on the Pre-Clinical Investigation and Treatment of Secondary Degeneration following Spinal Cord Injury Using Dental Stem Cells. — PubMed · 2024 · Journal Article
- Advanced Magnetic Resonance Imaging Biomarkers of the Injured Spinal Cord: A Comparative Study of Imaging and Histology in Human Traumatic Spinal Cord Injury. — PubMed · 2024 · Journal Article
- The Molecular Biological Mechanism of Hydrogen Therapy and Its Application in Spinal Cord Injury. — PubMed · 2024 · Journal Article
- Spinal Decompression Plus Nerve Graft Implantation Following TSCI — ClinicalTrials.gov · 2024 · Interventional · Recruiting
- Functional Polyphenol-Based Nanoparticles Boosted the Neuroprotective Effect of Riluzole for Acute Spinal Cord Injury. — PubMed · 2024 · Journal Article
- ATF3 is a neuron-specific biomarker for spinal cord injury and ischaemic stroke. — PubMed · 2024 · Journal Article
- Exosomes Derived from Mesenchymal Stem Cells: Therapeutic Opportunities for Spinal Cord Injury. — PubMed · 2024 · Journal Article
- α-Gal Nanoparticles in CNS Trauma: II. Immunomodulation Following Spinal Cord Injury (SCI) Improves Functional Outcomes. — PubMed · 2024 · Journal Article
- An updated systematic review of neuroprotective agents in the treatment of spinal cord injury. — PubMed · 2024 · Systematic Review
- Modified ZIF-8 Nanoparticles for Targeted Metabolic Treatment of Acute Spinal Cord Injury. — PubMed · 2024 · Journal Article
- The Translation of Nanomedicines in the Contexts of Spinal Cord Injury and Repair. — PubMed · 2024 · Journal Article
- Astrocytes in Spinal Cord Injury: Current Opportunities and Prospects for Directional Polarization. — PubMed · 2024 · Journal Article
- Embryonic stem cells overexpressing high molecular weight FGF2 isoform enhance recovery of pre-ganglionic spinal root lesion in combination with fibrin biopolymer mediated root repair. — PubMed · 2024 · Journal Article
- The role of olfactory ensheathing cells in the repair of nerve injury. — PubMed · 2024 · Journal Article
- A Perspective on Hormonal Contraception Usage in Central Nervous System Injury. — PubMed · 2024 · Journal Article
- Exploring the mechanisms of kaempferol in neuroprotection: Implications for neurological disorders. — PubMed · 2024 · Journal Article
- Prognostic value of the systemic inflammatory index (SII) and systemic inflammatory response index (SIRI) in patients with traumatic spinal cord injury. — PubMed · 2024 · Journal Article
- Role of dendritic cells in spinal cord injury. — PubMed · 2024 · Journal Article
- The acute spinal cord injury microenvironment and its impact on the homing of mesenchymal stem cells. — PubMed · 2024 · Journal Article
- Do Pharmacological Treatments Act in Collaboration with Rehabilitation in Spinal Cord Injury Treatment? A Review of Preclinical Studies. — PubMed · 2024 · Journal Article
- Plasma GDNF levels in spinal dysraphism and its relation with neurological impairment in children: A point of care study. — PubMed · 2024 · Journal Article
- Research hotpots and frontier trends of neuroprotective effects of magnesium from 1999 to 2023: A bibliometric analysis. — PubMed · 2024 · Journal Article
- Traumatic Spinal Cord Injury. — PubMed · 2024 · Review
- hBcl2 overexpression in BMSCs enhances resistance to myelin debris-induced apoptosis and facilitates neuroprotection after spinal cord injury in rats. — PubMed · 2024 · Journal Article
- Activated Human Adipose Tissue Transplantation Promotes Sensorimotor Recovery after Acute Spinal Cord Contusion in Rats. — PubMed · 2024 · Journal Article
- Application and challenges of olfactory ensheathing cells in clinical trials of spinal cord injury. — PubMed · 2024 · Journal Article
- Exosome-mediated repair of spinal cord injury: a promising therapeutic strategy. — PubMed · 2024 · Journal Article
- GPNMB Modulates Autophagy to Enhance Functional Recovery After Spinal Cord Injury in Rats. — PubMed · 2024 · Journal Article
- Mechanically Activated Adipose Tissue as a Source for Novel Therapies in Neurological Disease/Injury. — PubMed · 2024 · Review
- Mechanism Study of Polydatin in Treating Spinal Cord Injury by Modulating Mitochondrial Membrane Potential Based on Network Pharmacology and Molecular Docking. — PubMed · 2024 · Journal Article
- Spinal cord injury: Olfactory ensheathing cell-based therapeutic strategies. — PubMed · 2024 · Journal Article
- Traumatic Human Spinal Cord Injury: Are Single Treatments Enough to Solve the Problem? — PubMed · 2024 · Journal Article
- Schwann Cell-Derived Exosomal Vesicles: A Promising Therapy for the Injured Spinal Cord. — PubMed · 2023 · Journal Article
- General Anesthesia Blocks Pain-Induced Hemorrhage and Locomotor Deficits After Spinal Cord Injury in Rats. — PubMed · 2023 · Journal Article
Where this was looked for, and when
The exact question each source was asked, the day it was asked, and what came back. A zero on this page is only honest if these are on it.
| ClinicalTrials.gov | asked, and it has nothing | asked on 2026-10-05 | the source found 0 · this programme has 6 · still to fetch 0 | aim: every record matching this question |
|---|---|---|---|---|
| Crossref | asked, and it answered | asked on 2026-09-16 | the source found 1230843 · this programme has 50 | aim: a sample of the most relevant records. This source ranks a bag of words, so its own total is the size of the corpus that shares some of them, never a set still owed. |
| PubMed | asked, and it answered | asked on 2026-09-17 | the source found 3744 · this programme has 3744 · still to fetch 0 | aim: every record matching this question |
The question asked
- ClinicalTrials.gov
("neuroprotection" OR "secondary injury") - Crossref
spinal cord injury neuroprotection secondary injury - PubMed
("Spinal Cord Injuries"[MeSH Terms] OR "spinal cord injury"[Title/Abstract] OR "spinal cord injuries"[Title/Abstract] OR "spinal cord trauma"[Title/Abstract]) AND ("Neuroprotection"[MeSH Terms] OR "Neuroprotective Agents"[MeSH Terms] OR "neuroprotection"[Title/Abstract] OR "secondary injury"[Title/Abstract])