A subject this map covers
Neuroprotection
What belongs here
Attempts to stop the second, delayed wave of damage in the first hours and days.
What does not belong here, however close it looks
Restoring function lost months earlier is repair, not neuroprotection.
What has been looked at
Counted from what the sources catalogue, not from reading the work. It says how much exists and over what span of years — never what any of it found.
- Registered or indexed as work in people: 1169 records · 1978–2027
- Indexed as work in animals: 1885 records · 1977–2026
- Indexed as laboratory work: 80 records · 1996–2026
- The source has not said who or what was studied: 572 records · 1991–2026
- No matching published catalogue records are linked above. Human-review status must be checked on the evidence itself.
Published in this map
Catalogue records matching this subject. Publication here does not establish human review, measured results or effectiveness. Open a record to inspect its sources and evidence.
No published catalogue records match this subject yet.
This is a result within this map, not a claim that no research exists. The source records below can help you continue searching.
Found in the scientific sources, not yet checked
Titles and identifiers as the sources publish them. Nobody here has read these papers, and nothing on this shelf is a result, a recommendation or evidence that anything works. Each line opens the original.
3706 records
This grouping is the source's own cataloguing, not a reading of the paper. It says where a record was filed, not what it found.
Indexed as work in animals
- Characterizing the Neuroprotective Effects of S/B Remedy (Scutellaria baicalensis Georgi and Bupleurum scorzonerifolfium Willd) in Spinal Cord Injury. — PubMed · 2019 · Journal Article
- Harpagide inhibits neuronal apoptosis and promotes axonal regeneration after spinal cord injury in rats by activating the Wnt/β-catenin signaling pathway. — PubMed · 2019 · Journal Article
- Macrolide derivatives reduce proinflammatory macrophage activation and macrophage-mediated neurotoxicity. — PubMed · 2019 · Journal Article
- Trehalose attenuates spinal cord injury through the regulation of oxidative stress, inflammation and GFAP expression in rats. — PubMed · 2019 · Journal Article
- Sustained interleukin-10 delivery reduces inflammation and improves motor function after spinal cord injury. — PubMed · 2019 · Journal Article
- Designing multifunctionalized selenium nanoparticles to reverse oxidative stress-induced spinal cord injury by attenuating ROS overproduction and mitochondria dysfunction. — PubMed · 2019 · Journal Article
- Lidocaine protects neurons of the spinal cord in an excitotoxicity model. — PubMed · 2019 · Journal Article
- Neuroprotection, Recovery of Function and Endogenous Neurogenesis in Traumatic Spinal Cord Injury Following Transplantation of Activated Adipose Tissue. — PubMed · 2019 · Journal Article
- Astragoloside IV Loaded Polycaprolactone Membrane Repairs Blood Spinal Cord Barrier and Recovers Spinal Cord Function in Traumatic Spinal Cord Injury. — PubMed · 2019 · Journal Article
- Expression of miR-210 mediated by adeno-associated virus performed neuroprotective effects on a rat model of acute spinal cord injury. — PubMed · 2019 · Journal Article
- MicroRNA‑124 improves functional recovery and suppresses Bax‑dependent apoptosis in rats following spinal cord injury. — PubMed · 2019 · Journal Article
- Progesterone effects on oligodendrocyte differentiation in injured spinal cord. — PubMed · 2019 · Journal Article
- Activating Adiponectin Signaling with Exogenous AdipoRon Reduces Myelin Lipid Accumulation and Suppresses Macrophage Recruitment after Spinal Cord Injury. — PubMed · 2019 · Journal Article
- Ferroptosis inhibitor SRS 16-86 attenuates ferroptosis and promotes functional recovery in contusion spinal cord injury. — PubMed · 2019 · Journal Article
- Resveratrol treatment of spinal cord injury in rat model. — PubMed · 2019 · Journal Article
- Polysialic-Acid-Based Micelles Promote Neural Regeneration in Spinal Cord Injury Therapy. — PubMed · 2019 · Journal Article
- Cell viability in three ex vivo rat models of spinal cord injury. — PubMed · 2019 · Comparative Study
- Intravenous Infusion of Mesenchymal Stem Cells Alters Motor Cortex Gene Expression in a Rat Model of Acute Spinal Cord Injury. — PubMed · 2019 · Journal Article
- Reducing age-dependent monocyte-derived macrophage activation contributes to the therapeutic efficacy of NADPH oxidase inhibition in spinal cord injury. — PubMed · 2019 · Journal Article
- An anti-inflammatory peptide and brain-derived neurotrophic factor-modified hyaluronan-methylcellulose hydrogel promotes nerve regeneration in rats with spinal cord injury. — PubMed · 2019 · Journal Article
- Polydatin attenuates spinal cord injury in rats by inhibiting oxidative stress and microglia apoptosis via Nrf2/HO-1 pathway. — PubMed · 2019 · Journal Article
- Buyang huanwu decoction combined with BMSCs transplantation promotes recovery after spinal cord injury by rescuing axotomized red nucleus neurons. — PubMed · 2019 · Journal Article
- Can Quercetin be an Option for Treatment of Spinal Cord Injury? An Experimental Study. — PubMed · 2019 · Journal Article
- Effect of Selenium Nanoparticle Supplementation on Tissue Inflammation, Blood Cell Count, and IGF-1 Levels in Spinal Cord Injury-Induced Rats. — PubMed · 2019 · Journal Article
- Engaging pain fibers after a spinal cord injury fosters hemorrhage and expands the area of secondary injury. — PubMed · 2019 · Journal Article
- Evaluation of the effects of erythropoietin and interleukin-6 in rats submitted to acute spinal cord injury. — PubMed · 2019 · Journal Article
- Evaluation of the neuroprotective effects of anti-inflammatory drugs in experimental spinal cord damage. — PubMed · 2019 · Journal Article
- Icariin Inhibits Endoplasmic Reticulum Stress-induced Neuronal Apoptosis after Spinal Cord Injury through Modulating the PI3K/AKT Signaling Pathway. — PubMed · 2019 · Journal Article
- Myxoma virus derived immune modulating proteins, M-T7 and Serp-1, reduce early inflammation after spinal cord injury in the rat model. — PubMed · 2019 · Journal Article
- Neuroprotective effects of allopurinol on spinal cord injury in rats: a biochemical and immunohistochemical study. — PubMed · 2019 · Journal Article
- Neuroprotective effects of a potent bradykinin B2 receptor antagonist HOE-140 on microvascular permeability, blood flow disturbances, edema formation, cell injury and nitric oxide synthase upregulation following trauma to the spinal cord. — PubMed · 2019 · Journal Article
- Neuroprotective Effects of Lacosamide in Experimental Traumatic Spinal Cord Injury in Rats. — PubMed · 2019 · Journal Article
- Neuroprotective potential of Spirulina platensis on lesioned spinal cord corticospinal tract under experimental conditions in rat models. — PubMed · 2019 · Journal Article
- Potentiation of spinal cord conduction and neuroprotection following nanodelivery of DL-3-n-butylphthalide in titanium implanted nanomaterial in a focal spinal cord injury induced functional outcome, blood-spinal cord barrier breakdown and edema formation. — PubMed · 2019 · Journal Article
- Vanillin ameliorates changes in HIF-1α expression and neuronal apoptosis in a rat model of spinal cord injury. — PubMed · 2019 · Journal Article The source marks this record as retracted.
- Minocycline Reduces the Severity of Autonomic Dysreflexia after Experimental Spinal Cord Injury. — PubMed · 2018 · Journal Article
- Neuroprotection by Paeoniflorin against Nuclear Factor Kappa B-Induced Neuroinflammation on Spinal Cord Injury. — PubMed · 2018 · Journal Article
- AMP-activated protein kinase-dependent induction of autophagy by erythropoietin protects against spinal cord injury in rats. — PubMed · 2018 · Journal Article
- Ginsenoside Rb1 protects against spinal cord ischemia-reperfusion injury in rats by downregulating the Bax/Bcl-2 ratio and caspase-3 and p-Ask-1 levels. — PubMed · 2018 · Journal Article
- Internal decompression of the acutely contused spinal cord: Differential effects of irrigation only versus biodegradable scaffold implantation. — PubMed · 2018 · Journal Article
- Neuroprotective Effects of Vigabatrin on Spinal Cord Ischemia-Reperfusion Injury. — PubMed · 2018 · Journal Article
- Identification of differentially expressed proteins in rats with spinal cord injury during the transitional phase using an iTRAQ-based quantitative analysis. — PubMed · 2018 · Journal Article
- [Neuroprotective effect of icariin on spinal cord injury in rats]. — PubMed · 2018 · Journal Article
- Locomotor Training Promotes Time-dependent Functional Recovery after Experimental Spinal Cord Contusion. — PubMed · 2018 · Journal Article
- 3-Iodothyronamine Acting through an Anti-Apoptotic Mechanism Is Neuroprotective Against Spinal Cord Injury in Rats. — PubMed · 2018 · Journal Article
- Blood Glutamate Scavenger as a Novel Neuroprotective Treatment in Spinal Cord Injury. — PubMed · 2018 · Journal Article
- Bromodomain and extraterminal domain-containing protein inhibition attenuates acute inflammation after spinal cord injury. — PubMed · 2018 · Journal Article
- Protective effect of docosahexaenoic acid on lipotoxicity-mediated cell death in Schwann cells: Implication of PI3K/AKT and mTORC2 pathways. — PubMed · 2018 · Journal Article
- Conotoxin MVIIA improves cell viability and antioxidant system after spinal cord injury in rats. — PubMed · 2018 · Journal Article
- Astrocyte Autophagy Flux Protects Neurons Against Oxygen-Glucose Deprivation and Ischemic/Reperfusion Injury. — PubMed · 2018 · Journal Article
- CD200 modulates spinal cord injury neuroinflammation and outcome through CD200R1. — PubMed · 2018 · Journal Article
- Contrast-enhanced ultrasound to visualize hemodynamic changes after rodent spinal cord injury. — PubMed · 2018 · Journal Article
- Neuroprotection and immunomodulation following intraspinal axotomy of motoneurons by treatment with adult mesenchymal stem cells. — PubMed · 2018 · Journal Article
- Amelioration of spinal cord injury in rats by blocking peroxynitrite/calpain activity. — PubMed · 2018 · Journal Article
- Novel multi-drug delivery hydrogel using scar-homing liposomes improves spinal cord injury repair. — PubMed · 2018 · Journal Article
- Diosgenin Glucoside Protects against Spinal Cord Injury by Regulating Autophagy and Alleviating Apoptosis. — PubMed · 2018 · Journal Article
- AKR1B1 Upregulation Contributes to Neuroinflammation and Astrocytes Proliferation by Regulating the Energy Metabolism in Rat Spinal Cord Injury. — PubMed · 2018 · Journal Article
- Combined effects of rat Schwann cells and 17β-estradiol in a spinal cord injury model. — PubMed · 2018 · Journal Article
- Effects of Mitochondrial Transplantation on Bioenergetics, Cellular Incorporation, and Functional Recovery after Spinal Cord Injury. — PubMed · 2018 · Journal Article
- FNDC5 expression in Purkinje neurons of adult male rats with acute spinal cord injury following treatment with methylprednisolone. — PubMed · 2018 · Journal Article
Where this was looked for, and when
The latest collection walk and the accumulated shelf have different scopes. A zero applies only to that source query and its date window; older records may remain on the shelf. It does not mean no research exists.
| ClinicalTrials.gov | latest collection walk returned no records | asked on 2026-10-05 Collection window: 2026-09-16 – 2026-10-05 | matched in this collection walk 0 · accumulated records across collection walks 6 · still to fetch in this walk 0 | aim: every record matching this question |
|---|---|---|---|---|
| Crossref | asked, and it answered | asked on 2026-09-16 Collection window: all dates before the end date – 2026-09-16 | matched in this collection walk 1230843 · accumulated records across collection walks 50 | aim: a sample of the most relevant records. This source ranks a bag of words, so its own total is the size of the corpus that shares some of them, never a set still owed. |
| PubMed | asked, and it answered | asked on 2026-09-17 Collection window: all dates before the end date – 2026-09-17 | matched in this collection walk 3744 · accumulated records across collection walks 3744 · still to fetch in this walk 0 | aim: every record matching this question |
The question asked
- ClinicalTrials.gov
("neuroprotection" OR "secondary injury") - Crossref
spinal cord injury neuroprotection secondary injury - PubMed
("Spinal Cord Injuries"[MeSH Terms] OR "spinal cord injury"[Title/Abstract] OR "spinal cord injuries"[Title/Abstract] OR "spinal cord trauma"[Title/Abstract]) AND ("Neuroprotection"[MeSH Terms] OR "Neuroprotective Agents"[MeSH Terms] OR "neuroprotection"[Title/Abstract] OR "secondary injury"[Title/Abstract])