A subject this map covers
Neuroprotection
What belongs here
Attempts to stop the second, delayed wave of damage in the first hours and days.
What does not belong here, however close it looks
Restoring function lost months earlier is repair, not neuroprotection.
What has been looked at
Counted from what the sources catalogue, not from reading the work. It says how much exists and over what span of years — never what any of it found.
- Registered or indexed as work in people: 1169 records · 1978–2027
- Indexed as work in animals: 1885 records · 1977–2026
- Indexed as laboratory work: 80 records · 1996–2026
- The source has not said who or what was studied: 572 records · 1991–2026
- No matching published catalogue records are linked above. Human-review status must be checked on the evidence itself.
Published in this map
Catalogue records matching this subject. Publication here does not establish human review, measured results or effectiveness. Open a record to inspect its sources and evidence.
No published catalogue records match this subject yet.
This is a result within this map, not a claim that no research exists. The source records below can help you continue searching.
Found in the scientific sources, not yet checked
Titles and identifiers as the sources publish them. Nobody here has read these papers, and nothing on this shelf is a result, a recommendation or evidence that anything works. Each line opens the original.
3706 records
This grouping is the source's own cataloguing, not a reading of the paper. It says where a record was filed, not what it found.
Indexed as work in animals
- An In Vivo Duo-color Method for Imaging Vascular Dynamics Following Contusive Spinal Cord Injury. — PubMed · 2017 · Journal Article
- Ketogenic Metabolism Inhibits Histone Deacetylase (HDAC) and Reduces Oxidative Stress After Spinal Cord Injury in Rats. — PubMed · 2017 · Journal Article
- Crocetin Potentiates Neurite Growth in Hippocampal Neurons and Facilitates Functional Recovery in Rats with Spinal Cord Injury. — PubMed · 2017 · Journal Article
- Geraniol promotes functional recovery and attenuates neuropathic pain in rats with spinal cord injury. — PubMed · 2017 · Journal Article
- Intraspinal TLR4 activation promotes iron storage but does not protect neurons or oligodendrocytes from progressive iron-mediated damage. — PubMed · 2017 · Journal Article
- Localized delivery of methylprednisolone sodium succinate with polymeric nanoparticles in experimental injured spinal cord model. — PubMed · 2017 · Journal Article
- Metformin ameliorates BSCB disruption by inhibiting neutrophil infiltration and MMP-9 expression but not direct TJ proteins expression regulation. — PubMed · 2017 · Journal Article
- Necrostatin-1 Mitigates Endoplasmic Reticulum Stress After Spinal Cord Injury. — PubMed · 2017 · Journal Article
- The neuroprotective effect of N-acetylcysteine in spinal cord-injured rats. — PubMed · 2017 · Journal Article
- Withaferin A protects against spinal cord injury by inhibiting apoptosis and inflammation in mice. — PubMed · 2017 · Journal Article
- Anterior chamber associated immune deviation used as a neuroprotective strategy in rats with spinal cord injury. — PubMed · 2017 · Journal Article
- Maresin 1 Promotes Inflammatory Resolution, Neuroprotection, and Functional Neurological Recovery After Spinal Cord Injury. — PubMed · 2017 · Journal Article
- A green tea polyphenol epigallocatechin-3-gallate enhances neuroregeneration after spinal cord injury by altering levels of inflammatory cytokines. — PubMed · 2017 · Journal Article
- Effective improvement of the neuroprotective activity after spinal cord injury by synergistic effect of glucocorticoid with biodegradable amphipathic nanomicelles. — PubMed · 2017 · Journal Article
- Fumaric Acid Esters Attenuate Secondary Degeneration after Spinal Cord Injury. — PubMed · 2017 · Journal Article
- Lithium Chloride Facilitates Autophagy Following Spinal Cord Injury via ERK-dependent Pathway. — PubMed · 2017 · Journal Article
- Metformin Protects against Experimental Acrylamide Neuropathy in Rats. — PubMed · 2017 · Journal Article
- Myricitrin decreases traumatic injury of the spinal cord and exhibits antioxidant and anti‑inflammatory activities in a rat model via inhibition of COX‑2, TGF‑β1, p53 and elevation of Bcl‑2/Bax signaling pathway. — PubMed · 2017 · Journal Article
- RhoA/Rho Kinase Mediates Neuronal Death Through Regulating cPLA(2) Activation. — PubMed · 2017 · Journal Article
- Palm vitamin E reduces locomotor dysfunction and morphological changes induced by spinal cord injury and protects against oxidative damage. — PubMed · 2017 · Journal Article
- Comparative effects of vitamin D and methylprednisolone against ischemia/reperfusion injury of rabbit spinal cords. — PubMed · 2017 · Comparative Study
- MiR-136 controls neurocytes apoptosis by regulating Tissue Inhibitor of Metalloproteinases-3 in spinal cord ischemic injury. — PubMed · 2017 · Journal Article
- Mst-1 deficiency promotes post-traumatic spinal motor neuron survival via enhancement of autophagy flux. — PubMed · 2017 · Journal Article
- Neuroprotective effects of pregabalin in a rat model of intracisternal facial nerve avulsion. — PubMed · 2017 · Journal Article
- Targeting Enolase in Reducing Secondary Damage in Acute Spinal Cord Injury in Rats. — PubMed · 2017 · Journal Article
- Thermosensitive heparin-poloxamer hydrogels enhance the effects of GDNF on neuronal circuit remodeling and neuroprotection after spinal cord injury. — PubMed · 2017 · Journal Article
- N-Palmitoylethanolamine-Oxazoline as a New Therapeutic Strategy to Control Neuroinflammation: Neuroprotective Effects in Experimental Models of Spinal Cord and Brain Injury. — PubMed · 2017 · Journal Article
- The synthetic cannabinoid WIN55212-2 ameliorates traumatic spinal cord injury via inhibition of GAPDH/Siah1 in a CB2-receptor dependent manner. — PubMed · 2017 · Journal Article
- Investigation of efficacy of treatment in spinal cord injury: Erythropoietin versus methylprednisolone. — PubMed · 2017 · Comparative Study
- Phosphodiesterase inhibitor ameliorates neuronal injury in spinal cord ischemia/reperfusion injured rat model. — PubMed · 2017 · Journal Article
- The effectiveness of the anti-CD11d treatment is reduced in rat models of spinal cord injury that produce significant levels of intraspinal hemorrhage. — PubMed · 2017 · Journal Article
- Compression Decreases Anatomical and Functional Recovery and Alters Inflammation after Contusive Spinal Cord Injury. — PubMed · 2017 · Journal Article
- Polyethylene glycol-induced motor recovery after total spinal transection in rats. — PubMed · 2017 · Journal Article
- The effects of dexmedetomidine pretreatment on the pro- and anti-inflammation systems after spinal cord injury in rats. — PubMed · 2017 · Journal Article
- The toll-like receptor 2 agonist Pam3CSK4 is neuroprotective after spinal cord injury. — PubMed · 2017 · Journal Article
- [Neuroprotective effects and mechanism of saikosaponin A on acute spinal cord injury in rats]. — PubMed · 2017 · Journal Article
- Microtubule stabilization promoted axonal regeneration and functional recovery after spinal root avulsion. — PubMed · 2017 · Journal Article
- Neuregulin-1 positively modulates glial response and improves neurological recovery following traumatic spinal cord injury. — PubMed · 2017 · Journal Article
- Pioglitazone treatment following spinal cord injury maintains acute mitochondrial integrity and increases chronic tissue sparing and functional recovery. — PubMed · 2017 · Journal Article
- Neuroprotective effects of astaxanthin in a rat model of spinal cord injury. — PubMed · 2017 · Journal Article
- Natural IgM antibodies that bind neoepitopes exposed as a result of spinal cord injury , drive secondary injury by activating complement. — PubMed · 2017 · Journal Article
- Feasibility of Diffusion Tensor Imaging for Assessing Functional Recovery in Rats with Olfactory Ensheathing Cell Transplantation After Contusive Spinal Cord Injury (SCI). — PubMed · 2017 · Journal Article
- The Alternative Receptor for Complement Component 5a, C5aR2, Conveys Neuroprotection in Traumatic Spinal Cord Injury. — PubMed · 2017 · Journal Article
- Dimercaprol is an acrolein scavenger that mitigates acrolein-mediated PC-12 cells toxicity and reduces acrolein in rat following spinal cord injury. — PubMed · 2017 · Journal Article
- E6020, a synthetic TLR4 agonist, accelerates myelin debris clearance, Schwann cell infiltration, and remyelination in the rat spinal cord. — PubMed · 2017 · Journal Article
- PPAR-γ agonist rosiglitazone reduces autophagy and promotes functional recovery in experimental traumaticspinal cord injury. — PubMed · 2017 · Journal Article
- A Single Dose of Docosahexaenoic Acid Increases the Functional Recovery Promoted by Rehabilitation after Cervical Spinal Cord Injury in the Rat. — PubMed · 2017 · Journal Article
- KU0063794, a Dual mTORC1 and mTORC2 Inhibitor, Reduces Neural Tissue Damage and Locomotor Impairment After Spinal Cord Injury in Mice. — PubMed · 2017 · Journal Article
- Resveratrol protects against spinal cord injury by activating autophagy and inhibiting apoptosis mediated by the SIRT1/AMPK signaling pathway. — PubMed · 2017 · Journal Article
- Sophorolipid Butyl Ester Diacetate Does Not Affect Macrophage Polarization but Enhances Astrocytic Glial Fibrillary Acidic Protein Expression at Micromolar Concentrations in Vitro. — PubMed · 2017 · Journal Article
- Creation of an intramedullary cavity by hemorrhagic necrosis removal 24 h after spinal cord contusion in rats for eventual intralesional implantation of restorative materials. — PubMed · 2017 · Journal Article
- Low-level laser facilitates alternatively activated macrophage/microglia polarization and promotes functional recovery after crush spinal cord injury in rats. — PubMed · 2017 · Journal Article
- Deficiency of TREK-1 potassium channel exacerbates secondary injury following spinal cord injury in mice. — PubMed · 2017 · Journal Article
- Functional and structural changes of the urinary bladder following spinal cord injury; treatment with alpha lipoic acid. — PubMed · 2017 · Journal Article
- In vivo two-photon imaging reveals a role of progesterone in reducing axonal dieback after spinal cord injury in mice. — PubMed · 2017 · Journal Article
- Spinal cord injury effectively ameliorated by neuroprotective effects of rosmarinic acid. — PubMed · 2017 · Journal Article
- Immunomodulatory and neuroprotective effect of cryopreserved allogeneic mesenchymal stem cells on spinal cord injury in rats. — PubMed · 2017 · Journal Article
- An Agonist of the Protective Factor SIRT1 Improves Functional Recovery and Promotes Neuronal Survival by Attenuating Inflammation after Spinal Cord Injury. — PubMed · 2017 · Journal Article
- Electroacupuncture pretreatment attenuates spinal cord ischemia-reperfusion injury via inhibition of high-mobility group box 1 production in a LXA(4) receptor-dependent manner. — PubMed · 2017 · Journal Article
- Pain Input Impairs Recovery after Spinal Cord Injury: Treatment with Lidocaine. — PubMed · 2017 · Journal Article
Where this was looked for, and when
The latest collection walk and the accumulated shelf have different scopes. A zero applies only to that source query and its date window; older records may remain on the shelf. It does not mean no research exists.
| ClinicalTrials.gov | latest collection walk returned no records | asked on 2026-10-05 Collection window: 2026-09-16 – 2026-10-05 | matched in this collection walk 0 · accumulated records across collection walks 6 · still to fetch in this walk 0 | aim: every record matching this question |
|---|---|---|---|---|
| Crossref | asked, and it answered | asked on 2026-09-16 Collection window: all dates before the end date – 2026-09-16 | matched in this collection walk 1230843 · accumulated records across collection walks 50 | aim: a sample of the most relevant records. This source ranks a bag of words, so its own total is the size of the corpus that shares some of them, never a set still owed. |
| PubMed | asked, and it answered | asked on 2026-09-17 Collection window: all dates before the end date – 2026-09-17 | matched in this collection walk 3744 · accumulated records across collection walks 3744 · still to fetch in this walk 0 | aim: every record matching this question |
The question asked
- ClinicalTrials.gov
("neuroprotection" OR "secondary injury") - Crossref
spinal cord injury neuroprotection secondary injury - PubMed
("Spinal Cord Injuries"[MeSH Terms] OR "spinal cord injury"[Title/Abstract] OR "spinal cord injuries"[Title/Abstract] OR "spinal cord trauma"[Title/Abstract]) AND ("Neuroprotection"[MeSH Terms] OR "Neuroprotective Agents"[MeSH Terms] OR "neuroprotection"[Title/Abstract] OR "secondary injury"[Title/Abstract])