A subject this map covers
Neuroprotection
What belongs here
Attempts to stop the second, delayed wave of damage in the first hours and days.
What does not belong here, however close it looks
Restoring function lost months earlier is repair, not neuroprotection.
What has been looked at
Counted from what the sources catalogue, not from reading the work. It says how much exists and over what span of years — never what any of it found.
- Registered or indexed as work in people: 1169 records · 1978–2027
- Indexed as work in animals: 1885 records · 1977–2026
- Indexed as laboratory work: 80 records · 1996–2026
- The source has not said who or what was studied: 572 records · 1991–2026
- No matching published catalogue records are linked above. Human-review status must be checked on the evidence itself.
Published in this map
Catalogue records matching this subject. Publication here does not establish human review, measured results or effectiveness. Open a record to inspect its sources and evidence.
No published catalogue records match this subject yet.
This is a result within this map, not a claim that no research exists. The source records below can help you continue searching.
Found in the scientific sources, not yet checked
Titles and identifiers as the sources publish them. Nobody here has read these papers, and nothing on this shelf is a result, a recommendation or evidence that anything works. Each line opens the original.
3706 records
This grouping is the source's own cataloguing, not a reading of the paper. It says where a record was filed, not what it found.
Indexed as work in animals
- Implantable porous gelatin microspheres sustained release of bFGF and improved its neuroprotective effect on rats after spinal cord injury. — PubMed · 2017 · Journal Article
- Neural Stem Cell-Conditioned Medium Suppresses Inflammation and Promotes Spinal Cord Injury Recovery. — PubMed · 2017 · Journal Article
- Neuroprotective effects of lycopene in spinal cord injury in rats via antioxidative and anti-apoptotic pathway. — PubMed · 2017 · Journal Article
- Pharmacological inhibition of spinal cord injury-stimulated ribosomal biogenesis does not affect locomotor outcome. — PubMed · 2017 · Journal Article
- A Thermosensitive Heparin-Poloxamer Hydrogel Bridges aFGF to Treat Spinal Cord Injury. — PubMed · 2017 · Journal Article
- Diadenosine tetraphosphate (Ap(4)A) inhibits ATP-induced excitotoxicity: a neuroprotective strategy for traumatic spinal cord injury treatment. — PubMed · 2017 · Journal Article
- Longitudinal enlargement of the lesion after spinal cord injury in the rat: a consequence of malignant edema? — PubMed · 2017 · Journal Article
- Melatonin prevents blood vessel loss and neurological impairment induced by spinal cord injury in rats. — PubMed · 2017 · Journal Article
- Simvastatin protects ischemic spinal cord injury from cell death and cytotoxicity through decreasing oxidative stress: in vitro primary cultured rat spinal cord model under oxygen and glucose deprivation-reoxygenation conditions. — PubMed · 2017 · Journal Article
- Salvianolic acid A ameliorates the integrity of blood-spinal cord barrier via miR-101/Cul3/Nrf2/HO-1 signaling pathway. — PubMed · 2017 · Journal Article
- The protective effect of curcumin in Olfactory Ensheathing Cells exposed to hypoxia. — PubMed · 2017 · Journal Article
- AC105 Increases Extracellular Magnesium Delivery and Reduces Excitotoxic Glutamate Exposure within Injured Spinal Cords in Rats. — PubMed · 2017 · Journal Article
- Estrogen-like neuroprotection of isopsoralen against spinal cord injury through estrogen receptor ERα. — PubMed · 2017 · Journal Article
- Methane ameliorates spinal cord ischemia-reperfusion injury in rats: Antioxidant, anti-inflammatory and anti-apoptotic activity mediated by Nrf2 activation. — PubMed · 2017 · Journal Article
- Peptide-Tethered Hydrogel Scaffold Promotes Recovery from Spinal Cord Transection via Synergism with Mesenchymal Stem Cells. — PubMed · 2017 · Journal Article
- Identifying the Long-Term Role of Inducible Nitric Oxide Synthase after Contusive Spinal Cord Injury Using a Transgenic Mouse Model. — PubMed · 2017 · Journal Article
- Protease-Activated Receptor-1 Supports Locomotor Recovery by Biased Agonist Activated Protein C after Contusive Spinal Cord Injury. — PubMed · 2017 · Journal Article
- Effects of STAT3 inhibitors on neural functional recovery after spinal cord injury in rats. — PubMed · 2017 · Journal Article
- Synchrotron radiation micro-CT as a novel tool to evaluate the effect of agomir-210 in a rat spinal cord injury model. — PubMed · 2017 · Journal Article
- Combined and individual use of pancaspase inhibitor Q-VD-OPh and NMDA receptor antagonist riluzole in experimental spinal cord injury. — PubMed · 2017 · Journal Article
- Combined polymer-curcumin conjugate and ependymal progenitor/stem cell treatment enhances spinal cord injury functional recovery. — PubMed · 2017 · Journal Article
- Effect of Asiatic Acid on the Treatment of Spinal Cord Injury: An Experimental Study in Rats. — PubMed · 2017 · Journal Article
- Effect of Shikonin on Spinal Cord Injury in Rats Via Regulation of HMGB1/TLR4/NF-kB Signaling Pathway. — PubMed · 2017 · Journal Article
- Effects of Atorvastatin on Experimental Spinal Cord Ischemia-Reperfusion Injury in Rabbits. — PubMed · 2017 · Journal Article
- Extremely low frequency magnetic field protects injured spinal cord from the microglia- and iron-induced tissue damage. — PubMed · 2017 · Journal Article
- Intravenous Administration of Functionalized Magnetic Iron Oxide Nanoparticles Does Not Induce CNS Injury in the Rat: Influence of Spinal Cord Trauma and Cerebrolysin Treatment. — PubMed · 2017 · Journal Article
- Local delivery of minocycline from metal ion-assisted self-assembled complexes promotes neuroprotection and functional recovery after spinal cord injury. — PubMed · 2017 · Journal Article
- Multiple beneficial effects of melanocortin MC(4) receptor agonists in experimental neurodegenerative disorders: Therapeutic perspectives. — PubMed · 2017 · Journal Article
- The Neuroprotective Effects of Muscle-Derived Stem Cells via Brain-Derived Neurotrophic Factor in Spinal Cord Injury Model. — PubMed · 2017 · Journal Article
- Valproic acid preserves motoneurons following contusion in organotypic spinal cord slice culture. — PubMed · 2017 · Journal Article
- Cell-Based Delivery of Interleukin-13 Directs Alternative Activation of Macrophages Resulting in Improved Functional Outcome after Spinal Cord Injury. — PubMed · 2016 · Journal Article
- Chondroitinase administration and pcDNA3.1-BDNF-BMSC transplantation promote motor functional recovery associated with NGF expression in spinal cord-transected rat. — PubMed · 2016 · Journal Article
- Combined application of Rho-ROCKII and GSK-3β inhibitors exerts an improved protective effect on axonal regeneration in rats with spinal cord injury. — PubMed · 2016 · Journal Article
- Effects of melatonin on severe crush spinal cord injury-induced reactive astrocyte and scar formation. — PubMed · 2016 · Journal Article
- Granulocyte Colony-Stimulating Factor Improves Motor Function in Rats Developing Compression Myelopathy. — PubMed · 2016 · Journal Article
- IL-4 drives microglia and macrophages toward a phenotype conducive for tissue repair and functional recovery after spinal cord injury. — PubMed · 2016 · Journal Article
- New Xymedon Analogues for Stimulation of Posttraumatic Regeneration of the Spinal Cord in Rats. — PubMed · 2016 · Journal Article
- Gut dysbiosis impairs recovery after spinal cord injury. — PubMed · 2016 · Journal Article
- Age increases reactive oxygen species production in macrophages and potentiates oxidative damage after spinal cord injury. — PubMed · 2016 · Journal Article
- Therapeutic efficacy of tadalafil and eriythropoietin in experimental spinal cord injury. — PubMed · 2016 · Journal Article
- Probenecid and N-Acetylcysteine Prevent Loss of Intracellular Glutathione and Inhibit Neuronal Death after Mechanical Stretch Injury In Vitro. — PubMed · 2016 · Journal Article
- Aescin reduces oxidative stress and provides neuroprotection in experimental traumatic spinal cord injury. — PubMed · 2016 · Journal Article
- Allicin protects traumatic spinal cord injury through regulating the HSP70/Akt/iNOS pathway in mice. — PubMed · 2016 · Journal Article
- A novel translocator protein 18 kDa ligand, ZBD-2, exerts neuroprotective effects against acute spinal cord injury. — PubMed · 2016 · Journal Article
- Neuroprotective effect of propofol against excitotoxic injury to locomotor networks of the rat spinal cord in vitro. — PubMed · 2016 · Journal Article
- Quantitative analysis of hindlimbs locomotion kinematics in spinalized rats treated with Tamoxifen plus treadmill exercise. — PubMed · 2016 · Journal Article
- Tetramethylpyrazine enhances functional recovery after contusion spinal cord injury by modulation of MicroRNA-21, FasL, PDCD4 and PTEN expression. — PubMed · 2016 · Journal Article
- Tamoxifen Administration Immediately or 24 Hours after Spinal Cord Injury Improves Locomotor Recovery and Reduces Secondary Damage in Female Rats. — PubMed · 2016 · Journal Article
- Xenon-delayed postconditioning attenuates spinal cord ischemia/reperfusion injury through activation AKT and ERK signaling pathways in rats. — PubMed · 2016 · Journal Article
- A Coral-Derived Compound Improves Functional Recovery after Spinal Cord Injury through Its Antiapoptotic and Anti-Inflammatory Effects. — PubMed · 2016 · Journal Article
- Metformin preconditioning provide neuroprotection through enhancement of autophagy and suppression of inflammation and apoptosis after spinal cord injury. — PubMed · 2016 · Journal Article
- Gelatin Nanostructured Lipid Carriers Incorporating Nerve Growth Factor Inhibit Endoplasmic Reticulum Stress-Induced Apoptosis and Improve Recovery in Spinal Cord Injury. — PubMed · 2016 · Journal Article
- Transplantation of Mesenchymal Stem Cells for Acute Spinal Cord Injury in Rats: Comparative Study between Intralesional Injection and Scaffold Based Transplantation. — PubMed · 2016 · Comparative Study
- G-1 exerts neuroprotective effects through G protein-coupled estrogen receptor 1 following spinal cord injury in mice. — PubMed · 2016 · Journal Article
- GAPDH/Siah1 cascade is involved in traumatic spinal cord injury and could be attenuated by sivelestat sodium. — PubMed · 2016 · Journal Article
- SUR1-Associated Mechanisms Are Not Involved in Ischemic Optic Neuropathy 1 Day Post-Injury. — PubMed · 2016 · Journal Article
- Glutamate Increases In Vitro Survival and Proliferation and Attenuates Oxidative Stress-Induced Cell Death in Adult Spinal Cord-Derived Neural Stem/Progenitor Cells via Non-NMDA Ionotropic Glutamate Receptors. — PubMed · 2016 · Journal Article
- Micro-CT as a Tool to Investigate the Efficacy of Tetramethylpyrazine in a Rat Spinal Cord Injury Model. — PubMed · 2016 · Journal Article
- miR-155 Deletion in Mice Overcomes Neuron-Intrinsic and Neuron-Extrinsic Barriers to Spinal Cord Repair. — PubMed · 2016 · Journal Article
- [NEUROPROTECTIVE EFFECTS OF MANGIFERIN ON ACUTE SPINAL CORD INJURY IN RATS AND ITS MECHANISM]. — PubMed · 2016 · Journal Article
Where this was looked for, and when
The latest collection walk and the accumulated shelf have different scopes. A zero applies only to that source query and its date window; older records may remain on the shelf. It does not mean no research exists.
| ClinicalTrials.gov | latest collection walk returned no records | asked on 2026-10-05 Collection window: 2026-09-16 – 2026-10-05 | matched in this collection walk 0 · accumulated records across collection walks 6 · still to fetch in this walk 0 | aim: every record matching this question |
|---|---|---|---|---|
| Crossref | asked, and it answered | asked on 2026-09-16 Collection window: all dates before the end date – 2026-09-16 | matched in this collection walk 1230843 · accumulated records across collection walks 50 | aim: a sample of the most relevant records. This source ranks a bag of words, so its own total is the size of the corpus that shares some of them, never a set still owed. |
| PubMed | asked, and it answered | asked on 2026-09-17 Collection window: all dates before the end date – 2026-09-17 | matched in this collection walk 3744 · accumulated records across collection walks 3744 · still to fetch in this walk 0 | aim: every record matching this question |
The question asked
- ClinicalTrials.gov
("neuroprotection" OR "secondary injury") - Crossref
spinal cord injury neuroprotection secondary injury - PubMed
("Spinal Cord Injuries"[MeSH Terms] OR "spinal cord injury"[Title/Abstract] OR "spinal cord injuries"[Title/Abstract] OR "spinal cord trauma"[Title/Abstract]) AND ("Neuroprotection"[MeSH Terms] OR "Neuroprotective Agents"[MeSH Terms] OR "neuroprotection"[Title/Abstract] OR "secondary injury"[Title/Abstract])