A subject this map covers
Neuroprotection
What belongs here
Attempts to stop the second, delayed wave of damage in the first hours and days.
What does not belong here, however close it looks
Restoring function lost months earlier is repair, not neuroprotection.
What has been looked at
Counted from what the sources catalogue, not from reading the work. It says how much exists and over what span of years — never what any of it found.
- Registered or indexed as work in people: 1169 records · 1978–2027
- Indexed as work in animals: 1885 records · 1977–2026
- Indexed as laboratory work: 80 records · 1996–2026
- The source has not said who or what was studied: 572 records · 1991–2026
- No matching published catalogue records are linked above. Human-review status must be checked on the evidence itself.
Published in this map
Catalogue records matching this subject. Publication here does not establish human review, measured results or effectiveness. Open a record to inspect its sources and evidence.
No published catalogue records match this subject yet.
This is a result within this map, not a claim that no research exists. The source records below can help you continue searching.
Found in the scientific sources, not yet checked
Titles and identifiers as the sources publish them. Nobody here has read these papers, and nothing on this shelf is a result, a recommendation or evidence that anything works. Each line opens the original.
3706 records
This grouping is the source's own cataloguing, not a reading of the paper. It says where a record was filed, not what it found.
Indexed as work in animals
- Probucol inhibits neural cell apoptosis via inhibition of mTOR signaling pathway after spinal cord injury. — PubMed · 2016 · Journal Article
- Combining neuroprotective agents: effect of riluzole and magnesium in a rat model of thoracic spinal cord injury. — PubMed · 2016 · Journal Article
- In vivo PET imaging of the neuroinflammatory response in rat spinal cord injury using the TSPO tracer [(18)F]GE-180 and effect of docosahexaenoic acid. — PubMed · 2016 · Journal Article
- Neuroprotective Effect of Ginsenoside Rd in Spinal Cord Injury Rats. — PubMed · 2016 · Journal Article
- The Association of Palmitoylethanolamide with Luteolin Decreases Autophagy in Spinal Cord Injury. — PubMed · 2016 · Journal Article The source marks this record as retracted.
- The Ganglioside GM-1 Inhibits Bupivacaine-Induced Neurotoxicity in Mouse Neuroblastoma Neuro2a Cells. — PubMed · 2016 · Journal Article
- Toll like receptor 9 antagonism modulates spinal cord neuronal function and survival: Direct versus astrocyte-mediated mechanisms. — PubMed · 2016 · Journal Article
- Lentivirus-mediated PGC-1α overexpression protects against traumatic spinal cord injury in rats. — PubMed · 2016 · Journal Article
- Neuroprotective effect of asiatic acid against spinal cord injury in rats. — PubMed · 2016 · Journal Article
- Activation and Regulation of NLRP3 Inflammasome by Intrathecal Application of SDF-1a in a Spinal Cord Injury Model. — PubMed · 2016 · Journal Article
- Effects of calcitriol on experimental spinal cord injury in rats. — PubMed · 2016 · Journal Article
- Effects of ganglioside G(M1) and erythropoietin on spinal cord lesions in rats: functional and histological evaluations. — PubMed · 2016 · Journal Article
- Exogenous Neuritin Promotes Nerve Regeneration After Acute Spinal Cord Injury in Rats. — PubMed · 2016 · Journal Article
- Hyaluronic acid scaffold has a neuroprotective effect in hemisection spinal cord injury. — PubMed · 2016 · Journal Article
- Microenvironmental regulation of oligodendrocyte replacement and remyelination in spinal cord injury. — PubMed · 2016 · Journal Article
- Mitigation of sensory and motor deficits by acrolein scavenger phenelzine in a rat model of spinal cord contusive injury. — PubMed · 2016 · Journal Article
- Simvastatin inhibits neural cell apoptosis and promotes locomotor recovery via activation of Wnt/β-catenin signaling pathway after spinal cord injury. — PubMed · 2016 · Journal Article
- C-C motif chemokine ligand 20 regulates neuroinflammation following spinal cord injury via Th17 cell recruitment. — PubMed · 2016 · Journal Article
- Alleviation of spinal cord injury by Ginkgolide B via the inhibition of STAT1 expression. — PubMed · 2016 · Journal Article
- Bone Marrow Stromal Cell Intraspinal Transplants Fail to Improve Motor Outcomes in a Severe Model of Spinal Cord Injury. — PubMed · 2016 · Journal Article
- Rutin attenuates neuroinflammation in spinal cord injury rats. — PubMed · 2016 · Journal Article
- Amiloride Analogs as ASIC1a Inhibitors. — PubMed · 2016 · Journal Article
- An In Situ Gelling Drug Delivery System for Improved Recovery after Spinal Cord Injury. — PubMed · 2016 · Journal Article
- Effectiveness of minocycline and FK506 alone and in combination on enhanced behavioral and biochemical recovery from spinal cord injury in rats. — PubMed · 2016 · Journal Article
- Inhibition of p21-Activated Kinase 1 by IPA-3 Promotes Locomotor Recovery After Spinal Cord Injury in Mice. — PubMed · 2016 · Journal Article
- Neuroprotective effects of thymoquinone against spinal cord ischemia-reperfusion injury by attenuation of inflammation, oxidative stress, and apoptosis. — PubMed · 2016 · Journal Article
- Rescuing macrophage normal function in spinal cord injury with embryonic stem cell conditioned media. — PubMed · 2016 · Journal Article
- Administration of low dose estrogen attenuates persistent inflammation, promotes angiogenesis, and improves locomotor function following chronic spinal cord injury in rats. — PubMed · 2016 · Journal Article
- Rosiglitazone attenuates inflammation and CA3 neuronal loss following traumatic brain injury in rats. — PubMed · 2016 · Journal Article
- [EFFECT OF TIME-RELATED ADMINISTRATION OF METHOTREXATE ON SPINAL CORD INJURY-INDUCED NEURAL CELL APOPTOSIS IN RATS]. — PubMed · 2016 · Evaluation Study
- EGb761 improves histological and functional recovery in rats with acute spinal cord contusion injury. — PubMed · 2016 · Journal Article
- Inhibition of Autophagy by Estradiol Promotes Locomotor Recovery after Spinal Cord Injury in Rats. — PubMed · 2016 · Journal Article
- Effect of FGF-2 and sciatic nerve grafting on ChAT expression in dorsal root ganglia neurons of spinal cord transected rats. — PubMed · 2016 · Journal Article
- Administration of low dose estrogen attenuates gliosis and protects neurons in acute spinal cord injury in rats. — PubMed · 2016 · Journal Article
- Caffeine treatment aggravates secondary degeneration after spinal cord injury. — PubMed · 2016 · Journal Article
- Dopamine D1 Receptor Agonist A-68930 Inhibits NLRP3 Inflammasome Activation, Controls Inflammation, and Alleviates Histopathology in a Rat Model of Spinal Cord Injury. — PubMed · 2016 · Journal Article
- Neuroprotective effect of hydrogen sulfide on acute cauda equina injury in rats. — PubMed · 2016 · Journal Article
- Heme oxygenase-1 promotes neuron survival through down-regulation of neuronal NLRP1 expression after spinal cord injury. — PubMed · 2016 · Journal Article
- A study of methylprednisolone neuroprotection against acute injury to the rat spinal cord in vitro. — PubMed · 2016 · Journal Article
- Tetramethylpyrazine improves the recovery of spinal cord injury via Akt/Nrf2/HO-1 pathway. — PubMed · 2016 · Journal Article
- Beneficial effects of IL-37 after spinal cord injury in mice. — PubMed · 2016 · Journal Article
- Intrathecal Acetyl-L-Carnitine Protects Tissue and Improves Function after a Mild Contusive Spinal Cord Injury in Rats. — PubMed · 2016 · Journal Article
- Proof-of Concept that an Acute Trophic Factors Intervention After Spinal Cord Injury Provides an Adequate Niche for Neuroprotection, Recruitment of Nestin-Expressing Progenitors and Regeneration. — PubMed · 2016 · Journal Article
- Riluzole promotes motor and respiratory recovery associated with enhanced neuronal survival and function following high cervical spinal hemisection. — PubMed · 2016 · Journal Article
- Stabilization of HIF-1α by FG-4592 promotes functional recovery and neural protection in experimental spinal cord injury. — PubMed · 2016 · Journal Article
- Temporal and Regional Expression of Glucose-Dependent Insulinotropic Peptide and Its Receptor in Spinal Cord Injured Rats. — PubMed · 2016 · Journal Article
- Dietary Supplementation with Organoselenium Accelerates Recovery of Bladder Expression, but Does Not Improve Locomotor Function, following Spinal Cord Injury. — PubMed · 2016 · Journal Article
- Cyclic AMP is a key regulator of M1 to M2a phenotypic conversion of microglia in the presence of Th2 cytokines. — PubMed · 2016 · Journal Article
- A Placebo-Controlled, Prospective, Randomized Clinical Trial of Polyethylene Glycol and Methylprednisolone Sodium Succinate in Dogs with Intervertebral Disk Herniation. — PubMed · 2016 · Journal Article
- Comparative Biochemical and Motor Function Analysis of Alpha Lipoic Acid and N-Acetyl Cysteine Treatment on Rats with Experimental Spinal Cord Injury. — PubMed · 2016 · Comparative Study
- Comparison of Etanercept, Etomidate and Erythropoietin and Their Combinations in Experimentally-Induced Spinal Cord Injury. — PubMed · 2016 · Comparative Study
- Effects of Electroacupuncture at Governor Vessel Acupoints on Neurotrophin-3 in Rats with Experimental Spinal Cord Injury. — PubMed · 2016 · Journal Article
- Gastrodin ameliorates spinal cord injury via antioxidant and anti-inflammatory effects. — PubMed · 2016 · Journal Article
- Histopathological Evaluation of the Effects of CAPE in Experimental Spinal Cord Injury. — PubMed · 2016 · Comparative Study
- MP Resulting in Autophagic Cell Death of Microglia through Zinc Changes against Spinal Cord Injury. — PubMed · 2016 · Journal Article
- Neuroprotective effects of the Buyang Huanwu decoction on functional recovery in rats following spinal cord injury. — PubMed · 2016 · Journal Article
- The Biochemical, Histopathological and Clinical Comparison of the Neuroprotective Effects of Subcutaneous Adalimumab and Intravenous Methylprednisolone in an Experimental Compressive Spinal Cord Trauma Model. — PubMed · 2016 · Comparative Study
- The Neuroprotective Effect of Puerarin in Acute Spinal Cord Injury Rats. — PubMed · 2016 · Journal Article
- Neuroprotective effect of allicin in a rat model of acute spinal cord injury. — PubMed · 2015 · Journal Article
- CISD2 serves a novel role as a suppressor of nitric oxide signalling and curcumin increases CISD2 expression in spinal cord injuries. — PubMed · 2015 · Journal Article
Where this was looked for, and when
The latest collection walk and the accumulated shelf have different scopes. A zero applies only to that source query and its date window; older records may remain on the shelf. It does not mean no research exists.
| ClinicalTrials.gov | latest collection walk returned no records | asked on 2026-10-05 Collection window: 2026-09-16 – 2026-10-05 | matched in this collection walk 0 · accumulated records across collection walks 6 · still to fetch in this walk 0 | aim: every record matching this question |
|---|---|---|---|---|
| Crossref | asked, and it answered | asked on 2026-09-16 Collection window: all dates before the end date – 2026-09-16 | matched in this collection walk 1230843 · accumulated records across collection walks 50 | aim: a sample of the most relevant records. This source ranks a bag of words, so its own total is the size of the corpus that shares some of them, never a set still owed. |
| PubMed | asked, and it answered | asked on 2026-09-17 Collection window: all dates before the end date – 2026-09-17 | matched in this collection walk 3744 · accumulated records across collection walks 3744 · still to fetch in this walk 0 | aim: every record matching this question |
The question asked
- ClinicalTrials.gov
("neuroprotection" OR "secondary injury") - Crossref
spinal cord injury neuroprotection secondary injury - PubMed
("Spinal Cord Injuries"[MeSH Terms] OR "spinal cord injury"[Title/Abstract] OR "spinal cord injuries"[Title/Abstract] OR "spinal cord trauma"[Title/Abstract]) AND ("Neuroprotection"[MeSH Terms] OR "Neuroprotective Agents"[MeSH Terms] OR "neuroprotection"[Title/Abstract] OR "secondary injury"[Title/Abstract])