A subject this map covers
Neuroprotection
What belongs here
Attempts to stop the second, delayed wave of damage in the first hours and days.
What does not belong here, however close it looks
Restoring function lost months earlier is repair, not neuroprotection.
What has been looked at
Counted from what the sources catalogue, not from reading the work. It says how much exists and over what span of years — never what any of it found.
- Registered or indexed as work in people: 1169 records · 1978–2027
- Indexed as work in animals: 1885 records · 1977–2026
- Indexed as laboratory work: 80 records · 1996–2026
- The source has not said who or what was studied: 572 records · 1991–2026
- No matching published catalogue records are linked above. Human-review status must be checked on the evidence itself.
Published in this map
Catalogue records matching this subject. Publication here does not establish human review, measured results or effectiveness. Open a record to inspect its sources and evidence.
No published catalogue records match this subject yet.
This is a result within this map, not a claim that no research exists. The source records below can help you continue searching.
Found in the scientific sources, not yet checked
Titles and identifiers as the sources publish them. Nobody here has read these papers, and nothing on this shelf is a result, a recommendation or evidence that anything works. Each line opens the original.
3706 records
This grouping is the source's own cataloguing, not a reading of the paper. It says where a record was filed, not what it found.
Indexed as work in animals
- Hyperbaric Oxygen Treatment Protects Against Spinal Cord Injury by Inhibiting Endoplasmic Reticulum Stress in Rats. — PubMed · 2015 · Journal Article
- Neuroprotective effects and impact on caspase-12 expression of tauroursodeoxycholic acid after acute spinal cord injury in rats. — PubMed · 2015 · Journal Article
- Azithromycin drives alternative macrophage activation and improves recovery and tissue sparing in contusion spinal cord injury. — PubMed · 2015 · Journal Article
- Protective effects of Ephedra sinica extract on blood-brain barrier integrity and neurological function correlate with complement C3 reduction after subarachnoid hemorrhage in rats. — PubMed · 2015 · Journal Article
- Acute Phase Proteins in Cerebrospinal Fluid from Dogs with Naturally-Occurring Spinal Cord Injury. — PubMed · 2015 · Journal Article
- A Direct Comparison of Three Clinically Relevant Treatments in a Rat Model of Cervical Spinal Cord Injury. — PubMed · 2015 · Comparative Study
- Age decreases macrophage IL-10 expression: Implications for functional recovery and tissue repair in spinal cord injury. — PubMed · 2015 · Journal Article
- Mangiferin attenuates contusive spinal cord injury in rats through the regulation of oxidative stress, inflammation and the Bcl‑2 and Bax pathway. — PubMed · 2015 · Journal Article
- Necroptosis, a novel type of programmed cell death, contributes to early neural cells damage after spinal cord injury in adult mice. — PubMed · 2015 · Journal Article
- Neuroprotective effects of Ganoderma lucidum polysaccharides against traumatic spinal cord injury in rats. — PubMed · 2015 · Journal Article
- Protective role of selenium-enriched supplement on spinal cord injury through the up-regulation of CNTF and CNTF-Ralpha. — PubMed · 2015 · Journal Article
- A nutrient combination designed to enhance synapse formation and function improves outcome in experimental spinal cord injury. — PubMed · 2015 · Journal Article
- Carvacrol protects against spinal cord injury in rats via suppressing oxidative stress and the endothelial nitric oxide synthase pathway. — PubMed · 2015 · Journal Article
- Effects of estrogen on functional and neurological recovery after spinal cord injury: An experimental study with rats. — PubMed · 2015 · Journal Article
- Ligustilide treatment promotes functional recovery in a rat model of spinal cord injury via preventing ROS production. — PubMed · 2015 · Journal Article
- Nanoparticles Exacerbate Both Ubiquitin and Heat Shock Protein Expressions in Spinal Cord Injury: Neuroprotective Effects of the Proteasome Inhibitor Carfilzomib and the Antioxidant Compound H-290/51. — PubMed · 2015 · Journal Article
- Nanowired Delivery of Growth Hormone Attenuates Pathophysiology of Spinal Cord Injury and Enhances Insulin-Like Growth Factor-1 Concentration in the Plasma and the Spinal Cord. — PubMed · 2015 · Journal Article The source marks this record as retracted.
- Protective Effect of Pyrroloquinoline Quinone (PQQ) in Rat Model of Intracerebral Hemorrhage. — PubMed · 2015 · Journal Article
- The combination of insulin-like growth factor 1 and erythropoietin protects against ischemic spinal cord injury in rabbits. — PubMed · 2015 · Journal Article
- A Single Bolus of Docosahexaenoic Acid Promotes Neuroplastic Changes in the Innervation of Spinal Cord Interneurons and Motor Neurons and Improves Functional Recovery after Spinal Cord Injury. — PubMed · 2015 · Journal Article
- Serotonin 5-HT7 receptor agonist, LP-211, exacerbates Na(+), K(+)-ATPase/Mg(2+)-ATPase imbalances in spinal cord-injured male rats. — PubMed · 2015 · Journal Article The source marks this record as retracted.
- Contusive spinal cord injury up regulates mu-opioid receptor (mor) gene expression in the brain and down regulates its expression in the spinal cord: possible implications in spinal cord injury research. — PubMed · 2015 · Journal Article
- Neuroprotective Effects of Direct Intrathecal Administration of Granulocyte Colony-Stimulating Factor in Rats with Spinal Cord Injury. — PubMed · 2015 · Journal Article
- Prolonged Local Hypothermia Has No Long-Term Adverse Effect on the Spinal Cord. — PubMed · 2015 · Journal Article
- Acute administration of ucf-101 ameliorates the locomotor impairments induced by a traumatic spinal cord injury. — PubMed · 2015 · Journal Article
- Comparison of the Effects of Methotrexate and Methylprednisolone in Spinal Cord Injury in Rats. — PubMed · 2015 · Comparative Study
- [Effect of Herba Lycopodii Alcohol Extracted Granule Combined Methylprednisolone on Expression Levels of BDNF and NMDA and Behavior of Traumatic Spinal Cord Injury Rats]. — PubMed · 2015 · Journal Article
- Endoplasmic Reticulum Protein 29 Protects Axotomized Neurons from Apoptosis and Promotes Neuronal Regeneration Associated with Erk Signal. — PubMed · 2015 · Journal Article
- G-protein-coupled receptor 30-mediated antiapoptotic effect of estrogen on spinal motor neurons following injury and its underlying mechanisms. — PubMed · 2015 · Journal Article
- Injury potentials of spinal cord in ex vivo compression injury model. — PubMed · 2015 · Journal Article
- Local Injection of Lenti-BDNF at the Lesion Site Promotes M2 Macrophage Polarization and Inhibits Inflammatory Response After Spinal Cord Injury in Mice. — PubMed · 2015 · Journal Article
- Neuroprotective effect of methylprednisolone combined with placenta-derived mesenchymal stem cell in rabbit model of spinal cord injury. — PubMed · 2015 · Journal Article
- Neuroprotective effects of nitidine against traumatic CNS injury via inhibiting microglia activation. — PubMed · 2015 · Journal Article
- Protective effect and mechanism of probucol in the treatment of spinal cord injury. — PubMed · 2015 · Journal Article
- Photothrombosis-induced Focal Ischemia as a Model of Spinal Cord Injury in Mice. — PubMed · 2015 · Journal Article
- Activation of Lysophosphatidic Acid Receptor Type 1 Contributes to Pathophysiology of Spinal Cord Injury. — PubMed · 2015 · Journal Article
- Toll-Like Receptors and Dectin-1, a C-Type Lectin Receptor, Trigger Divergent Functions in CNS Macrophages. — PubMed · 2015 · Journal Article
- Chemically functionalized single-walled carbon nanotubes enhance the glutamate uptake characteristics of mouse cortical astrocytes. — PubMed · 2015 · Journal Article
- Effect of estrogen on recovering the injured nervous system. — PubMed · 2015 · Journal Article
- Functional recovery in spinal cord injured rats using polypyrrole/iodine implants and treadmill training. — PubMed · 2015 · Journal Article
- Monitoring of Short-Term Erythropoietin Therapy in Rats with Acute Spinal Cord Injury Using Manganese-Enhanced Magnetic Resonance Imaging. — PubMed · 2015 · Journal Article
- The Neuroprotective Effect of Tetramethylpyrazine Against Contusive Spinal Cord Injury by Activating PGC-1α in Rats. — PubMed · 2015 · Journal Article
- Effects of Therapeutic Hypothermia on Apoptosis and Autophagy After Spinal Cord Injury in Rats. — PubMed · 2015 · Comparative Study
- Protective effects of LM22A-4 on injured spinal cord nerves. — PubMed · 2015 · Journal Article
- 17β-estradiol inhibits MMP-9 and SUR1/TrpM4 expression and activation and thereby attenuates BSCB disruption/hemorrhage after spinal cord injury in male rats. — PubMed · 2015 · Journal Article
- Histamine promotes locomotion recovery after spinal cord hemisection via inhibiting astrocytic scar formation. — PubMed · 2015 · Journal Article
- Neuroprotective effects of exendin-4 in rat model of spinal cord injury via inhibiting mitochondrial apoptotic pathway. — PubMed · 2015 · Journal Article
- Progesterone treatment in two rat models of ocular ischemia. — PubMed · 2015 · Journal Article
- Role of adaptor protein MyD88 in TLR-mediated preconditioning and neuroprotection after acute excitotoxicity. — PubMed · 2015 · Journal Article
- Neuroprotective effect of ketamine on acute spinal cord injury in rats. — PubMed · 2015 · Journal Article
- Promoting endothelial function by S-nitrosoglutathione through the HIF-1α/VEGF pathway stimulates neurorepair and functional recovery following experimental stroke in rats. — PubMed · 2015 · Journal Article
- Early applied electric field stimulation attenuates secondary apoptotic responses and exerts neuroprotective effects in acute spinal cord injury of rats. — PubMed · 2015 · Journal Article
- Expedited access to vinaxanthone and chemically edited derivatives possessing neuronal regenerative effects through ynone coupling reactions. — PubMed · 2015 · Journal Article
- Effects of tadalafil-Type-V phosphodiesterase enzyme inhibitor-On rats with spinal trauma. — PubMed · 2015 · Journal Article
- Potential neuroprotective effect of Anakinra in spinal cord injury in an in vivo experimental animal model. — PubMed · 2015 · Journal Article
- Necrostatin-1 mitigates mitochondrial dysfunction post-spinal cord injury. — PubMed · 2015 · Journal Article
- Honokiol downregulates Kruppel-like factor 4 expression, attenuates inflammation, and reduces histopathology after spinal cord injury in rats. — PubMed · 2015 · Journal Article
- Adoptive transfer of M2 macrophages promotes locomotor recovery in adult rats after spinal cord injury. — PubMed · 2015 · Journal Article
- Brain protection conferred by long-term administration of 2-(2-benzofuranyl)-2-imidazoline against experimental autoimmune encephalomyelitis. — PubMed · 2015 · Journal Article
- Down-sizing of neuronal network activity and density of presynaptic terminals by pathological acidosis are efficiently prevented by Diminazene Aceturate. — PubMed · 2015 · Journal Article
Where this was looked for, and when
The latest collection walk and the accumulated shelf have different scopes. A zero applies only to that source query and its date window; older records may remain on the shelf. It does not mean no research exists.
| ClinicalTrials.gov | latest collection walk returned no records | asked on 2026-10-05 Collection window: 2026-09-16 – 2026-10-05 | matched in this collection walk 0 · accumulated records across collection walks 6 · still to fetch in this walk 0 | aim: every record matching this question |
|---|---|---|---|---|
| Crossref | asked, and it answered | asked on 2026-09-16 Collection window: all dates before the end date – 2026-09-16 | matched in this collection walk 1230843 · accumulated records across collection walks 50 | aim: a sample of the most relevant records. This source ranks a bag of words, so its own total is the size of the corpus that shares some of them, never a set still owed. |
| PubMed | asked, and it answered | asked on 2026-09-17 Collection window: all dates before the end date – 2026-09-17 | matched in this collection walk 3744 · accumulated records across collection walks 3744 · still to fetch in this walk 0 | aim: every record matching this question |
The question asked
- ClinicalTrials.gov
("neuroprotection" OR "secondary injury") - Crossref
spinal cord injury neuroprotection secondary injury - PubMed
("Spinal Cord Injuries"[MeSH Terms] OR "spinal cord injury"[Title/Abstract] OR "spinal cord injuries"[Title/Abstract] OR "spinal cord trauma"[Title/Abstract]) AND ("Neuroprotection"[MeSH Terms] OR "Neuroprotective Agents"[MeSH Terms] OR "neuroprotection"[Title/Abstract] OR "secondary injury"[Title/Abstract])