A subject this map covers
Neuroprotection
What belongs here
Attempts to stop the second, delayed wave of damage in the first hours and days.
What does not belong here, however close it looks
Restoring function lost months earlier is repair, not neuroprotection.
What has been looked at
Counted from what the sources catalogue, not from reading the work. It says how much exists and over what span of years — never what any of it found.
- Registered or indexed as work in people: 1169 records · 1978–2027
- Indexed as work in animals: 1885 records · 1977–2026
- Indexed as laboratory work: 80 records · 1996–2026
- The source has not said who or what was studied: 572 records · 1991–2026
- No matching published catalogue records are linked above. Human-review status must be checked on the evidence itself.
Published in this map
Catalogue records matching this subject. Publication here does not establish human review, measured results or effectiveness. Open a record to inspect its sources and evidence.
No published catalogue records match this subject yet.
This is a result within this map, not a claim that no research exists. The source records below can help you continue searching.
Found in the scientific sources, not yet checked
Titles and identifiers as the sources publish them. Nobody here has read these papers, and nothing on this shelf is a result, a recommendation or evidence that anything works. Each line opens the original.
3706 records
This grouping is the source's own cataloguing, not a reading of the paper. It says where a record was filed, not what it found.
Indexed as work in animals
- Tempol reduces injury area in rat model of spinal cord contusion injury through suppression of iNOS and COX-2 expression. — PubMed · 2013 · Journal Article
- Anti-edema effect of epigallocatechin gallate on spinal cord injury in rats. — PubMed · 2013 · Journal Article
- Effect of sodium hydrosulphide after acute compression injury of spinal cord. — PubMed · 2013 · Journal Article
- Temporal changes in monocyte and macrophage subsets and microglial macrophages following spinal cord injury in the Lys-Egfp-ki mouse model. — PubMed · 2013 · Journal Article
- Hormonal and histological changes in the ovaries with high-doses of methylprednisolone administration for acute spinal cord injury: an experimental study. — PubMed · 2013 · Journal Article
- Host reaction to poly(2-hydroxyethyl methacrylate) scaffolds in a small spinal cord injury model. — PubMed · 2013 · Journal Article
- Protective effects of Batroxobin on spinal cord injury in rats. — PubMed · 2013 · Journal Article
- Valproic acid reduces autophagy and promotes functional recovery after spinal cord injury in rats. — PubMed · 2013 · Journal Article
- Effects of combined and individual use of N-methyl-D aspartate receptor antagonist magnesium sulphate and caspase-9 inhibitor z-LEDH-fmk in experimental spinal cord injury. — PubMed · 2013 · Journal Article
- Effects of low-dose methotrexate in spinal cord injury in rats. — PubMed · 2013 · Journal Article
- The dose-dependent neuroprotective effect of alpha-lipoic acid in experimental spinal cord injury. — PubMed · 2013 · Comparative Study
- Updates in the management of the small animal patient with neurologic trauma. — PubMed · 2013 · Journal Article
- Resveratrol protects spinal cord dorsal column from hypoxic injury by activating Nrf-2. — PubMed · 2013 · Journal Article
- Beneficial effects of hydrogen-rich saline against spinal cord ischemia-reperfusion injury in rabbits. — PubMed · 2013 · Journal Article
- NDGA reduces secondary damage after spinal cord injury in rats via anti-inflammatory effects. — PubMed · 2013 · Journal Article
- Hyperbaric oxygen therapy provides neuroprotection following spinal cord injury in a rat model. — PubMed · 2013 · Journal Article
- Effects of combining methylprednisolone with rolipram on functional recovery in adult rats following spinal cord injury. — PubMed · 2013 · Journal Article
- The neuroprotective mechanism of puerarin treatment of acute spinal cord injury in rats. — PubMed · 2013 · Journal Article
- Granulocyte colony-stimulating factor improves alternative activation of microglia under microenvironment of spinal cord injury. — PubMed · 2013 · Journal Article
- Butein inhibits NF-κB activation and reduces infiltration of inflammatory cells and apoptosis after spinal cord injury in rats. — PubMed · 2013 · Journal Article
- Minocycline inhibited the pro-apoptotic effect of microglia on neural progenitor cells and protected their neuronal differentiation in vitro. — PubMed · 2013 · Journal Article
- Protective effect of low molecular weight polyethylene glycol on the repair of experimentally damaged neural membranes in rat's spinal cord. — PubMed · 2013 · Journal Article
- Therapeutic window for combination therapy of A91 peptide and glutathione allows delayed treatment after spinal cord injury. — PubMed · 2013 · Journal Article
- Efficacy of iloprost and montelukast combination on spinal cord ischemia/reperfusion injury in a rat model. — PubMed · 2013 · Evaluation Study
- Effect of melatonin on the functional recovery from experimental traumatic compression of the spinal cord. — PubMed · 2013 · Journal Article
- Expressions of C5a and its receptor CD88 after spinal cord injury in C3-deficient mice. — PubMed · 2013 · Journal Article
- Gua Lou Gui Zhi decoction exerts neuroprotective effects on post-stroke spasticity via the modulation of glutamate levels and AMPA receptor expression. — PubMed · 2013 · Journal Article
- Intrathecal epigallocatechin gallate treatment improves functional recovery after spinal cord injury by upregulating the expression of BDNF and GDNF. — PubMed · 2013 · Journal Article
- Lipopolysaccharide preconditioning attenuates neuroapoptosis and improves functional recovery through activation of Nrf2 in traumatic spinal cord injury rats. — PubMed · 2013 · Journal Article
- Neuroprotective effect of cocaine- and amphetamine-regulated transcript peptide in spinal cord injury in mice. — PubMed · 2013 · Journal Article
- The effect of methylprednisolone intravenous infusion on the expression of ciliary neurotrophic factor in a rat spinal cord injury model. — PubMed · 2013 · Journal Article
- Delayed post-injury administration of riluzole is neuroprotective in a preclinical rodent model of cervical spinal cord injury. — PubMed · 2013 · Journal Article
- Microglia response and in vivo therapeutic potential of methylprednisolone-loaded dendrimer nanoparticles in spinal cord injury. — PubMed · 2013 · Journal Article
- AT2-receptor stimulation enhances axonal plasticity after spinal cord injury by upregulating BDNF expression. — PubMed · 2013 · Journal Article
- Connexin43 mimetic peptide is neuroprotective and improves function following spinal cord injury. — PubMed · 2013 · Journal Article
- Mn (III) tetrakis (4-benzoic acid) porphyrin scavenges reactive species, reduces oxidative stress, and improves functional recovery after experimental spinal cord injury in rats: comparison with methylprednisolone. — PubMed · 2013 · Comparative Study
- Simvastatin ameliorates cauda equina compression injury in a rat model of lumbar spinal stenosis. — PubMed · 2013 · Journal Article
- Transgenic mice with high endogenous omega-3 fatty acids are protected from spinal cord injury. — PubMed · 2013 · Journal Article
- Molecular evidence for the involvement of PPAR-δ and PPAR-γ in anti-inflammatory and neuroprotective activities of palmitoylethanolamide after spinal cord trauma. — PubMed · 2013 · Journal Article
- Sialidase, chondroitinase ABC, and combination therapy after spinal cord contusion injury. — PubMed · 2013 · Journal Article
- The dual cyclooxygenase/5-lipoxygenase inhibitor licofelone attenuates p-glycoprotein-mediated drug resistance in the injured spinal cord. — PubMed · 2013 · Journal Article
- Absence of IL-1β positively affects neurological outcome, lesion development and axonal plasticity after spinal cord injury. — PubMed · 2013 · Journal Article
- AR-A014418 as a glycogen synthase kinase-3 inhibitor: anti-apoptotic and therapeutic potential in experimental spinal cord injury. — PubMed · 2013 · Journal Article
- A simple and effective semi-invasive method for inducing local hypothermia in rat spinal cord. — PubMed · 2013 · Journal Article
- Cholinergic neuron-like cells derived from bone marrow stromal cells induced by tricyclodecane-9-yl-xanthogenate promote functional recovery and neural protection after spinal cord injury. — PubMed · 2013 · Journal Article
- Effects of tetramethylpyrazine on microglia activation in spinal cord compression injury of mice. — PubMed · 2013 · Journal Article
- Multifaceted effects of rapamycin on functional recovery after spinal cord injury in rats through autophagy promotion, anti-inflammation, and neuroprotection. — PubMed · 2013 · Journal Article
- Neuroprotective effect of acute interferon-beta 1B treatment after spinal cord injury. — PubMed · 2013 · Journal Article
- Neuroprotective effects of raloxifene on experimental spinal cord injury in rats. — PubMed · 2013 · Journal Article
- Overexpression of melatonin membrane receptors increases calcium-binding proteins and protects VSC4.1 motoneurons from glutamate toxicity through multiple mechanisms. — PubMed · 2013 · Journal Article
- Rescue of injured motoneurones by grafted neuroectodermal stem cells: effect of the location of graft. — PubMed · 2013 · Journal Article
- The comparison of neuroprotective effects of intrathecal dexmedetomidine and metilprednisolone in spinal cord injury. — PubMed · 2013 · Journal Article
- The neuroprotective effects of rituximab in rat spinal cord injury model: an immunohistochemical study. — PubMed · 2013 · Journal Article
- The retrograde delivery of adenovirus vector carrying the gene for brain-derived neurotrophic factor protects neurons and oligodendrocytes from apoptosis in the chronically compressed spinal cord of twy/twy mice. — PubMed · 2012 · Journal Article
- Comparison of mesenchymal stem cells derived from fat, bone marrow, Wharton's jelly, and umbilical cord blood for treating spinal cord injuries in dogs. — PubMed · 2012 · Comparative Study
- Electro-acupuncture upregulates CGRP expression after rat spinal cord transection. — PubMed · 2012 · Journal Article
- Etanercept treatment enhances clinical and neuroelectrophysiological recovery in partial spinal cord injury. — PubMed · 2012 · Journal Article
- G-protein coupled estrogen receptor 1 mediated estrogenic neuroprotection against spinal cord injury. — PubMed · 2012 · Journal Article
- G protein-coupled estrogen receptor: a new therapeutic target in stroke and traumatic brain/spinal cord injury? — PubMed · 2012 · Editorial
- Neuroprotective effects of hypothermia after spinal cord injury in rats: comparative study between epidural hypothermia and systemic hypothermia. — PubMed · 2012 · Comparative Study
Where this was looked for, and when
The latest collection walk and the accumulated shelf have different scopes. A zero applies only to that source query and its date window; older records may remain on the shelf. It does not mean no research exists.
| ClinicalTrials.gov | latest collection walk returned no records | asked on 2026-10-05 Collection window: 2026-09-16 – 2026-10-05 | matched in this collection walk 0 · accumulated records across collection walks 6 · still to fetch in this walk 0 | aim: every record matching this question |
|---|---|---|---|---|
| Crossref | asked, and it answered | asked on 2026-09-16 Collection window: all dates before the end date – 2026-09-16 | matched in this collection walk 1230843 · accumulated records across collection walks 50 | aim: a sample of the most relevant records. This source ranks a bag of words, so its own total is the size of the corpus that shares some of them, never a set still owed. |
| PubMed | asked, and it answered | asked on 2026-09-17 Collection window: all dates before the end date – 2026-09-17 | matched in this collection walk 3744 · accumulated records across collection walks 3744 · still to fetch in this walk 0 | aim: every record matching this question |
The question asked
- ClinicalTrials.gov
("neuroprotection" OR "secondary injury") - Crossref
spinal cord injury neuroprotection secondary injury - PubMed
("Spinal Cord Injuries"[MeSH Terms] OR "spinal cord injury"[Title/Abstract] OR "spinal cord injuries"[Title/Abstract] OR "spinal cord trauma"[Title/Abstract]) AND ("Neuroprotection"[MeSH Terms] OR "Neuroprotective Agents"[MeSH Terms] OR "neuroprotection"[Title/Abstract] OR "secondary injury"[Title/Abstract])