A subject this map covers
Neuroprotection
What belongs here
Attempts to stop the second, delayed wave of damage in the first hours and days.
What does not belong here, however close it looks
Restoring function lost months earlier is repair, not neuroprotection.
What has been looked at
Counted from what the sources catalogue, not from reading the work. It says how much exists and over what span of years — never what any of it found.
- Registered or indexed as work in people: 1169 records · 1978–2027
- Indexed as work in animals: 1885 records · 1977–2026
- Indexed as laboratory work: 80 records · 1996–2026
- The source has not said who or what was studied: 572 records · 1991–2026
- No matching published catalogue records are linked above. Human-review status must be checked on the evidence itself.
Published in this map
Catalogue records matching this subject. Publication here does not establish human review, measured results or effectiveness. Open a record to inspect its sources and evidence.
No published catalogue records match this subject yet.
This is a result within this map, not a claim that no research exists. The source records below can help you continue searching.
Found in the scientific sources, not yet checked
Titles and identifiers as the sources publish them. Nobody here has read these papers, and nothing on this shelf is a result, a recommendation or evidence that anything works. Each line opens the original.
3706 records
This grouping is the source's own cataloguing, not a reading of the paper. It says where a record was filed, not what it found.
Indexed as work in animals
- Deletion of endoplasmic reticulum stress-induced CHOP protects microvasculature post-spinal cord injury. — PubMed · 2012 · Journal Article
- Neuroprotective effects of curculigoside against NMDA-induced neuronal excitoxicity in vitro. — PubMed · 2012 · Journal Article
- Neuroprotective effects of sulforaphane after contusive spinal cord injury. — PubMed · 2012 · Journal Article
- Selective gelatinase inhibitor neuroprotective agents cross the blood-brain barrier. — PubMed · 2012 · Journal Article
- A study of the potential neuroprotective effect of riluzole on locomotor networks of the neonatal rat spinal cord in vitro damaged by excitotoxicity. — PubMed · 2012 · Journal Article
- FM19G11 favors spinal cord injury regeneration and stem cell self-renewal by mitochondrial uncoupling and glucose metabolism induction. — PubMed · 2012 · Journal Article
- Characterization of inflammatory gene expression and galectin-3 function after spinal cord injury in mice. — PubMed · 2012 · Journal Article
- A CD11d monoclonal antibody treatment reduces tissue injury and improves neurological outcome after fluid percussion brain injury in rats. — PubMed · 2012 · Journal Article
- Increase in phosphorylation of PDK1 and cell survival after acute spinal cord injury. — PubMed · 2012 · Journal Article
- Stromal cell-derived factor-1 alpha (SDF-1α) improves neural recovery after spinal cord contusion in rats. — PubMed · 2012 · Journal Article
- Mn (III) tetrakis (4-benzoic acid) porphyrin protects against neuronal and glial oxidative stress and death after spinal cord injury. — PubMed · 2012 · Journal Article
- The role of mTOR signaling pathway in spinal cord injury. — PubMed · 2012 · Journal Article
- Neuroprotective effects of testosterone on motoneuron and muscle morphology following spinal cord injury. — PubMed · 2012 · Journal Article
- Postinjury administration of 17β-estradiol induces protection in the gray and white matter with associated functional recovery after cervical spinal cord injury in male rats. — PubMed · 2012 · Journal Article
- Dietary therapy to promote neuroprotection in chronic spinal cord injury. — PubMed · 2012 · Comparative Study
- [Effect of aminoguanidine on spinal cord edema of acute spinal cord injury in rats]. — PubMed · 2012 · English Abstract
- Effects of retrograde gene transfer of brain-derived neurotrophic factor in the rostral spinal cord of a compression model in rat. — PubMed · 2012 · Journal Article
- Fluoxetine inhibits matrix metalloprotease activation and prevents disruption of blood-spinal cord barrier after spinal cord injury. — PubMed · 2012 · Journal Article
- Passive immunization with myelin basic protein activated T cells suppresses axonal dieback but does not promote axonal regeneration following spinal cord hemisection in adult rats. — PubMed · 2012 · Journal Article
- Inhibition of EGFR/MAPK signaling reduces microglial inflammatory response and the associated secondary damage in rats after spinal cord injury. — PubMed · 2012 · Journal Article
- Simvastatin mobilizes bone marrow stromal cells migrating to injured areas and promotes functional recovery after spinal cord injury in the rat. — PubMed · 2012 · Journal Article
- Myeloperoxidase exacerbates secondary injury by generating highly reactive oxygen species and mediating neutrophil recruitment in experimental spinal cord injury. — PubMed · 2012 · Journal Article
- 17β-estradiol attenuates neural cell apoptosis through inhibition of JNK phosphorylation in SCI rats and excitotoxicity induced by glutamate in vitro. — PubMed · 2012 · Journal Article
- Molecular mechanism of Jmjd3-mediated interleukin-6 gene regulation in endothelial cells underlying spinal cord injury. — PubMed · 2012 · Journal Article
- Neuroprotective effect of vaccination with autoantigen-pulsed dendritic cells after spinal cord injury. — PubMed · 2012 · Journal Article
- Neuroprotective effects of racemic ketamine and (S)-ketamine on spinal cord injury in rat. — PubMed · 2012 · Comparative Study
- The role of pro- and anti-inflammatory cytokines in the pathogenesis of spontaneous canine CNS diseases. — PubMed · 2012 · Journal Article
- Docosahexaenoic acid, but not eicosapentaenoic acid, reduces the early inflammatory response following compression spinal cord injury in the rat. — PubMed · 2012 · Journal Article
- Fate of transplanted bone marrow derived mesenchymal stem cells following spinal cord injury in rats by transplantation routes. — PubMed · 2012 · Comparative Study
- [Neuroprotective effects of recombinant adeno-associated virus expressing vascular endothelial growth factor on rat traumatic spinal cord injury and its mechanism]. — PubMed · 2012 · English Abstract
- Response to 'The administration of high-dose methylprednisolone for 24 h reduced muscle size and increased atrophy-related gene expression in spinal cord-injured rats'. — PubMed · 2012 · Letter
- Specific inhibition of the JNK pathway promotes locomotor recovery and neuroprotection after mouse spinal cord injury. — PubMed · 2012 · Journal Article
- Valproic acid attenuates blood-spinal cord barrier disruption by inhibiting matrix metalloprotease-9 activity and improves functional recovery after spinal cord injury. — PubMed · 2012 · Journal Article
- Acetyl-L-carnitine treatment following spinal cord injury improves mitochondrial function correlated with remarkable tissue sparing and functional recovery. — PubMed · 2012 · Journal Article
- The effects of a polyphenol present in olive oil, oleuropein aglycone, in an experimental model of spinal cord injury in mice. — PubMed · 2012 · Journal Article
- Cell-based transplantation strategies to promote plasticity following spinal cord injury. — PubMed · 2012 · Journal Article
- Delayed cell cycle pathway modulation facilitates recovery after spinal cord injury. — PubMed · 2012 · Journal Article
- Ethyl pyruvate promotes spinal cord repair by ameliorating the glial microenvironment. — PubMed · 2012 · Journal Article
- Functional recovery after spinal cord injury in dogs treated with a combination of Matrigel and neural-induced adipose-derived mesenchymal Stem cells. — PubMed · 2012 · Journal Article
- Recovery from spinal cord injury using naturally occurring antiinflammatory compound curcumin: laboratory investigation. — PubMed · 2012 · Journal Article
- The dark side of neuroplasticity. — PubMed · 2012 · Journal Article
- Multiple drug delivery hydrogel system for spinal cord injury repair strategies. — PubMed · 2012 · Journal Article
- Metallothionein-II improves motor function recovery and increases spared tissue after spinal cord injury in rats. — PubMed · 2012 · Journal Article
- Cannabidiol-treated rats exhibited higher motor score after cryogenic spinal cord injury. — PubMed · 2012 · Journal Article
- Mechanisms of injury and emergency care of acute spinal cord injury in dogs and cats. — PubMed · 2012 · Journal Article
- MicroRNA 486 is a potentially novel target for the treatment of spinal cord injury. — PubMed · 2012 · Journal Article
- Activation of the nuclear factor E2-related factor 2/antioxidant response element pathway is neuroprotective after spinal cord injury. — PubMed · 2012 · Journal Article
- Amphetamine-enhanced motor training after cervical contusion injury. — PubMed · 2012 · Journal Article
- Rapamycin promotes autophagy and reduces neural tissue damage and locomotor impairment after spinal cord injury in mice. — PubMed · 2012 · Journal Article
- Autophagy is activated in injured neurons and inhibited by methylprednisolone after experimental spinal cord injury. — PubMed · 2012 · Journal Article
- Critical role of connexin 43 in secondary expansion of traumatic spinal cord injury. — PubMed · 2012 · Comparative Study
- Targeting IKK/NF-κB pathway reduces infiltration of inflammatory cells and apoptosis after spinal cord injury in rats. — PubMed · 2012 · Journal Article
- Differential detection and distribution of microglial and hematogenous macrophage populations in the injured spinal cord of lys-EGFP-ki transgenic mice. — PubMed · 2012 · Journal Article
- Immunization with A91 peptide or copolymer-1 reduces the production of nitric oxide and inducible nitric oxide synthase gene expression after spinal cord injury. — PubMed · 2012 · Journal Article
- Docosahexaenoic acid pretreatment confers protection and functional improvements after acute spinal cord injury in adult rats. — PubMed · 2012 · Journal Article
- A reassessment of a classic neuroprotective combination therapy for spinal cord injured rats: LPS/pregnenolone/indomethacin. — PubMed · 2012 · Comparative Study
- A reassessment of LPS/indomethacin/pregnenolone combination therapy after spinal cord injury in rats. — PubMed · 2012 · Journal Article
- A reassessment of P2X7 receptor inhibition as a neuroprotective strategy in rat models of contusion injury. — PubMed · 2012 · Comparative Study
- Potential long-term benefits of acute hypothermia after spinal cord injury: assessments with somatosensory-evoked potentials. — PubMed · 2012 · Comparative Study
- Glial activation in the spinal ventral horn caudal to cervical injury. — PubMed · 2012 · Journal Article
Where this was looked for, and when
The latest collection walk and the accumulated shelf have different scopes. A zero applies only to that source query and its date window; older records may remain on the shelf. It does not mean no research exists.
| ClinicalTrials.gov | latest collection walk returned no records | asked on 2026-10-05 Collection window: 2026-09-16 – 2026-10-05 | matched in this collection walk 0 · accumulated records across collection walks 6 · still to fetch in this walk 0 | aim: every record matching this question |
|---|---|---|---|---|
| Crossref | asked, and it answered | asked on 2026-09-16 Collection window: all dates before the end date – 2026-09-16 | matched in this collection walk 1230843 · accumulated records across collection walks 50 | aim: a sample of the most relevant records. This source ranks a bag of words, so its own total is the size of the corpus that shares some of them, never a set still owed. |
| PubMed | asked, and it answered | asked on 2026-09-17 Collection window: all dates before the end date – 2026-09-17 | matched in this collection walk 3744 · accumulated records across collection walks 3744 · still to fetch in this walk 0 | aim: every record matching this question |
The question asked
- ClinicalTrials.gov
("neuroprotection" OR "secondary injury") - Crossref
spinal cord injury neuroprotection secondary injury - PubMed
("Spinal Cord Injuries"[MeSH Terms] OR "spinal cord injury"[Title/Abstract] OR "spinal cord injuries"[Title/Abstract] OR "spinal cord trauma"[Title/Abstract]) AND ("Neuroprotection"[MeSH Terms] OR "Neuroprotective Agents"[MeSH Terms] OR "neuroprotection"[Title/Abstract] OR "secondary injury"[Title/Abstract])