A subject this map covers
Neuroprotection
What belongs here
Attempts to stop the second, delayed wave of damage in the first hours and days.
What does not belong here, however close it looks
Restoring function lost months earlier is repair, not neuroprotection.
What has been looked at
Counted from what the sources catalogue, not from reading the work. It says how much exists and over what span of years — never what any of it found.
- Registered or indexed as work in people: 1169 records · 1978–2027
- Indexed as work in animals: 1885 records · 1977–2026
- Indexed as laboratory work: 80 records · 1996–2026
- The source has not said who or what was studied: 572 records · 1991–2026
- No matching published catalogue records are linked above. Human-review status must be checked on the evidence itself.
Published in this map
Catalogue records matching this subject. Publication here does not establish human review, measured results or effectiveness. Open a record to inspect its sources and evidence.
No published catalogue records match this subject yet.
This is a result within this map, not a claim that no research exists. The source records below can help you continue searching.
Found in the scientific sources, not yet checked
Titles and identifiers as the sources publish them. Nobody here has read these papers, and nothing on this shelf is a result, a recommendation or evidence that anything works. Each line opens the original.
3706 records
This grouping is the source's own cataloguing, not a reading of the paper. It says where a record was filed, not what it found.
Indexed as work in animals
- Acute leptin treatment enhances functional recovery after spinal cord injury. — PubMed · 2012 · Journal Article
- BB14, a Nerve Growth Factor (NGF)-like peptide shown to be effective in reducing reactive astrogliosis and restoring synaptic homeostasis in a rat model of peripheral nerve injury. — PubMed · 2012 · Journal Article
- Beneficial effects of endogenous and exogenous melatonin on neural reconstruction and functional recovery in an animal model of spinal cord injury. — PubMed · 2012 · Journal Article
- CIBZ, a novel BTB domain-containing protein, is involved in mouse spinal cord injury via mitochondrial pathway independent of p53 gene. — PubMed · 2012 · Journal Article
- Comparative effects of glibenclamide and riluzole in a rat model of severe cervical spinal cord injury. — PubMed · 2012 · Comparative Study
- Delayed granulocyte colony-stimulating factor treatment promotes functional recovery in rats with severe contusive spinal cord injury. — PubMed · 2012 · Journal Article
- Development of protective autoimmunity by immunization with a neural-derived peptide is ineffective in severe spinal cord injury. — PubMed · 2012 · Journal Article
- Direct isolation and RNA-seq reveal environment-dependent properties of engrafted neural stem/progenitor cells. — PubMed · 2012 · Journal Article
- Early endogenous activation of CB1 and CB2 receptors after spinal cord injury is a protective response involved in spontaneous recovery. — PubMed · 2012 · Journal Article
- Effect of curcumin on lipid peroxidation, early ultrastructural findings and neurological recovery after experimental spinal cord contusion injury in rats. — PubMed · 2012 · Journal Article
- Effects of valproic acid, a histone deacetylase inhibitor, on improvement of locomotor function in rat spinal cord injury based on epigenetic science. — PubMed · 2012 · Journal Article
- Inhibition of inflammation and oxidative stress by Angelica dahuricae radix extract decreases apoptotic cell death and improves functional recovery after spinal cord injury. — PubMed · 2012 · Journal Article
- Neuroprotective effect of oleuropein following spinal cord injury in rats. — PubMed · 2012 · Journal Article
- Neuroprotective effects of N-acetyl-cysteine and acetyl-L-carnitine after spinal cord injury in adult rats. — PubMed · 2012 · Journal Article
- Neuroprotective efficacy of quinazoline type phosphodiesterase 7 inhibitors in cellular cultures and experimental stroke model. — PubMed · 2012 · Journal Article
- Neuroserpin upregulates in the early period of sustained spinal cord compression. — PubMed · 2012 · Journal Article
- Protective effects of erythropoietin in experimental spinal cord injury by reducing the C/EBP-homologous protein expression. — PubMed · 2012 · Journal Article
- Rodent spinal cord injury model and application of neurotrophic factors for neuroprotection. — PubMed · 2012 · Journal Article
- Systemic bisperoxovanadium activates Akt/mTOR, reduces autophagy, and enhances recovery following cervical spinal cord injury. — PubMed · 2012 · Journal Article
- Tanshinone IIA attenuates the inflammatory response and apoptosis after traumatic injury of the spinal cord in adult rats. — PubMed · 2012 · Journal Article
- The therapeutic profile of rolipram, PDE target and mechanism of action as a neuroprotectant following spinal cord injury. — PubMed · 2012 · Journal Article
- Topiramate treatment is neuroprotective and reduces oligodendrocyte loss after cervical spinal cord injury. — PubMed · 2012 · Comparative Study
- [Transfection of exogenous gene: Lac Z into spinal cord of SD rats and its protein expression:an in vivo study]. — PubMed · 2012 · English Abstract
- [Inhibitory effect of chondroitinase ABC on ephrin A4 expression after spinal cord injury in rats]. — PubMed · 2011 · English Abstract
- The ameliorating effect of dantrolene on the morphology of urinary bladder in spinal cord injured rats. — PubMed · 2011 · Journal Article
- Acute administration of AMPA/Kainate blocker combined with delayed transplantation of neural precursors improves lower urinary tract function in spinal injured rats. — PubMed · 2011 · Journal Article
- Effect of heparin following cervical spinal cord injuries in rats. — PubMed · 2011 · Journal Article
- Low dose estrogen prevents neuronal degeneration and microglial reactivity in an acute model of spinal cord injury: effect of dosing, route of administration, and therapy delay. — PubMed · 2011 · Journal Article
- Neuroprotective effects of granulocyte colony-stimulating factor and relationship to promotion of angiogenesis after spinal cord injury in rats: laboratory investigation. — PubMed · 2011 · Journal Article
- Neuroprotective effects of gabapentin on spinal cord ischemia-reperfusion injury in rabbits. — PubMed · 2011 · Comparative Study
- Effects of palmitoylethanolamide on release of mast cell peptidases and neurotrophic factors after spinal cord injury. — PubMed · 2011 · Journal Article
- Neuroprotective and growth-promoting effects of bone marrow stromal cells after cervical spinal cord injury in adult rats. — PubMed · 2011 · Journal Article
- Neuroprotective effects of genistein in VSC4.1 motoneurons exposed to activated microglial cytokines. — PubMed · 2011 · Journal Article
- Role of acid-sensing ion channel 1a in the secondary damage of traumatic spinal cord injury. — PubMed · 2011 · Journal Article
- The administration of high-dose methylprednisolone for 24 h reduced muscle size and increased atrophy-related gene expression in spinal cord-injured rats. — PubMed · 2011 · Journal Article
- Treatment of experimental spinal cord injury with 3β-methoxy-pregnenolone. — PubMed · 2011 · Journal Article
- Deficient CX3CR1 signaling promotes recovery after mouse spinal cord injury by limiting the recruitment and activation of Ly6Clo/iNOS+ macrophages. — PubMed · 2011 · Journal Article
- S-nitrosoglutathione reduces oxidative injury and promotes mechanisms of neurorepair following traumatic brain injury in rats. — PubMed · 2011 · Journal Article
- A combination immunomodulatory treatment promotes neuroprotection and locomotor recovery after contusion SCI. — PubMed · 2011 · Journal Article
- Amiloride improves locomotor recovery after spinal cord injury. — PubMed · 2011 · Journal Article
- Rosuvastatin, a new generation 3-hydroxy-3-methylglutaryl coenzyme a reductase inhibitor, reduces ischemia/reperfusion-induced spinal cord tissue injury in rats. — PubMed · 2011 · Journal Article
- A selective phosphodiesterase-4 inhibitor reduces leukocyte infiltration, oxidative processes, and tissue damage after spinal cord injury. — PubMed · 2011 · Journal Article
- Preclinical use of longitudinal MRI for screening the efficacy of S-nitrosoglutathione in treating spinal cord injury. — PubMed · 2011 · Journal Article
- [Protective effect of olfactory ensheathing cells in combination with intrathecal injection of vascular endothelial growth factor on injured spinal cord in rats]. — PubMed · 2011 · English Abstract
- Early administration of L-arginine in experimental acute spinal cord injury impairs long-term motor function recovery. — PubMed · 2011 · Comparative Study
- Olfactory ensheathing cell transplantation into spinal cord prolongs the survival of mutant SOD1(G93A) ALS rats through neuroprotection and remyelination. — PubMed · 2011 · Journal Article
- Selective adenosine A2A receptor agonists and antagonists protect against spinal cord injury through peripheral and central effects. — PubMed · 2011 · Journal Article
- Curcumin provides neuroprotection after spinal cord injury. — PubMed · 2011 · Journal Article
- Effect of vascular endothelial growth factor treatment in experimental traumatic spinal cord injury: in vivo longitudinal assessment. — PubMed · 2011 · Journal Article
- Neuroprotective effects of almond skins in experimental spinal cord injury. — PubMed · 2011 · Comparative Study
- Signaling pathways of ATP-induced PGE2 release in spinal cord astrocytes are EGFR transactivation-dependent. — PubMed · 2011 · Journal Article
- The effect of irradiation and methylprednisolone in spinal cord injured rats. — PubMed · 2011 · Journal Article
- Inhibition of cPLA2 activation by Ginkgo biloba extract protects spinal cord neurons from glutamate excitotoxicity and oxidative stress-induced cell death. — PubMed · 2011 · Journal Article
- Meloxicam exerts neuroprotection on spinal cord trauma in rats. — PubMed · 2011 · Comparative Study
- Neuroprotective features of mesenchymal stem cells. — PubMed · 2011 · Journal Article
- Pregabalin as a neuroprotector after spinal cord injury in rats: biochemical analysis and effect on glial cells. — PubMed · 2011 · Journal Article
- Resveratrol improves neuron protection and functional recovery in rat model of spinal cord injury. — PubMed · 2011 · Comparative Study
- Effects of dihydroxylphenyl lactic acid on inflammatory responses in spinal cord injury. — PubMed · 2011 · Journal Article
- Caffeic acid phenethyl ester reduces spinal cord injury-evoked locomotor dysfunction. — PubMed · 2011 · Journal Article
- Effect of Apocynin, an inhibitor of NADPH oxidase, in the inflammatory process induced by an experimental model of spinal cord injury. — PubMed · 2011 · Journal Article
Where this was looked for, and when
The latest collection walk and the accumulated shelf have different scopes. A zero applies only to that source query and its date window; older records may remain on the shelf. It does not mean no research exists.
| ClinicalTrials.gov | latest collection walk returned no records | asked on 2026-10-05 Collection window: 2026-09-16 – 2026-10-05 | matched in this collection walk 0 · accumulated records across collection walks 6 · still to fetch in this walk 0 | aim: every record matching this question |
|---|---|---|---|---|
| Crossref | asked, and it answered | asked on 2026-09-16 Collection window: all dates before the end date – 2026-09-16 | matched in this collection walk 1230843 · accumulated records across collection walks 50 | aim: a sample of the most relevant records. This source ranks a bag of words, so its own total is the size of the corpus that shares some of them, never a set still owed. |
| PubMed | asked, and it answered | asked on 2026-09-17 Collection window: all dates before the end date – 2026-09-17 | matched in this collection walk 3744 · accumulated records across collection walks 3744 · still to fetch in this walk 0 | aim: every record matching this question |
The question asked
- ClinicalTrials.gov
("neuroprotection" OR "secondary injury") - Crossref
spinal cord injury neuroprotection secondary injury - PubMed
("Spinal Cord Injuries"[MeSH Terms] OR "spinal cord injury"[Title/Abstract] OR "spinal cord injuries"[Title/Abstract] OR "spinal cord trauma"[Title/Abstract]) AND ("Neuroprotection"[MeSH Terms] OR "Neuroprotective Agents"[MeSH Terms] OR "neuroprotection"[Title/Abstract] OR "secondary injury"[Title/Abstract])