A subject this map covers
Neuroprotection
What belongs here
Attempts to stop the second, delayed wave of damage in the first hours and days.
What does not belong here, however close it looks
Restoring function lost months earlier is repair, not neuroprotection.
What has been looked at
Counted from what the sources catalogue, not from reading the work. It says how much exists and over what span of years — never what any of it found.
- Registered or indexed as work in people: 1169 records · 1978–2027
- Indexed as work in animals: 1885 records · 1977–2026
- Indexed as laboratory work: 80 records · 1996–2026
- The source has not said who or what was studied: 572 records · 1991–2026
- No matching published catalogue records are linked above. Human-review status must be checked on the evidence itself.
Published in this map
Catalogue records matching this subject. Publication here does not establish human review, measured results or effectiveness. Open a record to inspect its sources and evidence.
No published catalogue records match this subject yet.
This is a result within this map, not a claim that no research exists. The source records below can help you continue searching.
Found in the scientific sources, not yet checked
Titles and identifiers as the sources publish them. Nobody here has read these papers, and nothing on this shelf is a result, a recommendation or evidence that anything works. Each line opens the original.
3706 records
This grouping is the source's own cataloguing, not a reading of the paper. It says where a record was filed, not what it found.
Indexed as work in animals
- Effects of continuous intravenous infusion of MCI-186 on functional recovery after spinal cord injury in rats. — PubMed · 2011 · Journal Article
- Estrogen receptor agonists and estrogen attenuate TNF-α-induced apoptosis in VSC4.1 motoneurons. — PubMed · 2011 · Journal Article
- Ion channels on microglia: therapeutic targets for neuroprotection. — PubMed · 2011 · Journal Article
- Proteins conjugated to poly(butyl cyanoacrylate) nanoparticles as potential neuroprotective agents. — PubMed · 2011 · Journal Article
- Hypoxia-induced expression of VEGF in the organotypic spinal cord slice culture. — PubMed · 2011 · Journal Article
- 2-Methoxyestradiol inhibits the up-regulation of AQP4 and AQP1 expression after spinal cord injury. — PubMed · 2011 · Journal Article
- Hyaluronan oligosaccharides promote functional recovery after spinal cord injury in rats. — PubMed · 2011 · Journal Article
- Simvastatin treatment improves functional recovery after experimental spinal cord injury by upregulating the expression of BDNF and GDNF. — PubMed · 2011 · Journal Article
- A murine model of hypertonic saline as a treatment for acute spinal cord injury: effects on autonomic outcome. — PubMed · 2011 · Journal Article
- Attenuation of spinal cord ischemia and reperfusion injury by erythropoietin. — PubMed · 2011 · Journal Article
- Comparative neuroprotective effects of methylprednisolone and rosiglitazone, a peroxisome proliferator-activated receptor-γ following spinal cord injury. — PubMed · 2011 · Comparative Study
- Ghrelin alleviates spinal cord injury in rats via its anti-inflammatory effects. — PubMed · 2011 · Journal Article
- Metamorphosis and the regenerative capacity of spinal cord axons in Xenopus laevis. — PubMed · 2011 · Journal Article
- Protective effects of edaravone on experimental spinal cord injury in rats. — PubMed · 2011 · Comparative Study
- The neuroprotective effects of Reg-2 following spinal cord transection injury. — PubMed · 2011 · Comparative Study
- Wind-up of stretch reflexes as a measure of spasticity in chronic spinalized rats: The effects of passive exercise and modafinil. — PubMed · 2011 · Journal Article
- Selected changes in spinal cord morphology after T4 transection and olfactory ensheathing cell transplantation. — PubMed · 2010 · Journal Article
- Effect of granulocyte-colony stimulating factor on spinal cord tissue after experimental contusion injury. — PubMed · 2010 · Journal Article
- Neuroprotective effects of infliximab in experimental spinal cord ischemic injury. — PubMed · 2010 · Journal Article
- Long descending cervical propriospinal neurons differ from thoracic propriospinal neurons in response to low thoracic spinal injury. — PubMed · 2010 · Comparative Study
- 17β-estradiol protects Schwann cells against H2O2-induced cytotoxicity and increases transplanted Schwann cell survival in a cervical hemicontusion spinal cord injury model. — PubMed · 2010 · Comparative Study
- Cellular response after crush injury in adult zebrafish spinal cord. — PubMed · 2010 · Journal Article
- Magnesium in a polyethylene glycol formulation provides neuroprotection after unilateral cervical spinal cord injury. — PubMed · 2010 · Journal Article
- Potentializing the effects of GM1 by hyperbaric oxygen therapy in acute experimental spinal cord lesion in rats. — PubMed · 2010 · Evaluation Study
- Traumatic spinal cord injury alters angiogenic factors and TGF-beta1 that may affect vascular recovery. — PubMed · 2010 · Journal Article
- Neuroprotective effect of baicalin on compression spinal cord injury in rats. — PubMed · 2010 · Journal Article
- Docosahexaenoic acid prevents white matter damage after spinal cord injury. — PubMed · 2010 · Journal Article
- Evaluation of protective effects of the alpha lipoic acid after spinal cord injury: an animal study. — PubMed · 2010 · Journal Article
- Kainate-mediated excitotoxicity induces neuronal death in the rat spinal cord in vitro via a PARP-1 dependent cell death pathway (Parthanatos). — PubMed · 2010 · Journal Article
- Neuroprotective effects of tamoxifen on experimental spinal cord injury in rats. — PubMed · 2010 · Journal Article
- PPARγ agonist rosiglitazone is neuroprotective after traumatic spinal cord injury via anti-inflammatory in adult rats. — PubMed · 2010 · Journal Article
- Repetitive intrathecal VEGF(165) treatment has limited therapeutic effects after spinal cord injury in the rat. — PubMed · 2010 · Journal Article
- The acute administration of eicosapentaenoic acid is neuroprotective after spinal cord compression injury in rats. — PubMed · 2010 · Journal Article
- Acupuncture-mediated inhibition of inflammation facilitates significant functional recovery after spinal cord injury. — PubMed · 2010 · Journal Article
- A quadruped study on chitosan microspheres containing atorvastatin calcium: preparation, characterization, quantification and in-vivo application. — PubMed · 2010 · Journal Article
- Curcumin improves early functional results after experimental spinal cord injury. — PubMed · 2010 · Comparative Study
- Lack of neuroprotective effects of simvastatin and minocycline in a model of cervical spinal cord injury. — PubMed · 2010 · Journal Article
- The pathogenesis and treatment of acute spinal cord injuries in dogs. — PubMed · 2010 · Journal Article
- Effects of axon degeneration on oligodendrocyte lineage cells: dorsal rhizotomy evokes a repair response while axon degeneration rostral to spinal contusion induces both repair and apoptosis. — PubMed · 2010 · Journal Article
- Hydroxysafflor Yellow A protects spinal cords from ischemia/reperfusion injury in rabbits. — PubMed · 2010 · Journal Article
- Protective effects of angiotensin II type-1 receptor blockade with olmesartan on spinal cord ischemia-reperfusion injury: an experimental study on rats. — PubMed · 2010 · Journal Article
- Spinal microvascular expression of PV-1 is associated with inflammation, perivascular astrocyte loss, and diminished EC glucose transport potential in acute SCI. — PubMed · 2010 · Journal Article
- Treadmill running protects spinal cord contusion from secondary degeneration. — PubMed · 2010 · Journal Article
- Morphological changes of the neural cells after blast injury of spinal cord and neuroprotective effects of sodium beta-aescinate in rabbits. — PubMed · 2010 · Journal Article
- NCAM-mediated locomotor recovery from spinal cord contusion injury involves neuroprotection, axon regeneration, and synaptogenesis. — PubMed · 2010 · Journal Article
- The neuroprotective effects of fibronectin mats and fibronectin peptides following spinal cord injury in the rat. — PubMed · 2010 · Journal Article
- The effect of aminoguanidine on compression spinal cord injury in rats. — PubMed · 2010 · Journal Article
- Cortical overexpression of neuronal calcium sensor-1 induces functional plasticity in spinal cord following unilateral pyramidal tract injury in rat. — PubMed · 2010 · Journal Article
- Melatonin-analog, beta-methyl-6-chloromelatonin, supplementation in spinal cord injury. — PubMed · 2010 · Journal Article
- A combination of tumor necrosis factor-alpha and neuronal nitric oxide synthase antibodies applied topically over the traumatized spinal cord enhances neuroprotection and functional recovery in the rat. — PubMed · 2010 · Journal Article
- Cerebrolysin reduces blood-cerebrospinal fluid barrier permeability change, brain pathology, and functional deficits following traumatic brain injury in the rat. — PubMed · 2010 · Journal Article
- Citicoline and postconditioning provides neuroprotection in a rat model of ischemic spinal cord injury. — PubMed · 2010 · Journal Article
- Epidermal neural crest stem cell (EPI-NCSC)--mediated recovery of sensory function in a mouse model of spinal cord injury. — PubMed · 2010 · Journal Article
- Neuroprotective effects of gabapentin in experimental spinal cord injury. — PubMed · 2010 · Comparative Study
- Neuroprotective efficacy of estrogen in experimental spinal cord injury in rats. — PubMed · 2010 · Journal Article
- PEGylated interferon-beta modulates the acute inflammatory response and recovery when combined with forced exercise following cervical spinal contusion injury. — PubMed · 2010 · Journal Article
- Physiological low dose of estrogen-protected neurons in experimental spinal cord injury. — PubMed · 2010 · Journal Article
- The endocannabinoid 2-arachidonoylglycerol reduces lesion expansion and white matter damage after spinal cord injury. — PubMed · 2010 · Journal Article
- The hematopoietic factor granulocyte-colony stimulating factor improves outcome in experimental spinal cord injury. — PubMed · 2010 · Journal Article
- The LTB4-BLT1 axis mediates neutrophil infiltration and secondary injury in experimental spinal cord injury. — PubMed · 2010 · Journal Article
Where this was looked for, and when
The latest collection walk and the accumulated shelf have different scopes. A zero applies only to that source query and its date window; older records may remain on the shelf. It does not mean no research exists.
| ClinicalTrials.gov | latest collection walk returned no records | asked on 2026-10-05 Collection window: 2026-09-16 – 2026-10-05 | matched in this collection walk 0 · accumulated records across collection walks 6 · still to fetch in this walk 0 | aim: every record matching this question |
|---|---|---|---|---|
| Crossref | asked, and it answered | asked on 2026-09-16 Collection window: all dates before the end date – 2026-09-16 | matched in this collection walk 1230843 · accumulated records across collection walks 50 | aim: a sample of the most relevant records. This source ranks a bag of words, so its own total is the size of the corpus that shares some of them, never a set still owed. |
| PubMed | asked, and it answered | asked on 2026-09-17 Collection window: all dates before the end date – 2026-09-17 | matched in this collection walk 3744 · accumulated records across collection walks 3744 · still to fetch in this walk 0 | aim: every record matching this question |
The question asked
- ClinicalTrials.gov
("neuroprotection" OR "secondary injury") - Crossref
spinal cord injury neuroprotection secondary injury - PubMed
("Spinal Cord Injuries"[MeSH Terms] OR "spinal cord injury"[Title/Abstract] OR "spinal cord injuries"[Title/Abstract] OR "spinal cord trauma"[Title/Abstract]) AND ("Neuroprotection"[MeSH Terms] OR "Neuroprotective Agents"[MeSH Terms] OR "neuroprotection"[Title/Abstract] OR "secondary injury"[Title/Abstract])