A subject this map covers
Neuroprotection
What belongs here
Attempts to stop the second, delayed wave of damage in the first hours and days.
What does not belong here, however close it looks
Restoring function lost months earlier is repair, not neuroprotection.
What has been looked at
Counted from what the sources catalogue, not from reading the work. It says how much exists and over what span of years — never what any of it found.
- Registered or indexed as work in people: 1169 records · 1978–2027
- Indexed as work in animals: 1885 records · 1977–2026
- Indexed as laboratory work: 80 records · 1996–2026
- The source has not said who or what was studied: 572 records · 1991–2026
- No matching published catalogue records are linked above. Human-review status must be checked on the evidence itself.
Published in this map
Catalogue records matching this subject. Publication here does not establish human review, measured results or effectiveness. Open a record to inspect its sources and evidence.
No published catalogue records match this subject yet.
This is a result within this map, not a claim that no research exists. The source records below can help you continue searching.
Found in the scientific sources, not yet checked
Titles and identifiers as the sources publish them. Nobody here has read these papers, and nothing on this shelf is a result, a recommendation or evidence that anything works. Each line opens the original.
3706 records
This grouping is the source's own cataloguing, not a reading of the paper. It says where a record was filed, not what it found.
Indexed as work in animals
- Esmolol and landiolol, selective beta1-adrenoreceptor antagonists, provide neuroprotection against spinal cord ischemia and reperfusion in rats. — PubMed · 2010 · Journal Article
- Ginsenoside Rg1 promotes proliferation and neurotrophin expression of olfactory ensheathing cells. — PubMed · 2010 · Journal Article
- Neuroprotective effect of mesna (2-mercaptoethane sulfonate) against spinal cord ischemia/reperfusion injury in rabbits. — PubMed · 2010 · Journal Article
- NMDA receptor blockage with 2-amino-5-phosphonovaleric acid improves oxidative stress after spinal cord trauma in rats. — PubMed · 2010 · Journal Article
- Pretreatment with the ciclosporin derivative NIM811 reduces delayed neuronal death in the hippocampus after transient forebrain ischaemia. — PubMed · 2010 · Journal Article
- The effectiveness of dexmedetomidine in experimental spinal cord injury compared to methylprednisolone in rats. — PubMed · 2010 · Journal Article
- Ultrastructural changes in the liver after experimental spinal cord injury in rats: effects of methylprednisolone, immunoglobulin g and albumin. — PubMed · 2010 · Journal Article
- Effects of L-lysine monohydrochloride on insulin and blood glucose levels in spinal cord injured rats. — PubMed · 2010 · Journal Article
- Fenretinide promotes functional recovery and tissue protection after spinal cord contusion injury in mice. — PubMed · 2010 · Journal Article
- Effect of endogenous androgens on 17beta-estradiol-mediated protection after spinal cord injury in male rats. — PubMed · 2010 · Journal Article
- Effects of xenon on ischemic spinal cord injury in rabbits: a comparison with propofol. — PubMed · 2010 · Comparative Study
- Quercetin administration after spinal cord trauma changes S-100 levels. — PubMed · 2010 · Journal Article
- Tamoxifen alleviates irradiation-induced brain injury by attenuating microglial inflammatory response in vitro and in vivo. — PubMed · 2010 · Journal Article
- Protective effect of etomidate on spinal cord ischemia-reperfusion injury induced by aortic occlusion in rabbits. — PubMed · 2010 · Journal Article
- Protective effects of cold spinoplegia with fasudil against ischemic spinal cord injury in rabbits. — PubMed · 2010 · Journal Article
- A large-scale chemical screen for regulators of the arginase 1 promoter identifies the soy isoflavone daidzeinas a clinically approved small molecule that can promote neuronal protection or regeneration via a cAMP-independent pathway. — PubMed · 2010 · Journal Article
- Effects of epigallocatechin gallate on tissue protection and functional recovery after contusive spinal cord injury in rats. — PubMed · 2010 · Journal Article
- A retinoic acid receptor beta agonist (CD2019) overcomes inhibition of axonal outgrowth via phosphoinositide 3-kinase signalling in the injured adult spinal cord. — PubMed · 2010 · Journal Article
- Comparison of the effect of mexiletine and methylprednisolone on neural function and histopathological damage after transient spinal cord ischemia in rabbits. — PubMed · 2010 · Journal Article
- Folic acid enhances early functional recovery in a piglet model of pediatric head injury. — PubMed · 2010 · Journal Article
- Nanowired-drug delivery enhances neuroprotective efficacy of compounds and reduces spinal cord edema formation and improves functional outcome following spinal cord injury in the rat. — PubMed · 2010 · Journal Article
- Neuroprotection by acetyl-L-carnitine after traumatic injury to the immature rat brain. — PubMed · 2010 · Journal Article
- Neuroprotective effects of alpha-lipoic acid in experimental spinal cord injury in rats. — PubMed · 2010 · Journal Article
- Passive immunization with LINGO-1 polyclonal antiserum afforded neuroprotection and promoted functional recovery in a rat model of spinal cord injury. — PubMed · 2010 · Journal Article
- Selected combination of neurotrophins potentiate neuroprotection and functional recovery following spinal cord injury in the rat. — PubMed · 2010 · Journal Article
- The biochemical effectiveness of N-acetylcysteine in experimental spinal cord injury in rats. — PubMed · 2010 · Journal Article
- The functional and neuroprotective actions of Neu2000, a dual-acting pharmacological agent, in the treatment of acute spinal cord injury. — PubMed · 2010 · Journal Article
- Estrogen partially down-regulates PTEN to prevent apoptosis in VSC4.1 motoneurons following exposure to IFN-gamma. — PubMed · 2009 · Journal Article
- FTY720 reduces inflammation and promotes functional recovery after spinal cord injury. — PubMed · 2009 · Journal Article
- Neuroprotection against spinal cord ischemia-reperfusion injury induced by different ischemic postconditioning methods: roles of phosphatidylinositol 3-kinase-Akt and extracellular signal-regulated kinase. — PubMed · 2009 · Journal Article
- Selective cerebral perfusion at 28 degrees C--is the spinal cord safe? — PubMed · 2009 · Journal Article
- Neuroprotective effects of bone morphogenetic protein 7 (BMP7) treatment after spinal cord injury. — PubMed · 2009 · Journal Article
- Effects of rolipram on adult rat oligodendrocytes and functional recovery after contusive cervical spinal cord injury. — PubMed · 2009 · Journal Article
- Activation of p-38alpha MAPK contributes to neuronal hyperexcitability in caudal regions remote from spinal cord injury. — PubMed · 2009 · Journal Article
- Timing and duration of anti-alpha4beta1 integrin treatment after spinal cord injury: effect on therapeutic efficacy. — PubMed · 2009 · Journal Article
- Olfactory bulb implantation and methylprednisolone administration in the treatment of spinal cord injury in rats. — PubMed · 2009 · Journal Article
- A remotely controlled model of spinal cord compression injury in mice: toward real-time analysis. — PubMed · 2009 · Journal Article
- Dantrolene can reduce secondary damage after spinal cord injury. — PubMed · 2009 · Journal Article
- Deleterious versus neuroprotective effect of metabolic inhibition after traumatic spinal cord injury. — PubMed · 2009 · Journal Article
- Enhanced regenerative axon growth of multiple fibre populations in traumatic spinal cord injury following scar-suppressing treatment. — PubMed · 2009 · Journal Article
- Be careful what you train for. — PubMed · 2009 · Comment
- Chondroitinase ABC treatment opens a window of opportunity for task-specific rehabilitation. — PubMed · 2009 · Journal Article
- Effect of cyclosporin A on functional recovery in the spinal cord following contusion injury. — PubMed · 2009 · Journal Article
- Effects of long-term FK506 administration on functional and histopathological outcome after spinal cord injury in adult rat. — PubMed · 2009 · Journal Article
- Transcriptional activation of endothelial cells by TGFβ coincides with acute microvascular plasticity following focal spinal cord ischaemia/reperfusion injury. — PubMed · 2009 · Comparative Study
- Arachidonyl trifluoromethyl ketone is neuroprotective after spinal cord injury. — PubMed · 2009 · Journal Article
- Magnesium chloride in a polyethylene glycol formulation as a neuroprotective therapy for acute spinal cord injury: preclinical refinement and optimization. — PubMed · 2009 · Journal Article
- Neuroprotective effect of Scutellaria baicalensis on spinal cord injury in rats. — PubMed · 2009 · Journal Article
- Protection of erythropoietin on experimental spinal cord injury by reducing the expression of thrombospondin-1 and transforming growth factor-beta. — PubMed · 2009 · Journal Article
- Selective inhibition of hypoxia-inducible factor (HIF) prolyl-hydroxylase 1 mediates neuroprotection against normoxic oxidative death via HIF- and CREB-independent pathways. — PubMed · 2009 · Comparative Study
- Remote astrocytic and microglial activation modulates neuronal hyperexcitability and below-level neuropathic pain after spinal injury in rat. — PubMed · 2009 · Journal Article
- Brain protection by methylprednisolone in rats with spinal cord injury. — PubMed · 2009 · Journal Article
- Hypertonic saline attenuates cord swelling and edema in experimental spinal cord injury: a study utilizing magnetic resonance imaging. — PubMed · 2009 · Journal Article
- Reduced vascular endothelial growth factor expression in contusive spinal cord injury. — PubMed · 2009 · Journal Article
- Spinal NMDA receptor activation is necessary for de novo, but not the maintenance of, A2a receptor-mediated phrenic motor facilitation. — PubMed · 2009 · Journal Article
- Swim training initiated acutely after spinal cord injury is ineffective and induces extravasation in and around the epicenter. — PubMed · 2009 · Journal Article
- Modafinil normalized hyperreflexia after spinal transection in adult rats. — PubMed · 2009 · Journal Article
- Protective effect of sivelestat sodium hydrate (ONO-5046) on ischemic spinal cord injury. — PubMed · 2009 · Journal Article
- Tempol protection of spinal cord mitochondria from peroxynitrite-induced oxidative damage. — PubMed · 2009 · Journal Article
- Effectiveness of riluzole in suppressing spasticity in the spinal cord injured rat. — PubMed · 2009 · Journal Article
Where this was looked for, and when
The latest collection walk and the accumulated shelf have different scopes. A zero applies only to that source query and its date window; older records may remain on the shelf. It does not mean no research exists.
| ClinicalTrials.gov | latest collection walk returned no records | asked on 2026-10-05 Collection window: 2026-09-16 – 2026-10-05 | matched in this collection walk 0 · accumulated records across collection walks 6 · still to fetch in this walk 0 | aim: every record matching this question |
|---|---|---|---|---|
| Crossref | asked, and it answered | asked on 2026-09-16 Collection window: all dates before the end date – 2026-09-16 | matched in this collection walk 1230843 · accumulated records across collection walks 50 | aim: a sample of the most relevant records. This source ranks a bag of words, so its own total is the size of the corpus that shares some of them, never a set still owed. |
| PubMed | asked, and it answered | asked on 2026-09-17 Collection window: all dates before the end date – 2026-09-17 | matched in this collection walk 3744 · accumulated records across collection walks 3744 · still to fetch in this walk 0 | aim: every record matching this question |
The question asked
- ClinicalTrials.gov
("neuroprotection" OR "secondary injury") - Crossref
spinal cord injury neuroprotection secondary injury - PubMed
("Spinal Cord Injuries"[MeSH Terms] OR "spinal cord injury"[Title/Abstract] OR "spinal cord injuries"[Title/Abstract] OR "spinal cord trauma"[Title/Abstract]) AND ("Neuroprotection"[MeSH Terms] OR "Neuroprotective Agents"[MeSH Terms] OR "neuroprotection"[Title/Abstract] OR "secondary injury"[Title/Abstract])