A subject this map covers
Neuroprotection
What belongs here
Attempts to stop the second, delayed wave of damage in the first hours and days.
What does not belong here, however close it looks
Restoring function lost months earlier is repair, not neuroprotection.
What has been looked at
Counted from what the sources catalogue, not from reading the work. It says how much exists and over what span of years — never what any of it found.
- Registered or indexed as work in people: 1169 records · 1978–2027
- Indexed as work in animals: 1885 records · 1977–2026
- Indexed as laboratory work: 80 records · 1996–2026
- The source has not said who or what was studied: 572 records · 1991–2026
- No matching published catalogue records are linked above. Human-review status must be checked on the evidence itself.
Published in this map
Catalogue records matching this subject. Publication here does not establish human review, measured results or effectiveness. Open a record to inspect its sources and evidence.
No published catalogue records match this subject yet.
This is a result within this map, not a claim that no research exists. The source records below can help you continue searching.
Found in the scientific sources, not yet checked
Titles and identifiers as the sources publish them. Nobody here has read these papers, and nothing on this shelf is a result, a recommendation or evidence that anything works. Each line opens the original.
3706 records
This grouping is the source's own cataloguing, not a reading of the paper. It says where a record was filed, not what it found.
Indexed as work in animals
- Propentofylline-induced astrocyte modulation leads to alterations in glial glutamate promoter activation following spinal nerve transection. — PubMed · 2008 · Journal Article
- In vitro evaluation of the effect of trans-10, cis-12 conjugated linoleic acid on phagocytosis by canine peripheral blood polymorphonuclear neutrophilic leukocytes exposed to methylprednisolone sodium succinate. — PubMed · 2008 · Journal Article
- Methylprednisolone protects oligodendrocytes but not neurons after spinal cord injury. — PubMed · 2008 · Journal Article
- Limited minocycline neuroprotection after balloon-compression spinal cord injury in the rat. — PubMed · 2008 · Journal Article
- Blocking LINGO-1 function promotes retinal ganglion cell survival following ocular hypertension and optic nerve transection. — PubMed · 2008 · Journal Article
- Griffonia simplicifolia isolectin B4 identifies a specific subpopulation of angiogenic blood vessels following contusive spinal cord injury in the adult mouse. — PubMed · 2008 · Journal Article
- Neuroprotective effects of ketorolac tromethamine after spinal cord injury in rats: an ultrastructural study. — PubMed · 2008 · Journal Article
- Salvianolic acid B promotes survival of transplanted mesenchymal stem cells in spinal cord-injured rats. — PubMed · 2008 · Journal Article
- Single exposure to erythropoietin modulates Nerve Growth Factor expression in the spinal cord following traumatic injury: comparison with methylprednisolone. — PubMed · 2008 · Comparative Study
- Duration of lipid peroxidation after acute spinal cord injury in rats and the effect of methylprednisolone. — PubMed · 2008 · Journal Article
- [Effect of propofol aortic infusion on ischemia-reperfusion spinal cords of rabbits]. — PubMed · 2008 · English Abstract
- How DMSO, a widely used solvent, affects spinal cord injury. — PubMed · 2008 · Journal Article
- Immunocytochemical characterization of astrocytosis along the spinal cord of loop-tail/curly-tail mice with myelomeningocele. — PubMed · 2008 · Journal Article
- Selenium attenuates ROS-mediated apoptotic cell death of injured spinal cord through prevention of mitochondria dysfunction; in vitro and in vivo study. — PubMed · 2008 · Journal Article
- A select combination of neurotrophins enhances neuroprotection and functional recovery following spinal cord injury. — PubMed · 2007 · Journal Article
- Direct evidence for calpain involvement in apoptotic death of neurons in spinal cord injury in rats and neuroprotection with calpain inhibitor. — PubMed · 2007 · Journal Article
- Drug delivery to the spinal cord tagged with nanowire enhances neuroprotective efficacy and functional recovery following trauma to the rat spinal cord. — PubMed · 2007 · Journal Article
- A combination of intravenous and dietary docosahexaenoic acid significantly improves outcome after spinal cord injury. — PubMed · 2007 · Comparative Study
- Cell cycle activation contributes to post-mitotic cell death and secondary damage after spinal cord injury. — PubMed · 2007 · Journal Article
- Differential astroglial responses in the spinal cord of rats submitted to a sciatic nerve double crush treated with local injection of cultured Schwann cell suspension or lesioned spinal cord extract: implications on cell therapy for nerve repair. — PubMed · 2007 · Journal Article
- Post-treatment with the cyclosporin derivative, NIM811, reduced indices of cell death and increased the volume of spared tissue in the acute period following spinal cord contusion. — PubMed · 2007 · Journal Article
- Caspase-3 activity is reduced after spinal cord injury in mice lacking dynorphin: differential effects on glia and neurons. — PubMed · 2007 · Journal Article
- Effects of combination of melatonin and dexamethasone on secondary injury in an experimental mice model of spinal cord trauma. — PubMed · 2007 · Journal Article
- Erythropoietin attenuates neuronal injury and potentiates the expression of pCREB in anterior horn after transient spinal cord ischemia in rats. — PubMed · 2007 · Journal Article
- [Experimental study on effect of Suifukang in promoting repairing and regeneration of nerve fibers in spinal cord]. — PubMed · 2007 · English Abstract
- Comparative neuroprotective effect of sodium channel blockers after experimental spinal cord injury. — PubMed · 2007 · Comparative Study
- Erythropoietin and carbamylated erythropoietin are neuroprotective following spinal cord hemisection in the rat. — PubMed · 2007 · Journal Article
- Intravenous infusion of dihydroginsenoside Rb1 prevents compressive spinal cord injury and ischemic brain damage through upregulation of VEGF and Bcl-XL. — PubMed · 2007 · Journal Article
- Temporal characterization of mitochondrial bioenergetics after spinal cord injury. — PubMed · 2007 · Journal Article
- Cyclosporin-A enhances non-functional axonal growing after complete spinal cord transection. — PubMed · 2007 · Journal Article
- Effects of polyethylene glycol and magnesium sulfate administration on clinically relevant neurological outcomes after spinal cord injury in the rat. — PubMed · 2007 · Journal Article
- Serum albumin improves recovery from spinal cord injury. — PubMed · 2007 · Journal Article
- Dorsal column sensory axons lack TrkC and are not rescued by local neurotrophin-3 infusions following spinal cord contusion in adult rats. — PubMed · 2007 · Journal Article
- GM-CSF inhibits apoptosis of neural cells via regulating the expression of apoptosis-related proteins. — PubMed · 2007 · Journal Article
- Trauma with neurologic sequelae. — PubMed · 2007 · Journal Article
- Effects of magnesium sulphate following spinal cord injury in rats. — PubMed · 2007 · Comparative Study
- Central nervous system and non-central nervous system antigen vaccines exacerbate neuropathology caused by nerve injury. — PubMed · 2007 · Journal Article
- [Efficiency of coenzyme Q(10) at experimental spinal cord injury]. — PubMed · 2007 · English Abstract
- Post-trauma Lipitor treatment prevents endothelial dysfunction, facilitates neuroprotection, and promotes locomotor recovery following spinal cord injury. — PubMed · 2007 · Journal Article
- Protective effect of intrathecal ketorolac in spinal cord ischemia in rats: a microdialysis study. — PubMed · 2007 · Journal Article
- Protective action of snake venom Naja naja oxiana at spinal cord hemisection. — PubMed · 2007 · Journal Article
- Thiazolidinedione class of peroxisome proliferator-activated receptor gamma agonists prevents neuronal damage, motor dysfunction, myelin loss, neuropathic pain, and inflammation after spinal cord injury in adult rats. — PubMed · 2007 · Journal Article
- Erythropoietin-mediated preservation of the white matter in rat spinal cord injury. — PubMed · 2007 · Journal Article
- ERK 1/2 signaling pathway is involved in nicotine-mediated neuroprotection in spinal cord neurons. — PubMed · 2007 · Journal Article
- Functional neuroprotective effect of CGS 26303, a dual ECE inhibitor, on ischemic-reperfusion spinal cord injury in rats. — PubMed · 2007 · Journal Article
- Metoprolol treatment decreases tissue myeloperoxidase activity after spinal cord injury in rats. — PubMed · 2007 · Comparative Study
- Delayed riluzole treatment is able to rescue injured rat spinal motoneurons. — PubMed · 2007 · Journal Article
- Bone marrow stromal cells mediate protection through stimulation of PI3-K/Akt and MAPK signaling in neurons. — PubMed · 2007 · Journal Article
- Gene transfer of insulin-like growth factor-I providing neuroprotection after spinal cord injury in rats. — PubMed · 2007 · Evaluation Study
- Indorenate improves motor function in rats with chronic spinal cord injury. — PubMed · 2007 · Journal Article
- MK-801 upregulates NR2A protein levels and induces functional recovery of the ipsilateral hemidiaphragm following acute C2 hemisection in adult rats. — PubMed · 2007 · Journal Article
- Rat models of traumatic spinal cord injury to assess motor recovery. — PubMed · 2007 · Journal Article
- Schwann cell transplantation improves reticulospinal axon growth and forelimb strength after severe cervical spinal cord contusion. — PubMed · 2007 · Journal Article
- Mn (III) tetrakis (4-benzoic acid) porphyrin administered into the intrathecal space reduces oxidative damage and neuron death after spinal cord injury: a comparison with methylprednisolone. — PubMed · 2006 · Comparative Study
- Riluzole promotes cell survival and neurite outgrowth in rat sensory neurones in vitro. — PubMed · 2006 · Journal Article
- Isoflurane produces delayed preconditioning against spinal cord ischemic injury via release of free radicals in rabbits. — PubMed · 2006 · Journal Article
- Early administration of methylprednisolone decreases apoptotic cell death after spinal cord injury. — PubMed · 2006 · Journal Article
- Effects of resveratrol and methylprednisolone on biochemical, neurobehavioral and histopathological recovery after experimental spinal cord injury. — PubMed · 2006 · Journal Article
- The effect of glutamine on locomotor performance and skeletal muscle myosins following spinal cord injury in rats. — PubMed · 2006 · Journal Article
- The effects of systemically administered methylprednisolone and recombinant human erythropoietin after acute spinal cord compressive injury in rats. — PubMed · 2006 · Journal Article
Where this was looked for, and when
The latest collection walk and the accumulated shelf have different scopes. A zero applies only to that source query and its date window; older records may remain on the shelf. It does not mean no research exists.
| ClinicalTrials.gov | latest collection walk returned no records | asked on 2026-10-05 Collection window: 2026-09-16 – 2026-10-05 | matched in this collection walk 0 · accumulated records across collection walks 6 · still to fetch in this walk 0 | aim: every record matching this question |
|---|---|---|---|---|
| Crossref | asked, and it answered | asked on 2026-09-16 Collection window: all dates before the end date – 2026-09-16 | matched in this collection walk 1230843 · accumulated records across collection walks 50 | aim: a sample of the most relevant records. This source ranks a bag of words, so its own total is the size of the corpus that shares some of them, never a set still owed. |
| PubMed | asked, and it answered | asked on 2026-09-17 Collection window: all dates before the end date – 2026-09-17 | matched in this collection walk 3744 · accumulated records across collection walks 3744 · still to fetch in this walk 0 | aim: every record matching this question |
The question asked
- ClinicalTrials.gov
("neuroprotection" OR "secondary injury") - Crossref
spinal cord injury neuroprotection secondary injury - PubMed
("Spinal Cord Injuries"[MeSH Terms] OR "spinal cord injury"[Title/Abstract] OR "spinal cord injuries"[Title/Abstract] OR "spinal cord trauma"[Title/Abstract]) AND ("Neuroprotection"[MeSH Terms] OR "Neuroprotective Agents"[MeSH Terms] OR "neuroprotection"[Title/Abstract] OR "secondary injury"[Title/Abstract])