A subject this map covers
Neuroprotection
What belongs here
Attempts to stop the second, delayed wave of damage in the first hours and days.
What does not belong here, however close it looks
Restoring function lost months earlier is repair, not neuroprotection.
What has been looked at
Counted from what the sources catalogue, not from reading the work. It says how much exists and over what span of years — never what any of it found.
- Registered or indexed as work in people: 1169 records · 1978–2027
- Indexed as work in animals: 1885 records · 1977–2026
- Indexed as laboratory work: 80 records · 1996–2026
- The source has not said who or what was studied: 572 records · 1991–2026
- No matching published catalogue records are linked above. Human-review status must be checked on the evidence itself.
Published in this map
Catalogue records matching this subject. Publication here does not establish human review, measured results or effectiveness. Open a record to inspect its sources and evidence.
No published catalogue records match this subject yet.
This is a result within this map, not a claim that no research exists. The source records below can help you continue searching.
Found in the scientific sources, not yet checked
Titles and identifiers as the sources publish them. Nobody here has read these papers, and nothing on this shelf is a result, a recommendation or evidence that anything works. Each line opens the original.
3706 records
This grouping is the source's own cataloguing, not a reading of the paper. It says where a record was filed, not what it found.
Indexed as work in animals
- Intrathecal bupivacaine protects against extension of lesions in an acute contusive spinal cord injury model. — PubMed · 2006 · Journal Article
- Functional reinnervation of the rat lower urinary tract after cauda equina injury and repair. — PubMed · 2006 · Journal Article
- Estrogen reduces the severity of autonomic dysfunction in spinal cord-injured male mice. — PubMed · 2006 · Comparative Study
- Secondary degeneration reduced by inosine after spinal cord injury in rats. — PubMed · 2006 · Journal Article
- Potential neuroprotective effect of low dose whole-body gamma-irradiation against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced dopaminergic toxicity in C57 mice. — PubMed · 2006 · Journal Article
- 17beta-estradiol is protective in spinal cord injury in post- and pre-menopausal rats. — PubMed · 2006 · Journal Article
- Dural repair reduces connective tissue scar invasion and cystic cavity formation after acute spinal cord laceration injury in adult rats. — PubMed · 2006 · Journal Article
- Evaluation of the neuroprotective effects of citicoline after experimental spinal cord injury: improved behavioral and neuroanatomical recovery. — PubMed · 2006 · Journal Article
- Minocycline neuroprotects, reduces microgliosis, and inhibits caspase protease expression early after spinal cord injury. — PubMed · 2006 · Journal Article
- Neuroprotection and enhanced recovery with hypericum perforatum extract after experimental spinal cord injury in mice. — PubMed · 2006 · Journal Article
- Neuroprotective effect of etomidate on functional recovery in experimental spinal cord injury. — PubMed · 2006 · Comparative Study
- The effects of cyclosporin A and insulin on ischemic spinal cord injury in rabbits. — PubMed · 2006 · Journal Article
- Effects of COX-2 and iNOS inhibitors alone or in combination with olfactory ensheathing cell grafts after spinal cord injury. — PubMed · 2006 · Journal Article
- Intra-aortic injection of propofol prevents spinal cord injury during aortic surgery. — PubMed · 2006 · Journal Article
- Investigation of the dose-dependent neuroprotective effects of agmatine in experimental spinal cord injury: a prospective randomized and placebo-control trial. — PubMed · 2006 · Comparative Study
- Omega-3 fatty acids improve recovery, whereas omega-6 fatty acids worsen outcome, after spinal cord injury in the adult rat. — PubMed · 2006 · Comparative Study
- Amelioration of spinal cord compressive injury by pharmacological preconditioning with erythropoietin and a nonerythropoietic erythropoietin derivative. — PubMed · 2006 · Comparative Study
- A novel role of phospholipase A2 in mediating spinal cord secondary injury. — PubMed · 2006 · Comparative Study
- Decoy peptides that bind dynorphin noncovalently prevent NMDA receptor-mediated neurotoxicity. — PubMed · 2006 · Comparative Study
- Neuroprotective effects of melanocortins in experimental spinal cord injury. An experimental study in the rat using topical application of compounds with varying affinity to melanocortin receptors. — PubMed · 2006 · Journal Article
- Spinal cord injury induced heat shock protein expression is reduced by an antioxidant compound H-290/51. An experimental study using light and electron microscopy in the rat. — PubMed · 2006 · Journal Article
- Expression of two temporally distinct microglia-related gene clusters after spinal cord injury. — PubMed · 2006 · Journal Article
- Gender-related differences in recovery of locomotor function after spinal cord injury in mice. — PubMed · 2006 · Comparative Study
- Neuroprotective effects of Nigella sativa on experimental spinal cord injury in rats. — PubMed · 2006 · Journal Article
- Spinal cord injury-induced expression of the immune-regulatory chemokine interleukin-16 caused by activated microglia/macrophages and CD8+ cells. — PubMed · 2006 · Journal Article
- Upregulation of type I interleukin-1 receptor after traumatic spinal cord injury in adult rats. — PubMed · 2006 · Journal Article
- Changes in response to spinal cord injury with development: vascularization, hemorrhage and apoptosis. — PubMed · 2006 · Journal Article
- Effect of dimephosphon on functional recovery of damaged spinal cord. — PubMed · 2006 · Journal Article
- Matrix metalloproteinase-9 activity in the cerebrospinal fluid and serum of dogs with acute spinal cord trauma from intervertebral disk disease. — PubMed · 2006 · Journal Article
- Progesterone increases the expression of myelin basic protein and the number of cells showing NG2 immunostaining in the lesioned spinal cord. — PubMed · 2006 · Journal Article
- Total cell associated electrolyte homeostasis in rat spinal cord cells following apparently irreversible injury. — PubMed · 2006 · Journal Article
- Acute implantation of an avulsed lumbosacral ventral root into the rat conus medullaris promotes neuroprotection and graft reinnervation by autonomic and motor neurons. — PubMed · 2006 · Journal Article
- Neuroprotective effect of a new taurinamide derivative--Taurepar. — PubMed · 2006 · Evaluation Study
- Post-injury treatment with a new antioxidant compound H-290/51 attenuates spinal cord trauma-induced c-fos expression, motor dysfunction, edema formation, and cell injury in the rat. — PubMed · 2006 · Journal Article
- Post-traumatic application of brain-derived neurotrophic factor and glia-derived neurotrophic factor on the rat spinal cord enhances neuroprotection and improves motor function. — PubMed · 2006 · Journal Article
- Progesterone treatment of spinal cord injury: Effects on receptors, neurotrophins, and myelination. — PubMed · 2006 · Journal Article
- Topical application of dynorphin A (1-17) antibodies attenuates neuronal nitric oxide synthase up-regulation, edema formation, and cell injury following focal trauma to the rat spinal cord. — PubMed · 2006 · Journal Article
- Methylprednisolone neutralizes the beneficial effects of erythropoietin in experimental spinal cord injury. — PubMed · 2005 · Journal Article
- Application of magnetic resonance diffusion anisotropy imaging for the assessment neuroprotecting effects of MPEP, a selective mGluR5 antagonist, on the rat spinal cord injury in vivo. — PubMed · 2005 · Journal Article
- Post-conditioning with lipopolysaccharide reduces the inflammatory infiltrate to the injured brain and spinal cord: a potential neuroprotective treatment. — PubMed · 2005 · Journal Article
- The effects of L-arginine on neurological function, histopathology, and expression of hypoxia-inducible factor-1 alpha following spinal cord ischemia in rats. — PubMed · 2005 · Journal Article
- [The neuroprotector effect of a new taurine derivative on a model of compression spinal cord trauma in rats]. — PubMed · 2005 · Comparative Study
- Estrogen attenuated markers of inflammation and decreased lesion volume in acute spinal cord injury in rats. — PubMed · 2005 · Journal Article
- Neuroprotective effect of exogenous vascular endothelial growth factor on rat spinal cord neurons in vitro hypoxia. — PubMed · 2005 · Journal Article
- Dose-dependent neuroprotective effects of melatonin on experimental spinal cord injury in rats. — PubMed · 2005 · Comparative Study
- Neuroimmunophilin ligands improve functional recovery and increase axonal growth after spinal cord hemisection in rats. — PubMed · 2005 · Journal Article
- Protective use of N-methyl-D-aspartate receptor antagonists as a spinoplegia against excitatory amino acid neurotoxicity. — PubMed · 2005 · Comparative Study
- FK 506 reduces tissue damage and prevents functional deficit after spinal cord injury in the rat. — PubMed · 2005 · Journal Article
- Neuroprotective effects of novel small peptides in vitro and after brain injury. — PubMed · 2005 · Journal Article
- Geranylgeranylacetone limits secondary injury, neuronal death, and progressive necrosis and cavitation after spinal cord injury. — PubMed · 2005 · Comparative Study
- [An experimental study of the neuroprotective effect of FK506 on acute spinal cord injury in dogs]. — PubMed · 2005 · English Abstract
- Pituitary adenylate cyclase-activating polypeptide prevents cell death in the spinal cord with traumatic injury. — PubMed · 2005 · Comparative Study
- Gene expression profiling of experimental traumatic spinal cord injury as a function of distance from impact site and injury severity. — PubMed · 2005 · Journal Article
- Comparison of effects of methylprednisolone and anti-CD11d antibody treatments on autonomic dysreflexia after spinal cord injury. — PubMed · 2005 · Comparative Study
- Erythropoietin protects dopaminergic neurons and improves neurobehavioral outcomes in juvenile rats after neonatal hypoxia-ischemia. — PubMed · 2005 · Journal Article
- Neuroprotective effects of neurotrophins and melanocortins in spinal cord injury: an experimental study in the rat using pharmacological and morphological approaches. — PubMed · 2005 · Journal Article
- Neuroprotective effects of nitric oxide synthase inhibitors in spinal cord injury-induced pathophysiology and motor functions: an experimental study in the rat. — PubMed · 2005 · Journal Article
- The role of inducible nitric oxide synthase following spinal cord injury in rat. — PubMed · 2005 · Comparative Study
- [Change of gene expression pattern and regulation of SFK on the change in early stage after hemitransection of the spinal cord in rat]. — PubMed · 2005 · English Abstract
- Mexiletine treatment-induced inhibition of caspase-3 activation and improvement of behavioral recovery after spinal cord injury. — PubMed · 2005 · Comparative Study
Where this was looked for, and when
The latest collection walk and the accumulated shelf have different scopes. A zero applies only to that source query and its date window; older records may remain on the shelf. It does not mean no research exists.
| ClinicalTrials.gov | latest collection walk returned no records | asked on 2026-10-05 Collection window: 2026-09-16 – 2026-10-05 | matched in this collection walk 0 · accumulated records across collection walks 6 · still to fetch in this walk 0 | aim: every record matching this question |
|---|---|---|---|---|
| Crossref | asked, and it answered | asked on 2026-09-16 Collection window: all dates before the end date – 2026-09-16 | matched in this collection walk 1230843 · accumulated records across collection walks 50 | aim: a sample of the most relevant records. This source ranks a bag of words, so its own total is the size of the corpus that shares some of them, never a set still owed. |
| PubMed | asked, and it answered | asked on 2026-09-17 Collection window: all dates before the end date – 2026-09-17 | matched in this collection walk 3744 · accumulated records across collection walks 3744 · still to fetch in this walk 0 | aim: every record matching this question |
The question asked
- ClinicalTrials.gov
("neuroprotection" OR "secondary injury") - Crossref
spinal cord injury neuroprotection secondary injury - PubMed
("Spinal Cord Injuries"[MeSH Terms] OR "spinal cord injury"[Title/Abstract] OR "spinal cord injuries"[Title/Abstract] OR "spinal cord trauma"[Title/Abstract]) AND ("Neuroprotection"[MeSH Terms] OR "Neuroprotective Agents"[MeSH Terms] OR "neuroprotection"[Title/Abstract] OR "secondary injury"[Title/Abstract])