A subject this map covers
Neuroprotection
What belongs here
Attempts to stop the second, delayed wave of damage in the first hours and days.
What does not belong here, however close it looks
Restoring function lost months earlier is repair, not neuroprotection.
What has been looked at
Counted from what the sources catalogue, not from reading the work. It says how much exists and over what span of years — never what any of it found.
- Registered or indexed as work in people: 1169 records · 1978–2027
- Indexed as work in animals: 1885 records · 1977–2026
- Indexed as laboratory work: 80 records · 1996–2026
- The source has not said who or what was studied: 572 records · 1991–2026
- No matching published catalogue records are linked above. Human-review status must be checked on the evidence itself.
Published in this map
Catalogue records matching this subject. Publication here does not establish human review, measured results or effectiveness. Open a record to inspect its sources and evidence.
No published catalogue records match this subject yet.
This is a result within this map, not a claim that no research exists. The source records below can help you continue searching.
Found in the scientific sources, not yet checked
Titles and identifiers as the sources publish them. Nobody here has read these papers, and nothing on this shelf is a result, a recommendation or evidence that anything works. Each line opens the original.
3706 records
This grouping is the source's own cataloguing, not a reading of the paper. It says where a record was filed, not what it found.
Indexed as work in animals
- The Neuroprotection of puerarin against cerebral ischemia is associated with the prevention of apoptosis in rats. — PubMed · 2005 · Journal Article
- Embryonic radial glia bridge spinal cord lesions and promote functional recovery following spinal cord injury. — PubMed · 2005 · Comparative Study
- Neurochemical evidence for agmatine modulation of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) neurotoxicity. — PubMed · 2005 · Journal Article
- Neuroprotective effect of 1-aminocyclopropanecarboxylic acid in a rabbit spinal ischemia model. — PubMed · 2005 · Journal Article
- Secondary spinal cord hypoperfusion of circumscribed areas after injury in rats. — PubMed · 2005 · Comparative Study
- Neuroprotection and enhanced recovery with edaravone after acute spinal cord injury in rats. — PubMed · 2005 · Journal Article
- Cellular localization and enzymatic activity of cathepsin B after spinal cord injury in the rat. — PubMed · 2005 · Comparative Study
- Real-time quantitative PCR analysis of temporal-spatial alterations in gene expression after spinal cord contusion. — PubMed · 2005 · Comparative Study
- Selective caspase activation may contribute to neurological dysfunction after experimental spinal cord trauma. — PubMed · 2005 · Journal Article
- An adult rat spinal cord contusion model of sensory axon degeneration: the estrus cycle or a preconditioning lesion do not affect outcome. — PubMed · 2005 · Journal Article
- Blockade of sodium channels by phenytoin protects ultrastructure and attenuates lipid peroxidation in experimental spinal cord injury. — PubMed · 2005 · Comparative Study
- Methylprednisolone inhibits production of interleukin-1beta and interleukin-6 in the spinal cord following compression injury in rats. — PubMed · 2005 · Journal Article
- Neuroprotective action of hypothalamic peptide PRP-1 at various time survivals following spinal cord hemisection. — PubMed · 2005 · Journal Article
- Neuroprotective effect of cytoflavin during compression injury of the spinal cord. — PubMed · 2005 · Journal Article
- Early protective effects of iloprost, a stable prostacyclin analog, during spinal cord ischemia in a rabbit model. — PubMed · 2005 · Journal Article
- Effects of epidural hypothermic saline infusion on locomotor outcome and tissue preservation after moderate thoracic spinal cord contusion in rats. — PubMed · 2005 · Journal Article
- Neuroprotection and functional recovery after application of the caspase-9 inhibitor z-LEHD-fmk in a rat model of traumatic spinal cord injury. — PubMed · 2005 · Journal Article
- Neuroprotective effects of ebselen on experimental spinal cord injury in rats. — PubMed · 2005 · Journal Article
- Nicotine attenuates morphological deficits in a contusion model of spinal cord injury. — PubMed · 2005 · Journal Article
- Progesterone neuroprotection in spinal cord trauma involves up-regulation of brain-derived neurotrophic factor in motoneurons. — PubMed · 2005 · Journal Article
- MRI diffusion coefficients in spinal cord correlate with axon morphometry. — PubMed · 2005 · Journal Article
- Chronic alterations in the cellular composition of spinal cord white matter following contusion injury. — PubMed · 2005 · Journal Article
- Magnesium sulfate treatment decreases caspase-3 activity after experimental spinal cord injury in rats. — PubMed · 2005 · Comparative Study
- MK-801 improves neurological and histological outcomes after spinal cord ischemia induced by transient aortic cross-clipping in rats. — PubMed · 2005 · Journal Article
- Role of granulocyte-macrophage colony-stimulating factor in preventing apoptosis and improving functional outcome in experimental spinal cord contusion injury. — PubMed · 2005 · Journal Article
- Effect of combined treatment with melatonin and methylprednisolone on neurological recovery after experimental spinal cord injury. — PubMed · 2004 · Journal Article
- Is intrathecal magnesium sulfate safe and protective against ischemic spinal cord injury in rabbits? — PubMed · 2004 · Journal Article
- Time-level relationship for nitric oxide and the protective effects of aminoguanidine in experimental spinal cord injury. — PubMed · 2004 · Journal Article
- Plasma membrane calcium ATPase expression in the rat spinal cord. — PubMed · 2004 · Journal Article
- Correlation of injury severity and tissue Evans blue content, lipid peroxidation and clinical evaluation in acute spinal cord injury in rats. — PubMed · 2004 · Evaluation Study
- [Preliminary study of the effects of high-dose Vitamin C on acute spinal cord injury in rats]. — PubMed · 2004 · Comparative Study
- [Study on effect of suifukang in regulating the change of free radical after hemitransected spinal cord injury]. — PubMed · 2004 · English Abstract
- The protective effect of nebivolol on ischemia/reperfusion injury in rabbit spinal cord. — PubMed · 2004 · Journal Article
- Suppression of GDNF production by MPSS treatment following spinal cord injury in the rat. — PubMed · 2004 · Comparative Study
- A neuroprotective role of glial cell line-derived neurotrophic factor following moderate spinal cord contusion injury. — PubMed · 2004 · Journal Article
- Inhibition of the nuclear factor-kappaB activation with pyrrolidine dithiocarbamate attenuating inflammation and oxidative stress after experimental spinal cord trauma in rats. — PubMed · 2004 · Journal Article
- Protective effect of liposome-mediated glial cell line-derived neurotrophic factor gene transfer in vivo on motoneurons following spinal cord injury in rats. — PubMed · 2004 · Comparative Study
- Tempol, a nitroxide antioxidant, improves locomotor and histological outcomes after spinal cord contusion in rats. — PubMed · 2004 · Journal Article
- The mitochondrial uncoupling agent 2,4-dinitrophenol improves mitochondrial function, attenuates oxidative damage, and increases white matter sparing in the contused spinal cord. — PubMed · 2004 · Journal Article
- Injury in the spinal cord may produce cell death in the brain. — PubMed · 2004 · Comparative Study
- AIT-082 and methylprednisolone singly, but not in combination, enhance functional and histological improvement after acute spinal cord injury in rats. — PubMed · 2004 · Journal Article
- Higher calpastatin levels correlate with resistance to calpain-mediated proteolysis and neuronal apoptosis in juvenile rats after spinal cord injury. — PubMed · 2004 · Comparative Study
- Lesional RhoA+ cell numbers are suppressed by anti-inflammatory, cyclooxygenase-inhibiting treatment following subacute spinal cord injury. — PubMed · 2004 · Journal Article
- P2X7 receptor inhibition improves recovery after spinal cord injury. — PubMed · 2004 · Comparative Study
- Polyethylene glycol improves function and reduces oxidative stress in synaptosomal preparations following spinal cord injury. — PubMed · 2004 · Journal Article
- Sodium channel blockade with phenytoin protects spinal cord axons, enhances axonal conduction, and improves functional motor recovery after contusion SCI. — PubMed · 2004 · Journal Article
- Upregulation of annexins I, II, and V after traumatic spinal cord injury in adult rats. — PubMed · 2004 · Comparative Study
- Tissue expression of 165-aa vascular permeability factor after spinal cord injury is not influenced by dexamethasone administration in rats. — PubMed · 2004 · Journal Article
- Spontaneous and induced aberrant sprouting at the site of injury is irrelevant to motor function outcome in rats with spinal cord injury. — PubMed · 2004 · Journal Article
- Induction of HIF1alpha but not HIF2alpha in motoneurons after ventral funiculus axotomy-implication in neuronal survival strategies. — PubMed · 2004 · Journal Article
- Neuroprotective effects of recombinant thrombomodulin in controlled contusion spinal cord injury implicates thrombin signaling. — PubMed · 2004 · Journal Article
- Resveratrol, a red wine polyphenol, protects spinal cord from ischemia-reperfusion injury. — PubMed · 2004 · Journal Article
- Acrolein induces axolemmal disruption, oxidative stress, and mitochondrial impairment in spinal cord tissue. — PubMed · 2004 · Journal Article
- Concentrations of glutamate released following spinal cord injury kill oligodendrocytes in the spinal cord. — PubMed · 2004 · Journal Article
- Relatively low levels of calpain expression in juvenile rat correlate with less neuronal apoptosis after spinal cord injury. — PubMed · 2004 · Journal Article
- The therapeutic window after spinal cord injury can accommodate T cell-based vaccination and methylprednisolone in rats. — PubMed · 2004 · Comparative Study
- Comparison of methylprednisolone with dexamethasone in treatment of acute spinal injury in rats. — PubMed · 2004 · Comparative Study
- Prevention of postischemic spinal cord injury by means of regional infusion of adenosine and L-carnitine dissolved in normothermic saline. — PubMed · 2004 · Comparative Study
- Transient blockade of the CD11d/CD18 integrin reduces secondary damage after spinal cord injury, improving sensory, autonomic, and motor function. — PubMed · 2004 · Journal Article
- Dural closure, cord approximation, and clot removal: enhancement of tissue sparing in a novel laceration spinal cord injury model. — PubMed · 2004 · Journal Article
Where this was looked for, and when
The latest collection walk and the accumulated shelf have different scopes. A zero applies only to that source query and its date window; older records may remain on the shelf. It does not mean no research exists.
| ClinicalTrials.gov | latest collection walk returned no records | asked on 2026-10-05 Collection window: 2026-09-16 – 2026-10-05 | matched in this collection walk 0 · accumulated records across collection walks 6 · still to fetch in this walk 0 | aim: every record matching this question |
|---|---|---|---|---|
| Crossref | asked, and it answered | asked on 2026-09-16 Collection window: all dates before the end date – 2026-09-16 | matched in this collection walk 1230843 · accumulated records across collection walks 50 | aim: a sample of the most relevant records. This source ranks a bag of words, so its own total is the size of the corpus that shares some of them, never a set still owed. |
| PubMed | asked, and it answered | asked on 2026-09-17 Collection window: all dates before the end date – 2026-09-17 | matched in this collection walk 3744 · accumulated records across collection walks 3744 · still to fetch in this walk 0 | aim: every record matching this question |
The question asked
- ClinicalTrials.gov
("neuroprotection" OR "secondary injury") - Crossref
spinal cord injury neuroprotection secondary injury - PubMed
("Spinal Cord Injuries"[MeSH Terms] OR "spinal cord injury"[Title/Abstract] OR "spinal cord injuries"[Title/Abstract] OR "spinal cord trauma"[Title/Abstract]) AND ("Neuroprotection"[MeSH Terms] OR "Neuroprotective Agents"[MeSH Terms] OR "neuroprotection"[Title/Abstract] OR "secondary injury"[Title/Abstract])