A subject this map covers
Neuroprotection
What belongs here
Attempts to stop the second, delayed wave of damage in the first hours and days.
What does not belong here, however close it looks
Restoring function lost months earlier is repair, not neuroprotection.
What has been looked at
Counted from what the sources catalogue, not from reading the work. It says how much exists and over what span of years — never what any of it found.
- Registered or indexed as work in people: 1169 records · 1978–2027
- Indexed as work in animals: 1885 records · 1977–2026
- Indexed as laboratory work: 80 records · 1996–2026
- The source has not said who or what was studied: 572 records · 1991–2026
- No matching published catalogue records are linked above. Human-review status must be checked on the evidence itself.
Published in this map
Catalogue records matching this subject. Publication here does not establish human review, measured results or effectiveness. Open a record to inspect its sources and evidence.
No published catalogue records match this subject yet.
This is a result within this map, not a claim that no research exists. The source records below can help you continue searching.
Found in the scientific sources, not yet checked
Titles and identifiers as the sources publish them. Nobody here has read these papers, and nothing on this shelf is a result, a recommendation or evidence that anything works. Each line opens the original.
3706 records
This grouping is the source's own cataloguing, not a reading of the paper. It says where a record was filed, not what it found.
Indexed as work in animals
- Erythropoietin exerts neuroprotection after acute spinal cord injury in rats: effect on lipid peroxidation and early ultrastructural findings. — PubMed · 2004 · Comparative Study
- Intrathecal bupivacaine protects against extension of lesions in an acute photochemical spinal cord injury model. — PubMed · 2004 · Journal Article
- Double labeling serial sections to enhance three-dimensional imaging of injured spinal cord. — PubMed · 2004 · Journal Article
- Minocycline treatment reduces delayed oligodendrocyte death, attenuates axonal dieback, and improves functional outcome after spinal cord injury. — PubMed · 2004 · Journal Article
- Minocycline inhibits contusion-triggered mitochondrial cytochrome c release and mitigates functional deficits after spinal cord injury. — PubMed · 2004 · Journal Article
- Decorin suppresses neurocan, brevican, phosphacan and NG2 expression and promotes axon growth across adult rat spinal cord injuries. — PubMed · 2004 · Journal Article
- Low-dose gamma-irradiation promotes survival of injured neurons in the central nervous system via homeostasis-driven proliferation of T cells. — PubMed · 2004 · Comparative Study
- Cathepsin B mRNA and protein expression following contusion spinal cord injury in rats. — PubMed · 2004 · Journal Article
- Neuroprotective effects of nicotinamide after experimental spinal cord injury. — PubMed · 2004 · Comparative Study
- Treatment with the neurosteroid dehydroepiandrosterone promotes recovery of motor behavior after moderate contusive spinal cord injury in the mouse. — PubMed · 2004 · Journal Article
- The surfactant poloxamer-188 protects against glutamate toxicity in the rat brain. — PubMed · 2004 · Comparative Study
- Differential gene expression after complete spinal cord transection in adult rats: an analysis focused on a subchronic post-injury stage. — PubMed · 2004 · Journal Article
- Gifts from the molecular revolution: protection and repair of the injured spinal cord. — PubMed · 2004 · Lecture
- Hydroxyl radicals generated in the rat spinal cord at the level produced by impact injury induce cell death by necrosis and apoptosis: protection by a metalloporphyrin. — PubMed · 2004 · Comparative Study
- Neuroprotective effects of FK-506, L-carnitine and azathioprine on spinal cord ischemia-reperfusion injury. — PubMed · 2004 · Journal Article
- Progesterone up-regulates neuronal brain-derived neurotrophic factor expression in the injured spinal cord. — PubMed · 2004 · Journal Article
- The effects of endogenous interleukin-10 on gray matter damage and the development of pain behaviors following excitotoxic spinal cord injury in the mouse. — PubMed · 2004 · Journal Article
- Electrical stimulation of the dorsal periaqueductal gray decreases volume of the brain infarction independently of accompanying hypertension and cerebrovasodilation. — PubMed · 2003 · Comparative Study
- Cellular GDNF delivery promotes growth of motor and dorsal column sensory axons after partial and complete spinal cord transections and induces remyelination. — PubMed · 2003 · Journal Article
- Steroid effects on glial cells: detrimental or protective for spinal cord function? — PubMed · 2003 · Comparative Study
- An adverse role for matrix metalloproteinase 12 after spinal cord injury in mice. — PubMed · 2003 · Journal Article
- Delayed transplantation of fibroblasts genetically modified to secrete BDNF and NT-3 into a spinal cord injury site is associated with limited recovery of function. — PubMed · 2003 · Journal Article
- Differences in cytokine gene expression profile between acute and secondary injury in adult rat spinal cord. — PubMed · 2003 · Journal Article
- Differential gene expression profiles in embryonic, adult-injured and adult-uninjured rat spinal cords. — PubMed · 2003 · Comparative Study
- Effects of injury and progesterone treatment on progesterone receptor and progesterone binding protein 25-Dx expression in the rat spinal cord. — PubMed · 2003 · Journal Article
- Leukemia inhibitory factor promotes recovery of locomotor function following spinal cord injury in the mouse. — PubMed · 2003 · Comparative Study
- Restriction of axonal retraction and promotion of axonal regeneration by chronically injured neurons after intraspinal treatment with glial cell line-derived neurotrophic factor (GDNF). — PubMed · 2003 · Comparative Study
- Expression of the type 1 and type 2 receptors for tumor necrosis factor after traumatic spinal cord injury in adult rats. — PubMed · 2003 · Journal Article
- Magnesium sulfate treatment in experimental spinal cord injury: emphasis on vascular changes and early clinical results. — PubMed · 2003 · Journal Article
- Vaccination with dendritic cells pulsed with peptides of myelin basic protein promotes functional recovery from spinal cord injury. — PubMed · 2003 · Journal Article
- Differential temporal expression of matrix metalloproteinases after spinal cord injury: relationship to revascularization and wound healing. — PubMed · 2003 · Journal Article
- Effects of cyclosporin-A on immune response, tissue protection and motor function of rats subjected to spinal cord injury. — PubMed · 2003 · Journal Article
- Changes in glial cell white matter AMPA receptor expression after spinal cord injury and relationship to apoptotic cell death. — PubMed · 2003 · Journal Article
- Creatine diet supplement for spinal cord injury: influences on functional recovery and tissue sparing in rats. — PubMed · 2003 · Comparative Study
- Early induction of secondary injury factors causing activation of calpain and mitochondria-mediated neuronal apoptosis following spinal cord injury in rats. — PubMed · 2003 · Journal Article
- Effects of resveratrol on secondary damages after acute spinal cord injury in rats. — PubMed · 2003 · Journal Article
- Ex vivo MR determined apparent diffusion coefficients correlate with motor recovery mediated by intraspinal transplants of fibroblasts genetically modified to express BDNF. — PubMed · 2003 · Journal Article
- Role of inflammation in the secondary injury following experimental spinal cord trauma. — PubMed · 2003 · Journal Article
- Effect of magnesium sulphate in experimental spinal cord injury: evaluation with ultrastructural findings and early clinical results. — PubMed · 2003 · Journal Article
- Poly(ADP-Ribose) polymerase-1 in acute neuronal death and inflammation: a strategy for neuroprotection. — PubMed · 2003 · Journal Article
- Neuroprotective effects of GYKI 52466 on experimental spinal cord injury in rats. — PubMed · 2003 · Comparative Study
- A possible role of RhoA/Rho-kinase in experimental spinal cord injury in rat. — PubMed · 2003 · Journal Article
- Acute phase effects of ATP-MgCl2 on experimental spinal cord injury. — PubMed · 2003 · Journal Article
- A new antioxidant compound H-290151 attenuates spinal cord injury induced expression of constitutive and inducible isoforms of nitric oxide synthase and edema formation in the rat. — PubMed · 2003 · Journal Article
- Decreased neural damage after spinal cord injury in tPA-deficient mice. — PubMed · 2003 · Journal Article
- Low molecular weight compounds with affinity to melanocortin receptors exert neuroprotection in spinal cord injury--an experimental study in the rat. — PubMed · 2003 · Journal Article
- Neurotrophic factors attenuate microvascular permeability disturbances and axonal injury following trauma to the rat spinal cord. — PubMed · 2003 · Journal Article
- [Repair of the mammalian central nervous system: the "spinal cord" model]. — PubMed · 2003 · English Abstract
- Sustained spinal cord compression: part II: effect of methylprednisolone on regional blood flow and recovery of somatosensory evoked potentials. — PubMed · 2003 · Journal Article
- Sustained spinal cord compression: part I: time-dependent effect on long-term pathophysiology. — PubMed · 2003 · Journal Article
- [Protective effect of dansheng injection on experimental rabbits' spinal cord injury]. — PubMed · 2002 · English Abstract
- Basis of progesterone protection in spinal cord neurodegeneration. — PubMed · 2002 · Journal Article
- [Protective effect of adenosine receptor agonists in a model of spinal cord injury in rats]. — PubMed · 2002 · English Abstract
- Protective effects of oral creatine supplementation on spinal cord injury in rats. — PubMed · 2002 · Journal Article
- Ensheathing cells and methylprednisolone promote axonal regeneration and functional recovery in the lesioned adult rat spinal cord. — PubMed · 2002 · Journal Article
- Treatment of spinal cord impact injury in the rat with transforming growth factor-beta. — PubMed · 2002 · Comparative Study
- Adenosine A2A analogue improves neurologic outcome after spinal cord trauma in the rabbit. — PubMed · 2002 · Evaluation Study
- Effects of methylprednisolone and dextromethorphan on lipid peroxidation in an experimental model of spinal cord injury. — PubMed · 2002 · Comparative Study
- NBQX treatment improves mitochondrial function and reduces oxidative events after spinal cord injury. — PubMed · 2002 · Journal Article
- Neuroprotection of glial cell line-derived neurotrophic factor in damaged spinal cords following contusive injury. — PubMed · 2002 · Journal Article
Where this was looked for, and when
The latest collection walk and the accumulated shelf have different scopes. A zero applies only to that source query and its date window; older records may remain on the shelf. It does not mean no research exists.
| ClinicalTrials.gov | latest collection walk returned no records | asked on 2026-10-05 Collection window: 2026-09-16 – 2026-10-05 | matched in this collection walk 0 · accumulated records across collection walks 6 · still to fetch in this walk 0 | aim: every record matching this question |
|---|---|---|---|---|
| Crossref | asked, and it answered | asked on 2026-09-16 Collection window: all dates before the end date – 2026-09-16 | matched in this collection walk 1230843 · accumulated records across collection walks 50 | aim: a sample of the most relevant records. This source ranks a bag of words, so its own total is the size of the corpus that shares some of them, never a set still owed. |
| PubMed | asked, and it answered | asked on 2026-09-17 Collection window: all dates before the end date – 2026-09-17 | matched in this collection walk 3744 · accumulated records across collection walks 3744 · still to fetch in this walk 0 | aim: every record matching this question |
The question asked
- ClinicalTrials.gov
("neuroprotection" OR "secondary injury") - Crossref
spinal cord injury neuroprotection secondary injury - PubMed
("Spinal Cord Injuries"[MeSH Terms] OR "spinal cord injury"[Title/Abstract] OR "spinal cord injuries"[Title/Abstract] OR "spinal cord trauma"[Title/Abstract]) AND ("Neuroprotection"[MeSH Terms] OR "Neuroprotective Agents"[MeSH Terms] OR "neuroprotection"[Title/Abstract] OR "secondary injury"[Title/Abstract])