A subject this map covers
Neuroprotection
What belongs here
Attempts to stop the second, delayed wave of damage in the first hours and days.
What does not belong here, however close it looks
Restoring function lost months earlier is repair, not neuroprotection.
What has been looked at
Counted from what the sources catalogue, not from reading the work. It says how much exists and over what span of years — never what any of it found.
- Registered or indexed as work in people: 1169 records · 1978–2027
- Indexed as work in animals: 1885 records · 1977–2026
- Indexed as laboratory work: 80 records · 1996–2026
- The source has not said who or what was studied: 572 records · 1991–2026
- No matching published catalogue records are linked above. Human-review status must be checked on the evidence itself.
Published in this map
Catalogue records matching this subject. Publication here does not establish human review, measured results or effectiveness. Open a record to inspect its sources and evidence.
No published catalogue records match this subject yet.
This is a result within this map, not a claim that no research exists. The source records below can help you continue searching.
Found in the scientific sources, not yet checked
Titles and identifiers as the sources publish them. Nobody here has read these papers, and nothing on this shelf is a result, a recommendation or evidence that anything works. Each line opens the original.
3706 records
This grouping is the source's own cataloguing, not a reading of the paper. It says where a record was filed, not what it found.
Indexed as work in animals
- Ultrastructural scoring of graded acute spinal cord injury in the rat. — PubMed · 2002 · Journal Article
- The effects of topical L-arginine and Ng-nitro-L-arginine methyl ester after experimental acute spinal cord injury. A light and electron microscopic study. — PubMed · 2002 · Comparative Study
- DNA microarray analysis of the contused spinal cord: effect of NMDA receptor inhibition. — PubMed · 2002 · Journal Article
- 9-Carboxymethyl-5H,10H-imidazo[1,2-a]indeno[1,2-e]pyrazin-4-one-2-carbocylic acid (RPR117824): selective anticonvulsive and neuroprotective AMPA antagonist. — PubMed · 2002 · Journal Article
- Effect of bilateral hypogastric nerve transection on voiding dysfunction in rats with spinal cord injury. — PubMed · 2002 · Journal Article
- Methylprednisolone and interleukin-10 reduce gray matter damage in the contused Fischer rat thoracic spinal cord but do not improve functional outcome. — PubMed · 2002 · Journal Article
- Neurotrophins reduce degeneration of injured ascending sensory and corticospinal motor axons in adult rat spinal cord. — PubMed · 2002 · Journal Article
- Re-evaluation of phencyclidine low-affinity or "non-NMDA" binding sites. — PubMed · 2002 · Journal Article
- Efficacy of methylprednisolone therapy for the injured rat spinal cord. — PubMed · 2002 · Journal Article
- Pathological CNS autoimmune disease triggered by traumatic spinal cord injury: implications for autoimmune vaccine therapy. — PubMed · 2002 · Journal Article
- Functional recovery following traumatic spinal cord injury mediated by a unique polymer scaffold seeded with neural stem cells. — PubMed · 2002 · Journal Article
- Cellular basis for progesterone neuroprotection in the injured spinal cord. — PubMed · 2002 · Evaluation Study
- Neuroprotective effects of ginseng total saponin and ginsenosides Rb1 and Rg1 on spinal cord neurons in vitro. — PubMed · 2002 · Journal Article
- A new antioxidant compound H-290/51 modulates glutamate and GABA immunoreactivity in the rat spinal cord following trauma. — PubMed · 2002 · Journal Article
- Assessment of spinal cord pathology following trauma using early changes in the spinal cord evoked potentials: a pharmacological and morphological study in the rat. — PubMed · 2002 · Journal Article
- Cell death in models of spinal cord injury. — PubMed · 2002 · Journal Article
- Group I metabotropic glutamate receptors in spinal cord injury: roles in neuroprotection and the development of chronic central pain. — PubMed · 2002 · Journal Article
- Locomotor recovery in chronic spinal rat: long-term pharmacological treatment or transplantation of embryonic neurons? — PubMed · 2002 · Journal Article
- Repeated topical application of growth hormone attenuates blood-spinal cord barrier permeability and edema formation following spinal cord injury: an experimental study in the rat using Evans blue, ([125])I-sodium and lanthanum tracers. — PubMed · 2002 · Journal Article
- Transplants and neurotrophic factors increase regeneration and recovery of function after spinal cord injury. — PubMed · 2002 · Journal Article
- GeneChip analysis after acute spinal cord injury in rat. — PubMed · 2001 · Journal Article
- Reduction of ischemic spinal cord injury by dextrorphan: comparison of several methods of administration. — PubMed · 2001 · Comparative Study
- Regional and temporal changes in prostaglandin E2 and thromboxane B2 concentrations after spinal cord injury. — PubMed · 2001 · Journal Article
- Inhibition of calpain-mediated apoptosis by E-64 d-reduced immediate early gene (IEG) expression and reactive astrogliosis in the lesion and penumbra following spinal cord injury in rats. — PubMed · 2001 · Journal Article
- Time course studies on the effectiveness of tetrodotoxin in reducing consequences of spinal cord contusion. — PubMed · 2001 · Journal Article
- Glucocorticoid effects on Fos immunoreactivity and NADPH-diaphorase histochemical staining following spinal cord injury. — PubMed · 2001 · Journal Article
- Posttraumatic therapeutic vaccination with modified myelin self-antigen prevents complete paralysis while avoiding autoimmune disease. — PubMed · 2001 · Journal Article
- Tumor necrosis factor-alpha induces cFOS and strongly potentiates glutamate-mediated cell death in the rat spinal cord. — PubMed · 2001 · Journal Article
- Detrimental effects of systemic hyperthermia on locomotor function and histopathological outcome after traumatic spinal cord injury in the rat. — PubMed · 2001 · Journal Article
- Effect of anti-rat interleukin-6 antibody after spinal cord injury in the rat: inducible nitric oxide synthase expression, sodium- and potassium-activated, magnesium-dependent adenosine-5'-triphosphatase and superoxide dismutase activation, and ultrastructural changes. — PubMed · 2001 · Journal Article
- Neuroprotective effect of regional carnitine on spinal cord ischemia--reperfusion injury. — PubMed · 2001 · Journal Article
- Chemokine antagonist infusion promotes axonal sparing after spinal cord contusion injury in rat. — PubMed · 2001 · Journal Article
- Cell death in spinal cord injury (SCI) requires de novo protein synthesis. Calpain inhibitor E-64-d provides neuroprotection in SCI lesion and penumbra. — PubMed · 2001 · Journal Article
- Cellular localization of tumor necrosis factor-alpha following acute spinal cord injury in adult rats. — PubMed · 2001 · Journal Article
- iNOS and nitrotyrosine expression after spinal cord injury. — PubMed · 2001 · Journal Article
- Prostaglandin release by spinal cord injury mediates production of hydroxyl radical, malondialdehyde and cell death: a site of the neuroprotective action of methylprednisolone. — PubMed · 2001 · Journal Article
- The effects of FK506 on neurologic and histopathologic outcome after transient spinal cord ischemia induced by aortic cross-clamping in rats. — PubMed · 2001 · Journal Article
- Delayed glial cell death following wallerian degeneration in white matter tracts after spinal cord dorsal column cordotomy in adult rats. — PubMed · 2001 · Journal Article
- Evaluation of the neuroprotective effects of sodium channel blockers after spinal cord injury: improved behavioral and neuroanatomical recovery with riluzole. — PubMed · 2001 · Journal Article
- Temporal-spatial pattern of acute neuronal and glial loss after spinal cord contusion. — PubMed · 2001 · Journal Article
- Protein and DNA oxidation in spinal injury: neurofilaments--an oxidation target. — PubMed · 2001 · Journal Article
- Spinal taurine levels are increased 7 and 30 days following methylprednisolone treatment of spinal cord injury in rats. — PubMed · 2001 · Journal Article
- [Effect of fetal spinal cord graft with nerve growth factor and nimodipine in secondary injury of spinal cord of adult rat]. — PubMed · 2001 · English Abstract
- Effects of enriched housing on functional recovery after spinal cord contusive injury in the adult rat. — PubMed · 2001 · Journal Article
- Distribution of gacyclidine enantiomers after experimental spinal cord injury in rats: possible involvement of an active transport system. — PubMed · 2001 · Journal Article
- Effects of intrathecal morphine, baclofen, clonidine and R-PIA on the acute allodynia-like behaviours after spinal cord ischaemia in rats. — PubMed · 2001 · Comparative Study
- Glucocorticoid receptor-mediated suppression of activator protein-1 activation and matrix metalloproteinase expression after spinal cord injury. — PubMed · 2001 · Journal Article
- Intraspinal implants of fibrin glue containing glial cell line-derived neurotrophic factor promote dorsal root regeneration into spinal cord. — PubMed · 2001 · Journal Article
- Tonicity of resuscitative fluids influences outcome after spinal cord injury. — PubMed · 2001 · Journal Article
- BDNF abolishes the survival effect of NT-3 in axotomized Clarke neurons of adult rats. — PubMed · 2000 · Journal Article
- Accelerated functional recovery and neuroprotection by agmatine after spinal cord ischemia in rats. — PubMed · 2000 · Journal Article
- Adenovirus-mediated glial cell line-derived neurotrophic factor gene delivery reduces motor neuron injury after transient spinal cord ischemia in rabbits. — PubMed · 2000 · Journal Article
- Comparison of the protection against neuronal injury by hypothalamic peptides and by dexamethasone. — PubMed · 2000 · Comparative Study
- Effect of brain-derived neurotrophic factor, nerve growth factor, and neurotrophin-3 on functional recovery and regeneration after spinal cord injury in adult rats. — PubMed · 2000 · Journal Article
- Sustained induction of heme oxygenase-1 in the traumatized spinal cord. — PubMed · 2000 · Journal Article
- Efficacy of a new neuroprotective agent, gacyclidine, in a model of rat spinal cord injury. — PubMed · 2000 · Comparative Study
- Persistent accumulation of cyclooxygenase-1 (COX-1) expressing microglia/macrophages and upregulation by endothelium following spinal cord injury. — PubMed · 2000 · Journal Article
- Calcineurin-mediated BAD dephosphorylation activates the caspase-3 apoptotic cascade in traumatic spinal cord injury. — PubMed · 2000 · Journal Article
- Increased calpain expression is associated with apoptosis in rat spinal cord injury: calpain inhibitor provides neuroprotection. — PubMed · 2000 · Journal Article
- Agmatine improves locomotor function and reduces tissue damage following spinal cord injury. — PubMed · 2000 · Journal Article
Where this was looked for, and when
The latest collection walk and the accumulated shelf have different scopes. A zero applies only to that source query and its date window; older records may remain on the shelf. It does not mean no research exists.
| ClinicalTrials.gov | latest collection walk returned no records | asked on 2026-10-05 Collection window: 2026-09-16 – 2026-10-05 | matched in this collection walk 0 · accumulated records across collection walks 6 · still to fetch in this walk 0 | aim: every record matching this question |
|---|---|---|---|---|
| Crossref | asked, and it answered | asked on 2026-09-16 Collection window: all dates before the end date – 2026-09-16 | matched in this collection walk 1230843 · accumulated records across collection walks 50 | aim: a sample of the most relevant records. This source ranks a bag of words, so its own total is the size of the corpus that shares some of them, never a set still owed. |
| PubMed | asked, and it answered | asked on 2026-09-17 Collection window: all dates before the end date – 2026-09-17 | matched in this collection walk 3744 · accumulated records across collection walks 3744 · still to fetch in this walk 0 | aim: every record matching this question |
The question asked
- ClinicalTrials.gov
("neuroprotection" OR "secondary injury") - Crossref
spinal cord injury neuroprotection secondary injury - PubMed
("Spinal Cord Injuries"[MeSH Terms] OR "spinal cord injury"[Title/Abstract] OR "spinal cord injuries"[Title/Abstract] OR "spinal cord trauma"[Title/Abstract]) AND ("Neuroprotection"[MeSH Terms] OR "Neuroprotective Agents"[MeSH Terms] OR "neuroprotection"[Title/Abstract] OR "secondary injury"[Title/Abstract])