A subject this map covers
Gene therapy
What belongs here
Introducing, silencing or editing a gene in nervous-system cells after injury.
What does not belong here, however close it looks
Cells engineered in a dish and then transplanted also belong to cell therapy.
What has been looked at
Counted from what the sources catalogue, not from reading the work. It says how much exists and over what span of years — never what any of it found.
- Registered or indexed as work in people: 185 records · 1992–2026
- Indexed as work in animals: 221 records · 1994–2026
- Indexed as laboratory work: 18 records · 1997–2021
- The source has not said who or what was studied: 99 records · 1997–2026
- Nobody has yet checked any of this against its original for this map, so none of it is on the checked shelf.
Checked
Records a person has read against the original and published into this map. These carry measurements, evidence states and a place on the ladder.
Nobody has checked a record on this subject yet.
Checking is done by a person, one record at a time, and this subject has not reached the queue yet. The shelf below is what the sources hold in the meantime; it has not been read by anybody.
Found in the scientific sources, not yet checked
Titles and identifiers as the sources publish them. Nobody here has read these papers, and nothing on this shelf is a result, a recommendation or evidence that anything works. Each line opens the original.
523 records
This grouping is the source's own cataloguing, not a reading of the paper. It says where a record was filed, not what it found.
Indexed as work in animals
- Effect of adenovirus-mediated basic fibroblast growth factor gene transfer in vivo on oligodendrocyte cell numbers throughout ventrolateral white matter following spinal cord injury in rats. — PubMed · 2012 · Journal Article
- The protective effects of the lentivirus-mediated neuroglobin gene transfer on spinal cord injury in rabbits. — PubMed · 2012 · Journal Article
- Lentiviral vector mediates exogenous gene expression in adult rat DRG following peripheral nerve remote delivery. — PubMed · 2012 · Journal Article
- [Experiment study on the treatment of SCI based on HSV carried BDNF transgene technique]. — PubMed · 2012 · English Abstract
- Lentivirus-siNgR199 promotes axonal regeneration and functional recovery in rats. — PubMed · 2012 · Journal Article
- Hypoxia-specific VEGF-expressing neural stem cells in spinal cord injury model. — PubMed · 2012 · Journal Article
- [Transfection of exogenous gene: Lac Z into spinal cord of SD rats and its protein expression:an in vivo study]. — PubMed · 2012 · English Abstract
- Site-specific gene transfer into the rat spinal cord by photomechanical waves. — PubMed · 2011 · Journal Article
- Bone marrow-derived mesenchymal stem cells expressing the bFGF transgene promote axon regeneration and functional recovery after spinal cord injury in rats. — PubMed · 2011 · Journal Article
- Inhibitor of DNA binding 2 promotes sensory axonal growth after SCI. — PubMed · 2011 · Journal Article
- Comparison of AAV2 and AAV5 in gene transfer in the injured spinal cord of mice. — PubMed · 2011 · Comparative Study
- Delayed intrathecal delivery of RhoA siRNA to the contused spinal cord inhibits allodynia, preserves white matter, and increases serotonergic fiber growth. — PubMed · 2011 · Journal Article
- Neural stem cells modified by a hypoxia-inducible VEGF gene expression system improve cell viability under hypoxic conditions and spinal cord injury. — PubMed · 2011 · Journal Article
- CD47 knockout mice exhibit improved recovery from spinal cord injury. — PubMed · 2011 · Journal Article
- Hypoxia-induced expression of VEGF in the organotypic spinal cord slice culture. — PubMed · 2011 · Journal Article
- Controlled nonviral gene delivery and expression using stable neural stem cell line transfected with a hypoxia-inducible gene expression system. — PubMed · 2010 · Journal Article
- Sustained expression of vascular endothelial growth factor and angiopoietin-1 improves blood-spinal cord barrier integrity and functional recovery after spinal cord injury. — PubMed · 2010 · Journal Article
- Suppression of detrusor-sphincter dyssynergia by herpes simplex virus vector mediated gene delivery of glutamic acid decarboxylase in spinal cord injured rats. — PubMed · 2010 · Journal Article
- Enhanced adenoviral gene delivery to motor and dorsal root ganglion neurons following injection into demyelinated peripheral nerves. — PubMed · 2010 · Journal Article
- Local and remote growth factor effects after primate spinal cord injury. — PubMed · 2010 · Journal Article
- DMM Travelling Fellowship awards. — PubMed · 2010 · Journal Article
- Targeted retrograde gene delivery of brain-derived neurotrophic factor suppresses apoptosis of neurons and oligodendroglia after spinal cord injury in rats. — PubMed · 2010 · Journal Article
- An engineered transcription factor which activates VEGF-A enhances recovery after spinal cord injury. — PubMed · 2010 · Journal Article
- Modification of N-glycosylation sites allows secretion of bacterial chondroitinase ABC from mammalian cells. — PubMed · 2010 · Journal Article
- Role of the oxygen-dependent degradation domain in a hypoxia-inducible gene expression system in vascular endothelial growth factor gene therapy. — PubMed · 2009 · Journal Article
- Guiding regenerating axons to their brainstem targets. — PubMed · 2009 · News
- IL-10 promotes neuronal survival following spinal cord injury. — PubMed · 2009 · Journal Article
- Neurotrophic factor-expressing mesenchymal stem cells survive transplantation into the contused spinal cord without differentiating into neural cells. — PubMed · 2009 · Journal Article
- HSV-mediated transfer of artemin overcomes myelin inhibition to improve outcome after spinal cord injury. — PubMed · 2009 · Journal Article
- Transgenic inhibition of astroglial NF-kappa B leads to increased axonal sparing and sprouting following spinal cord injury. — PubMed · 2009 · Comparative Study
- Combination of microsurgery and gene therapy for spinal dorsal root injury repair. — PubMed · 2009 · Journal Article
- Herpes simplex virus vector-mediated gene delivery of glutamic acid decarboxylase reduces detrusor overactivity in spinal cord-injured rats. — PubMed · 2009 · Evaluation Study
- Regeneration of spinal cord with cell and gene therapy. — PubMed · 2009 · Comparative Study
- Genetic ablation of transcription repressor Bach1 reduces neural tissue damage and improves locomotor function after spinal cord injury in mice. — PubMed · 2009 · Journal Article
- IGF-I gene delivery promotes corticospinal neuronal survival but not regeneration after adult CNS injury. — PubMed · 2009 · Journal Article
- Type I interferon inhibits astrocytic gliosis and promotes functional recovery after spinal cord injury by deactivation of the MEK/ERK pathway. — PubMed · 2009 · Journal Article
- Antisense vimentin cDNA combined with chondroitinase ABC reduces glial scar and cystic cavity formation following spinal cord injury in rats. — PubMed · 2008 · Journal Article
- Adenovirus-mediated retrograde transfer of neurotrophin-3 gene enhances survival of anterior horn neurons of twy/twy mice with chronic mechanical compression of the spinal cord. — PubMed · 2008 · Comparative Study
- Selective gene transfer into neurons via Na,K-ATPase beta1. Targeting gene transfer with monoclonal antibody and adenovirus vector. — PubMed · 2008 · Journal Article
- Ex vivo non-viral vector-mediated neurotrophin-3 gene transfer to olfactory ensheathing glia: effects on axonal regeneration and functional recovery after implantation in rats with spinal cord injury. — PubMed · 2008 · Journal Article
- A novel human foamy virus mediated gene transfer of GAD67 reduces neuropathic pain following spinal cord injury. — PubMed · 2008 · Journal Article
- Analysis of the intracellular barriers encountered by nonviral gene carriers in a model of spatially controlled delivery to neurons. — PubMed · 2008 · Journal Article
- Increased chondroitin sulfate proteoglycan expression in denervated brainstem targets following spinal cord injury creates a barrier to axonal regeneration overcome by chondroitinase ABC and neurotrophin-3. — PubMed · 2008 · Journal Article
- Plasmid-based genetic modification of human bone marrow-derived stromal cells: analysis of cell survival and transgene expression after transplantation in rat spinal cord. — PubMed · 2007 · Journal Article
- Hepatocyte growth factor promotes endogenous repair and functional recovery after spinal cord injury. — PubMed · 2007 · Journal Article
- Gene transfer to interfere with TNFalpha signaling in neuropathic pain. — PubMed · 2007 · Journal Article
- Hypoxia-inducible expression of vascular endothelial growth factor for the treatment of spinal cord injury in a rat model. — PubMed · 2007 · Journal Article
- Brain-derived neurotrophic factor gene transfer with adeno-associated viral and lentiviral vectors prevents rubrospinal neuronal atrophy and stimulates regeneration-associated gene expression after acute cervical spinal cord injury. — PubMed · 2007 · Journal Article
- Fibrillation potentials following spinal cord injury: improvement with neurotrophins and exercise. — PubMed · 2007 · Journal Article
- Induced expression of polysialic acid in the spinal cord promotes regeneration of sensory axons. — PubMed · 2007 · Journal Article
- Rescue of rat anterior horn neurons after spinal cord injury by retrograde transfection of adenovirus vector carrying brain-derived neurotrophic factor gene. — PubMed · 2007 · Journal Article
- A hypoxia-inducible gene expression system using erythropoietin 3' untranslated region for the gene therapy of rat spinal cord injury. — PubMed · 2007 · Journal Article
- Combined treatment of neurotrophin-3 gene and neural stem cells is propitious to functional recovery after spinal cord injury. — PubMed · 2007 · Journal Article
- Lentiviral vector-mediated reporter gene expression in avulsed spinal ventral root is short-term, but is prolonged using an immune "stealth" transgene. — PubMed · 2007 · Journal Article
- Growth factor treatment and genetic manipulation stimulate neurogenesis and oligodendrogenesis by endogenous neural progenitors in the injured adult spinal cord. — PubMed · 2006 · Journal Article
- Lentiviral vector expressing retinoic acid receptor beta2 promotes recovery of function after corticospinal tract injury in the adult rat spinal cord. — PubMed · 2006 · Journal Article
- Targeted retrograde transfection of adenovirus vector carrying brain-derived neurotrophic factor gene prevents loss of mouse (twy/twy) anterior horn neurons in vivo sustaining mechanical compression. — PubMed · 2006 · Journal Article
- Genetic manipulation of intraspinal plasticity after spinal cord injury alters the severity of autonomic dysreflexia. — PubMed · 2006 · Journal Article
- Suitability of allogeneic sertoli cells for ex vivo gene delivery in the injured spinal cord. — PubMed · 2006 · Comparative Study
- Use of engineered peripheral nerve autografts for spinal cord repair. — PubMed · 2006 · Comparative Study
Where this was looked for, and when
The exact question each source was asked, the day it was asked, and what came back. A zero on this page is only honest if these are on it.
| ClinicalTrials.gov | asked, and it has nothing | asked on 2026-09-29 | the source found 0 · this programme has 2 · still to fetch 0 | aim: every record matching this question |
|---|---|---|---|---|
| Crossref | asked, and it answered | asked on 2026-09-16 | the source found 3660371 · this programme has 50 | aim: a sample of the most relevant records. This source ranks a bag of words, so its own total is the size of the corpus that shares some of them, never a set still owed. |
| PubMed | asked, and it answered | asked on 2026-10-12 | the source found 1 · this programme has 495 · still to fetch 0 | aim: every record matching this question |
The question asked
- ClinicalTrials.gov
("gene therapy" OR "gene delivery") - Crossref
spinal cord injury gene therapy gene delivery - PubMed
("Spinal Cord Injuries"[MeSH Terms] OR "spinal cord injury"[Title/Abstract] OR "spinal cord injuries"[Title/Abstract] OR "spinal cord trauma"[Title/Abstract]) AND ("Genetic Therapy"[MeSH Terms] OR "gene therapy"[Title/Abstract] OR "gene delivery"[Title/Abstract])